22 research outputs found
Isolated tumour microparticles induce endothelial microparticle release in vitro
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 26/11/2019
- Field of study
© 2019 Wolters Kluwer Health, Inc. All rights reserved. Cancer induces a hypercoagulable state, resulting in an increased risk of venous thromboembolism. One of the mechanisms driving this is tissue factor (TF) production by the tumour, released in small lipid bound microparticles. We have previously demonstrated that tumour cell line media-induced procoagulant changes in HUVEC. The aim of this study was to investigate the effect of tumour microparticles and recombinant human TF (rhTF) on the endothelium. Procoagulant microparticles from the PANC-1 cell line were harvested by ultrafiltration. HUVEC were then incubated with these procoagulant microparticles or rhTF. Flow cytometry was used to investigate the effect of endothelial cell surface protein expression and microparticle release. Microparticles but not soluble TF was responsible for the procoagulant activity of cell-free tumour media. We also demonstrated an increase in endothelial microparticle release with exposure to tumour microparticles, with a positive linear relationship observed (R2 = 0.6630 P †0.0001). rhTF did not induce any of the changes observed with microparticles. Here we demonstrate that procoagulant activity of tumour cell line media is dependent on microparticles, and that exposure of endothelial cells to these microparticles results in an increase in microparticle release from HUVEC. This suggests a mechanism of transfer of procoagulant potential from the cancer to the remote endothelium
A Far-Ultraviolet Survey of 47 Tucanae.II The Long-Period Cataclysmic Variable AKO 9
- Author
- Publication venue
- 'University of Chicago Press'
- Publication date
- 05/09/2003
- Field of study
We present time-resolved, far-ultraviolet (FUV) spectroscopy and photometry
of the 1.1 day eclipsing binary system AKO 9 in the globular cluster 47
Tucanae. The FUV spectrum of AKO 9 is blue and exhibits prominent C IV and He
II emission lines. The spectrum broadly resembles that of long-period,
cataclysmic variables in the galactic field.
Combining our time-resolved FUV data with archival optical photometry of 47
Tuc, we refine the orbital period of AKO 9 and define an accurate ephemeris for
the system. We also place constraints on several other system parameters, using
a variety of observational constraints. We find that all of the empirical
evidence is consistent with AKO 9 being a long-period dwarf nova in which mass
transfer is driven by the nuclear expansion of a sub-giant donor star. We
therefore conclude that AKO 9 is the first spectroscopically confirmed
cataclysmic variable in 47 Tuc.
We also briefly consider AKO 9's likely formation and ultimate evolution.
Regarding the former, we find that the system was almost certainly formed
dynamically, either via tidal capture or in a 3-body encounter. Regarding the
latter, we show that AKO 9 will probably end its CV phase by becoming a
detached, double WD system or by exploding in a Type Ia supernova.Comment: 40 pages, 11 figures, to appear in the Dec 20 issue of ApJ; minor
changes to match final published versio
SS Ari: a shallow-contact close binary system
- Author
- A. Claret
- A.F. Lanza
- C. Hoffmeister
- C.-H. Kim
- C.-H. Kim
- C.A. Tout
- D. Kopal
- D.H. Bradstreet
- D.R. Faulkner
- E.H. Kramer
- F. Agerer
- G. Russo
- H. Huth
- I.B. Biro
- J. Hubscher
- J. Hubscher
- J. Hubscher
- J. Hubscher
- J. Kaluzny
- J. Zhang
- J.-J. He
- J.H. Applegate
- L. Liu
- L. Liu
- L.-J. Li
- L.B. Lucy
- O. Demircan
- O.K. Odynskaya
- P.G. Niarchos
- P.P. Rainger
- Q. Liu
- R.E. Wilson
- R.E. Wilson
- R.E. Wilson
- R.G. Samec
- S.-B. Qian
- S.-B. Qian
- S.-B. Qian
- S.-B. Qian
- S.-B. Qian
- S.-B. Qian
- S.-B. Qian
- S.-B. Qian
- S.-B. Qian
- S.C. Barden
- S.M. Rucinski
- T. Borkovits
- T. Krajci
- T. Pribulla
- V. Keskin
- W. Braune
- W. Braune
- W. Braune
- W. Braune
- W. Braune
- W. Lu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 10/03/2011
- Field of study
Two CCD epochs of light minimum and a complete R light curve of SS Ari are
presented. The light curve obtained in 2007 was analyzed with the 2003 version
of the W-D code. It is shown that SS Ari is a shallow contact binary system
with a mass ratio q=3.25 and a degree of contact factor f=9.4(\pm0.8%). A
period investigation based on all available data shows that there may exist two
distinct solutions about the assumed third body. One, assuming eccentric orbit
of the third body and constant orbital period of the eclipsing pair results in
a massive third body with M3â=1.73Mââ and P_3=87.0yr.Onthecontrary,assumingcontinuousperiodchangesoftheeclipsingpairtheorbitalperiodoftertiaryis37.75yranditsmassisabout0.278M_{\odot}$. Both of the cases
suggest the presence of an unseen third component in the system.Comment: 28 pages, 9 figures and 5 table
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard VĂ©ronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis VĂ©ronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
- Berks Michael
- Bethel Graeme
- Beugelsdijk Tony J.
- Bhakta Rita
- Bhuchar Venita
- Bi Shihua
- Bian Xuemeng
- Bieri Tamberlyn
- Bimage Kesha E.
- Bird Christine
- Birditt Brian
- Birney Ewan
- Birney Ewan
- Birren Bruce
- Bissell Helen
- Biswalo Kaneza
- Bituin Aleksandr
- Black Stacey
- Blackburne-Maze Suzanne
- Blair Jessica Anne
- Blakey Sarah
- Blanks Tia
- Blasiar Darin
- Blazej Robert
- Blitshsteyn Berta
- Blomstrom David B.
- Bloom Scott
- Bloom Toby
- Blumer Heather
- Blye Jason
- Blyth Peter R.
- Blöcker Helmut
- Boatright Elizabeth
- Boehm John
- Boen Juanan
- Boguslavskiy Leonid
- Bolton Christel
- Bolund Lars
- Bondoc Marnel
- Bonfield James
- Bonnett Ralph
- Bonnin David
- Border Richard
- Borowsky Mark
- Borzym Katja
- Boukhgalter Boris
- Bowen Eric
- Bradley Amanda
- Bradshaw-Cordum Holly
- Brady Nicola
- Brandriff Brigitte F.
- Brannon Wade
- Branscomb Elbert
- Bray Jason
- Bray-Allen Sarah
- Brettin Thomas
- Bridgeman Anne
- Bridgers Michael
- Brimhall Angela K.
