Metrofission project: An overview of the ENEA contribution

Abstract The paper describes the progress made by ENEA-INMRI in the research carried out within the framework of the Joint Research Project (JRP) ENG08 Metrofission of the European Metrology Research Programme (EMRP). This JRP aims to solve important problems related to the development of the Generation IV (GenIV) nuclear power plants in Europe as required by new demands of energy supplies that must be secure, sustainable, of high quality and also able to reduce the green house gas emissions. In the Metrofission project the ENEA-INMRI is directly involved in three Working Packages (WPs): the WP6, that aims to develop a portable Triple-to-Double-Coincidence-Ratio (TDCR) system for measuring in-situ of pure beta radionuclides; the WP7, devoted to the development of modern acquisition techniques based on Digital Coincidence Counting (DCC) with high sampling speed for radionuclide standardization; the WP8, leaded by ENEA-INMRI, which takes into account the impact of the project toward the end-users and the nuclear industry. The new prototype of the ENEA-INMRI portable TDCR counter will be presented. The preliminary results obtained in the activity measurements of 14C and 63Ni standard sources carried out by the new counter equipped with the new front-end electronics based on the CAEN Digitizer DT5720 will be discussed

Lessons Learned on the Tensile and Bond Behavior of Fabric Reinforced Cementitious Matrix (FRCM) Composites

Fabric Reinforced Cementitious Matrix (FRCM) composites represent an effective, compatible and cost-efficient solution for strengthening and retrofitting existing structures. A strong research effort was done to investigate the tensile and bond properties of these materials, as well as the overall behaviour of strengthened members. A Round Robin Test was organized by Rilem TC 250-CSM on 28 FRCM composites comprising basalt, carbon, glass, PBO, aramid and steel textiles, embedded in either cement, lime or geopolymer mortars, to collect an experimental dataset and define test protocols. This paper collects the outcomes of this study to highlight fundamental properties of FRCM and to investigate the variability of test results. Grid spacing, equivalent thickness of the textiles and mechanical properties of FRCM composites, such as stiffness, tensile and bond strength, are provided. Based on the comparison of experimental outcomes, the scatter of the mechanical properties is estimated, as a consequence of the quasi-brittle behaviour of the inorganic matrix and its sensitivity to manufacturing, curing and handling processes. Eventually, the influence of testing implementation, such as gripping method and measuring techniques, are outlined

Mammographic breast density in infertile and parous women

BACKGROUND: Mammographic breast density is a useful marker for breast cancer risk, as breast density is considered one of the strongest breast cancer risk factors. The study objective was to evaluate and compare mammographic breast density in infertile and parous women, as infertility may be associated with high breast density and cancer occurrence. METHODS: This study evaluated mammographic breast density using two different systems, BIRADS and Boyd. A selected patient population of 151 women with primary infertility (case group) was compared to 154 parous women who had at least one previous pregnancy (control group). Both groups were premenopausal women aged ≥ 35. RESULTS: Evaluation of mammographic features showed that 66.9% of case group patients and 53.9% of control group patients were classified BIRADS-3/BIRADS-4; p < 0.05. Adjusted Odds ratio for the case group in the categories BIRADS-3/BIRADS-4 was 1.78 (95% CI: 1.10-2.89). Using the Boyd classification system, 53.6% of case group patients and 31.8% of control group patients were classified E/F; p < 0.05. Adjusted Odds ratio for case group patients in Boyd categories E/F was 2.05 (95 % CI: 1.07-3.93). CONCLUSIONS: Both systems yielded a higher percentage of increased breast density in the case group. Boyd and BIRADS classification systems indicate to what extend breast cancer lesions may be missed on mammography due to masking by dense tissue. Therefore, patients with a high BIRADS or Boyd score should undergo further investigation

The use of hysteroscopic metroplasty with diode laser to increase endometrial volume in women with septate uterus: preliminary results

Background: Septate uterus is a common Mullerian ducts anomaly. The aim of our pilot study was the evaluation of diode laser hysteroscopic metroplasty efficacy to increase endometrial volume in women with septate uterus. Results: We prospectively enrolled 10 consecutive patients with septate uterus undergoing office hysteroscopic metroplasty with diode laser between February and November 2019. Endometrial volume was evaluated before and 3 months after surgery using 3D transvaginal ultrasound. The surgical procedure was uncomplicated in all patients, the endometrial volume increased at 3 months follow-up (the median increase was 1.9 cm3 (range 1.7– 2.1), and there was a complete removal of septum with no intrauterine synechiae at follow-up hysteroscopy. Conclusions: Office hysteroscopic metroplasty with diode laser is a safe procedure and has preliminary showed to increase endometrial volume. The increase in endometrial volume by 3D-TV US could be used as a prognostic factor for the reproductive outcomes

Shake table testing of a low-impact technology for the seismic protection of stone masonry

