603 research outputs found
Arabidopsis thaliana is able to sense tomato Systemin promoting defense against fungal pathogens
Pòster presentat al Symposium on Small Molecules in Plant Research: Chemistry and Biology Come Together (Valencia, Spain, 10-11 December 2019).Systemin is a small tomato peptide that regulates the plant response against herbivores and pathogenic fungi. It is released from a larger precursor upon wounding or pathogen attack and binds to a membrane receptor of the adjacent cell inducing a cascade of plant defences, including JA-related responses, that lead to the accumulation of protease inhibitors in local and systemic tissue.
Although the tomato Systemin has been the focus of many recent studies, very little is known about the perception and function of Systemin in heterologous species
DDIExtractor: A Web-based Java Tool for Extracting Drug-Drug Interactions from Biomedical Texts
Proceeding of: 16th International Conference on Applications of Natural Language to Information Systems, NLDB 201. Took place 2011, June 28-30, in Alicante, Spain. The event Web site is http://gplsi.dlsi.ua.es/congresos/nldb11/A drug-drug interaction (DDIs) occurs when one drug influences the level or activity of another drug. The detection of DDIs is an important research area in patient safety since these interactions can become very dangerous and increase health care costs. Although there are several databases and web tools providing information on DDIs to patients and health-care professionals, these resources are not comprehensive because many DDIs are only reported in the biomedical literature. This paper presents the first tool for detecting drug-drug interactions from biomedical texts called DDIExtractor. The tool allows users to search by keywords in the Medline 2010 baseline database and then detect drugs and DDIs in any retrieved document.This work is supported by the projects MA2VICMR
(S2009/TIC-1542) and MULTIMEDICA (TIN2010-20644-C03-01).Publicad
Luminescence from growth topographic features in GaN : Si films
Cathodoluminescence (CL) in the scanning electron microscope is used to investigate the nature of defects responsible for the luminescence associated with round and hexagonal-like topographic features of GaN:Si films. Round hillocks of the size of a few microns, which sometimes have a nanopipe related central hole, do not influence the luminescence emission of the film. Hillocks with sizes of several tens of microns show a marked CL contrast at the center and at the border. The origin of the observed contrast is attributed to a growth induced inhomogeneous distribution of point defects and impurities. Radiation with the electron beam of the scanning microscope causes a decrease of the CL intensity without spectral changes
The 1st DDIExtraction-2011 Challenge Task: Extraction of Drug-Drug Interactions from Biomedical Texts
Proceeding at: The 1st DDIExtraction-2011 Challenge Task: Extraction of Drug-Drug Interactions from Biomedical Texts. Took place September, 2011, in Huelva (Spain).We present an evaluation task designed to provide a framework for comparing different approaches to extracting drug-drug interactions from biomedical texts.We define the task, describe the training/test data, list the participating systems and discuss their results. There were 10 teams who submitted a total of 40 runs.This study was funded by the projects MA2VICMR (S2009/TIC-1542) and MULTIMEDICA (TIN2010-20644-C03-01). The organizers are particularly grate-ful to all participants who contributed to detect annotation errors in the corpus.Publicad
Combining Syntactic Information and Domain-Specific Lexical Patterns to Extract Drug-Drug Interactions from Biomedical Texts
Proceeding at: 19th ACM International Conference on Information and Knowdledge Management. Took place October, 26-30 2010, in Toronto, Canada. The event Web site is http://www.yorku.ca/cikm10/A drug-drug interaction (DDI) occurs when one drug influences the level or activity of another drug. The increasing volume of the scientific literature overwhelms health care professionals trying to be kept up-to-date with all published studies on DDI. Information Extraction (IE) techniques can provide an interesting way of reducing the time spent by health care professionals on reviewing the literature. Nevertheless, no approach has been carried out to extract DDI from texts. To the best of our knowledge, this work proposes the first integral solution for the automatic extraction of DDI from biomedical texts.This work has been partially supported by the Spanish research projects: MA2VICMR consortium (S2009/TIC-1542, www.mavir.net), a network of excellence funded by the Madrid Regional Government and TIN2007-67407-C03-01 (BRAVO: Advanced Multimodal and Multilingual Question Answering).Publicad
Propuesta de un nuevo modelo teĂłrico para la EnfermerĂa del Trabajo adaptado al entorno español
EnfermerĂ
MIRACLE’s hybrid approach to bilingual and monolingual Information Retrieval
The main goal of the bilingual and monolingual participation of the MIRACLE team at CLEF 2004 was testing the effect of combination approaches to information retrieval. The starting point is a set of basic components: stemming, transformation, filtering, generation of n-grams, weighting and relevance feedback. Some of these basic components are used in different combinations and order of application for document indexing and for query processing. Besides this, a second order combination is done, mainly by averaging or by selective combination of the documents retrieved by different approaches for a particular query
Using a shallow linguistic kernel for drug-drug interaction extraction
A drug–drug interaction (DDI) occurs when one drug influences the level or activity of another drug. Information Extraction (IE) techniques can provide health care professionals with an interesting way to reduce time spent reviewing the literature for potential drug–drug interactions. Nevertheless, no approach has been proposed to the problem of extracting DDIs in biomedical texts. In this article, we study whether a machine learning-based method is appropriate for DDI extraction in biomedical texts and whether the results provided are superior to those obtained from our previously proposed pattern-based approach [1]. The method proposed here for DDI extraction is based on a supervised machine learning technique, more specifically, the shallow linguistic kernel proposed in Giuliano et al. (2006) [2]. Since no benchmark corpus was available to evaluate our approach to DDI extraction, we created the first such corpus, DrugDDI, annotated with 3169 DDIs. We performed several experiments varying the configuration parameters of the shallow linguistic kernel. The model that maximizes the F-measure was evaluated on the test data of the DrugDDI corpus, achieving a precision of 51.03%, a recall of 72.82% and an F-measure of 60.01%.
To the best of our knowledge, this work has proposed the first full solution for the automatic extraction of DDIs from biomedical texts. Our study confirms that the shallow linguistic kernel outperforms our previous pattern-based approach. Additionally, it is our hope that the DrugDDI corpus will allow researchers to explore new solutions to the DDI extraction problem.This study was funded by the Projects MA2VICMR (S2009/TIC-1542) and MULTIMEDICA (TIN2010-20644-C03-01).Publicad
Effect of laser irradiation on the luminescence of Mg and Si-doped GaN films
Pulsed laser treatments have been performed in GaN samples of both n- and p-type conductivity. The laser induced changes have been monitored by emissive mode and cathodoluminescence (CL) in a scanning electron microscope. Emissive mode observations indicate a moderate laser induced recrystallization. The luminescent emission has been characterized in both types of samples, GaN:Si and GaN:Mg. Whereas the evolution of CL in the Si doped samples could be explained by the occurrence of laser induced annealing, the luminescent behavior of the Mg doped samples upon irradiation seems to be more complex and a strong relation with the compensation or Mg activation is suggested. Several luminescence bands with maxima ranging from 3.3 to 2.7 eV and their dependence on irradiation conditions have been studied
Growth and luminescence properties of micro- and nanoneedles in sintered CdSe
Sintering CdSe powder under argon flow at temperatures in the range 800-900 degreesC produces the formation of needles on the sample surface. Bundles of parallel needles of a diameter of about 50 nm give rise to a domain-like appearance in the sample. In addition, rods and needles with a wide range of dimensions up to several microns appear distributed in the surface. The influence of ball milling of the starting powder on the formation of the needles is investigated. Cathodoluminescence in the scanning electron microscope has been used to characterize the sintered samples
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