- Brokstein Peter
- Brook Jonathan
- Brooking Shane
- Brottier Philippe
- Brown Andrew
- Brown Clive
- Brown Jacqui
- Brown Margaret
- Brown Mary
- Brown Mary J.
- Brown Michael
- Brown Nancy C.
- Bruce David D.
- Bruce Robert
- Bruno William J.
- Bruskiewich Richard
- Bryant Jackie
- Bryant Jennifer E.
- Bryant Nathaniel P.
- BrĂŒls Thomas
- Buatsi Delali
- Buck David
- Buckingham Judith M.
- Buckle Veronica
- Buczek Donald
- Budd Claire
- Buhay Christian J.
- Bulbul Kerem
- Buller Sarah
- Bunker Nathan
- Burberry Jill
- Burch Paula Ellen
- Burford Deborah
- Burgess Joanne
- Burgin Matt
- Burkett Carrie E.
- Burkhart-Schultz Karolyn
- Burrell Kevin L.
- Burrill Wayne
- Burrows Christine
- Burton Christine
- Burton John
- Butcher Phil
- Butler Adam
- Butler Jon
- Butler Paul
- Caenepeel Sean
- Cahill Patrick
- Cai Tianjing
- Cai Zhen
- Cairns Murray
- Calderon Eliana
- Callen David F.
- Camarata Jody
- Camire David
- Camm Nick
- Campbell Christopher
- Campbell Connie S.
- Campbell Evelyn W.
- Campbell Mary I.
- Campbell Mary L.
- Campo Kevin
- Canning Bruno
- Cao Ting
- Cao Yuzhu
- Caoile Chenier
- Cardenas Faviola
- Cardenas Lolo
- Cardenas Veronica
- Carder Carol
- Carder Paul
- Carpenter Kelly
- Carrano Anthony V.
- Carriere Jason
- Carter Jason
- Carter Kelvin
- Carter Nigel
- Caruso Lauren
- Casias Kristal
- Cattolico Laurence
- Cavanna Tamara
- Cavazos Iracema
- Cavazos Sandra R.
- Ceasar Heather
- Cedroni Maria
- Cepeda Mario
- Chacko Joseph
- Chain Patrick
- Chalk Shani
- Challacombe Jean F.
- Chan Ka
- Chan Sheryl N.
- Chan Yee Man
- Chang Jean L.
- Chapman Jarrod
- Chapman Joanna
- Chapple Jeffrey
- Charles Rachel
- Chasteen Leslie A.
- Chavarria Simeon
- Chazaro Bruno
- Chen Baoxian
- Chen Bin
- Chen Chira
- Chen Chong
- Chen Chong
- Chen Chun-Nan
- Chen Cong
- Chen Ellson
- Chen Hsiu-Chuan
- Chen Jianlong
- Chen Jie
- Chen Jin
- Chen Junbao
- Chen Lihong
- Chen Lixia
- Chen Ray
- Chen Shu
- Chen Tong
- Chen Xiaoyun
- Chen Xinyi
- Chen Yanjiong
- Chen Yiyu
- Chen Zhu
- Chen Zhu
- Chen Zhu
- Cheng Jan-Fang
- Cheng Zhihua
- Chertkov Olga
- Cheshatsang Yama
- Chi Cheng
- Chi Han C.
- Chillingworth Neil
- Chin Sylvia
- Chinn Corey
- Chinwalla Asif
- Chissoe Stephanie
- Chiu Sally
- Chothia Tom
- Christensen Mari
- Christopoulos Constantine
- Chu Joseph
- Chui Connie
- Chung A
- Cinkowsky Michael J.
- Citroen Mieke
- Clack Rob
- Clamp Michele
- Clark Anthea
- Clark Graham
- Clark Kevin
- Clark Lynn
- Clark Lynn M.
- Clark Richard
- Clark Sarah
- Clark Sue
- Clarke Adrian
- Clarke Betty
- Clarke Eddie
- Clarke Kay
- Clarke Laura
- Clawson Hiram
- Clee Chris
- Clegg Shelia
- Clerc Blankenburg Kerstin Petra
- Cleveland David
- Clifford Karen
- Clifton Sandra W.
- Coates Julia
- Cobley Victoria
- Cockrell Raynard
- Coffey Alison
- Cofield Jackie
- Coggill Penelope
- Cohn Judith D.
- Colayco Rick
- Cole Lotte
- Collier Rachael
- Collings Simon
- Collins Francis S.
- Collins John
- Collins Philip
- Collymore Al
- Colman Louise
- Combs Jessie
- Comstock Robin
- Cong Bin
- Conner Richard
- Connolly Anthony
- Connolly Karen
- Conquer Jennie
- Conrad Ansgar
- Conroy Donald
- Considine Tony
- Constance Doug
- Cook April
- Cook Leanna
- Cooke Patrick
- Cooper Jonathan
- Cooper Rachel
- Cooper Robert
- Copeland Alex
- Coppola Maria
- Copsey Teresa
- Corby Nicole
- Cordes Matt
- Cordray Rebecca
- Cornell Christine
- Cornell Earl
- Cornell Linda
- Cornell Ruth
- Corum Ben
- Cottage Amanda
- Cotton Sara
- Coulson Alan
- Couronne Olivier
- Courtney Laura P.
- Coville Gez
- Cox Anthony
- Cox Caroline D.
- Cox Tony
- Coxhill Robert
- Coyle Marcus D.
- Craig Matthew
- Crane Tom
- Crawford Amanda L.
- Crawley Matt
- Cree Andrew
- Crespeau Hervé
- Crew Victor
- Critchlow Terrance
- Critz Paul
- Cruaud Corinne
- Cuff James
- Cui Hongjuan
- Cui Jinhui
- Cui Peng
- Cui Peng
- Culley Karl
- Cummings Auli
- Cummings Kirsti
- Cummings Paul
- Cummings Stephanie
- Cuomo Christina A.
- Curran Adam
- Curwen Valery
- Cutts Jeffrey
- Czubayko Martin
- D\u27Souza Lisa Marie
- Da Silva Corinne
- Dai Li
- Dalin Eillen
- Dang Michelle
- Danganan Linda
- Daniels Rachael
- Dathorne Stephanie R.
- Daum Christopher
- David Robert
- Davidson Lucy
- Davidson Stuart
- Davies Jonathon
- Davies Joy
- Davies Nicholas
- Davies Robert
- Davila Mary Louise
- Davis Candi Mon\u27et
- Davis Cheryl
- Davis Clay
- Davis Jayne
- Davis John
- Davis Matthew
- Davy-Carroll Latarsha
- Dawoe Tenzin
- Dawson Elisabeth
- De Anda Claudia
- De Latorre Andrea
- Deadman Rebecca
- Dean Peter
- Dear Simon
- Dearden Frances
- DeArellano Kurt
- Deaven Larry I.
