1,410 research outputs found

    Supersymmetric Yang-Mills, octonionic instantons and triholomorphic curves

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    In four-dimensional gauge theory there exists a well-known correspondence between instantons and holomorphic curves, and a similar correspondence exists between certain octonionic instantons and triholomorphic curves. We prove that this latter correspondence stems from the dynamics of various dimensional reductions of ten-dimensional supersymmetric Yang-Mills theory. More precisely we show that the dimensional reduction of the (5+1)-dimensional supersymmetric sigma model with hyperkaehler (but otherwise arbitrary) target X to a four-dimensional hyperkaehler manifold M is a topological sigma model localising on the space of triholomorphic maps M -> X (or hyperinstantons). When X is the moduli space M_K of instantons on a four-dimensional hyperkaehler manifold K, this theory has an interpretation in terms of supersymmetric gauge theory. In this case, the topological sigma model can be understood as an adiabatic limit of the dimensional reduction of ten-dimensional supersymmetric Yang-Mills on the eight-dimensional manifold M x K of holonomy Sp(1) x Sp(1) in Spin(7), which is a cohomological theory localising on the moduli space of octonionic instantons.Comment: 26 pages, LaTeX2e (A comment and a corresponding acknowledgement added and a reference ammended

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    GaHV-2 ICP22 protein is expressed from a bicistronic transcript regulated by three GaHV-2 microRNAs

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    International audienceHerpesviruses have a lifecycle consisting of successive lytic, latent and reactivation phases. Only three infected cell proteins (ICPs) have been described for the oncogenic Marek's disease virus (or Gallid herpes virus 2, GaHV-2): ICP4, ICP22 and ICP27. We focus here on ICP22, confirming its cytoplasmic location and showing that ICP22 is expressed during productive phases of the lifecycle, via a bicistronic transcript encompassing the US10 gene. We also identified the unique promoter controlling ICP22 expression, and its core promoter, containing functional responsive elements including E-box, ETS-1 and GATA elements involved in ICP22 transactivation. ICP22 gene expression was weakly regulated by DNA methylation and activated by ICP4 or ICP27 proteins. We also investigated the function of GaHV-2 ICP22. We found that this protein repressed transcription from its own promoter and from those of IE ICP4 and ICP27, and the late gK promoter. Finally, we investigated posttranscriptional ICP22 regulation by GaHV-2 microRNAs. We found that mdv1-miR-M5-3p and -M1-5p downregulated ICP22 mRNA expression during latency, whereas, unexpectedly, mdv1-miR-M4-5p upregulated the expression of the protein ICP22, indicating a tight regulation of ICP22 expression by microRNAs

    An algebraic Birkhoff decomposition for the continuous renormalization group

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    This paper aims at presenting the first steps towards a formulation of the Exact Renormalization Group Equation in the Hopf algebra setting of Connes and Kreimer. It mostly deals with some algebraic preliminaries allowing to formulate perturbative renormalization within the theory of differential equations. The relation between renormalization, formulated as a change of boundary condition for a differential equation, and an algebraic Birkhoff decomposition for rooted trees is explicited

    El contagio de el Peñón que acredita los famosos Tropheos de la Facultad Médica : individual descripción de la constitución pestilente que padeció aquella Plaza en el año 1743

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    Edición facsímil de la publicación original impresa en Málaga, en 1744 por Thomas Exarch, Juan de Figueroa y Joseph Serrano
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