10,303 research outputs found

    Is the bulbus arteriosus of fish homologous to the mamalian intrapericardial thoracic arteries?

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    El resumen aparece en el Program & Abstracts of the 10th International Congress of Vertebrate Morphology, Barcelona 2013.Anatomical Record, Volume 296, Special Feature — 1: P-089.Two major findings have significantly improved our understanding of the embryology and evolution of the arterial pole of the vertebrate heart (APVH): 1) a new embryonic presumptive cardiac tissue, named second heart field (SHF), forms the myocardium of the outflow tract, and the walls of the ascending aorta (AA) and the pulmonary trunk (PT) in mammals and birds; 2) the bulbus arteriosus (BA), previously thought to be an actinopterygian apomorphy, is present in all basal Vertebrates, and probably derives from the SHF. We hypothesized that the intrapericardial portions of the AA and the PT of mammals are homologous to the BA of basal vertebrates. To test this, we performed 1) a literature review of the anatomy and embryology of the APVH; 2) novel anatomical, histomorphological, and embryological analyses of the APVH, comparing basal (Galeus atlanticus), with apical (Mus musculus and Mesocricetus auratus) vertrebrates. Evidence obtained: 1) Anatomically, BA, AA, and PT are muscular tubes into the pericardial cavity, which connect the distal myocardial outflow tracts with the aortic arch system. Coronary arteries run through or originate at these anatomical structures; 2) Histologically, BA, AA, and PT show an inner layer of endothelium covered by circumferentially oriented smooth muscle cells, collagen fibers, and lamellar elastin. The histomorphological differences between the BA and the ventral aorta parallel those between intrapericardial and extrapericardial great arteries; 3) Embryologically, BA, AA, and PT are composed of smooth muscle cells derived from the SHF. They show a similar mechanism of development: incorporation of SHF‐derived cells into the pericardial cavity, and distal‐to‐proximal differentiation into an elastogenic cell linage. In conclusion, anatomical, histological and embryological evidence supports the hypothesis that SHF is a developmental unit responsible for the formation of the APVH. The BA and the intrapericardial portions of the great arteries must be considered homologous structures.Proyecto P10-CTS-6068 (Junta de Andalucía); proyecto CGL-16417 (Ministerio de Ciencia e Innovación); Fondos FEDER

    Sons, Brothers and Relatives in the Entourages of the Roman Provincial Commanders during the Republic: A Characteristic Behaviour of the Roman Ruling Class

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    Durante la época de la República era una costumbre bien conocida que el cónsul o pretor destinado a una provincia se dotara de una serie de colaboradores y acompañantes que constituían la cohors o comitiva del imperator. Dicha comitiva solía componerse de personas vinculadas a los círculos sociales y particularmente familiares del mandatario en cuestión, siendo habitual encontrar en éstas a parientes, hermanos e incluso hijos de los mandos romanos. Aunque los autores clásicos no suelen conceder demasiada atención el papel que cumplían los hijos y parientes en el séquito de colaboradores de un mandatario provincial, su presencia habitual en estas comitivas indica que se trataba de un comportamiento característico y representativo de la clase política romana, cuyo interés no se hallaba sólo en contribuir a la promoción política y social de los implicados, sino en el hecho en sí de participar de unos hábitos distintivos y privativos de la nobilitas.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Banking Stability and Shadow banking: New Overview for the United States

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    This paper analyses commercial banking and shadow banking, with the intention of understanding different channels of instability that can occur through both types of banking for the United States. The work is pioneering a comprehensive vision of shadow banking and its interrelation with commercial banking. The results of the work are designed to encourage reflection on possible mediums to promote the stability of shadow banking, through new risk indicators. Finally, these indicators are tested using machine learning techniques

    The magazin Ressorgiment and the Catalan collectivity of Buenos Aires (1916-1946)

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    La revista Ressorgiment alcanzó la existencia más prolongada entre todas las que crearon los emigrantes catalanes en el exterior. También fue una de las más influyentes en los ambientes del nacionalismo catalán de América Latina, hasta su cierre en 1972. En el artículo se analizan en primer lugar las razones que explican la aparición de la revista en 1916 y su rápida difusión. A continuación se presenta el elenco de sus principales colaboradores y anunciantes, en Buenos Aires y Barcelona. También se consideran las relaciones de la revista con la colectividad catalana y española de la Argentina y con los principales centros catalanistas de América, como La Habana, Montevideo y Santiago de Chile. Un examen más detallado se dedica a las opiniones de la revista respecto de Cataluña, de España y de las comunidades emigrantes. Por último, el artículo se ocupa del impacto del exilio republicano sobre Ressorgiment.The magazine Ressorgiment reached the longest existence among all those created by the Catalan emigrants abroad. It was also one of the most influential in the environments of Catalan nationalism in Latin America, until its closure in 1972. The article analyzes the reasons that explain the appearance of the magazine in 1916 and its rapid diffusion. Then there is a brief presentation of its main collaborators and advertisers, in Buenos Aires and Barcelona. The relations with the Catalan and Spanish community of Argentina and with the main Catalanist centers of America, such as Havana, Montevideo and Santiago de Chile, are also considered. A more detailed examination is devoted to the opinions of the magazine regarding Catalonia, Spain and the emigrant communities. Finally, the article deals with the impact of republican exile on Ressorgiment

