Asymmetric Gaussian steering: when Alice and Bob disagree

Asymmetric steering is an effect whereby an inseparable bipartite system can be found to be described by either quantum mechanics or local hidden variable theories depending on which one of Alice or Bob makes the required measurements. We show that, even with an inseparable bipartite system, situations can arise where Gaussian measurements on one half are not sufficient to answer the fundamental question of which theory gives an adequate description and the whole system must be considered. This phenomenon is possible because of an asymmetry in the definition of the original Einstein-Podolsky-Rosen paradox and in this article we show theoretically that it may be demonstrated, at least in the case where Alice and Bob can only make Gaussian measurements, using the intracavity nonlinear coupler.Comment: 5 Pages, 4 Figure

The Compliance with Intellectual Property Laws and their Enforcement in Jordan- A post-WTO Review & Analysis

This thesis examines the implementation, enforcement and evolution of IP laws and regulations in the Hashemite Kingdom of Jordan. The period of interest includes the last decade of the twentieth century and the first decade of the twenty first century, with emphasis on the role played by Free Trade Agreements struck between Jordan and the United States, the European Union, and Jordan’s accession to the World Trade Organization. This thesis also examines the enforcement of the current set of IP laws in Jordan, and looks at their social and economic compatibility with the Jordanian societal norms and economic realities. This thesis argues that Jordanian IP laws lack a meaningful social and economic texture, and have failed to be evenly enforced in Jordan, essentially because they do not fit the Jordanian culture and are not compatible with Jordan’s economic stage of development. Additionally, the thesis argues that IP laws have had insignificant economic impact on the Jordanian economy as the majority of technologies used in Jordan, and the majority of foreign direct investments attracted to Jordan, are not IP related. Finally, the thesis argues that the current Jordanian enforcement model, which is built on coercion by donor countries, is serving the interests of foreign companies to the exclusion of the local citizens, and will not, in the long run, produce an enforcement model based on self-regulation by Jordanians, themselves. The laws, therefore, are unable to produce tangible results for the Jordanian people, or help meet their economic interests. The last part of the thesis deals with recommendations and suggestions aimed at creating an integrated approach to the adoption of IP policies

Detection of continuous variable entanglement without coherent local oscillators

We propose three criteria for identifying continuous variable entanglement between two many-particle systems with no restrictions on the quantum state of the local oscillators used in the measurements. Mistakenly asserting a coherent state for the local oscillator can lead to incorrectly identifying the presence of entanglement. We demonstrate this in simulations with 100 particles, and also find that large number fluctuations do not prevent the observation of entanglement. Our results are important for quantum information experiments with realistic Bose-Einstein condensates or in optics with arbitrary photon states.Comment: 7 Pages, 4 Figure

A Vineyard in a Law Clinic: The Practical Application of a Therapeutic Jurisprudence Philosophy in a UK Law Clinic

In late 2015, the British Red Cross approached the lead author. It was increasingly evident that given the austerity-driven political agenda of the UK government in cutting public funding to advisory services, coupled with the developing refugee crisis and its impact on countries and regions, refugees in many parts of the UK were in need of legal and non-legal assistance. University law clinics were an obvious source of support given their objectives of developing students’ understanding and engagement with community groups. As our law clinic, based in the Helena Kennedy Centre for International Justice (HKC), was developed specifically to address the needs of groups such as refugees, and given the ground-breaking work of Wexler and Winick (in Therapeutic Jurisprudence) and Gould and Perlin (on its application to clinical legal education) on providing a therapeutically positive experience for users, we sought to base our clinic aligned with Therapeutic Jurisprudence (TJ) principles. This paper examines the development and practical operation of a law clinic from a TJ perspective