- Deaven Larry L.
- Deere Kerry
- DeGray Stewart
- Degusta David
- Deguzman Maria
- Dehal Paramvir
- Delgado Marcos
- Delgado Oliver
- Delhaunty Kimberley
- Deloukas Panos
- Deng Yajun
- Dennis Janet
- Denson Shawn
- Denys Mirian
- Deramo Christine
- Desai Anu
- Detter John C.
- Devlin Laurie
- Dewar Ken
- Dhami Pawandeep
- Dhongsar Chemey
- Dias Jennifer
- Dias Victoria
- Dibartolo Genevieve
- Dibling Catherine
- Dickson Mark
- Diekhans Mark
- Dietz-Band Jeanne
- Digennaro Richard
- Dilts Karen
- Dimitrijevic-Bussod Mira
- Ding Hao
- Ding Keyue
- Ding Li
- Ding Yan
- Dinh Huyen H.
- Dixon Kami
- Do Long
- Dobbs Ruth
- Dobson Richard
- Dockree Catherine
- Doddington Daniel
- Dodsworth Steven
- Doggett Norman
- Doggett Norman A.
- Dong Hui
- Dong Kimberly
- Dong Wei
- Dong Wei
- Dong Xiaojia
- Donlin Jeremy E.
- Dooley Kathy
- Dooling David
- Dorje Passang
- Dorjee Kunsang
- Dorris Lester
- Dorsett Victor
- Doucette-Stamm Lynn
- Douthwaite Karen J.
- Down Thomas
- Draper Heather
- Du Feiyu
- Du Hui
- Du Yutao
- Duarte Suzanne
- Dubchak Inna
- Duffy Noah
- Dugan-Rocha Shannon
- Dunham Andrew
- Dunham Ian
- Dunn Adam M.
- Dunn Anne
- Dunn Matthew
- Dunwell Erin
- Dupes Alan
- Durbin Kenneth J.
- Durbin Richard
- Durham Jillian
- Dutta Ireena
- Dwyer Ruth
- Dyer Lauren
- Dziuda Darius
- Earnhardt Christopher D.
- Earthrowl Mark
- Eastham Emma
- Eastham Timothy
- Eaves Kristy A.
- Eckenberg Ralph
- Edgar Darren
- Edionwe Susan Omwanghe Osayanro
- Edwards Carol
- Edwards Jennifer
- Edwards Karen
- Egan Amy
- Eichler Evan
- Eichler Evan
- Ejima Fumio
- Elkin Chris
- Ellington Andrew
- Elliot David
- Elliot Glendoria
- Elliot Jeffrey
- Ellwood Matthew
- Emberson Becky
- Emelianenko Natalia
- Emery-Cohen Alexandra J.
- Endrizzi Matthew
- Engh Ger van den
- Engle David
- Erickson Jeffery
- Erler Anne Marie
- Errington Helen
- Escobar Julio
- Escotto Michael
- Eugene Craig S.
- Evans Gareth
- Evans John
- Evans Katie
- Evans Richard
- Eveleth Gerald
- Eyras Eduardo
- Fan Hongyuan
- Fan Keke
- Fang Jianqiu
- Farina Abderrahim
- Faro Susan
- Faulkner Louisa
- Fawcett Joseph J.
- Fechtel Kim
- Fellingham Charlotte
- Felming Claire
- Felsenfeld Adam
- Feltwell Theresa
- Feng Guodong
- Feng Haiyan
- Feng Jie
- Feng Xiaoli
- Fennell Stephen
- Ferguson Alicia
- Fernandez Sonia
- Fernandez-Suarez Xose
- Fernando Pushpa Ranjani
- Ferriera Pat
- Fertitta Anne
- Fey Jim
- Fidel Patrick
- Fields Elizabeth
- Fink Marie
- Finley Maria C.
- Finn Robert
- Fischer Heather
- Fischer Laurice
- Fisher Shelia
- Fitch Pat
- Fitzgerald Mike
- Flack Tina
- Flagg Nicole
- Flanagan J.
- Fleming Kerry
- Flint Jonathan
- Flint Mark
- Flowers Dave
- Floyd Yvonne
- Foley Karen
- Folta Peg
- Fong Jonathan
- Fonknechten NĂșrua
- Footman Simon
- Forbes Lisa D.
- Ford Amanda F.
- Foster Myre J.
- Fotopulos Dea
- Fourcade Matthew
- Fowler John
- Fox Jessica
- Frame Deborah
- Francis Matthew
- Francis Stephen
- Frankel Ken
- Frankish Adam
- Frankland John
- Fraser Audrey
- Fraser David
- Frazier Marvin
- French Lisa
- Fricker David
- Fridlyand Jane
- Fronick Catrina
- Frost Carole
- Frost Daniel
- Frost Jackie
- Frost Lorna
- Fu Gang
- Fu Gang
- Fu Gang
- Fu Qiushi
- Fujioka Michiru
- Fujiyama Asao
- Fukawa Rintaro
- Fuller Liam
- Fuller Sharin
- Fullerton Kathryn
- Fulton Lucinda A.
- Fulton Robert S.
- Furey Terrence S.
- Furuhashi Mie
- Förste Silke
- Gabisi Abdul M.
- Gage Diane
- Gaige Tony
- Galgoczy Petra
- Gallegos Celsa
- Galvez Michael
- Gammon Stuart
- Gao Anwu
- Gao Jimei
- Gao Quan
- Gao Yang
- Gao Yimei
- Garcia Carmen
- Garcia Emilio
- Garcia Marvin
- Garcia Ricardo M, III
- Garcia-Martinez Antonio
- Gardner Alison
- Gardner Alison
- Garduno Consuelo
- Gardyna Steph
- Garner Patrick
- Garner Toni T.
- Garnes Jeffrey A.
- Garnett Jane
- Garza Melissa
- Gatewood Joseph M.
- Gatland Leigh
- Gatland Lindsay
- Gattung Stacie
- Gay Laura
- Gearin Gary
- Gebreyesus Binyam
- Gelein Cynthia
- Gelpke Maartin
- Gench Stephanie L.
- Geng Jianing
- Georgescu Anca
- Geotina Amy
- Ghori Jilur
- Ghose Sayantan
- Gibbs Ben
- Gibbs Richard A.
- Gibson Diane
- Gibson Elizabeth
- Gifford Mary
- Gil Isaias
- Gilbert James
- Gilby Lisa
- Gill Rachel
- Gillet Will
- Gillson Christopher
- Gilna Paul
- Gimmel Verena
- Gingrich Jeff
- Giovanelli Kira
- Glavina Tijana
- Glithero Rebecca
- Glöckner Gernot
- Gnerre Sante
- Gnirke Andreas
- Gold Darren
- Golinveaux Kristen
- Gomez Maria
- Gong Guanghui
- Gong Jinying
- Gonzales Eidelyn
- Gonzalez Guillermo B.
