5 research outputs found

    Transforming the ESL Experience: Assessing First-Year International Students in the Instruction Classroom

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    In 2015-16, the Undergraduate Library evaluated the impact of library instruction on English as a Second Language student learning. Findings included the need for multi-format instructional support in the flipped library instruction environment and a stronger emphasis on source evaluation. This project is part of the program “Assessment in Action: Academic Libraries and Student Success” which is undertaken by the Association of College and Research Libraries (ACRL) in partnership with the Association for Institutional Research and the Association of Public and Land-grant Universities. The program, a cornerstone of ACRL's Value of Academic Libraries initiative, is made possible by the Institute of Museum and Library Services.Ope

    Autoantibodies to muscarinic acetylcholine receptors found in patients with primary biliary cirrhosis

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    <p>Abstract</p> <p>Background</p> <p>Autoantibodies to the human muscarinic acetylcholine receptor of the M3 type (hmAchR M3) have been suggested to play an etiopathogenic role in Sjögren's syndrome. Primary biliary cirrhosis (PBC) often is associated with this syndrome. Therefore, we studied the co-presence of hmAchR M3 autoantibodies in patients with PBC.</p> <p>Methods</p> <p>Frequency of hmAchR M3 autoantibodies was assessed by Western blotting analysis as well as by an ELISA using a 25-mer peptide of the 2<sup>nd </sup>extracellular loop of hmAchR M3. Co-localization of hmAchR M3/PBC-specific autoantibodies was studied by confocal laser scanning microscopy. Finally, sera from patients with PBC as well as from healthy controls were tested.</p> <p>Results</p> <p>Western blotting analysis as well as results from ELISA testing revealed a significantly enhanced IgG reactivity in PBC patients in contrast to healthy controls. Co-localization of autoantibodies with the hmAchR M3 receptor-specific autoantibodies was observed in 10 out of 12 PBC-patients but none of the 5 healthy controls. Antibodies of the IgM type were not found to be affected.</p> <p>Conclusions</p> <p>For the first time, our data demonstrate the presence of autoantibodies to the hmAchR M3 in PBC patients. These findings might contribute to the understanding of the pathogenesis of this disease. Further studies have to focus on the functionality of hmAchR M3 autoantibodies in PBC patients.</p

    Autocomplete as Research Tool: A Study on Providing Search Suggestions

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    As the library website and on its online searching tools become the primary “branch” many users visit for their research, methods for providing automated, context-sensitive research assistance need to be developed to guide unmediated searching towards the most relevant results.&nbsp; This study examines one such method, the use of autocompletion in search interfaces, by conducting usability tests on its use in typical academic research scenarios.&nbsp; The study reports notable findings on user preference for autocomplete features, and suggests best practices for their implementation
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