413 research outputs found
Structural properties and quasiparticule energies of cubic SrO, MgO and SrTiO3
The structural properties and the band structures of the charge-transfer
insulating oxides SrO, MgO and SrTiO3 are computed both within density
functional theory in the local density approximation (LDA) and in the Hedin's
GW scheme for self-energy corrections, by using a model dielectric function,
which approximately includes local field and dynamical effects. The deep
valence states are shifted by the GW method to higher binding energies, in very
good agreement with photoemission spectra. Since in all of these oxides the
direct gaps at high-symmetry points of the Brillouin zone may be very sensitive
to the actual value of the lattice parameter a, already at the LDA level,
self-energy corrections are computed both at the theoretical and the
experimental a. For MgO and SrO, the values of the transition energies between
the valence and the conduction bands are improved by GW corrections, while for
SrTiO3 they are overestimated. The results are discussed in relation to the
importance of local field effects and to the nature of the electronic states in
these insulating oxides.Comment: 3 figures, accepted in J. Phys.: Condens. Matte
Fast atom diffraction inside a molecular beam epitaxy chamber, a rich combination
Two aspects of the contribution of grazing incidence fast atom diffraction
(GIFAD) to molecular beam epitaxy (MBE) are reviewed here: the ability of GIFAD
to provide \emph{in-situ} a precise description of the atomic-scale surface
topology, and its ability to follow larger-scale changes in surface roughness
during layer-by-layer growth. Recent experimental and theoretical results
obtained for the He atom beam incident along the highly corrugated direction of the (24) reconstructed GaAs(001) surface are
summarized and complemented by the measurements and calculations for the beam
incidence along the weakly corrugated [010] direction where a periodicity twice
smaller as expected is observed. The combination of the experiment, quantum
scattering matrix calculations, and semiclassical analysis allows in this case
to reveal structural characteristics of the surface. For the in situ
measurements of GIFAD during molecular beam epitaxy of GaAs on GaAs surface we
analyse the change in elastic and inelastic contributions in the scattered
beam, and the variation of the diffraction pattern in polar angle scattering.
This analysis outlines the robustness, the simplicity and the richness of the
GIFAD as a technique to monitor the layer-by-layer epitaxial growth
Shock-Wave Heating Model for Chondrule Formation: Prevention of Isotopic Fractionation
Chondrules are considered to have much information on dust particles and
processes in the solar nebula. It is naturally expected that protoplanetary
disks observed in present star forming regions have similar dust particles and
processes, so study of chondrule formation may provide us great information on
the formation of the planetary systems.
Evaporation during chondrule melting may have resulted in depletion of
volatile elements in chondrules. However, no evidence for a large degree of
heavy-isotope enrichment has been reported in chondrules. In order to meet this
observed constraint, the rapid heating rate at temperatures below the silicate
solidus is required to suppress the isotopic fractionation.
We have developed a new shock-wave heating model taking into account the
radiative transfer of the dust thermal continuum emission and the line emission
of gas molecules and calculated the thermal history of chondrules. We have
found that optically-thin shock waves for the thermal continuum emission from
dust particles can meet the rapid heating constraint, because the dust thermal
emission does not keep the dust particles high temperature for a long time in
the pre-shock region and dust particles are abruptly heated by the gas drag
heating in the post-shock region. We have also derived the upper limit of
optical depth of the pre-shock region using the radiative diffusion
approximation, above which the rapid heating constraint is not satisfied. It is
about 1 - 10.Comment: 58 pages, including 5 tables and 15 figures, accepted for publication
in The Astrophysical Journa
gp91phox-dependent expression of platelet CD40 ligand
Background-CD40 ligand (CD40L) expression on platelets is mediated by agonists, but the underlying mechanism is still unclear. Methods and Results-CD40L expression was measured in platelets from healthy subjects both with and without the addition of antioxidants or a phospholipase A2 (PLA2) inhibitor and in platelets from 2 patients with an inherited deficiency of gp91phox. Immunoprecipitation analysis was also performed to determine whether normal platelets showed gp91phox expression. Unlike catalase and mannitol, superoxide dismutase inhibited agonist-induced platelet CD40L expression in healthy subjects. Immunoprecipitation analysis also showed that platelets from healthy subjects expressed gp91phox. In 2 male patients with inherited gp91phox deficiency, collagen-, thrombin-, and arachidonic acid-stimulated platelets showed an almost complete absence of superoxide anion (O2-) and CD40L expression. Incubation of platelets from healthy subjects with a PLA2 inhibitor almost completely prevented agonist-induced O2- and CD40L expression. Conclusions-These data provide the first evidence that platelet CD40L expression occurs via arachidonic acid-mediated gp91phox activation
