Agresiones contra la mujer y los integrantes del grupo familiar

El trabajo de suficiencia profesional está referenciado principalmente a la problemática de proteger a la víctima de violencia familiar "Agresiones contra la mujer y los integrantes del grupo familiar" clarificando las ideas con teorías, jurisprudencia y el Derecho comparado, a fin de dar una solución a esta problemática jurídica, emitiendo nuestras conclusiones y recomendaciones con finalidad de generar un debate que permita mejorar nuestro trabajo y permita mejorar la administración de justicia en estos conflictos con la intervención del Estado y el respeto principal de los derechos fundamentales, establecidos en la Constitución Política del Estado.Trabajo de Suficiencia Profesiona

Openness, access, and governance in Asian "Network Societies" : developing an open governance index; final technical report

This ICT index measures the extent of civil society groups’ utilization of ICTs measured against the extent of the ‘openness’ of the social and political environment. In each country, Thailand, India, Pakistan and the Philippines, a team of researchers undertook activities to map national level indicators related to project objectives: a) to further understand democratic e-governance, particularly through developing the discourse of “Open E- Governance”; b) to develop policy on ICT and governance, and engage policy stakeholders directly around the notions of “Open Governance”; and c) to develop a concrete resource for citizens/individuals, groups/non-government organizations to engage policymakers on “Open E-Governance”

Gamificación y habilidades blandas en niños de preescolar: Una revisión sistemática

La gamificación en la actualidad se constituye como una potente estrategia pedagógica, utilizada en diferentes escenarios y niveles educativos, el cual permite que los niños desarrollen sus habilidades blandas como: la creatividad, trabajo en equipo, liderazgo, autonomía y toma de decisiones, además de aumentar su motivación y hacerles presentar un mayor interés en lo que están aprendiendo. El objetivo del presente estudio fue analizar los recientes planteamientos sobre la gamificación en artículos científicos de bases de datos de alto impacto y su influencia en el desarrollo de las habilidades blandas en estudiantes de preescolar. Es una tesis cualitativa, de tipo básica y de diseño no experimental, se analizaron 18 artículos científicos recopilados de una búsqueda sistemática en las bases de datos de Redalyc, Scielo, Scopus y Dialnet, las cuales cumplieron con los criterios de exclusión e inclusión. Se concluye que los niños que utilizan la gamificación como método de aprendizaje tienen más desarrolladas sus habilidades blandas, por ello es importante fortalecerlas desde temprana eda

A Variant of The Theorem of Friendship

With the help of graph theory and linear algebra can give a demonstration a variant of the theorem of friendshi

Monogenic variants in dystonia: an exome-wide sequencing study

Background Dystonia is a clinically and genetically heterogeneous condition that occurs in isolation (isolated dystonia), in combination with other movement disorders (combined dystonia), or in the context of multisymptomatic phenotypes (isolated or combined dystonia with other neurological involvement). However, our understanding of its aetiology is still incomplete. We aimed to elucidate the monogenic causes for the major clinical categories of dystonia. Methods For this exome-wide sequencing study, study participants were identified at 33 movement-disorder and neuropaediatric specialty centres in Austria, Czech Republic, France, Germany, Poland, Slovakia, and Switzerland. Each individual with dystonia was diagnosed in accordance with the dystonia consensus definition. Index cases were eligible for this study if they had no previous genetic diagnosis and no indication of an acquired cause of their illness. The second criterion was not applied to a subset of participants with a working clinical diagnosis of dystonic cerebral palsy. Genomic DNA was extracted from blood of participants and whole-exome sequenced. To find causative variants in known disorder-associated genes, all variants were filtered, and unreported variants were classified according to American College of Medical Genetics and Genomics guidelines. All considered variants were reviewed in expert round-table sessions to validate their clinical significance. Variants that survived filtering and interpretation procedures were defined as diagnostic variants. In the cases that went undiagnosed, candidate dystonia-causing genes were prioritised in a stepwise workflow. Findings We sequenced the exomes of 764 individuals with dystonia and 346 healthy parents who were recruited between June 1, 2015, and July 31, 2019. We identified causative or probable causative variants in 135 (19%) of 728 families, involving 78 distinct monogenic disorders. We observed a larger proportion of individuals with diagnostic variants in those with dystonia (either isolated or combined) with coexisting non-movement disorder-related neurological symptoms (100 [45%] of 222;excepting cases with evidence of perinatal brain injury) than in those with combined (19 [19%] of 98) or isolated (16 [4%] of 388) dystonia. Across all categories of dystonia, 104 (65%) of the 160 detected variants affected genes which are associated with neurodevelopmental disorders. We found diagnostic variants in 11 genes not previously linked to dystonia, and propose a predictive clinical score that could guide the implementation of exome sequencing in routine diagnostics. In cases without perinatal sentinel events, genomic alterations contributed substantively to the diagnosis of dystonic cerebral palsy. In 15 families, we delineated 12 candidate genes. These include IMPDH2, encoding a key purine biosynthetic enzyme, for which robust evidence existed for its involvement in a neurodevelopmental disorder with dystonia. We identified six variants in IMPDH2, collected from four independent cohorts, that were predicted to be deleterious de-novo variants and expected to result in deregulation of purine metabolism. Interpretation In this study, we have determined the role of monogenic variants across the range of dystonic disorders, providing guidance for the introduction of personalised care strategies and fostering follow-up pathophysiological explorations

