ASSESSING THE EFFECTIVNESS OF GOVERNMENT PROGRAMS

The article presents the results of the analysis of the approved by law methodology for assessing the effectiveness of the implementation of state programs of the Russian Federation. The paper ascertains that the methodology has a number of shortcomings in terms of calculating individual indicators, does not take into account the industry specifics of measures. In order to eliminate the shortcomings of the current methodological base, the authors proposed an adjusted methodology for assessing efficiency, which involves the use of mathematical modeling methods, qualitative assessment criteria, modified coefficients. At the same time, the weighting coefficients of the main criteria of the method were revised – the study proposes to use the method of Saati hierarchies. The developed proposals are aimed at improving the accuracy and reliability of the results of assessing the effectiveness of government programs

ОСОБЛИВОСТІ МОТИВАЦІЇ ДО НАВЧАННЯ У ЮНАКІВ З ПОРУШЕННЯМ СЛУХУ

Проаналізовано теоретичний матеріал за даною проблемою. Проведено емпіричне дослідження, в результаті якого були виявлені особливості мотивації до навчання у юнаків з порушенням слуху

Asymmetric Electrostatic Dodecapole: Compact Bandpass Filter with Low Aberrations for Momentum Microscopy

Imaging energy filters in photoelectron microscopes and momentum microscopes employ spherical fields with deflection angles of 90{\deg}, 180{\deg} and even 2 x 180{\deg}. These instruments are optimized for high energy resolution, yet they come along with image aberrations when they are operated in high transmission mode with medium energy resolution. Here we present a new approach for bandpass-filtered imaging in real or reciprocal space, using an asymmetric electrostatic dodecapole. This multipole enables energy-dispersive beam deflection and correction of image aberrations up to the 3rd order. Owing to a deflection angle of only 4{\deg}, the total beam displacement in the filter is just ~10 mm. Hence, the entire instrument is compact and just requires a straight vacuum tube. The multipole is framed by transfer lenses in the entrance and exit branch. Two sets of 16 entrance and exit apertures with different sizes on piezomotor-driven holders allow selecting the desired resolution. The combination of apertures and dodecapole acts as a bandpass pre-selector in a high-energy time-of-flight momentum microscope at the hard X-ray beamline P22 at PETRA-III (DESY, Hamburg). At pass energies between 400 and 600 eV it transmits electrons with kinetic energies in the range of 20-40 eV and thus effectively eliminates unwanted intensity from higher-energy electrons in the ToF analyzer. At low pass energies, the instrument allows energy-filtered imaging without subsequent ToF analysis. In a laboratory experiment the 4{\deg} prototype reached < 500 meV resolution, which is sufficient for fast survey studies in the X-ray range.Comment: 16 pages, 6 figures, 26 reference

NEW TENDENCIES IN DIAGNOSTICS AND TREATMENT OF DISEASES OF THE CERVIX (LITERATURE REVIEW)

In the problem of resolving the pathology of the cervix in recent years, a lot of information about etiology, causes of origin, diagnosis and treatment has been accumulated. The article summarizes the new possibilities of diagnosis and treatment of the pathology of the cervix, which contributes to a significant improvement in the resolution of the problem of the pathology of the cervix. There are 4 main groups of etiologic factors that lead to morphofunctional changes in the cervical epithelium. In the course of a violation of the transformation of the epithelialization of the cylindrical epithelium, the violation of local and humoral immunity is important. The definition of apoptosis index is a new modern method for predicting the development of precancerous and cervical cancer. Routine but informative methods for diagnosing cervical pathologies such as cytological and colposcopic, in recent years, have been replenished with an important immunohistochemical diagnostic method for detecting p161NK4a cellular protein, as well as by fluorescence spectrometry. The presented complex of diagnostic researches allows us to choose the method of adequate treatment of pathological processes taking into account the age of the patient, the nature and degree of severity of epithelial changes, the type of cervical and vaginal flora, as well as the hormonal status of the patient and concomitant pathology

