What Factors Predict the Adoption of Type 2 Diabetes Patients to Wearable Activity Trackers—Application of Diffusion of Innovation Theory

Background: Globally, diabetes has brought an enormous burden to public health resources, and the situation of disease burden caused by diabetes in China is especially severe. China is currently facing the dual threat of aging and diabetes, and wearable activity trackers could promote elderly diabetic patients' physical activity levels and help them to manage blood glucose control. Therefore, examining the influencing factors of elderly patients' adoption intention is critical as wearing adoption determines actual wearing behaviors.Objective: This study aims to explore the predicting factors of Chinese elderly type 2 diabetic patients' adoption intention to wearable activity trackers and their actual wearing behavior, using diffusion of innovation theory as the theoretical framework. We hope to provide insights into future interventions using wearable activity trackers as tools to improve the outcome of patients.Methods: Wearable activity trackers were freely distributed to type 2 diabetic patients in Beijing, China. A questionnaire survey was conducted to examine predicting factors of adoption intention after a week's try-on. Actual wearing behavior for 3-month was obtained from the exclusive cloud. Data were analyzed with structural equation modeling.Results: A total of 725 patients completed the questionnaire. Patients had a mean age of 60.3 ± 7.6 years old and the educational level was generally lower. The results indicated that observability was the primary influencing factor of patients' adoption intention (β = 0.775, P < 0.001). Relative advantage (β = 0.182, P = 0.014) and perceived social image (β = 0.080, P = 0.039) also had a positive influence while perceived risk (β = −0.148, P < 0.001) exerted a negative influence. In addition, results showed that the more intention led to the better actual wearing behavior (β = 0.127, P = 0.003). Observability (β = 0.103, P = 0.005), perceived ease (β = 0.085, P = 0.004), and relative advantage (β = 0.041, P = 0.009) also indirectly influenced the wearing behavior.Conclusion: The intentions of Chinese elderly type 2 diabetic patients to wearable activity trackers directly influenced the actual wearing behavior. In addition, their adoption intention to wearable activity trackers was mainly influenced by observability, perceived ease to use, relative advantage, perceived risk, and social image

Spectral self-adaptive absorber/emitter for harvesting energy from the sun and outer space

The sun (~6000 K) and outer space (~3 K) are the original heat source and sink for human beings on Earth. The energy applications of absorbing solar irradiation and harvesting the coldness of outer space for energy utilization have attracted considerable interest from researchers. However, combining these two functions in a static device for continuous energy harvesting is unachievable due to the intrinsic infrared spectral conflict. In this study, we developed spectral self-adaptive absorber/emitter (SSA/E) for daytime photothermal and nighttime radiative sky cooling modes depending on the phase transition of the vanadium dioxide coated layer. A 24-hour day-night test showed that the fabricated SSA/E has continuous energy harvesting ability and improved overall energy utilization performance, thus showing remarkable potential in future energy applications.Comment: 15 pages, 4 figure

Factors associated with distant metastasis in pediatric thyroid cancer: evaluation of the SEER database

Objectives: Controversies regarding factors associated with distant metastasis in pediatric thyroid cancer remain among the scientific community. The aim of this study was to investigate factors influencing distant metastasis in pediatric thyroid cancer. Methods: We reviewed 1376 patients (aged 2 to 18 years) with thyroid cancer treated between 2003 and 2014. Data collected and analyzed included sex, race, age at diagnosis, year of diagnosis, pathological type, number of tumor foci, tumor extension, T-stage, N-stage, surgical procedure and radiation. Univariate and multivariate analyses were conducted to evaluate factors influencing distant metastasis of pediatric thyroid cancer. Results: In the univariate analysis, factors influencing distant metastasis of thyroid cancer were age at diagnosis (P 0.05). Furthermore, according to chi-squared test, younger pediatric thyroid cancer patients with higher T- and N-stages are more likely to have distant metastasis. Conclusion: Age at diagnosis, T-stage and N-stage influence distant metastasis of thyroid cancer patients aged 2 to 18 years; accordingly, more radical treatments may need to be used for patients with those risk elements

Particle growth with photochemical age from new particle formation to haze in the winter of Beijing, China

Secondary aerosol formation in the aging process of primary emission is the main reason for haze pollution in eastern China. Pollution evolution with photochemical age was studied for the first time at a comprehensive field observation station during winter in Beijing. The photochemical age was used as an estimate of the time scale attributed to the aging process and was estimated from the ratio of toluene to benzene in this study. A low photochemical age indicates a fresh emission. The photochemical age of air masses during new particle formation (NPF) days was lower than that on haze days. In general, the strongest NPF events, along with a peak of the formation rate of 1.5 nm(J(1.5)) and 3 nmparticles (J(3)), were observed when the photochemical age was between 12 and 24 h while rarely took place with photochemical ages less than 12 h. When photochemical age was larger than 48 h, haze occurred and NPF was suppressed. The sources and sinks of nanoparticles had distinct relation with the photochemical age. Our results show that the condensation sink (CS) showed a valley with photochemical ages ranging from 12 to 24 h, while H2SO4 concentration showed no obvious trend with the photochemical age. The high concentrations of precursor vapours within an air mass lead to persistent nucleation with photochemical age ranging from 12 to 48 h in winter. Coincidently, the fast increase of PM2.5 mass was also observed during this range of photochemical age. Noteworthy, CS increased with the photochemical age on NPF days only, which is the likely reason for the observation that the PM2.5 mass increased faster with photochemical age on NPF days compared with other days. The evolution of particles with the photochemical age provides new insights into understanding how particles originating from NPF transform to haze pollution. (C) 2020 Elsevier B.V. All rights reserved.Peer reviewe