This paper presents a novel low-impact technique for the seismic protection of fair-face masonry walls. The proposed strengthening solution involves the use of carbon-fibre reinforced polymer (CFRP) connectors installed from the outside by perforating the stone elements, combined with grout injections. The connectors cover ¾ of the wall thickness, so as to leave the inner surface undisturbed. Once the work is completed, they are also substantially invisible. Shake table tests were carried out under natural accelerograms on two full-scale irregular multi-leaf stone masonry wall specimens. In order to replicate materials and construction technique of the Apennine historical buildings, the prototypes were made from stones recovered from the debris of a settlement in the municipality of Accumoli (RI, Italy), and the mortar was designed to reproduce lime-poor mortars surveyed in the field. The experimental setup was designed to induce out-of-plane vertical bending under base seismic motion, while allowing the vertical displacement of the wall top. One specimen was tested “as-built” and the other one was tested strengthened, to investigate the gain in seismic performance, the limitation of progressive damage accumulation and the effects on dynamic properties

The effect of metal cations on the aqueous behavior of dopamine. Thermodynamic investigation of the binary and ternary interactions with cd2+, cu2+ and uo22+ in nacl at different ionic strengths and temperatures

The interactions of dopamine [2-(3,4-Dihydroxyphenyl)ethylamine, (Dop−)] with cadmium(II), copper(II) and uranyl(VI) were studied in NaCl(aq) at different ionic strengths (0 ≤ I/mol dm−3 ≤ 1.0) and temperatures (288.15 ≤ T/K ≤ 318.15). From the elaboration of the experimental data, it was found that the speciation models are featured by species of different stoichiometry and stability. In particular for cadmium, the formation of only MLH, ML and ML2 (M = Cd2+; L = dopamine) species was obtained. For uranyl(VI) (UO22+), the speciation scheme is influenced by the use of UO2(acetate)2 salt as a chemical; in this case, the formation of ML2, MLOH and the ternary MLAc (Ac = acetate) species in a wide pH range was observed. The most complex speciation model was obtained for the interaction of Cu2+ with dopamine; in this case we observed the formation of the following species: ML2, M2L, M2L2, M2L2(OH)2, M2LOH and ML2OH. These speciation models were determined at each ionic strength and temperature investigated. As a further contribution to this kind of investigation, the ternary interactions of dopamine with UO22+/Cd2+ and UO22+/Cu2+ were investigated at I = 0.15 mol dm−3 and T = 298.15K. These systems have different speciation models, with the MM’L and M2M’L2OH [M = UO22+; M’ = Cd2+ or Cu2+, L = dopamine] common species; the species of the mixed Cd2+ containing system have a higher stability with respect the Cu2+ containing one. The dependence on the ionic strength of complex formation constants was modelled by using both an extended Debye–Hückel equation that included the Van’t Hoff term for the calculation of the formation enthalpy change values and the Specific Ion Interaction Theory (SIT). The results highlighted that, in general, the entropy is the driving force of the process. The quantification of the effective sequestering ability of dopamine towards the studied cations was evaluated by using a Boltzmann-type equation and the calculation of pL0.5 parameter. The sequestering ability was quantified at different ionic strengths, temperatures and pHs, and this resulted, in general, that the pL0.5 trend was always: UO22+ &gt; Cu2+ &gt; Cd2+

Effect of Tomato Peel Extract Grown under Drought Stress Condition in a Sarcopenia Model

Tomatoes and their derivates represent an important source of natural biologically active components. The present study aims to investigate the protective effect of tomato peel extracts, grown in normal (RED-Ctr) or in drought stress (RED-Ds) conditions, on an experimental model of sarcopenia. The phenolic profile and total polyphenols content (TPC) of RED-Ctr and RED-Ds were determined by Ultra High-Performance Liquid Chromatography (UHPLC) analyses coupled to electrospray ionization high-resolution mass spectrometry (ESI-HR-MS). Human skeletal muscle myoblasts (HSMM) were differentiated in myotubes, and sarcopenia was induced by dexametha- sone (DEXA) treatment. Differentiation and sarcopenia were evaluated by both real-time PCR and immunofluorescent techniques. Data show that myosin heavy chain 2 (MYH2), troponin T (TNNT1), and miogenin (MYOG) were expressed in differentiated myotubes. 5 μg Gallic Acid Equivalent (GAE/mL) of TPC from RED-Ds extract significantly reduced muscle atrophy induced by DEXA. Moreover, Forkhead BoxO1 (FOXO1) expression, involved in cell atrophy, was significantly decreased by RED-Ds extract. The protective effect of tomato peel extracts depended on their qualitative polyphenolic composition, resulting effectively in the in vitro model of sarcopenia

Interpreting doubly special relativity as a modified theory of measurement

In this article we develop a physical interpretation for the deformed (doubly) special relativity theories (DSRs), based on a modification of the theory of measurement in special relativity. We suggest that it is useful to regard the DSRs as reflecting the manner in which quantum gravity effects induce Planck-suppressed distortions in the measurement of the "true" energy and momentum. This interpretation provides a framework for the DSRs that is manifestly consistent, non-trivial, and in principle falsifiable. However, it does so at the cost of demoting such theories from the level of "fundamental" physics to the level of phenomenological models -- models that should in principle be derivable from whatever theory of quantum gravity one ultimately chooses to adopt.Comment: 18 pages, plain LaTeX2