Regulation of HPV16 E6 and MCL1 by SF3B1 inhibitor in head and neck cancer cells

ABT-737 inhibits the anti-apoptotic proteins B-cell lymphoma 2 (BCL-2) and BCL-X L. Meayamycin B switches the splicing pattern of myeloid cell leukemia factor 1 (MCL1) pre-mRNA. Specifically, inhibition of splicing factor 3B subunit 1 (SF3B1) with meayamycin B promotes the generation of the proapoptotic, short splicing variant (MCL1-S) and diminishes the antiapoptotic, long variant (MCL1-L). This action was previously associated with the cytotoxicity of meayamycin B in non-small cell lung carcinoma cell lines. ABT-737 induced apoptosis in response to an ablation of MCL1-L by meayamycin B. In this study, we further exploited this synergistic combination in head and neck squamous cell carcinoma (HNSCC), up to 90% of which overexpress MCL1 and BCL-X L. In a panel of seven HNSCC cell lines, the combination of meayamycin B and ABT-737 rapidly triggered a Bax/Bak-mediated apoptosis that overcame the resistance from HPV16-positive HNSCC against each agent alone. Both RT-PCR and Western blotting showed that meayamycin B up-regulated MCL1-S and down-regulated MCL1-L. Significantly, we discovered that SF3B1 was involved in the splicing of oncogenic HPV16 E6 to produce non-oncogenic HPV16 E6*, indicating that SF3B1 may inhibit HPV16-induced tumorigenesis

Enhancing Biodiversity and Multifunctionality of an Organic Farmscape in California’s Central Valley

Organic farmers in the USA increasingly manage the margins of previously monocultured farmed landscapes to increase biodiversity, e.g. they restore and protect riparian corridors, plant hedgerows and construct vegetated tailwater ponds. This study attempts to link habitat enhancements, biodiversity and changes in ecosystem functions by: 1. inventorying the existing biodiversity and the associated belowground community structure and composition in the various habitats of an organic farm in California’s Central Valley; and 2. monitoring key ecosystem functions of these habitats. Two years of inventories show greater native plant diversity in non-cropped areas. While nematode diversity did not differ between habitats, functional groups were clearly associated with particular habitats as were soil microbial communities (phospholipid fatty acid analysis). Earthworm diversity did not differ between habitats, but biomass was higher in non-cropped areas. Habitats with woody vegetation stored 20% of the farmscape’s total carbon (C), despite their relatively small size (only 5% of the total farm). Two years of monitoring data of farmscape C and nitrogen (N) through emissions, run-off and leaching showed distinct tradeoffs in function associated with each habitat. Clearly habitat restoration in field margins will increase both landscape biodiversity and the multifunctionality of the farmscape as a whole

Harms from other people's drinking: an international survey of their occurrence, impacts on feeling safe and legislation relating to their control.

OBJECTIVE: To examine factors associated with suffering harm from another person's alcohol consumption and explore how suffering such harms relate to feelings of safety in nightlife. DESIGN: Cross-sectional opportunistic survey (Global Drug Survey) using an online anonymous questionnaire in 11 languages promoted through newspapers, magazines and social media. SUBJECTS: Individuals (participating November 2014-January 2015) aged 18-34 years, reporting alcohol consumption in the past 12 months and resident in a country providing ≥250 respondents (n=21 countries; 63 725 respondents). MAIN OUTCOME MEASURES: Harms suffered due to others' drinking in the past 12 months, feelings of safety on nights out (on the way out, in bars/pubs, in nightclubs and when travelling home) and knowledge of over-serving laws and their implementation. RESULTS: In the past 12 months, >40% of respondents suffered at least one aggressive (physical, verbal or sexual assault) harm and 59.5% any harm caused by someone drunk. Suffering each category of harm was higher in younger respondents and those with more harmful alcohol consumption patterns. Men were more likely than women to have suffered physical assault (9.2% vs 4.7; p<0.001), with women much more likely to suffer sexual assault or harassment (15.3% vs 2.5%; p<0.001). Women were more likely to feel unsafe in all nightlife settings, with 40.8% typically feeling unsafe on the way home. In all settings, feeling unsafe increased with experiencing more categories of aggressive harm by a drunk person. Only 25.7% of respondents resident in countries with restrictions on selling alcohol to drunks knew about such laws and 75.8% believed that drunks usually get served alcohol. CONCLUSIONS: Harms from others' drinking are a threat to people's health and well-being. Public health bodies must ensure that such harms are reflected in measures of the societal costs of alcohol, and must advocate for the enforcement of legislation designed to reduce such harms