Characterization of infectious and defective cloned avian hepadnavirus genomes

The infectivity in vivo, replication competence in vitro, and expression of viral genes of several molecularly cloned duck hepatitis B virus (DHBV) genomes were investigated. In addition, replication competence, core protein expression, and secretion of viral proteins were investigated for a grey heron hepatitis B virus genome. Except two, all DHBV isolates tested induced a systemic infection in Pekin ducks when injected as cloned viral DNA into the liver. After transfection of chicken hepatoma cells, both defective DHBV genomes expressed intracellular nucleocapsid and pre-S envelope proteins and secreted DHBs/pre-S particles into the medium. One of the defective DHBV genomes and HHBV produced within the cells replicative intermediates encapsidated in core particles and secreted virions, whereas the other defective DHBV genome did not and was unable to efficiently encapsidate the RNA pregenome. Comparative sequence analysis was performed to identify potential amino acid changes in viral proteins of both defective DHBV genomes. The data obtained demonstrate that most cloned avian hepadnaviruses are infectious or replication competent and suggest defects in envelope, polymerase or encapsidation function, respectively, in two cloned DHBV genomes

Electrical and Structural Properties of \u3ci\u3ep-n\u3c/i\u3e Junctions in cw Laser Annealed Silicon

Depth profiles of the electrical quality of ion implanted and cw laser annealed p-n junctions in silicon are obtained for the first time by secondary ion mass spectroscopy. A comparison with the crystallographic properties of the surface and the junction as observed by Nomarski optical microscopy as well as cross-sectional and plan view transmission electron microscopy is made. Samples containing slip dislocations show better insulation and a lower reverse bias current across the p-n junction as compared to samples with a perfect surface in agreement with current-voltage characteristics. Small dislocation loops located at the junction are found to degrade the junction quality

Dispersive detection of radio-frequency-dressed states

We introduce amethod to dispersively detect alkali-metal atoms in radio-frequency-dressed states. In particular, we use dressed detection tomeasure populations and population differences of atoms prepared in their clock states. Linear birefringence of the atomic medium enables atom number detection via polarization homodyning, a form of common path interferometry. In order to achieve low technical noise levels, we perform optical sideband detection after adiabatic transformation of bare states into dressed states. The balanced homodyne signal then oscillates independently of field fluctuations at twice the dressing frequency, thus allowing for robust, phase-locked detection that circumvents low-frequency noise. Using probe pulses of two optical frequencies, we can detect both clock states simultaneously and obtain population difference as well as the total atom number. The scheme also allows for difference measurements by direct subtraction of the homodyne signals at the balanced detector, which should technically enable quantum noise limited measurements with prospects for the preparation of spin squeezed states. The method extends to other Zeeman sublevels and can be employed in a range of atomic clock schemes, atom interferometers, and other experiments using dressed atoms

A large sample study of spin relaxation and magnetometric sensitivity of paraffin-coated Cs vapor cells

We have manufactured more than 250 nominally identical paraffin-coated Cs vapor cells (30 mm diameter bulbs) for multi-channel atomic magnetometer applications. We describe our dedicated cell characterization apparatus. For each cell we have determined the intrinsic longitudinal, \sGamma{01}, and transverse, \sGamma{02}, relaxation rates. Our best cell shows \sGamma{01}/2\pi\approx 0.5 Hz, and \sGamma{02}/2\pi\approx 2 Hz. We find a strong correlation of both relaxation rates which we explain in terms of reservoir and spin exchange relaxation. For each cell we have determined the optimal combination of rf and laser powers which yield the highest sensitivity to magnetic field changes. Out of all produced cells, 90% are found to have magnetometric sensitivities in the range of 9 to 30 fTHz. Noise analysis shows that the magnetometers operated with such cells have a sensitivity close to the fundamental photon shot noise limit

Two-dimensional array of microtraps with atomic shift register on a chip

Arrays of trapped atoms are the ideal starting point for developing registers comprising large numbers of physical qubits for storing and processing quantum information. One very promising approach involves neutral atom traps produced on microfabricated devices known as atom chips, as almost arbitrary trap configurations can be realised in a robust and compact package. Until now, however, atom chip experiments have focused on small systems incorporating single or only a few individual traps. Here we report experiments on a two-dimensional array of trapped ultracold atom clouds prepared using a simple magnetic-film atom chip. We are able to load atoms into hundreds of tightly confining and optically resolved array sites. We then cool the individual atom clouds in parallel to the critical temperature required for quantum degeneracy. Atoms are shuttled across the chip surface utilising the atom chip as an atomic shift register and local manipulation of atoms is implemented using a focused laser to rapidly empty individual traps.Comment: 6 pages, 4 figure

