Stosowanie Konstytucji RP z 1997 roku - doświadczenia i perspektywy : międzynarodowa konferencja naukowa

Sprawozdanie z Międzynarodowej Konferencji Naukowej, która odbyła się w Krakowie w dniach 24-27 września 2006Prowadzone w latach 2002-2005 przez kilkudziesięciu specjalistów z całej Polski, pod kierownictwem prof. dr hab. Kazimierza Działochy, badania nad stosowaniem Konstytucji RP z 1997 r. przyniosły nie tylko bogaty dorobek liczący dziesięć tomów studiów i raport końcowy, ale znalazły swój finał w pracach Międzynarodowej Konferencji Naukowej, która odbyła się w Krakowie w dniach 24-27 września 2006 r. Konferencja zorganizowana została przez Polskie Towarzystwo Prawa Konstytucyjnego, Katedrę Prawa Ustrojowego Uniwersytetu Jagiellońskiego oraz Katedrę Prawa Konstytucyjnego Krakowskiej Szkoły Wyższej im. Andrzeja Frycza Modrzewskiego. Wybitne osobistości ze świata nauki i praktyki politycznej - zwłaszcza współtwórcy Konstytucji - oraz osoby zajmujące najwyższe stanowiska państwowe, które stosowały ją bezpośrednio, tworzyły Komitet Honorowy Konferencji pod przewodnictwem pana Prezydenta Aleksandra Kwaśniewskiego

The role of the diffusion in the predictions of the classical nucleation theory for quasi‑real systems differ in dipole moment value

In this paper, we examine the crystallization tendency for two quasi-real systems, which differ exclusively in the dipole moment’s value. The main advantage of the studied system is the fact that despite that their structures are entirely identical, they exhibit different physical properties. Hence, the results obtained for one of the proposed model systems cannot be scaled to reproduce the results for another corresponding system, as it can be done for simple model systems, where structural differences are modeled by the different parameters of the intermolecular interactions. Our results show that both examined systems exhibit similar stability behavior below the melting temperature. This finding is contrary to the predictions of the classical nucleation theory, which suggests a significantly higher crystallization tendency for a more polar system. Our studies indicate that the noted discrepancies are caused by the kinetic aspect of the classical nucleation theory, which overestimates the role of diffusion in the nucleation process

REM-OSA as a Tool to Understand Both the Architecture of Sleep and Pathogenesis of Sleep Apnea—Literature Review

Sleep is a complex physiological state, which can be divided into the non-rapid eye movement (NREM) phase and the REM phase. Both have some unique features and functions. This difference is best visible in electroencephalography recordings, respiratory system activity, arousals, autonomic nervous system activity, or metabolism. Obstructive sleep apnea (OSA) is a common condition characterized by recurrent episodes of pauses in breathing during sleep caused by blockage of the upper airways. This common condition has multifactorial ethiopathogenesis (e.g., anatomical predisposition, sex, obesity, and age). Within this heterogenous syndrome, some distinctive phenotypes sharing similar clinical features can be recognized, one of them being REM sleep predominant OSA (REM-OSA). The aim of this review was to describe the pathomechanism of REM-OSA phenotype, its specific clinical presentation, and its consequences. Available data suggest that in this group of patients, the severity of specific cardiovascular and metabolic complications is increased. Due to the impact of apneas and hypopneas predominance during REM sleep, patients are more prone to develop hypertension or glucose metabolism impairment. Additionally, due to the specific function of REM sleep, which is predominantly fragmented in the REM-OSA, this group presents with decreased neurocognitive performance, reflected in memory deterioration, and mood changes including depression. REM-OSA clinical diagnosis and treatment can alleviate these outcomes, surpassing the traditional treatment and focusing on a more personalized approach, such as using longer therapy of continuous positive airway pressure or oral appliance use

Table_2_Evaluation of daytime sleepiness and insomnia symptoms in OSA patients with a characterization of symptom-defined phenotypes and their involvement in depression comorbidity—a cross-sectional clinical study.docx

IntroductionRecent research highlights the significance of insomnia and sleepiness, shifting from obstructive sleep apnea (OSA) severity and sleep structure, in defining OSA phenotypes.ObjectivesThis study aimed to characterize insomnia and sleepiness associated with OSA phenotypes and assess their involvement in depression symptoms (DS) in OSA.Materials and methodsThis cross-sectional, clinical study included 181 participants who underwent polysomnography (PSG) and filled out questionnaires, including the Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), and Beck Depression Index (BDI). They were categorized into phenotypes: insomnia–sleepiness (I + S; ESS ≥ 11; ISI ≥ 15; n = 20), sleepiness (S; ESS ≥ 11; ISI ResultsA linear regression model for the BDI score (R2 = 0.357, p ConclusionUsing clinical features for OSA phenotyping holds promise for finding OSA individuals with increased risk for DS occurrence.</p

Table_3_Evaluation of daytime sleepiness and insomnia symptoms in OSA patients with a characterization of symptom-defined phenotypes and their involvement in depression comorbidity—a cross-sectional clinical study.docx

IntroductionRecent research highlights the significance of insomnia and sleepiness, shifting from obstructive sleep apnea (OSA) severity and sleep structure, in defining OSA phenotypes.ObjectivesThis study aimed to characterize insomnia and sleepiness associated with OSA phenotypes and assess their involvement in depression symptoms (DS) in OSA.Materials and methodsThis cross-sectional, clinical study included 181 participants who underwent polysomnography (PSG) and filled out questionnaires, including the Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), and Beck Depression Index (BDI). They were categorized into phenotypes: insomnia–sleepiness (I + S; ESS ≥ 11; ISI ≥ 15; n = 20), sleepiness (S; ESS ≥ 11; ISI ResultsA linear regression model for the BDI score (R2 = 0.357, p ConclusionUsing clinical features for OSA phenotyping holds promise for finding OSA individuals with increased risk for DS occurrence.</p

Table_1_Evaluation of daytime sleepiness and insomnia symptoms in OSA patients with a characterization of symptom-defined phenotypes and their involvement in depression comorbidity—a cross-sectional clinical study.docx

IntroductionRecent research highlights the significance of insomnia and sleepiness, shifting from obstructive sleep apnea (OSA) severity and sleep structure, in defining OSA phenotypes.ObjectivesThis study aimed to characterize insomnia and sleepiness associated with OSA phenotypes and assess their involvement in depression symptoms (DS) in OSA.Materials and methodsThis cross-sectional, clinical study included 181 participants who underwent polysomnography (PSG) and filled out questionnaires, including the Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), and Beck Depression Index (BDI). They were categorized into phenotypes: insomnia–sleepiness (I + S; ESS ≥ 11; ISI ≥ 15; n = 20), sleepiness (S; ESS ≥ 11; ISI ResultsA linear regression model for the BDI score (R2 = 0.357, p ConclusionUsing clinical features for OSA phenotyping holds promise for finding OSA individuals with increased risk for DS occurrence.</p