181 research outputs found
The B --> pi form factor from light-cone sum rules in soft-collinear effective theory
Recently, we have derived light-cone sum rules for exclusive B-meson decays
into light energetic hadrons from correlation functions within soft-collinear
effective theory. In these sum rules the short-distance scale refers to
``hard-collinear'' interactions with virtualities of order \Lambda_{QCD} m_b.
Hard scales (related to virtualities of order m_b^2) are integrated out and
enter via external coefficient functions in the sum rule. Soft dynamics is
encoded in light-cone distribution amplitudes for the B-meson, which describe
both the factorizable and non-factorizable contributions to exclusive B-meson
decay amplitudes. Factorization of the correlation function has been verified
to one-loop accuracy. Thus, a systematic separation of hard, hard-collinear,
and soft dynamics in the heavy-quark limit is possible.Comment: 5 pages, one figur
On the contribution of the electromagnetic dipole operator to the decay amplitude
We construct a factorization theorem that allows to systematically include
QCD corrections to the contribution of the electromagnetic dipole operator in
the effective weak Hamiltonian to the decay
amplitude. We first rederive the known result for the leading-order QED box
diagram, which features a double-logarithmic enhancement associated to the
different rapidities of the light quark in the meson and the
energetic muons in the final state. We provide a detailed analysis of the
cancellation of the related endpoint divergences appearing in individual
momentum regions, and show how the rapidity logarithms can be isolated by
suitable subtractions applied to the corresponding bare factorization theorem.
This allows us to include in a straightforward manner the QCD corrections
arising from the renormalization-group running of the hard matching coefficient
of the electromagnetic dipole operator in soft-collinear effective theory, the
hard-collinear scattering kernel, and the -meson distribution amplitude.
Focusing on the contribution from the double endpoint logarithms, we derive a
compact formula that resums the leading-logarithmic QCD corrections.Comment: 33 pages, 3 figure
SCET sum rules for B->P and B->V transition form factors
We investigate sum rules for heavy-to-light transition form factors at large
recoil derived from correlation functions with interpolating currents for light
pseudoscalar or vector fields in soft-collinear effective theory (SCET). We
consider both, factorizable and non-factorizable contributions at leading power
in the Lambda/m_b expansion and to first order in the strong coupling constant
alpha_s, neglecting contributions from 3-particle distribution amplitudes in
the B-meson. We pay particular attention to various sources of parametric and
systematic uncertainties. We also discuss certain form factor ratios where part
of the hadronic uncertainties related to the B-meson distribution amplitude and
to logarithmically enhanced alpha_s corrections cancel.Comment: 27 pages, 19 figures, minor corrections, matches journal versio
Quantification of exhaled propofol is not feasible during single-lung ventilation using double-lumen tubes : A multicenter prospective observational trial
Background: Volatile propofol can be measured in exhaled air and correlates to
plasma concentrations with a time delay. However, the effect of single-lung ventilation on exhaled propofol is unclear. Therefore, our goal was to evaluate exhaled propofol concentrations during single-lung compared to double-lung ventilation using
double-lumen tubes.
Methods: In a first step, we quantified adhesion of volatile propofol to the inner surface of double-lumen tubes during double- and single-lumen ventilation in vitro. In a
second step, we enrolled 30 patients scheduled for lung surgery in two study centers.
Anesthesia was provided with propofol and remifentanil. We utilized left-sided
double-lumen tubes to separately ventilate each lung. Exhaled propofol concentrations were measured at 1-min intervals and plasma for propofol analyses was sampled every 20 min. To eliminate the influence of dosing on volatile propofol
concentration, exhalation rate was normalized to plasma concentration.
Results: In-vitro ventilation of double-lumen tubes resulted in increasing propofol
concentrations at the distal end of the tube over time. In vitro clamping the bronchial
lumen led to an even more pronounced increase (Î AUC +62%) in propofol gas concentration over time. Normalized propofol exhalation during lung surgery was 31%
higher during single-lung compared to double-lung ventilation.
Conclusion: During single-lung ventilation, propofol concentration in exhaled air, in
contrast to our expectations, increased by approximately one third. However, this
observation might not be affected by change in perfusion-ventilation during singlelung ventilation but rather arises from reduced propofol absorption on the inner
surface area of the double-lumen tube. Thus, it is only possible to utilize exhaled
propofol concentration to a limited extent during single-lung ventilation.
Registration of Clinical Trial: DRKS-ID DRKS00014788 (www.drks.de)
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