PDE11A gene polymorphism in testicular cancer: sperm parameters and hormonal profile
Purpose: Testicular germ cell tumours (TGCTs) is the most common malignancy among young adult males. The etiology is multifactorial and both environmental and genetic factors play an important role in the origin and development of TGCT. Genetic susceptibility may result from the interaction of multiple common and low-penetrance genetic variants and one of the main candidate genes is PDE11A. Many PDE11A polymorphisms were found responsible for a reduced PDE activity in TGCT patients, who often also display impaired hormone and sperm profile. The aim of this study was to investigate testicular function and PDE11A sequence in testicular cancer cases. Methods: Semen analysis was performed in 116 patients with unilateral and bilateral sporadic TGCTs and in 120 cancer-free controls. We also investigated hormone profile and PDE11A polymorphisms using peripheral blood samples. Results: Our data revealed that TGCT patients showed lower testosterone levels, higher gonadotropins levels and worse semen quality than controls, although the mean and the medians of sperm parameters are within the reference limits. PDE11A sequencing detected ten polymorphisms not yet associated with TGCTs before. Among these, G223A in homozygosity and A288G in heterozygosity were significantly associated with a lower risk of testicular tumour and they displayed a positive correlation with total sperm number. Conclusions: Our findings highlight the key role of PDE11A in testis and suggest the presence of an underlying complex and fine molecular mechanism which controls testis-specific gene expression and susceptibility to testicular cancer
Immunization status of internationally adopted children in Rome, Italy
Aims: International adoption medicine is a relatively new specialty in pediatrics that has emerged to address the specific health care needs of internationally adopted children in highâincome countries. This study ascertains the seroprotection rate for vaccineâpreventable diseases, especially against pneumococcal diseases.Patients and Methods: We evaluated 67 internationally adopted children that reached the International Adoption Unit of Bambino GesĂč Childrenâs Hospital, RomeâItaly. We collected demographic information, data from preadoption immunization records, results of laboratory testing for immunity to vaccineâpreventable diseases (tetanus, pneumococcus, hepatitis B, hemophilus influenzae type b (Hib), measles), as well as results of screening for HIV, hepatitis C, quantiferon, immunological and nutritional status.Results: For children that had received â„3 vaccine doses of tetanus, overall protection was 94% of 31 vaccinated children; with 1â2 vaccine doses for hepatitis B and Hib respectively, protection was 45% of 29 vaccinated children and 63% of 8 vaccinated children, respectively. For children with one or more doses of measles vaccine, protection was 63% of 32 vaccinated children. Regarding pneumococcus vaccine (documented for eight children), 88% of children with one or more doses of vaccine had developed protective immunity.Conclusions: International adoptees without a valid vaccine record need to undergo a complete schedule in accordance with their age and should receive all the vaccines in the adoptive countryâs schedule.Key words: And pneumococcal immunization, immigrant children, internationally adopted children, vaccination statu
Legal Status and the Criminal Activity of Immigrants
We exploit exogenous variation in legal status following the January 2007 European Union enlargement to estimate its effect on immigrant crime. We difference out unobserved time-varying factors by (i) comparing recidivism rates of immigrants from the ânewâ and âcandidateâ member countries; and (ii) using arrest data on for eign detainees released upon a mass clemency that occurred in Italy in August 2006. The timing of the two events allows us to setup a difference-in-differences strategy. Legal status leads to a 50 percent reduction in recidivism, and explains one-half to two-thirds of the observed differences in crime rates between legal and illegal immigrants
Atomic Diagnostics of X-ray Irradiated Protoplanetary Disks
We study atomic line diagnostics of the inner regions of protoplanetary disks
with our model of X-ray irradiated disk atmospheres which was previously used
to predict observable levels of the NeII and NeIII fine-structure transitions
at 12.81 and 15.55mum. We extend the X-ray ionization theory to sulfur and
calculate the fraction of sulfur in S, S+, S2+ and sulfur molecules. For the
D'Alessio generic T Tauri star disk, we find that the SI fine-structure line at
25.55mum is below the detection level of the Spitzer Infrared Spectrometer
(IRS), in large part due to X-ray ionization of atomic S at the top of the
atmosphere and to its incorporation into molecules close to the mid-plane. We
predict that observable fluxes of the SII 6718/6732AA forbidden transitions are
produced in the upper atmosphere at somewhat shallower depths and smaller radii
than the neon fine-structure lines. This and other forbidden line transitions,
such as the OI 6300/6363AA and the CI 9826/9852AA lines, serve as complementary
diagnostics of X-ray irradiated disk atmospheres. We have also analyzed the
potential role of the low-excitation fine-structure lines of CI, CII, and OI,
which should be observable by SOFIA and Herschel.Comment: Accepted by Ap
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