Nonlinear atom interferometer surpasses classical precision limit

Interference is fundamental to wave dynamics and quantum mechanics. The quantum wave properties of particles are exploited in metrology using atom interferometers, allowing for high-precision inertia measurements [1, 2]. Furthermore, the state-of-the-art time standard is based on an interferometric technique known as Ramsey spectroscopy. However, the precision of an interferometer is limited by classical statistics owing to the finite number of atoms used to deduce the quantity of interest [3]. Here we show experimentally that the classical precision limit can be surpassed using nonlinear atom interferometry with a Bose-Einstein condensate. Controlled interactions between the atoms lead to non-classical entangled states within the interferometer; this represents an alternative approach to the use of non-classical input states [4-8]. Extending quantum interferometry [9] to the regime of large atom number, we find that phase sensitivity is enhanced by 15 per cent relative to that in an ideal classical measurement. Our nonlinear atomic beam splitter follows the "one-axis-twisting" scheme [10] and implements interaction control using a narrow Feshbach resonance. We perform noise tomography of the quantum state within the interferometer and detect coherent spin squeezing with a squeezing factor of -8.2dB [11-15]. The results provide information on the many-particle quantum state, and imply the entanglement of 170 atoms [16]

Microwave spectroscopy of radio-frequency-dressed 87Rb

We study the hyper fine spectrum of atoms of 87Rb dressed by a radio-frequency field and present experimental results in three different situations: freely falling atoms, atoms trapped in an optical dipole trap, and atoms in an adiabatic radio-frequency dressed shell trap. In all cases, we observe several resonant sidebands spaced (in frequency) at intervals equal to the dressing frequency, corresponding to transitions enabled by the dressing field. We theoretically explain the main features of the microwave spectrum using a semiclassical model in the low-field limit and the rotating-wave approximation for alkali-metal-like species, in general, and 87Rb atoms, in particular. As a proof of concept, we demonstrate how the spectral signal of a dressed atomic ensemble enables an accurate determination of the dressing configuration and the probing microwave field

Towards rotation sensing with a single atomic clock

We discuss a scheme to implement a gyroscopic atom sensor with magnetically trapped ultra-cold atoms. Unlike standard light or matter wave Sagnac interferometers no free wave propagation is used. Interferometer operation is controlled only with static, radio-frequency and microwave magnetic fields, which removes the need for interferometric stability of optical laser beams. Due to the confinement of atoms, the scheme may allow the construction of small scale portable sensors. We discuss the main elements of the scheme and report on recent results and efforts towards its experimental realization

Nanofabrication by magnetic focusing of supersonic beams

We present a new method for nanoscale atom lithography. We propose the use of a supersonic atomic beam, which provides an extremely high-brightness and cold source of fast atoms. The atoms are to be focused onto a substrate using a thin magnetic film, into which apertures with widths on the order of 100 nm have been etched. Focused spot sizes near or below 10 nm, with focal lengths on the order of 10 microns, are predicted. This scheme is applicable both to precision patterning of surfaces with metastable atomic beams and to direct deposition of material.Comment: 4 pages, 3 figure

Quantum memory for entangled two-mode squeezed states

A quantum memory for light is a key element for the realization of future quantum information networks. Requirements for a good quantum memory are (i) versatility (allowing a wide range of inputs) and (ii) true quantum coherence (preserving quantum information). Here we demonstrate such a quantum memory for states possessing Einstein-Podolsky-Rosen (EPR) entanglement. These multi-photon states are two-mode squeezed by 6.0 dB with a variable orientation of squeezing and displaced by a few vacuum units. This range encompasses typical input alphabets for a continuous variable quantum information protocol. The memory consists of two cells, one for each mode, filled with cesium atoms at room temperature with a memory time of about 1msec. The preservation of quantum coherence is rigorously proven by showing that the experimental memory fidelity 0.52(2) significantly exceeds the benchmark of 0.45 for the best possible classical memory for a range of displacements.Comment: main text 5 pages, supplementary information 3 page