Racial differences in systemic sclerosis disease presentation: a European Scleroderma Trials and Research group study

Objectives. Racial factors play a significant role in SSc. We evaluated differences in SSc presentations between white patients (WP), Asian patients (AP) and black patients (BP) and analysed the effects of geographical locations.Methods. SSc characteristics of patients from the EUSTAR cohort were cross-sectionally compared across racial groups using survival and multiple logistic regression analyses.Results. The study included 9162 WP, 341 AP and 181 BP. AP developed the first non-RP feature faster than WP but slower than BP. AP were less frequently anti-centromere (ACA; odds ratio (OR) = 0.4, P < 0.001) and more frequently anti-topoisomerase-I autoantibodies (ATA) positive (OR = 1.2, P = 0.068), while BP were less likely to be ACA and ATA positive than were WP [OR(ACA) = 0.3, P < 0.001; OR(ATA) = 0.5, P = 0.020]. AP had less often (OR = 0.7, P = 0.06) and BP more often (OR = 2.7, P < 0.001) diffuse skin involvement than had WP.AP and BP were more likely to have pulmonary hypertension [OR(AP) = 2.6, P < 0.001; OR(BP) = 2.7, P = 0.03 vs WP] and a reduced forced vital capacity [OR(AP) = 2.5, P < 0.001; OR(BP) = 2.4, P < 0.004] than were WP. AP more often had an impaired diffusing capacity of the lung than had BP and WP [OR(AP vs BP) = 1.9, P = 0.038; OR(AP vs WP) = 2.4, P < 0.001]. After RP onset, AP and BP had a higher hazard to die than had WP [hazard ratio (HR) (AP) = 1.6, P = 0.011; HR(BP) = 2.1, P < 0.001].Conclusion. Compared with WP, and mostly independent of geographical location, AP have a faster and earlier disease onset with high prevalences of ATA, pulmonary hypertension and forced vital capacity impairment and higher mortality. BP had the fastest disease onset, a high prevalence of diffuse skin involvement and nominally the highest mortality

Development of a Low-Cost Electronic Wheelchair with Obstacle Avoidance Feature

A low-cost electronic wheelchair was designed and developed which can perform the similar functions and features as a commercially available wheelchair. It also provides obstacle avoidance capability as added value. The electronic wheelchair was  realized by modification of a lightweight manual wheelchair. It uses two electric motors each of 320 W 24 V DC, 5-24 VDC 6 A H-bride drivers, and a 12 V 17 Ah rechargeable lead acid battery. It equipped with switches, joystick, infrared sensors and ultrasonic sensors. A GizduinoAtMega 328 microcontroller is used to read and interpret commands. User’s acceptance evaluation results shows that the developed low-cost wheelchair is able to receive and interpret commands provided by the joystick, detect if a person  is seated on it, navigate to avoid obstacles as well as to detect edge and stairs. Technical evaluation result shows that on a flat surface it could move at the speed of around 39.9 m/minute without load and 32 m/minute with 80 kg load. At 10 degrees inclined surface, the maximum weight limit is 30 kg with the speed of 12 m/minute. At 20 degrees inclined surface, the maximum weight limit is 10 kg with the speed of 3 m/minute. Regarding cost, it is just a fraction of a cost compared to the commercially available model. Therefore, the developed wheelchair offers an option for potential users who cannot afford to buy the commercially available one

Médico - Paciente 4 - ME06 201702

Médico Paciente 4 es un curso de especialidad de la Escuela de Medicina, de carácter teórico-práctico dirigido a los estudiantes del 5° nivel, que contribuye a desarrollar la Competencia General de comunicación oral, Nivel 2 y la Competencia Específica de profesionalismo, Nivel 1. El objetivo de la línea de cursos Médico - Paciente es formar al estudiante en el conocimiento y práctica de la atención Primaria en Salud, que actúe como agente de cambio en los diversos campos de acción del profesional médico y con los valores de equidad, solidaridad y el derecho al más alto nivel de salud posible. En este curso el estudiante se involucra con los aspectos de promoción y prevención de las principales enfermedades crónicas e infecciosas y continúa su formación en habilidades clínicas en el componente preventivo promocional

Médico - Paciente 4-ME06-201702

Médico Paciente 4 es un curso de especialidad de la Escuela de Medicina de carácter teórico-práctico dirigido a los estudiantes del 5° nivel que contribuye a desarrollar la Competencia General de comunicación oral Nivel 2 y la Competencia Específica de profesionalismo Nivel 1. El objetivo de la línea de cursos Médico - Paciente es formar al estudiante en el conocimiento y práctica de la atención Primaria en Salud que actúe como agente de cambio en los diversos campos de acción del profesional médico y con los valores de equidad solidaridad y el derecho al más alto nivel de salud posible. En este curso el estudiante se involucra con los aspectos de promoción y prevención de las principales enfermedades crónicas e infecciosas y continúa su formación en habilidades clínicas en el componente preventivo promocional