- Gooderham April
- Goodstadt Leo
- Goodstein David
- Goodwin Lynne A.
- Gordon Catherine
- Gordon Laurie A.
- Gordon Seth
- Gorton Matthew
- Gorvad Ann
- Gould Christine
- Goyea Ernest
- Goyette Audra
- Grady Deborah I.
- Grady Michelle L.
- Grafham Darren
- Graham Joe
- Grandbois Edward
- Grant Jennifer
- Grant Michael
- Grant Susan
- Graves Tina A.
- Gray Bruce
- Gray Emma
- Gray Lain
- Green Lisa
- Greenhalgh James
- Greenhill Joe
- Gregg Philippa
- Gregory Simon
- Grewal Nennu
- Gribble Susan
- Griffith Jeffrey K.
- Griffiths Coline
- Griffiths Ed
- Griffiths Mark
- Griffiths-Jones Sam
- Grigoriev Igor
- Grimwood Jane
- Grocock Russell
- Groza Matthew
- Gu Jingli
- Gu Jun
- Gu Jun
- Gu Wenyi
- Gu Wenyi
- Gu Xiaochang
- Guan Qiaoning
- Guarin Hannibal
- Guel Metzalli
- Guerra William
- Guevara Whitney V.
- Gui Qi
- Gunaratne Preethi
- Gunning Kate
- Guo Daorong
- Guo Jane
- Guo Lili
- Gustafson Erik
- Guthrie Ian
- Guyer Mark
- Gwilliam Rhian
- Gyaltsen Kunsang
- Gyapay GĂĄbor
- Görlich Yvonne
- Ha Chi
- Hafez Nabil
- Haglund Krista
- Hagopian Daniel
- Hagos Birhane
- Haim Allen
- Hajek Patrick
- Hall Brett Lynn
- Hall Brittany
- Hall Jennifer
- Hall Rebekah
- Hall-Tamly Gretta
- Halls Karen
- Hallsworth-Pepin Kym
- Hamada Junko
- Hamilton Cerissa
- Hamilton Keelan A.
- Hamilton Matt
- Hamlett John
- Hamlett John
- Hammon Nancy
- Hammond Martin
- Hammond Sha
- Hammond Sian
- Hamza Khalid
- Han Guiqing
- Han Shunsheng
- Han Xurong
- Hanak Vincent A.
- Hancock Julie
- Harbes Brandy A.
- Harding Adam
- Harkins C. Richard
- Harley Joanne
- Harper David
- Harper Georgina
- Harper Patrik
- Harradence Grant
- Harris Anthony
- Harrison Charlene-Lou
- Harrison Elliot
- Harrison Ruth
- Hart Elizabeth
- Hasegawa Tomoko
- Hashimoto Etsuko
- Hashimoto Wakako
- Hassan Daniel
- Hatcher Beath
- Hattori Masahira
- Haugen Eric
- Haussler David
- Havlak Paul
- Hawes Alicia C.
- Hawkins Ebere Sylvia Onyirioha
- Hawkins Natalie
- Hawkins Trevor
- Hawley Kellie
- Haydu Lauren
- Hayes Kerry
- He Fengying
- He Jiaying
- He Lin
- Heaford Andrew
- Heath Paul
- Heathcott Rosemary
- Heilig Roland
- Heiner Cheryl
- Heinze Ivonne
- Heitmann Katja
- Helfenbein Keven
- Heller Andrew
- Hellsten Uffe
- Hembry Cathy
- Henderson Carl
- Henderson Nicholas
- Henderson Nina
- Hendrix David
- Hennig Steffen
- Henning Karla
- Hepa Victor
- Herd Tim
- Herman Charles
- Hernandez Judith
- Hernandez Omar
- Herseim Allyson
- Hewitt Stephen
- Heyen Joshua
- Higgs Douglas
- Hildebrand Carl E.
- Hillier LaDeana
- Hillyard Guy
- Hines Sandra
- Hinkins Russell
- Hinrichs Angela S.
- Hitchens Matthew Edward
- Ho Issac
- Ho Sara-Jane
- Hodgson Anne V.
- Hodgson David
- Hoffman Susan M.G.
- Hoffs Michael
- Hogues Marilyn E.
- Holden Jane
- Holdgate Janet
- Hollaway Mara
- Hollins Barbara
- Holloway Ele
- Holmes Andrea
- Holmes Ian
- Holmes Sarah
- Holroyd Simon
- Holtz Ann
- Holtzer Caleb
- Homsi Deana K.
- Homsi Farah J.
- Honan Tracy
- Hood Leroy
- Hooper Alison
- Hopewell Lucy
- Hopkins Ben
- Horne Jennifer
- Hornett Gary
- Hornischer Klaus
- Hornsby Amber
- Hornsby Geoff
- Hornsby Tony
- Horsley Sharon
- Horton Roger
- Hosage-Norman Catherine
- Hosoda Kei
- Hosono Katsuhiro
- Hosseini Roya
- Hou Shunfang
- Hou Xiaodi
- Houde Nathan
- Howard Philip
- Howard Stephanie R.
- Howden Philip
- Howe Kevin
- Howell Gareth
- Howell Latoya Lynette
- Howells Sally Lucinda
- Hsu Fan
- Hu George
- Hu Jie
- Hu Songnian
- Huang Fang
- Huang Guyang
- Huang Katherine
- Huang Mei
- Huang Wayne
- Huang Wei
- Huang Wei
- Huang Wei
- Huang Zhengping
- Hubbard Timothy
- Huber James W.
- Huckle Elizabeth
- Hue Heather
- Hughes Jaime
- Hughes Jennifer
- Hughes Lee
- Hughes-Hull Hillary
- Hull Louisa
- Hulme Bill
- Hulyk Steven
- Hume Jennifer
- Hummeric Holger
- Humphray Sean
- Humphries David
- Humphries Matthew
- Hunt Adrienne
- Hunt Michael
- Hunt Paul
- Hunt Sarah
- Hunter Giselle
- Hunter Rov, II
- Hupman Matt
- Huynh Sandy
- Hyde David
- Hynds Christopher
- Idlebird Devincent G.
- Iliev Ilian
- Imbro Paula
- Imo Kelvin C.
- Inacio Nicole
- Inagaki Naomi
- Ince Michael
- Ingram Drew
- Inoue Shuuji
- Isak Amber
- Isherwood Judith
- Ishibashi Akiko
- Ishikawa Sabine K.
