Therapeutic effects of combined meloxicam and glucosamine sulfate treatment on patients with osteoarthritis, and its effect on serum CTX-Ⅰ, CTX-Ⅱ, COMP and MMP-3

Purpose: To study the therapeutic influence of meloxicam-glucosamine sulfate combination in patients with osteoarthritis and their effect on serum CTX-I, CTX-II, COMP and MMP-3. Methods: A total of 88 patients with osteoarthritis were assigned to control (n = 44) and treatment groups (n = 44), using the random number table method. Control group was given 7.5 mg of meloxicam, while treatment group received 0.5 g of glucosamine sulfate capsule in addition to meloxicam. Both groups were treated continuously for 8 weeks. Serum levels of C-terminal telopeptide of type I collagen (CTX-I), C-terminal telopeptide of type II collagen (CTX-II), cartilage oligomeric matrix protein (COMP) and matrix metalloproteinase-3 (MMP-3) were compared for the two groups after treatment. Results: Lysholm score significantly increased in the two groups after treatment. Serum CTX-I, CTX-II, COMP and MMP-3 in the two groups were significantly lower than before treatment, but the reductions were more pronounced in the treatment group (p < 0.05). During treatment, mild vomiting and pruritus of the skin appeared in both groups, but these were relieved after symptomatic treatment without any serious adverse reactions. Conclusion: Treatment with a combination of meloxicam and glucosamine sulfate produces significant beneficial effects in patients with osteoarthritis by reduction of clinical symptoms, pain relief and reduction of serum CTX-I, CTX-II, MMP-3 and COMP

Enhanced superconductivity in TiO epitaxial thin films

Titanium oxides have many fascinating optical and electrical properties, such as the superconductivity at 2 K in cubic titanium monoxide (TiO) polycrystalline bulk. However, the lack of TiO single crystals or epitaxial films has prevented systematic investigations on its superconductivity. Here, we report the basic superconductivity characterizations of cubic TiO films epitaxially grown on (0001)-oriented α-Al2O3 substrates. The magnetic and electronic transport measurements confirmed that TiO is a type-II superconductor and the recorded high Tc is about 7.4 K. The lower critical field (Hc1) at 1.9 K, the extrapolated upper critical field Hc2(0), and coherence length are about 18 Oe, 13.7 T, and 4.9 nm, respectively. With increasing pressure, the value of Tc shifts to lower temperature while the normal state resistivity increases. Our results on the superconducting TiO films confirm the strategy to achieve higher Tc in the epitaxial films, which may be helpful for finding more superconducting materials in various related systems

Local fusion networks with chained residual pooling for video action recognition

Action recognition is an important yet challenging problem. We here present a novel method, multistage local fusion networks with residual connections, to boost the performance of video action recognition. In realistic videos, an action instance may have a long time span and some frames may suffer from deteriorated object appearance due to motion blur or video defocus. Our method enhances the per-frame representation by capturing information from neighboring frames. We propose a local fusion block which considers neighboring frames to capture appearance and local motion information for generating per-frame representation. Our local fusion is performed in a multistage manner allowing feature fusion from varying neighborhood sizes in the temporal dimension. We employ residual connections in the fusion blocks to enable effective gradient propagation through the whole network allowing effective end-to-end training. We achieve competitive results on two challenging and public available datasets, namely HMDB51 and UCF101, which shows the effectiveness of the proposed method.Accepted versio

Enhanced superconductivity in TiO epitaxial thin films

Titanium oxides have many fascinating optical and electrical properties, such as the superconductivity at 2 K in cubic titanium monoxide (TiO) polycrystalline bulk. However, the lack of TiO single crystals or epitaxial films has prevented systematic investigations on its superconductivity. Here, we report the basic superconductivity characterizations of cubic TiO films epitaxially grown on (0001)-oriented α-Al2O3 substrates. The magnetic and electronic transport measurements confirmed that TiO is a type-II superconductor and the recorded high Tc is about 7.4 K. The lower critical field (Hc1) at 1.9 K, the extrapolated upper critical field Hc2(0), and coherence length are about 18 Oe, 13.7 T, and 4.9 nm, respectively. With increasing pressure, the value of Tc shifts to lower temperature while the normal state resistivity increases. Our results on the superconducting TiO films confirm the strategy to achieve higher Tc in the epitaxial films, which may be helpful for finding more superconducting materials in various related systems