    Recommender Systems for Learning

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    Un área de aplicación de los sistemas recomendadores es la educación. Se han utilizado para recomendar contenidos educativos, compañeros de estudio, trayectos de aprendizaje, actividades y para concebir sistemas educativos adaptativos. Hasta el lanzamiento de este libro, todo ese conocimiento se encontraba diseminado en artículos de revistas y conferencias. El objetivo de esta obra es introducir brevemente la problemática y discutir una amplia variedad de temas en los que actualmente se investiga y que deberán enfrentar quienes tengan como meta construir Sistemas Recomendadores para Aprender. Sus autores son expertos en la temática, han organizado múltiples conferencias especializadas en el tema y han escrito un gran número de artículos. Se trata de un libro corto, organizado en cuatro capítulos

    Incidence and type of bicuspid aortic valve in two model species

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    Incidence and type of bicuspid aortic valve in two model species. MC Fernández 1,2, A López-García 1,2, MT Soto 1, AC Durán 1,2 and B Fernández 1,2. 1 Department of Animal Biology, Faculty of Science, University of Málaga, Spain. 2 Biomedical Research Institute of Málaga (IBIMA), University of Málaga, Spain. Bicuspid aortic valve (BAV) is the most frequent human congenital cardiac malformation, with an incidence of 1–2% worldwide. Two morphological types exist: type A (incidence 0.75–1.25%) and type B (incidence 0.25–0.5%), each with a distinct aetiology and natural history. Currently, ten animal models of BAV have been described in two different rodent species: one spontaneous Syrian hamster (Mesocricetus auratus) model of BAV type A and nine mutant laboratory mouse (Mus musculus) models of BAV type B. It remains to be elucidated whether the mutations leading to BAV in these models are typespecific or whether there are inter-specific differences regarding the type of BAV that hamsters, mice and humans may develop. To solve this issue, we have characterized the incidence and types of BAVs in four inbred, two outbred and two hybrid lines of Syrian hamsters (n=4,340) and in three inbred, three outbred and one hybrid lines of laboratory mice (n=1,661) by means of stereomicroscopy and scanning electron microscopy. In addition, we have reviewed and calculated the incidence and type of BAVs in the published papers dealing with this anomaly in mice. Our results indicate that the Syrian hamster develops BAVs type A and B including a variety of morphologies comparable to those of humans, whereas the mouse develops only BAVs type B with a short spectrum of valve morphologies. Thus, inter-specific differences between human and mouse aortic valves must be taken into consideration when studying valve disease in murine models. This work was supported by P10-CTS-6068.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. P10-CTS-6068

    Resistance to the SDHI fungicides boscalid and fluopyram in Podosphaera xanthii from commercial cucurbit fields in Spain

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    Powdery mildew elicited by Podosphaera xanthii is a devastating disease of cucurbits worldwide and one of the most important diseases affecting these crops in Spain. Application of fungicides is the main control practice for managing P. xanthii; however, isolates resistant to multiple classes of site-specific fungicides have been recently reported in the Spanish cucurbit powdery mildew population. Succinate dehydrogenase inhibitors (SDHIs) constitute a relatively novel class of fungicides registered for powdery mildew control representing new alternatives for cucurbit growers. In the present study, 30 P. xanthii isolates were used to determine the effective concentration that reduces mycelial growth by 50% (EC50) to boscalid and fluopyram. The present study was also conducted to obtain discriminatory doses to monitor SDHI fungicide resistance in 180 P. xanthii isolates collected from several commercial cucurbit fields in Spain during 2017-2018. Three SDHI resistance patterns were observed in our population, which include patterns I (resistance to boscalid), II (resistance to fluopyram), and III (resistance to boscalid and fluopyram). The amino acid changes associated with these resistance patterns in the Sdh protein were also examined. Based on our results, SDHI fungicides are good alternatives for cucurbit powdery mildew control, although they should be applied with caution.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

    Tunable directional emission and collective dissipation with quantum metasurfaces

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    Subwavelength atomic arrays, recently labeled as quantum metamaterials, have emerged as an exciting platform for obtaining novel quantum optical phenomena. The strong interference effects in these systems generate subradiant excitations that propagate through the atomic array with very long lifetimes. Here, we demonstrate that one can harness these excitations to obtain tunable directional emission patterns and collective dissipative couplings when placing judiciously additional atoms nearby the atomic array. For doing that, we first characterize the optimal array geometry to obtain directional emission patterns. Then, we characterize the best atomic positions to couple efficiently to the subradiant metasurface excitations, and provide several improvement strategies based on entangled atomic clusters or bilayers. Afterwards, we also show how the directionality of the emission pattern can be controlled through the relative dipole orientation between the auxiliary atoms and the one of the array. Finally, we benchmark how these directional emission patterns translate into to collective, anisotropic dissipative couplings between the auxiliary atoms by studying the lifetime modification of atomic entangled states.Comment: 16 pages, 11 figure
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