On a Question of Haskell P. Rosenthal Concerning a Characterization of c_0 and ℓ_p

The following property of a normalized basis in a Banach space is considered: any normalized block sequence of the basis has a subsequence equivalent to the basis. Under uniformity or other natural assumptions, a basis with this property is equivalent to the unit vector basis of c_0 or ℓ_p. An analogous problem concerning spreading models is also addressed

Screening for Mutations of 21-Hydroxylase Gene in Hungarian Patients with Congenital Adrenal Hyperplasia

Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders, causing impaired secretion of cortisol and aldosterone from the adrenal cortex, with subsequent overproduction of adrenal androgens. The most common enzyme defect causing CAH is steroid 21-hydroxylase deficiency. To determine the mutational spectrum in the Hungarian CAH population, the CYP21 active gene was analyzed using PCR. A total of 297 Hungarian patients with 21-hydroxylase deficiency are registered in the 2nd Department of Pediatrics, Budapest, Hungary, and their clinical status was evaluated. Blood samples for CYP21 genotype determination could be obtained from 167 patients (representing 306 unrelated chromosomes and 56.2% of the total group of patients). Eight of the most common mutations were screened [In2 (intron 2 splice mutation), I172N, Del (Del: apparents large gene conversion), Q318X, R356W, 1761Tins, ClusterE6, V281L] using allele-specific amplification. The most frequent mutation in the Hungarian CAH population was found to be In2. Our results have shown a good genotype/phenotype correlation in case of most mutations; the In2 mutation is associated mostly with the severe form of the disease, whereas I172N was expressed in a wide spectrum of phenotypes

Peculiarities of ball-milling induced crystalline-amorphous transformation in Cu-Zr-Al-Ni-Ti alloys

An amorphization process in (Cu49Zr45-xAl6+x)100-y-zNiyTiz (x = 1, y, z = 0; 5; 10) induced by ball-milling is reported in the present work. The aim was investigation of the effect of Ni and Ti addition to Cu49Zr45Al6 and Cu49Zr44Al7 based alloys as well as type of initial phases on the amorphization processes. Also the milling time sufficient for obtaining fully amorphous state was determined. The entire milling process lasted 25 h. Drastic structural changes were observed in each alloy after first 5 h of milling. In most cases, after 15 h of milling the powders had fully amorphous structure according to XRD except for those ones, where TEM revealed a few nanosized crystalline particles in the amorphous matrix. In (Cu49Zr45Al6)80Ni10Ti10 alloy the amorphization process took place after 12 h of milling and the amorphous state was stable up to 25 h of milling. In the case of (Cu49Zr44Al7)80Ni10Ti10 alloy the powders have fully amorphous structure between 12 h and 15 h of milling. © 2015 Elsevier Ltd. All rights reserved

Microstructure evolution in CuZrAl alloys during ball-milling

Abstract The microstructure evolution during mechanical milling was studied in the CuZrAl system. The compositions lay on the two liquidus surfaces indicating different solidification processes in the three alloys. Cu(55 − x)Zr(35 + x)Al10 (x = 0; 5; 10 at.%) master alloys were produced by arc melting. After identification of the phases, the master alloys were milled for 25 h and amorphous/crystalline powders were synthesized. The master alloys contained Al21Cu28Zr51, AlCu2Zr, CuZr and traces of Cu10Zr7 phases in different volume fractions. The optimal milling time was determined to be 15 h based on the results of X-ray diffractometry (XRD) and differential scanning calorimetry (DSC) examinations. The 5 h milled powder contained CuZr and Al21Cu28Zr51 phases, which diminished due to further milling resulting in amorphous matrix composite with nanosized Al21Cu28Zr51 phase. The thermal stability of the samples was investigated by DSC. The peak temperatures of the first crystallization process of the as-milled powders shifted as function of milling time and polynomial curves were fitted to the measured points

Specific detection and quantitation of bovine IgG in bioreactor derived mouse mAb preparations

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A psychoanalytic concept illustrated: Will, must, may, can — revisiting the survival function of primitive omnipotence

The author explores the linear thread connecting the theory of Freud and Klein, in terms of the central significance of the duality of the life and death instinct and the capacity of the ego to tolerate contact with internal and external reality. Theoretical questions raised by later authors, informed by clinical work with children who have suffered deprivation and trauma in infancy, are then considered. Theoretical ideas are illustrated with reference to observational material of a little boy who suffered deprivation and trauma in infancy. He was first observed in the middle of his first year of life while he was living in foster care, and then later at the age of two years and three months, when he had been living with his adoptive parents for more than a year