1,107 research outputs found
Parenting gifted and talented children: What are the key child behaviour and parenting issues?
Objective: The literature on gifted and talented children is limited. Little is known about the types and nature of difficulties experienced by gifted and talented children, and even less known about parenting issues related to parenting a gifted and talented child. The aim of the present study was to describe children's behavioural and emotional adjustment, and the factors that contribute to children's difficulties, as well as to examine the styles of discipline used by parents of gifted and talented children and their level of confidence in managing specific parenting tasks
Quantitative trait loci conferring grain mineral nutrient concentrations in durum wheat 3 wild emmer wheat RIL population
Mineral nutrient malnutrition, and particularly
deficiency in zinc and iron, afflicts over 3 billion people
worldwide. Wild emmer wheat, Triticum turgidum ssp.
dicoccoides, genepool harbors a rich allelic repertoire for
mineral nutrients in the grain. The genetic and physiological
basis of grain protein, micronutrients (zinc, iron,
copper and manganese) and macronutrients (calcium,
magnesium, potassium, phosphorus and sulfur) concentration
was studied in tetraploid wheat population of 152
recombinant inbred lines (RILs), derived from a cross
between durum wheat (cv. Langdon) and wild emmer
(accession G18-16). Wide genetic variation was found
among the RILs for all grain minerals, with considerable
transgressive effect. A total of 82 QTLs were mapped for
10 minerals with LOD score range of 3.2â16.7. Most QTLs
were in favor of the wild allele (50 QTLs). Fourteen pairs
of QTLs for the same trait were mapped to seemingly
homoeologous positions, reflecting synteny between the A
and B genomes. Significant positive correlation was found
between grain protein concentration (GPC), Zn, Fe and Cu,
which was supported by significant overlap between the
respective QTLs, suggesting common physiological and/or
genetic factors controlling the concentrations of these
mineral nutrients. Few genomic regions (chromosomes 2A,
5A, 6B and 7A) were found to harbor clusters of QTLs for
GPC and other nutrients. These identified QTLs may
facilitate the use of wild alleles for improving grain
nutritional quality of elite wheat cultivars, especially in
terms of protein, Zn and Fe
Collective emotions online and their influence on community life
E-communities, social groups interacting online, have recently become an
object of interdisciplinary research. As with face-to-face meetings, Internet
exchanges may not only include factual information but also emotional
information - how participants feel about the subject discussed or other group
members. Emotions are known to be important in affecting interaction partners
in offline communication in many ways. Could emotions in Internet exchanges
affect others and systematically influence quantitative and qualitative aspects
of the trajectory of e-communities? The development of automatic sentiment
analysis has made large scale emotion detection and analysis possible using
text messages collected from the web. It is not clear if emotions in
e-communities primarily derive from individual group members' personalities or
if they result from intra-group interactions, and whether they influence group
activities. We show the collective character of affective phenomena on a large
scale as observed in 4 million posts downloaded from Blogs, Digg and BBC
forums. To test whether the emotions of a community member may influence the
emotions of others, posts were grouped into clusters of messages with similar
emotional valences. The frequency of long clusters was much higher than it
would be if emotions occurred at random. Distributions for cluster lengths can
be explained by preferential processes because conditional probabilities for
consecutive messages grow as a power law with cluster length. For BBC forum
threads, average discussion lengths were higher for larger values of absolute
average emotional valence in the first ten comments and the average amount of
emotion in messages fell during discussions. Our results prove that collective
emotional states can be created and modulated via Internet communication and
that emotional expressiveness is the fuel that sustains some e-communities.Comment: 23 pages including Supporting Information, accepted to PLoS ON
Falling behind: life expectancy in US counties from 2000 to 2007 in an international context
<p>Abstract</p> <p>Background</p> <p>The United States health care debate has focused on the nation's uniquely high rates of lack of insurance and poor health outcomes relative to other high-income countries. Large disparities in health outcomes are well-documented in the US, but the most recent assessment of county disparities in mortality is from 1999. It is critical to tracking progress of health reform legislation to have an up-to-date assessment of disparities in life expectancy across counties. US disparities can be seen more clearly in the context of how progress in each county compares to international trends.</p> <p>Methods</p> <p>We use newly released mortality data by age, sex, and county for the US from 2000 to 2007 to compute life tables separately for each sex, for all races combined, for whites, and for blacks. We propose, validate, and apply novel methods to estimate recent life tables for small areas to generate up-to-date estimates. Life expectancy rates and changes in life expectancy for counties are compared to the life expectancies across nations in 2000 and 2007. We calculate the number of calendar years behind each county is in 2000 and 2007 compared to an international life expectancy time series.</p> <p>Results</p> <p>Across US counties, life expectancy in 2007 ranged from 65.9 to 81.1 years for men and 73.5 to 86.0 years for women. When compared against a time series of life expectancy in the 10 nations with the lowest mortality, US counties range from being 15 calendar years ahead to over 50 calendar years behind for men and 16 calendar years ahead to over 50 calendar years behind for women. County life expectancy for black men ranges from 59.4 to 77.2 years, with counties ranging from seven to over 50 calendar years behind the international frontier; for black women, the range is 69.6 to 82.6 years, with counties ranging from eight to over 50 calendar years behind. Between 2000 and 2007, 80% (men) and 91% (women) of American counties fell in standing against this international life expectancy standard.</p> <p>Conclusions</p> <p>The US has extremely large geographic and racial disparities, with some communities having life expectancies already well behind those of the best-performing nations. At the same time, relative performance for most communities continues to drop. Efforts to address these issues will need to tackle the leading preventable causes of death.</p
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Improved Constraints on Sterile Neutrino Mixing from Disappearance Searches in the MINOS, MINOS+, Daya Bay, and Bugey-3 Experiments.
