4 research outputs found

    Notes

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    Notes by Richard A. Molique, F. Louis Fautsch, John A. Berry, Joseph A. McCabe, Stephen P. Banas, Robert Devine, John J. Locher, and J. S. Montedonico

    Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.

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    Due to their similarities in anatomy, physiology, and pharmacology to humans, mice are a valuable model system to study the generation and mechanisms modulating conventional outflow resistance and thus intraocular pressure. In addition, mouse models are critical for understanding the complex nature of conventional outflow homeostasis and dysfunction that results in ocular hypertension. In this review, we describe a set of minimum acceptable standards for developing, characterizing, and utilizing mouse models of open-angle ocular hypertension. We expect that this set of standard practices will increase scientific rigor when using mouse models and will better enable researchers to replicate and build upon previous findings

    Notes

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    Notes by Richard A. Molique, F. Louis Fautsch, John A. Berry, Joseph A. McCabe, Stephen P. Banas, Robert Devine, John J. Locher, and J. S. Montedonico

    Notes

    No full text
    Notes by Richard A. Molique, F. Louis Fautsch, John A. Berry, Joseph A. McCabe, Stephen P. Banas, Robert Devine, John J. Locher, and J. S. Montedonico
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