Valence-transition-induced changes of the electronic structure in EuPd2_2Si2_2

We present results of hard X-ray angle-resolved photoemission spectroscopy and photoemission diffraction measurements performed on high-quality single crystals of the valence transition compound EuPd$_2$Si$_2$ for temperatures 25~K $\leq$ T $\leq$ 300~K. At low temperatures we observe a Eu $4f$ valence $v=2.5$, % occupation number $n=6.5$, which decreases to $v=2.1$ for temperatures above the valence transition around $T_V \approx 160$~K. The experimental valence numbers resulting from an evaluation of the Eu(III)/Eu(II) $3d$ core levels, are used for calculating band structures using density functional theory. The valence transition significantly changes the band structure as determined by angle-resolved photoemission spectroscopy. In particular, the Eu $5d$ valence bands are shifted to lower binding energies with increasing Eu $4f$ occupancy. To a lesser extent, bands derived from the Si $3p$ and Pd $4d$ orbitals are also affected. This observation suggests a partial charge transfer between Eu and Pd/Si sites. Comparison with {\it ab-initio} theory shows a good agreement with experiment, in particular concerning the unequal band shift with increasing Eu $4f$ occupancy

Evaluation of methods of modeling and formation of experimental allergic encephalomyelitis

Experimental autoimmune (allergic) encephalomyelitis (EAE) induced by intradermal injection of homogenate of the brain, spinal cord and peripheral nerve with Freund’s stimulator, refers to a true autoimmune disease of the nervous syste

Observation of time-reversal symmetry breaking in the band structure of altermagnetic RuO2_2

Altermagnets are an emerging third elementary class of magnets. Unlike ferromagnets, their distinct crystal symmetries inhibit magnetization while, unlike antiferromagnets, they promote strong spin polarization in the band structure. The corresponding unconventional mechanism of timereversal symmetry breaking without magnetization in the electronic spectra has been regarded as a primary signature of altermagnetism, but has not been experimentally visualized to date. We directly observe strong time-reversal symmetry breaking in the band structure of altermagnetic RuO$_2$ by detecting magnetic circular dichroism in angle-resolved photoemission spectra. Our experimental results, supported by ab initio calculations, establish the microscopic electronic-structure basis for a family of novel phenomena and functionalities in fields ranging from topological matter to spintronics, that are based on the unconventional time-reversal symmetry breaking in altermagnets

Лучевая и эндоскопическая семиотика рака легкого

We examined 82 lung cancer patients admitted to the S.P.Botkin hospital for pneumonia. As a result of complex examination including radiological methods, bronchoscopy and biopsy central lung cancer was diagnosed in 68 patients, bronchioloalveolar carcinomas were revealed in 8 ones, and peripheral carcinomas with the lung tissue destruction were found in 6 patients. Principal radiological signs of the central lung carcinoma were a tumour in the lung root and ventilation disorders of a lung part. Main endoscopic features of the central lung carcinoma were tumour impression, invasion, or peribronchial growth. Bronchioloalveolar carcinomas were characterized radiologically with infiltrates and endoscopically with great volume of liquid foamy secretion. The radiological features of peripheral carcinomas with the lung tissue destruction were nodular outline of a tumour, sometimes with spiculations, and irregular inner interface.Были обследованы 82 больных раком легкого (РЛ), поступивших в больницу им. С.П.Боткина с диагнозом пневмония. После проведения комплексного обследования, включающего в себя методы лучевой диагностики и бронхоскопию с биопсией, центральный РЛ диагностирован у 68 больных, бронхиоло-альвеолярный рак — у 8, распадающийся периферический РЛ — у 6 пациентов. Основными рентгенологическими признаками центрального РЛ являлось наличие опухоли в корне легкого и нарушение вентиляции участка легкого. Основным эндоскопическим признаком центрального РЛ была экзофитная, эндофитная или перибронхально растущая опухоль. Бронхиоло-альвеолярный рак рентгенологически характеризовался инфильтратами, а во время бронхоскопии определялось очень большое количество жидкого пенистого секрета. Отличительными особенностями рентгенологической картины распадающегося периферического РЛ были бугристость наружных контуров образования, местами лучистого характера, и неровность внутреннего контура полости