LRPL-VIO: A Lightweight and Robust Visual–Inertial Odometry with Point and Line Features

Visual-inertial odometry (VIO) algorithms, fusing various features such as points and lines, are able to improve their performance in challenging scenes while the running time severely increases. In this paper, we propose a novel lightweight point–line visual–inertial odometry algorithm to solve this problem, called LRPL-VIO. Firstly, a fast line matching method is proposed based on the assumption that the photometric values of endpoints and midpoints are invariant between consecutive frames, which greatly reduces the time consumption of the front end. Then, an efficient filter-based state estimation framework is designed to finish information fusion (point, line, and inertial). Fresh measurements of line features with good tracking quality are selected for state estimation using a unique feature selection scheme, which improves the efficiency of the proposed algorithm. Finally, validation experiments are conducted on public datasets and in real-world tests to evaluate the performance of LRPL-VIO and the results show that we outperform other state-of-the-art algorithms especially in terms of speed and robustness

In situ coagulation-electrochemical oxidation of leachate concentrate: A key role of cathodes

To efficiently remove organic and inorganic pollutants from leachate concentrate, an in situ coagulation-electrochemical oxidation (CO-EO) system was proposed using Ti/Ti4O7 anode and Al cathode, coupling the “super-Faradaic” dissolution of Al. The system was evaluated in terms of the removal efficiencies of organics, nutrients, and metals, and the underlying cathodic mechanisms were investigated compared with the Ti/RuO2–IrO2 and graphite cathode systems. After a 3-h treatment, the Al-cathode system removed 89.0% of COD and 36.3% of total nitrogen (TN). The TN removal was primarily ascribed to the oxidation of both ammonia and organic-N to N2. In comparison, the Al-cathode system achieved 3–10-fold total phosphorus (TP) (62.6%) and metal removals (>80%) than Ti/RuO2–IrO2 and graphite systems. The increased removals of TP and metals were ascribed to the in situ coagulation of Al(OH)3, hydroxide precipitation, and electrodeposition. With the reduced scaling on the Al cathode surface, the formation of Al3+ and electrified Al(OH)3 lessened the requirement for cathode cleaning and increased the bulk conductivity, resulting in increased instantaneous current production (38.9%) and operating cost efficiencies (48.3 kWh kgCOD−1). The present study indicated that the in situ CO-EO process could be potentially used for treating persistent wastewater containing high levels of organic and inorganic ions

A Fluorescent Sensor-Assisted Paper-Based Competitive Lateral Flow Immunoassay for the Rapid and Sensitive Detection of Ampicillin in Hospital Wastewater

In this study, a convenient assay method has been developed based on labeled functional nucleic acids (H-DNA) and a competitive fluorescent lateral flow immunoassay (CF-LFI) for ampicillin (AMP) detection. Herein, we designed the tunable AMP probes for AMP detection based on the AMP aptamer, and the secondary DNA fragment. The probes can generate tunable signals on the test line (T line) and control line (C line) according to the concentration of AMP. The accuracy of detection was improved by optimizing the tunable AMP probes. Under the optimal conditions, the linear concentration of AMP detection is ranged from 10 to 200 ng/L with a limit of quantitation (LOQ) value of 2.71 ng/L, and the recovery is higher than 80.5 %. Moreover, the developed method shows the potential application for AMP detection in the hospital wastewater

Exact Analytical Magnetic Field Analysis, Optimization Design and Realization of an Eccentric Magnetic Harmonic Gear

The eccentric magnetic harmonic gear (EMHG) has a high efficiency and high gear ratio capability for large torque transmission. The air gap magnetic field can be calculated using an exact analytical model. The analytical approach is based on the theoretically accurate hyperbolic cotangent transformation method. The relative permeance function, which is derived from the impact of rotor eccentricity, can be used to find the eccentric air gap magnetic field solution. The proposed analytical approach is employed as the basis for a genetic algorithm that is used to develop and optimize the EMHG. The analytical results are in good agreement with the finite element method results, which verifies the correctness and validity of the proposed analytical model. The experimental measurements on the dual-stage EMHG confirm the validity of the analytical prediction