Five-Year Analysis of Lightning Activities in Different Climatic Regions of Sichuan Province, China

Sichuan is a high-incidence area of thunderstorm activity in China. Based on the data of the total lightning location system from 2018 to 2022, the total lightning, cloud-to-ground (CG) lightning, and intracloud (IC) lightning activity regularity for the Sichuan province (SC) and its three climate subregions: Sichuan Basin (SB), Panxi district (PD), and West Sichuan Plateau (WSP) are analyzed, and the influences of different climate and topography conditions on lightning activities are also discussed. The results show that (1) for the whole province, the annual mean value of total lightning is about 850 thousand. The SB has the most lightning occurrences, and the WSP has the largest IC and +CG proportion. The southwest of PD, the north-center of PD, and the southeast of SB are the three high-value centers of lightning density. (2) For SB, the better thermodynamic and moisture conditions account for the most lightning occurrences. For PD, the lightning distribution is attributed to the joint effect of specific meteorological conditions and mountainous topography. For WSP, the convections are weak and shallow, which lead to high IC and +CG proportion. (3) The IC lightning mainly occurs below 12 km, and the IC height is much lower on WSP. The spatial and seasonal variation of IC height corresponds well to the cloud base height (CBH) and cloud top height (CTH). (4) The seasonal lightning frequency distribution in the three regions is similar, but the diurnal variation is quite different. The lightning activity mainly occurs between 1400 and 2200 LT on WSP but shows obvious nocturnal in SB. (5) Most CG intensity concentrates in the range below 50 kA, and IC concentrates in the range below 75 kA

Myricanol Induces Apoptotic Cell Death and Anti-Tumor Activity in Non-Small Cell Lung Carcinoma in Vivo

This study explored the inhibiting effect and mechanism of myricanol on lung adenocarcinoma A549 xenografts in nude mice. Forty nude mice with subcutaneous A549 xenografts were randomly divided into five groups: high-dose myricanol (40 mg/kg body weight) group; middle-dose myricanol (20 mg/kg body weight) group; low-dose myricanol (10 mg/kg body weight) group; polyethylene glycol 400 vehicle group (1 mL/kg); and tumor model group. Nude mice were sacrificed after 14 days of treatment and the tumor inhibition rate (TIR, %) was then calculated. The relative mRNA expression levels of Bax, Bcl-2, VEGF, HIF-1α, and survivin in the tumor tissues were determined by real-time PCR. TUNEL assay was applied to determine cellular apoptosis, while IHC test was performed to detect the protein expression levels of Bax, Bcl-2, VEGF, HIF-1α, and survivin. The TIR of the three myricanol-treated groups ranged from 14.9% to 38.5%. The IHC results showed that the protein expression of Bcl-2, VEGF, HIF-1α, and survivin were consistently downregulated, whereas that of Bax was upregulated after myricanol treatment. Myricanol also significantly upregulated the mRNA expression of Bax and downregulated that of Bcl-2, VEGF, HIF-1α, and survivin in a dose-dependent manner (p &lt; 0.05 to 0.001). These results are consistent with those of IHC. The TUNEL assay results indicated that apoptotic-positive cells significantly increased in the myricanol-treated tumor tissues compared with the cells of the vehicle control group (p &lt; 0.01 to 0.001). These data suggest that myricanol could significantly decelerate tumor growth in vivo by inducing apoptosis

Hydrogen storage properties of Nd5Mg41Ni alloy improved by GO

Due to the high activation energy required for the decomposition of Mg metal hydrides, it can be decomposed into magnesium and H2 when the external temperature reaches 350 °C. In this paper, Nd5Mg41Ni + x wt.% GO (x = 0–4) composites were obtained by planetary ball milling the alloy with GO for 10 h. The alloy has Nd5Mg41, NdMg3, NdMg12 and Mg2Ni phase, and the main phase is Nd5Mg41 phase. The time required for the alloy phase structure composite material to reach the maximum hydrogen desorption capacity of 95 % is 20, 23, 18, 17 and 18 min, and the calculated hydrogen desorption activation energy Ea values are 99.9, 98.1, 95.6, 89.9 and 95.7 kJ/mol H2, the ΔHde of the composites are 77.57, 76.40, 73.48, 70.77 and 81.2 kJ/mol H2, respectively. The alloy particles are embedded in the layered GO to form a special microstructure of the nanocrystalline GO embedded nanocrystalline alloy, which makes the composite material easier to adsorb hydrogen molecules and promotes the dissociation of hydrogen molecules and the diffusion of hydrogen atoms. However, the excessive addition of GO leads to excessive GO coating alloy particles, which hinders the diffusion of hydrogen atoms. The agglomeration of alloy particles leads to the increase of hydrogen desorption enthalpy of the alloy

Study on β-Ga₂O₃ Films Grown with Various VI/III Ratios by MOCVD

&#946;-Ga2O3 films were grown on sapphire (0001) substrates with various O/Ga (VI/III) ratios by metal organic chemical vapor deposition. The effects of VI/III ratio on growth rate, structural, morphological, and Raman properties of the films were systematically studied. By varying the VI/III ratio, the crystalline quality obviously changed. By decreasing the VI/III ratio from 66.9 &#215; 103 to 11.2 &#215; 103, the crystalline quality improved gradually, which was attributed to low nuclei density in the initial stage. However, crystalline quality degraded with further decrease of the VI/III ratio, which was attributed to excessive nucleation rate