Searches for electron antineutrino, muon neutrino, and muon antineutrino disappearance driven by sterile neutrino mixing have been carried out by the Daya Bay and MINOS+ collaborations. This Letter presents the combined results of these searches, along with exclusion results from the Bugey-3 reactor experiment, framed in a minimally extended four-neutrino scenario. Significantly improved constraints on the θ_{Îźe} mixing angle are derived that constitute the most constraining limits to date over five orders of magnitude in the mass-squared splitting Îm_{41}^{2}, excluding the 90% C.L. sterile-neutrino parameter space allowed by the LSND and MiniBooNE observations at 90% CL_{s} for Îm_{41}^{2}<13ââeV^{2}. Furthermore, the LSND and MiniBooNE 99% C.L. allowed regions are excluded at 99% CL_{s} for Îm_{41}^{2}<1.6âeV^{2}
WNT signalling in prostate cancer
Genome sequencing and gene expression analyses of prostate tumours have highlighted the potential importance of genetic and epigenetic changes observed in WNT signalling pathway components in prostate tumours-particularly in the development of castration-resistant prostate cancer. WNT signalling is also important in the prostate tumour microenvironment, in which WNT proteins secreted by the tumour stroma promote resistance to therapy, and in prostate cancer stem or progenitor cells, in which WNT-β-catenin signals promote self-renewal or expansion. Preclinical studies have demonstrated the potential of inhibitors that target WNT receptor complexes at the cell membrane or that block the interaction of β-catenin with lymphoid enhancer-binding factor 1 and the androgen receptor, in preventing prostate cancer progression. Some WNT signalling inhibitors are in phase I trials, but they have yet to be tested in patients with prostate cancer
New results of 116Cd double beta decay study with 116CdWO4 scintillators
A new phase of 116Cd double beta decay experiment is in progress in the
Solotvina Underground Laboratory. Four enriched 116CdWO4 scintillators with
total mass 339 g are used in a set up, whose active shield is made of 15
natural CdWO4 crystals (20.6 kg). The background rate in the energy interval
2.5-3.2 MeV is 0.03 counts/y*kg*keV. The half-life for 2-neutrino 2-beta decay
of 116Cd is measured as T{1/2}(2-neutrino) =
[2.6+-0.1(stat)-0.4+0.7}(syst)]*10**19 y. The T{1/2} limits for neutrinoless
2-beta decay of 116Cd are set as T{1/2} >= 0.7(2.5)*10**23 y at 90%(68%) C.L.
for transition to ground state of 116Sn, while for decays to the first 2+ and
second 0+ excited levels of 116Sn as T{1/2}>=1.3(4.8)*10**22 y and
>=0.7(2.4)*10**22 y with 90%(68%) C.L., respectively. For 0-neutrino 2-beta
decay with emission of one or two Majorons, the limits are T{1/2}(0-neutrino
M1) >=3.7(5.8)*10**21 y and T{1/2}(0-neutrino M2)>=5.9(9.4)*10**20 y at
90%(68%) C.L. Restrictions on the value of the neutrino mass, right-handed
admixtures in the weak interaction, and the neutrino-Majoron coupling constant
are derived as: m(neutrino)<=2.6(1.4) eV, eta <=3.9*10**-8, lambda
<=3.4*10**-6, and g{M}<= 12(9.5)*10**-5 at 90%(68%) C.L., respectively.Comment: 28 pages, 9 figures (LaTeX). Phys. Rev. C (in press
"I really should've gone to the doctor": older adults and family caregivers describe their experiences with community-acquired pneumonia
BACKGROUND: Responding to acute illness symptoms can often be challenging for older adults. The primary objective of this study was to describe how community-dwelling older adults and their family members responded to symptoms of community-acquired pneumonia (CAP). METHODS: A qualitative study that used face-to-face semi-structured interviews to collect data from a purposeful sample of seniors aged 60+ and their family members living in a mid-sized Canadian city. Data analysis began with descriptive and interpretive coding, then advanced as the research team repeatedly compared emerging thematic categories to the raw data. Searches for disconfirming evidence and member checking through focus groups provided additional data and helped ensure rigour. RESULTS: Community-acquired pneumonia symptoms varied greatly among older adults, making decisions to seek care difficult for them and their family members. Both groups took varying amounts of time as they attempted to sort out what was wrong and then determine how best to respond. Even after they concluded something was wrong, older adults with confirmed pneumonia continued to wait for days, to over a week, before seeking medical care. Participants provided diverse reasons for this delay, including fear, social obligations (work, family, leisure), and accessibility barriers (time, place, systemic). Several older adults and family members regretted their delays in seeking help. CONCLUSION: Treatment-seeking delay is a variable, multi-phased decision-making process that incorporates symptom assessment plus psychosocial and situational factors. Public health and health care professionals need to educate older adults about the potential causes and consequences of unnecessary waits. Such efforts may reduce the severity of community-acquired pneumonia upon presentation at clinics and hospitals, and that, in turn, could potentially improve health outcomes
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