- Ishizaki Hinako
- Isozaki Emi
- Israni Sanjay
- Ito Fumiaki
- Ito Noriko
- Itoh Takehiko
- Iwakawa Shinobu
- Iwatate Mariko
- Iwatsu Mikiko
- Iyer Vivek
- Izatt Janet
- Izmajlowicz Monica
- Izumiyama Tomohiro
- Jacintho Mark
- Jackson Laronda R.
- Jackson Terri
- Jacob Leni Susan
- Jaeger Sara
- Jaffe David B.
- Jahn Niels
- Jaklevic Joseph
- Jaklevic Michael
- James Kent W.
- Jareborg Niclas
- Jarek Michael
- Jassal Bijay
- Jeffery Grant
- Jeffery Kim
- Jeffrey Colin
- Jekosch Kerstin
- Jenkins Lee
- Jett Jamie
- Jewett Phillip E.
- Jia Jia
- Jia Jia
- Jia Nan
- Jia Xingchang
- Jiang Lu
- Jiang Yanrui
- Jiang Ziyou
- Jimenez Alberto
- Jin Jian
- Jin Yetao
- Jin Yongsan
- Johansen Tina
- Johnson Bennie
- Johnson Cheryl
- Johnson Christopher
- Johnson David
- Johnson Douglas
- Johnson Genevieve
- Johnson Lori
- Johnson Mark
- Johnson Philip
- Johnson Rudy
- Johnson Stephanie
- Jolivet Angela
- Jolley Keith
- Jones Abigail
- Jones Charlien
- Jones Claire
- Jones Juliet
- Jones Matthew
- Jones Michael
- Jones Micheil
- Jones Myrna D.
- Jones Steven
- Jong Pieter De
- Jordan Yun
- Joseph Shirin
- Joy Ann
- Joy Linsey
- Joy Victoria
- Joyce Gillian
- Jubb Mark
- Jung Eugine
- JĂ€rke Doris
- Kadner Kristen
- Kagan Ryan
- Kahsai Orsalem
- Kaida Kaoru
- Kale Pat
- Kalicki-Veizer Joelle
- Kamal Michael
- Kamat Asha
- Kamholz Sandra
- Kana Arnold
- Kang Hui
- Kang Kelie
- Kang Ning
- Kapur Hitesh
- Karolchik Donna
- Karunaratne Kanchi
- Kasprzyk Arek
- Katayama Takujiro
- Kato Takako
- Kauer Gerhard
- Kaul Rajinder
- Kaur Amardeep
- Kawagoe Chiharu
- Kawasaki Kazuhiko
- Kay Michael
- Kaye Danielle
- Kearney Lyndal
- Keefe Damian
- Keen Gifford
- Keenan Stephen
- Kegelmeyer Laura
- Kegg Lisa
- Kelley Simon
- Kells Cristyn
- Kelly Shayna P.
- Kelly Susan H.
- Kershaw Joanna
- Kettleborough Ross
- Keys David
- Khan Arsi
- Khan Umer F.
- Khan Ziad Mohid
- Khine Susu
- Khurama Divya
- Kidd Cathy
- Kierstan Peter
- Kieu Alix
- Kim Jennifer
- Kim Joomyeong
- Kim Kyung
- Kimball Heather
- Kimberley Andrew
- Kimura Moe
- King Andrew
- King Laquisha Monique
- King Mary-Clare
- Kingsley Simon
- Kingswood Colin
- Kisamo Haika
- Kisner Peter
- Kitts Paul
- Kiyooka Miho
- Klages Sven
- Klingle Gillian
- Knights Andrew
- Kobayashi Mai
- Kodira Chinnappa
- Kohlberg Sara
- Kojima Kazuyasu
- Kolbe William
- Kong Yi
- Korf Ian
- Kosiura Anna
- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
- Kremitzki Colin
- Kremmidiotis Gabriel
- Krogh Anders
- Kronmiller Brent
- Kruchowski Scott S.
- Kube Michael
- Kubischta Duane
- Kudoh Jun
- Kuehl Jennifer
- Kuharic Patrick
- Kuhn Carol
- Kulish Larissa
- Kuroki Yoko
- Kwan Chinnie
- Kyle Amy
- LaButti Kurt
- Lacombe Anne
- Lad Heena
- Lafrades Melanie
- Lagemann Dorothee
- Lai Jianghua
- Lai Teresa
- Laidlaw Philip
- Laing Michael
- Laird Gavin
- Lam Edward
- Lam Marissa
- Lama Dawa
- Lamar Betty
- Lambart Christine
- Lamble Ralph
- Lamerdin Jane E.
- Lander Eric S.
- Landers Tom
- Langford Cordelia
- Lansang Christine
- Lao Victoria
- Lapidus Alla
- Larke Ben
- Lato Bernadette
- Latreille Phil
- Lau Timun
- Lawlor Stephanie
- Layman Dan
- Leal Belita
- Leather Sampsa
- Lebow Heather
- Lee Byung-in
- Lee Cherie Jenae
- Lee Denise
- Lee Hong-Mei
- Lee Joon ho
- Lee Kenneth
- Lee Lisa
- Lee Peter
- Legall Fitzherbert Henderson, III
- Leger Jean Pierre
- Lehman Karl
- Lehmann RĂŒdiger
- Lehoczky Jessica
- Lehrach Hans
- Lehvaslaiho Minna
- Lei Meng
- Lemke Johannes
- Lennon Gregory
- Leonard Shawn
- Leonard Steven
- Leongamornlert Daniel
- Lesar Kendra
- Levan Jaclyn M.
- Leversha Margaret
- Levine Rosie
- Levy Andrew
- Levy Michaël
- Lewis Doreen
- Lewis Ernest K.
- Lewis Keith
- Lewis Lakeshia C.
- Lewis Lora R.
- Lewis Tammy
- Leyba Tina
- Li Changfeng
- Li Chenji
- Li Eryao
- Li Feifei
- Li Gang
- Li Jane
- Li Jiayang
- Li Jiayang
- Li Jihong
- Li Jing
- Li Jingfei
- Li Jingxiang
- Li Li
- Li Lili
- Li Lin
- Li Ming
- Li Nan
- Li Ran
- Li Shengbin
- Li Shuangding
- Li Shuangli
- Li Shuping
- Li Shuxia
- Li Songgang
- Li Tao
- Li Wei
- Li Zaiping
- Li Zhangwan
- Lieuallen Kim
- Lightning Julia
- Lim Meng K.
- Lindblad-Toh Kerstin
- Lindo Ken
- Lindquist K.
