5,063 research outputs found

    Mechanical Analysis of WEST divertor support plate

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    The Tore Supra tokamak is being transformed in an x-point divertor fusion device in the frame of the WEST (W-for tungsten-Environment in Steady-state Tokamak) project, launched in support to the ITER tungsten divertor strategy. The WEST project aims to test W monoblock Plasma Facing Units (PFU) under long plasma discharge (up to 1000s), with thermal loads of the same magnitude as those expected for ITER. Therefore the divertor is a key component of the WEST project, and so is its support structure, which has to handle strong mechanical loads. The WEST upper and lower divertor are made of 12 30° sectors, each one composed of 38 PFU that can be made of tungsten, CuCrZr or graphite. A generic 316L stainless steel 30° conic support plate is used to hold the 38 PFU together, regardless of their material. The PFUs are fixed on the support plate thanks to 152 Xm19 stainless steel fixing elements (4 per PFU), and in each of this fixing element an Aluminium-Nickel-Bronze alloy (Al-Ni-Br) pin is engaged in a slotted hole, in order to allow thermal expansion in the length direction of the PFU. The support plate is fixed on the divertor coil casing thanks to 10 M10 screws. Mechanicals loads which act on the PFUs are transmitted to the support plate through the fixing elements. These loads are due to Vertical Displacement Event (VDE), disruptions and thermal expansion of the PFU. First the different load cases, PFU configurations and scenario are presented. Then an ANSYS plastic mechanical simulation is performed in order to validate the number of cycles of the support plate for each scenario: 30 000 cycles in steady-state and 3000 cycles in VDE. Finally reactions forces from the previous ANSYS simulation are used in order to calculate the stress in the M10 screws

    Epidemiology of biliary tract cancers: an update

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    Background: Biliary tract cancer (BTC) is a rare cancer in Europe and North America, characterized by wide geographic variation, with high incidence in some areas of Latin America and Asia. Materials and methods: BTC mortality and incidence have been updated according to recent data, using joinpoint regression analysis. Results: Since the 1980s, decreasing trends in BTC mortality rates (age-standardized, world standard population) were observed in the European Union as a whole, in Australia, Canada, Hong Kong, Israel, New Zealand, and the United States, and high-risk countries such as Japan and Venezuela. Joinpoint regression analysis indicates that decreasing trends were more favorable over recent calendar periods. High-mortality rates are, however, still evident in central and eastern Europe (4-5/100 000 women), Japan (4/100 000 women), and Chile (16.6/100 000 women). Incidence rates identified other high-risk areas in India (8.5/100 000 women), Korea (5.6/100 000 women), and Shanghai, China (5.2/100 000 women). Conclusions: The decreasing BTC mortality trends essentially reflect more widespread and earlier adoption of cholecystectomy in several countries, since gallstones are the major risk factor for BTC. There are, however, high-risk areas, mainly from South America and India, where access to gall-bladder surgery remains inadequat

    Novel mechanism of photoinduced reversible phase transitions in molecule-based magnets

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    A novel microscopic mechanism of bi-directional structural changes is proposed for the photo-induced magnetic phase transition in Co-Fe Prussian blue analogues on the basis of ab initio quantum chemical cluster calculations. It is shown that the local potential energies of various spin states of Co are sensitive to the number of nearest neighbor Fe vacancies. As a result, the forward and backward structural changes are most readily initiated by excitation of different local regions by different photons. This mechanism suggests an effective strategy to realize photoinduced reversible phase transitions in a general system consisting of two local components.Comment: 4 pages, LaTex, 3 figures, to appear in Phys. Rev. Let

    Determinants of Acceptance of Cervical Cancer Screening in Dar es Salaam, Tanzania.

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    To describe how demographic characteristics and knowledge of cervical cancer influence screening acceptance among women living in Dar es Salaam, Tanzania. Multistage cluster sampling was carried out in 45 randomly selected streets in Dar es Salaam. Women between the ages of 25-59 who lived in the sampled streets were invited to a cervical cancer screening; 804 women accepted and 313 rejected the invitation. Information on demographic characteristics and knowledge of cervical cancer were obtained through structured questionnaire interviews. Women aged 35-44 and women aged 45-59 had increased ORs of 3.52 and 7.09, respectively, for accepting screening. Increased accepting rates were also found among single women (OR 2.43) and among women who had attended primary or secondary school (ORs of 1.81 and 1.94). Women who had 0-2 children were also more prone to accept screening in comparison with women who had five or more children (OR 3.21). Finally, knowledge of cervical cancer and awareness of the existing screening program were also associated with increased acceptance rates (ORs of 5.90 and 4.20). There are identifiable subgroups where cervical cancer screening can be increased in Dar es Salaam. Special attention should be paid to women of low education and women of high parity. In addition, knowledge and awareness raising campaigns that goes hand in hand with culturally acceptable screening services will likely lead to an increased uptake of cervical cancer screening

    Sequencing and Welding of Molecular Single-Crystal Optical Waveguides

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    Molecular crystals are promising anisotropic optical transducing media for next-generation optoelectronic microdevices that will be capable of secure transduction of information and impervious to external electromagnetic interference. However, their full potential has not been explored yet due to their poor processability, low mechanical compliance, pronounced brittleness and high proneness to cracking that often result in irrecoverable damage. These issues are detrimental to their ability to transduce light. Here, a novel strategy is presented based on 3D epitaxial crystal growth of organic/inorganic crystals based on charge-assisted hydrogen bonds that can be used to efficiently weld broken molecular single-crystalline optical waveguides and restore their light-transducing capability. This approach can also be applied to prepare asymmetric multidomain crystalline heterostructures starting from isostructural molecular tectons, resulting in novel opto/electro/mechanical functionalities in the hybrid materials. It also removes an important obstacle toward wider application of molecular crystals in the next-generation optoelectronics

    Electron scattering from molecules and molecular aggregates of biological relevance

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    In this Topical Review we survey the current state of the art in the study of low energy electron collisions with biologically relevant molecules and molecular clusters. We briefly describe the methods and techniques used in the investigation of these processes and summarise the results obtained so far for DNA constituents and their model compounds, amino acids, peptides and other biomolecules. The applications of the data obtained is briefly described as well as future required developments
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