A novel method for validating multi-classifiers. A case study for ICF-based health status classification

In this paper, we propose a novel method for the validation of a multi-classification model according to the intended use and aim of a device for health status classification and the clinical needs of the practitioners involved

A Web Service Composition Method Based on OpenAPI Semantic Annotations

Automatic Web service composition is a research direction aimed to improve the process of aggregating multiple Web services to create some new, specific functionality. The use of semantics is required as the proper semantic model with annotation standards is enabling the automation of reasoning required to solve non-trivial cases. Most previous models are limited in describing service parameters as concepts of a simple hierarchy. Our proposed method is increasing the expressiveness at the parameter level, using concept properties that define attributes expressed by name and type. Concept properties are inherited. The paper also describes how parameters are matched to create, in an automatic manner, valid compositions. Additionally, the composition algorithm is practically used on descriptions of Web services implemented by REST APIs expressed by OpenAPI specifications. Our proposal uses knowledge models (ontologies) to enhance these OpenAPI constructs with JSON-LD semantic annotations in order to obtain better compositions for involved services. We also propose an adjusted composition algorithm that extends the semantic knowledge defined by our model.Comment: International Conference on e-Business Engineering (ICEBE) 9 page

Prikaz znanja u internetu stvari: semantičko modeliranje i njegove primjene

Semantic modelling provides a potential basis for interoperating among different systems and applications in the Internet of Things (IoT). However, current work has mostly focused on IoT resource management while not on the access and utilisation of information generated by the “Things”. We present the design of a comprehensive and lightweight semantic description model for knowledge representation in the IoT domain. The design follows the widely recognised best practices in knowledge engineering and ontology modelling. Users are allowed to extend the model by linking to external ontologies, knowledge bases or existing linked data. Scalable access to IoT services and resources is achieved through a distributed, semantic storage design. The usefulness of the model is also illustrated through an IoT service discovery method.Semantičko modeliranje pruža potencijalnu osnovu za me.udjelovanje različitih sustava i aplikacija unutar interneta stvari (IoT). Međutim, postojeći radovi uglavnom su fokusirani na upravljanje IoT resursima, ali ne i pristupu i korištenju informacija koje generira “stvar”. Predstavljamo projektiranje sveobuhvatnog i laganog semantičkog opisnog modela za prikaz znanja u IoT domeni. Projektiranje slijedi široko-priznate najbolje običaje u inženjerstvu znanja i ontološkom modeliranju. Korisnicima se dopušta proširenje modela povezivanjem na eksterne ontologije, baze znanja ili postoje će povezane podatke. Skalabilni pristup IoT uslugama i resursima postiže se kroz distribuirano, semantičko projektiranje pohrane. Upotrebljivost modela tako.er je ilustrirana kroz metodu pronalaska IoT usluga

Activating Generalized Fuzzy Implications from Galois Connections

This paper deals with the relation between fuzzy implications and Galois connections, trying to raise the awareness that the fuzzy implications are indispensable to generalise Formal Concept Analysis. The concrete goal of the paper is to make evident that Galois connections, which are at the heart of some of the generalizations of Formal Concept Analysis, can be interpreted as fuzzy incidents. Thus knowledge processing, discovery, exploration and visualization as well as data mining are new research areas for fuzzy implications as they are areas where Formal Concept Analysis has a niche.F.J. Valverde-Albacete—was partially supported by EU FP7 project LiMoSINe, (contract 288024). C. Peláez-Moreno—was partially supported by the Spanish Government-CICYT project 2011-268007/TEC.Publicad

A mouse informatics platform for phenotypic and translational discovery

The International Mouse Phenotyping Consortium (IMPC) is providing the world’s first functional catalogue of a mammalian genome by characterising a knockout mouse strain for every gene. A robust and highly structured informatics platform has been developed to systematically collate, analyse and disseminate the data produced by the IMPC. As the first phase of the project, in which 5000 new knockout strains are being broadly phenotyped, nears completion, the informatics platform is extending and adapting to support the increasing volume and complexity of the data produced as well as addressing a large volume of users and emerging user groups. An intuitive interface helps researchers explore IMPC data by giving overviews and the ability to find and visualise data that support a phenotype assertion. Dedicated disease pages allow researchers to find new mouse models of human diseases, and novel viewers provide high-resolution images of embryonic and adult dysmorphologies. With each monthly release, the informatics platform will continue to evolve to support the increased data volume and to maintain its position as the primary route of access to IMPC data and as an invaluable resource for clinical and non-clinical researchers

Nat Genet

The function of the majority of genes in the mouse and human genomes remains unknown. The mouse embryonic stem cell knockout resource provides a basis for the characterization of relationships between genes and phenotypes. The EUMODIC consortium developed and validated robust methodologies for the broad-based phenotyping of knockouts through a pipeline comprising 20 disease-oriented platforms. We developed new statistical methods for pipeline design and data analysis aimed at detecting reproducible phenotypes with high power. We acquired phenotype data from 449 mutant alleles, representing 320 unique genes, of which half had no previous functional annotation. We captured data from over 27,000 mice, finding that 83% of the mutant lines are phenodeviant, with 65% demonstrating pleiotropy. Surprisingly, we found significant differences in phenotype annotation according to zygosity. New phenotypes were uncovered for many genes with previously unknown function, providing a powerful basis for hypothesis generation and further investigation in diverse systems.Comment in : Genetic differential calculus. [Nat Genet. 2015] Comment in : Scaling up phenotyping studies. [Nat Biotechnol. 2015

Agent-assisted Tagging aimed at Folkonomy-Based Information Retrieval

The wide diffusion of community tagging sites and related folksonomies has made the knowledge discovery and retrieval still much more urgent topic. If tagging systems allow users to add freely keywords to web resources, clicking on a tag has the side effect of a tag-based query, since enables the users to explore related content. The collective knowledge expressed though user-annotated data has a big potential, but needs to be filtered in a digest form so that the search result better reflects the users' preferences and actual aims. Starting from these considerations, our work presents an agent-based approach for a scalable semi-automatic generation of annotation tags, personalized on each user's preferences and tastes. Primary is the role of agents which assist users in the tagging activities as well as the retrieval of resources related to their interest. A user-friendly interface proposes an integrated one-shot view for interacting with a tagging system

Patterns for visual management in industry 4.0

The technologies of Industry 4.0 provide an opportunity to improve the effectiveness of Visual Management in manufacturing. The opportunity of improvement is twofold. From one side, Visual Management theory and practice can inspire the design of new software tools suitable for Industry 4.0; on the other side, the technology of Industry 4.0 can be used to increase the effectiveness of visual software tools. The paper first explores how the theoretical result on Visual Management can be used as a guideline to improve human‐computer interaction, then a methodology is proposed for the design of visual patterns for manufacturing. Four visual patterns are presented that contribute to the solution of problems frequently encountered in discrete manufacturing industries; these patterns help to solve planning and control problems thus providing support to various management functions. Positive implications of this research concern people engagement and empowerment as well as improved problem solving, decision‐making and management of manufacturing processes