- Lindsay Sarah
- Lindstrom Kirsten
- LIne Matthew
- Ling Wei
- Linkowski Albert
- Linsdell Sally
- Little Peter
- Liu Boyong
- Liu Boyong
- Liu Cong
- Liu Dianwu
- Liu Haili
- Liu Jing
- Liu Jing
- Liu Jing Mei
- Liu Jun
- Liu Kai
- Liu Ning
- Liu Qian
- Liu Siqi
- Liu Stephanie
- Liu Wei
- Liu Wen
- Liu Xiaohong
- Liu Xinshe
- Liu Yanhua
- Liu Yannan
- Liu Yih-Shin
- Liu Yilin
- Liu Ying
- Liu Yu
- Liu Yu
- Liu Zhanwei
- Liyanage Dhammika
- Llewellyn-Silva Crystal
- Lloyd Christine
- Lloyd David
- Lobb Rebecca
- Lock Victoria
- Lock William
- Lodziak Anne
- Lokyitsang Tashi
- Lokyitsang Yeshi
- London Darin
- London Pamela
- Longden Ian
- Longmire Johnathan L.
- Lopez Frederick
- Lopez John
- Lopez Jose
- Lopez Lora
- Loraine Howard
- Lord Rachel
- Lorensuhewa Lorna M.
- Lou Yunian
- Loulseged Hermela
- Loveland Jane
- Lovell Jamie
- Lovett Demetria A.
- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
- Lu Tao
- Lu Xiuhua
- Lu Yongxiang
- Lu Yontao T.
- Lu Yue
- Lucas Robert
- Lucas Susan
- Lucier Alice
- Lucier Raymond L.
- Ludeman Thom
- Lui Annie
- Lundgren Lyndsey
- Luo Chunqing
- Luo Chunqing
- Lv Gang
- Lv Gang
- Lye Georgina
- Lynch Daniel
- Löhnert Tschong-Hun
- Ma Cheng
- Ma Gary
- Ma Jiao
- Ma Jie
- Ma Peter
- Ma Qingmei
- Ma Xiaohui
- Maas Jason
- Mabbitt Richard
- Macdonald Pendexter
- Machrus Migdad
- Macht Madison
- Macken Catherine A.
- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
- Maeda Hideto
- Maglott Donna
- Maheshwari Manjula
- Mahindartne Mathew
- Mahmoodi Venus
- Mahnke Ryan
- Mailey Brian
- Major John
- Malfatti Stephanie
- Malloy Kevin
- Maltbie Mary I.
- Mangum Brian
- Manning Jonathan
- Manohar Chitra
- Mapua Patricia
- Marabella Dick
- Mardis Elaine R.
- Mareth David
- Mariano Marisa
- Marinelli Lisa
- Mark Graham A.
- Marquis-Homeyer Catherine
- Marr Thomas G.
- Marra Marco
- Marriott Neil
- Marrone Anne
- Marroquin Christian
- Marsden Paul
- Marsh Victoria
- Martin Christopher
- Martin Joel
- Martin Kirt
- Martin Matthew
- Martin Sancha
- Martindale Ashley D.
- Martinez Diego
- Martinez Evangelina
- Martinez Michele
- Martinka Scott
- Maru Kebede
- Maruyama Kayo
- Maslen Gareth
- Mason Debbie
- Masood Hadi
- Massey Elizabeth
- Matsuda Fumihiko
- Matsumoto Shuko
- Matsushita Yoshitaka
- Matthews Charles D.
- Matthews Lucy
- Matthews Nick
- Matthews Paul
- Matthews Sterling D.
- Mauceli Evan
- Maunes Cynthia
- Maupin Rachel
- Mawhiney Samantha
- Maynard Madalynne
- McCann Owen
- McCarthy Megan
- McClay Joseph
- McCollum Craig
- McConnachie Louise
- McCormick Mary Kay
- McCready Paula
- McDonald Bill
- McDonald Louise
- McDowall Jennifer
- McGhee Tina
- McGuire Sarah
- McGurn Phil
- McKeown Carole
- McLaren Stuart
- McLay Kirsten
- McLean James
- McLellan Michael D.
- McLeod Michael P.
- McMurdo John
- McMurray Amanda
- McMurray Des
- McMurray Kimberly
- McMurray Kimberly L.
- McNinch Jenny
- McPherson John
- McPherson John D.
- McVicker Graham
- McWilliams Natalie
- Mead Kelly
- Meador Michael G.
- Medina Catherine
- Mehta Nalini
- Meidi Patrick
- Meier Elke
- Meincke Linda J.
- Mejima Mio
- Meldrim James
- Melsopp Craig
- Mendez Sylvia
- Meneus Louis
- Meng Shanshan
- Menuge Noel
- Mercado Christian
- Mercado George
- Mercado Iracema C.
- Mercer Simon
- Merritt Christina E.
- Mesirov Jill P.
- Metzker Michael Lee
- Meyer Rekha
- Meyer Rick
- Miah Asab
- Michaelis Evelyn
- Micklem Gos
- Mieczkowski Carl
- Mier Maggie
- Miguel Trini
- Mihalev Atanas
- Mihalkanin Danielle
- Mihova Tanya
- Miles Simon
- Mileur Mason W.
- Miller Christie
- Miller Donald
- Miller Nancy
- Milne Sarah
- Miner George R.
- Miner Sheri
- Miner Tracie
- Minja Emmanuel
- Minoshima Shinsei
- Minx Patrick J.
- Misra Monica
- Mistry Dippica
- Mistry Shailesh
- Mitchell Jake
- Mitchell Jeff
- Mitchell Teresa
- Mitina Sophia
- Mitsui Aki
- Mitsuyama Susumu
- Miyazawa Akemi
- Mlenga Val
- Mohabbat Farida
- Mohabbat Khatera
- Mohammadi Maryam
- Mohrenweiser Harvey
- Molina Christophe
- Monforte Joseph
- Montemayor Julie
- Montgomery Baize
- Montgomery Mishelle
- Mooney Paul
- Moore Madeline
- Moore Niki
- Moreland Andrea
- Morgan Jenna
- Morgan Margaret B.
- Morita Hiroko
- Morris Sidney
- Mortimore Beverly
- Morton Jerry
- Motoyama Ayuko
- Mott Richard
- Moyzis Robert K.
- Mu Feng
- Mukherjee Shibani
- Mullenger Ian
- Mullikin Jim
- Mulrain Leon
- Munday Brian
- Munday Elaine
- Mundt Mark O.
- Mungall Andy
- Munidasa Mala
- Munk A. Christine
- Munk Christie A.
- Munson Glen
- Murakami Katsuhiko
- Murayama Yuji
- Murnane Clare
- Murphy Matthew B.
- Murphy Michael
- Murray Christine
- Murray Debra Dianne
- Murray Jennifer
- Murrell Kerry
- Muzny Donna Marie
- Myers Alison
- Myers Richard
- MĂŒller Ines
- Nagamine Kentaro
- Nagao Syunsuke
- Nagaraja R.
