313 research outputs found
The Effect of the Third Dimension on Rough Surfaces Formed by Sedimenting Particles in Quasi-Two-Dimensions
The roughness exponent of surfaces obtained by dispersing silica spheres into
a quasi-two-dimensional cell is examined. The cell consists of two glass plates
separated by a gap, which is comparable in size to the diameter of the beads.
Previous work has shown that the quasi-one-dimensional surfaces formed have two
distinct roughness exponents in two well-defined length scales, which have a
crossover length about 1cm. We have studied the effect of changing the gap
between the plates to a limit of about twice the diameter of the beads.Comment: 4 pages, 4 figures, submitted to IJMP
Drift without flux: Brownian walker with a space dependent diffusion coefficient
Space dependent diffusion of micrometer sized particles has been directly
observed using digital video microscopy. The particles were trapped between two
nearly parallel walls making their confinement position dependent.
Consequently, not only did we measure a diffusion coefficient which depended on
the particles' position, but also report and explain a new effect: a drift of
the particles' individual positions in the direction of the diffusion
coefficient gradient, in the absence of any external force or concentration
gradient.Comment: 4 pages, 4 ps figures, include
Influence of flow confinement on the drag force on a static cylinder
The influence of confinement on the drag force on a static cylinder in a
viscous flow inside a rectangular slit of aperture has been investigated
from experimental measurements and numerical simulations. At low enough
Reynolds numbers, varies linearly with the mean velocity and the viscosity,
allowing for the precise determination of drag coefficients and
corresponding respectively to a mean flow parallel and
perpendicular to the cylinder length . In the parallel configuration, the
variation of with the normalized diameter of the
cylinder is close to that for a 2D flow invariant in the direction of the
cylinder axis and does not diverge when . The variation of
with the distance from the midplane of the model reflects the
parabolic Poiseuille profile between the plates for while it
remains almost constant for . In the perpendicular configuration,
the value of is close to that corresponding to a 2D system
only if and/or if the clearance between the ends of the cylinder
and the side walls is very small: in that latter case,
diverges as due to the blockage of the flow. In other cases, the
side flow between the ends of the cylinder and the side walls plays an
important part to reduce : a full 3D description of the flow is
needed to account for these effects
Resonant energy transfer in electron-driven proton pumps
We examine proton and electron transport in living cell membranes and show that the Coulomb interaction leads to a resonant energy transfer, from the electrons to protons during their simultaneous tunnelings, which allows the proton pump to work. The proton pump efficiency is controlled by the electron voltage build-up, external temperature, and the molecular electrostatics driving the electron and proton energies to their resonant conditions. We also show that physiological (e.g., human body) temperatures are optimal for the operation of this proton pump. (© 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/57928/1/398_ftp.pd
Diffusion in pores and its dependence on boundary conditions
We study the influence of the boundary conditions at the solid liquid
interface on diffusion in a confined fluid. Using an hydrodynamic approach, we
compute numerical estimates for the diffusion of a particle confined between
two planes. Partial slip is shown to significantly influence the diffusion
coefficient near a wall. Analytical expressions are derived in the low and high
confinement limits, and are in good agreement with numerical results. These
calculations indicate that diffusion of tagged particles could be used as a
sensitive probe of the solid-liquid boundary conditions.Comment: soumis \`a J.Phys. Cond. Matt. special issue on "Diffusion in
Liquids, Polymers, Biophysics and Chemical Dynamics
Many-particle hydrodynamic interactions in parallel-wall geometry: Cartesian-representation method
This paper describes the results of our theoretical and numerical studies of
hydrodynamic interactions in a suspension of spherical particles confined
between two parallel planar walls, under creeping-flow conditions. We propose a
novel algorithm for accurate evaluation of the many-particle friction matrix in
this system--no such algorithm has been available so far.
Our approach involves expanding the fluid velocity field into spherical and
Cartesian fundamental sets of Stokes flows. The interaction of the fluid with
the particles is described using the spherical basis fields; the flow scattered
with the walls is expressed in terms of the Cartesian fundamental solutions. At
the core of our method are transformation relations between the spherical and
Cartesian basis sets. These transformations allow us to describe the flow field
in a system that involves both the walls and particles.
We used our accurate numerical results to test the single-wall superposition
approximation for the hydrodynamic friction matrix. The approximation yields
fair results for quantities dominated by single particle contributions, but it
fails to describe collective phenomena, such as a large transverse resistance
coefficient for linear arrays of spheres
Association of Coronary Microvascular Dysfunction With Heart Failure Hospitalizations and Mortality in Heart Failure With Preserved Ejection Fraction:A Follow-up in the PROMIS-HFpEF Study
Background: Coronary microvascular dysfunction (CMD) is common in heart failure with preserved ejection fraction (HFpEF). We assessed the association of CMD with hospitalization and mortality in HFpEF. Methods and Results: We assessed the 1-year outcomes in patients from the PROMIS-HFpEF study, a prospective observational study of patients with chronic stable HFpEF undergoing coronary flow reserve measurements. Outcomes were (1) time to cardiovascular (CV) death/first HF hospitalization, (2) CV death/recurrent HF hospitalizations, (3) all-cause death/first HF hospitalization, and (4) first and (5) recurrent all-cause hospitalizations. CMD was defined as coronary flow reserve of Conclusions: In this exploratory assessment of the prognostic role of CMD in HFpEF, CMD was independently associated with primarily CVand HF-specific events. The high prevalence of CMD and its CV and HF specific prognostic role suggest CMD may be a potential treatment target in HFpEF
Optical trap stiffness in the presence and absence of spherical aberrations
Optical traps are commonly constructed with high-numerical-aperture objectives. Oil-immersion objectives suffer from spherical aberrations when used for imaging in aqueous solutions. The effect of spherical aberrations on trapping strength has been modeled by approximation, and only a few experimental results are available in the case of micrometer-sized particles. We present an experimental study of the dependence of lateral and axial optical-trap stiffness on focusing depth for polystyrene and silica beads of 2 μm diameter by using oil- and water-immersion objectives. We demonstrate a strong depth dependence of trap stiffness with the oil-immersion objective, whereas no depth dependence was observed with the water-immersion objective. © 2006 Optical Society of America
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