- Nair Latha
- Nair Seema R.
- Naka Maho
- Nakagawa Masayo
- Nakagawa Saori
- Nakamura Etsuko
- Nakato Eriko
- Nanavati Amit N.
- Nandkeshwar Richard
- Nankervis Colin E.
- Naranjo Cleo M.
- Nash William
- Naylor Jerome
- Nazareth Lynne V.
- Neal Dearl D.
- Negus David
- Nelson Catherine
- Nelson David O.
- Nelson Deborah A.
- Nelson Joanne
- Nelson Kathryn
- Nelson Ward
- Nesbitt Ryan
- Neunkirch Jennifer
- Newes Christian
- Newman April
- Ng Bee
- Ng Terrance
- Ngo Robin Ngoc
- Nguyen Bao-Viet
- Nguyen Christine
- Nguyen Cindy
- Nguyen Hoa
- Nguyen Le-Thu Dinh
- Nguyen Lisa
- Nguyen Minh
- Nguyen Na
- Nguyen Natalie M.
- Nguyen Ngoc Bich
- Nguyen Thu
- Nhan Mike
- Ni Lin
- Niblett David
- Nicholson Jonathan
- Nickerson Elizabeth
- Nickerson Tim
- Nicol Robert
- Nijjar Sukhjit
- Ning Zemin
- Nisbet James
- Nishida Aki
- Niu Yuxin
- Niu Yuxin
- Nivens Amber
- Noguchi Hideki
- Nolan Matt
- Norbu Chou Dolma
- Norbu Nyima
- Nordsiek Gabriele
- Norris Sarah Louise
- Novik Karen
- Nowlin Larry
- Nusbaum Chad
- Nwaokelemeh Ogechi O.
- Nwokenkwo Stanley
- O\u27Donnell Paula
- O\u27Donovan Daniel
- O\u27Leary Sinead
- O\u27Loughlin Jennifer
- O\u27Neill Keith
- Obayashi Izumi
- Obregon Melissa
- Oddone Paola
- Oddone Pierre
- Oddy Lachlan
- Odell Christopher
- Ogawara Etsuko
- Ogbighele Francess
- Oguh Maryann
- Ohmori Kyoko
- Ohno Saho
- Ohta Nao
- Ohtsubo Masafumi
- Oinn Tom
- Okoawo Ose
- Okui Michiyo
- Okumura Reina
- Okwuonu Geoffrey O.
- Okwuonu Kenneth C.
- Olarnpunsagoon Alisa
- Olivas Jason
- Oliver Hayley
- Oliver Karen
- Olsen Anne S.
- Olson Maynard V.
- Omotosho Bamidele
- Onoda Junko
- Oomori Nobuhiro
- Ooshima Kenshiro
- Oragunye Njideka
- Orantes Jerry
- Orbell Helena
- Osada Misuzu
- Osborn Anthony
- Osborne Joan
- Osman Sahal
- Ovcharenko Ivan
- Overton-Larty Emma
- Oviedo Rodolfo J.
- Ow David
- Ozawa Ritsuko
- Ozersky Philip
- Pace Araceli C.
- Pack Elizabeth
- Padki Anuradha
- Pahlavan Shane
- Palaniappan Krishnaveni
- Palazzolo Michael
- Palmeiri Anthony
- Palmer Sophie
- Pan Jiaofeng
- Pan Sisu
- Panasenko Vladimir
- Pandian Richard
- Parker Adrian
- Parker David Neil
- Parker Stephen
- Parkin Christopher
- Parkin Kim
- Parks Kenya L.
- Parry-Brown Ginny
- Parson-Quintana Beverly
- Pasternak Shiran
- Patel Bella Mayurkumar
- Patel Dina
- Patel Jalpa N.
- Patel Ritesh
- Patel Shripa
- Patel Vishal V.
- Patrick James
- Paul Heidie A.
- Paul Shelia
- Paulson Edward
- Payton Brett A.
- Pearce Alexandra
- Pearman Charlene
- Pearson Danita
- Pecherer Robert M.
- Peck Anna
- Peck Richard
- Pedan John
- Pelan Sarah
- Pelletier Eric
- Peng Vivian
- Peng Vivian
- Peng Yi
- Peng Yi
- Peng Ze
- Peng Ze
- Pennacchio Len A.
- Pennacchio Len A.
- Percy Chantel
- Perez Agapito
- Perez Lesette M.
- Perito Andrew
- Perrault Isabelle
- Perrier Rene
- Perrier Rene
- Perrin William
- Pesavento Brad
- Peters Anna
- Peters Leonard G.
- Peterson Jane
- Peterson Karl
- Petit Jean-Louis
- Pettett Roger
- Petz Uta
- Pfeiffer Joyce
- Phan Hoan
- Phelps Karen
- Phillimore Ben
- Phillips Kim
- Phillips Samantha
- Phulchung Tenzin
- Phunkang Pema
- Pickens Adam
- Pieper Natasha
- Pierre Nadia
- Piqani Bruno
- Piscia C.
- Pitesky Maurice
- Pitluck Sam
- Plajzer-Frick Ingrid
- Platt Darren
- Platzer Matthias
- Playford Emma
- Plopper Farah Jo Homsi
- Plumb Bob
- Pocock Matthew
- Pohl Craig
- Poindexter Alan
- Poliakov Alex
- Pollard Martin
- Polman Jos
- Ponting Chris P.
- Porter Aaron
- Porter Keith
- Porter Tarryn
- Posada Martha
- Potter Christopher
- Potter Simon
- Poundstone Pat
- Pourrajabi Nima M.
- Powell Don
- Powell Jason
- Prado Daisy
- Prange Christa
- Prathalingham Radhika
- Predki Paul
- Prigmore Elena
- Primus Eltrick L.
- Primus Jennifer
- Probst Lyle
- Procter Glenn
- Pruitt Kim
- Pu Ling-Ling
- Puazo Maria
- Putnam Nicholas
- Qasem Osama
- Qi Qiuhui
- Qi Xiaohua
- Qi Xiaohua
- Qian Xufang
- Qian Zengmin
- Qiang Boqin
- Qiang Boqin
- Qiao Zhenyong
- Qin Xiang
- Quail Michael
- Quan Glenda
- Quarrie Hannah
- Quiles Miyo M.
- Quince Chris
- Quiroz Juana B.
- Qureshi Matloob
- Rabata Dina
- Rachlin Eric K.
- Rachupka Anthony
- Radionenko Maxim
- Rajagopal Mohan
- Ramasami Umadevi
- Rameau Rayale
- Ramirez Lucia
- Ramirez Melissa
- Ramos Nicole
- Ramsay Helen
- Ramsey Yvonne
- Ranby Sally
- Rance Richard
- Rand Vikki
- Randall-Maher Jennifer
- Randolph David
- Randolph James
- Rapier Irma
- Rappaport Barry
- Rash Sam
- Ratford Joanne
- Ratford Lewis
- Ratliff Robert I.
- Ray Aditya
- Ray Vernada
- Raymond Chris
- Raymond Christina
- Read Daniel
- Redhead Donald
- Redon Richard
- Rees Christine
- Reeves Kacy
- Regala Warren
- Reichwald Kathrin
- Reid Mary
- Reigh Richard A.
- Reily Amy D.
- Reinhardt Astrid
- Reinhardt Richard
- Reiter Charlie
- Ren Shuangxi
- Ren Shuangxi
- Ren Yanru
- Retterer James
- Rice Alex
- Rice Catherine
- Rice Peter
- Rice Stephen
- Richard Suzzanne
- Richards Stephen
- Richardson Kristi
- Richardson Paul
- Richardson Paul
- Richardson Susan
- Ricke Darryl O.
- Ridler Kerry
- Riethman Harold
- Riethoven Lyn
- Rigby Rachel
- Riley B.E
- Rise Cecil
- Rivera Angel
- Rives Catharine M.
- Road JungShing
- Robert Catherine
- Roberts Simon
- Robinson Chris
- Robinson Dezere
- Robinson Donna I.
- Robinson Donna L.
- Robinson Melanie
- Rochford Rebecca
- Rock Susan M.
- Rodkey Travis L.
- Rodriguez Alex
- Rodriguez Joseph
- Rodriguez Juan
- Rogers Jane
- Rogers Lisa
- Rogers Stephanine
- Rogosin Andrea
- Rogov Peter
- Rohlfing Theresa
- Rojas Alberto
- Rokhsar Daniel
- Rong Li
- Rong Li
- Rosenbloom Kate R.
- Roskin Krishna M.
- Ross Hugh
- Ross Mark
- Ross Stephanie
- Rowen Lee
- Rubenfield Marc
- Rubin Edward M.
- Ruef Barbara
- Ruiz Erica M.
- Ruiz San Juana
- Rule Angela
- Rule James
- Rule Jeffrey
- Russell Ben
- Russell Jayne
- Ryan Andrea
- Sabo Aniko
- Saenphimmachak Channakhone
- Safdar Kamal
- Sakai Ryoko
- Sakaki Yoshiyuki
- Sakaldasis George
- Salamov Azaf
- Salazar Angelica
- Salter Natalie
- Samain Sylvie
- Sana Moazzam Mohammad
- Sanders Brent
- Sanders Christina
- Sanders Wendi
- Santibanez Jireh
- Santoyo-Lopez Javier
- Sanuki Naoko
- Sarmiento R.
- Sasaki Takashi
- Satpathy Suraj
- Saunders David
- Saunders Elizabeth H.
- Saurin William
- Savery Glenford G.
- Sawada Nori
- Sawhill William W.
- Saxman Eric
- Scarpelli Claude
- Scharfe Maren
- Schatzkamer Kyriena L.
- Scherer Steven Edward
- Schilhabel Markus
- Schlessinger David
- Schmeits James
- Schmidt Esther
- Schmoger Siliva
- Schmutz Jeremy
- Schnabl Matthew
- Schuler Gregory
- Schupbach Rebecca
- Schuster Michael
- Schön Oliver
- Scott Carol
- Scott Damian
- Scott Deborah
- Scott Duncan
- Scott Graham
- Scott Ian
- Scott Kelsi
- Scott Paul
- Seager Fiona
- Seaman Christopher
- Seaman Steven
- Searle Margaret
- Searle Paul
- Searle Stephen
- Sehra Harminder
- Seitz Kathleen
- Sekhon Mundeep
- Severin Jessica
- Seymour Burt
- Shah Neha
- Shakespeare Joe
- Shams Saima
- Shao Chunyan
- Shao Yufen
- Shapiro Harris
- Shardelow Jason
- Sharp Greg
- Sharpe Ted
- Shaw Teresa
- Shaw-Smith Charles
- She Xinwei
- Shearing Jennifer
- Shen Fengye
- Shen Hua
- Shen Meishan
- Shen Yan
- Shen Yan
- Shen Yan
- Sheng Haihui
- Sheppard Karen
- Sheridan Andrew
- Sheridan Elizabeth
- Sherpa Ngawang
- Shi Guibin
- Shi Hongfang
- Shibuya Kazunori
- Shiino Noriko
- Shimizu Atsushi
- Shimizu Hidetsugu
- Shimizu Nobuyoshi
- Shimizu Yoshiko
- Shin Maria
- Shindoh Nobuaki
- Shintani Ai
- Shiohama Aiko
- Shoji Minami
- Shotland Yoram
- Shought Timothy
- Shownkeen Ratna
- Shreve Jeff
- Siddiqui Roman
- Siepel Adam C.
- Silk Richard
- Silk Richard
- Sims Matthew
- Sims Matthew
- Sims Sarah
- Sims Sarah
- Sindelar Linda
- Sinha Prashant
- Sisson Ida
- Sivadasan Shanthi
- Sivadasan Shanthi
- Skowronski Evan
- Skuce Carl
- Skuce Carl
- Slater Nathaniel
- Slezak Tom
- Smedley Damian
- Smink Luc
- Smink Luc
- Smith Andrew
- Smith Andrew
- Smith Cherylyn
- Smith Doug
- Smith Douglas R.
- Smith James
- Smith James
- Smith Joel
- Smith Karen
- Smith Laura
- Smith Laura
- Smith Lorraine
- Smith Lorraine
- Smith Michael
- Smith Michelle
- Smith Michelle
- Smith Russell
- Smith Russell
- Smith Stephanie
- Smith Stephanie
- Smith Troy
- Sneath Hannah
- Sneath Hannah
- Sodergren Erica
- Soderlund Cari
- Soderlund Cari
- Soderlund Cari
- Solovyev Victor
- Solovyez Victor
- Sonaike Titilola
- Song Liping
- Song Liping
- Song Shuping
- Song Xing-Zhi
- Sonnhammer Erik
- Sonnhammer Erik
- Sorelle Richard P.
- Sotheran Elizabeth
- Sougnez Carrie
- Spainhower Corey
- Sparks Anastasia L.
- Spencer Brian
- Spieth John
- Spooner William
- Spraggon Lee
- Sqaures Suzanna
- Squares Janet
- Stabenau Arne
- Stables Michael
- Stalker James
- Stalker John
- Stallings Raymond I.
- Stalvey Malinda
- Stamford Steve
- Stammers Melanie
- Standring Lisa
- Stange-Thomann Nicole
- Stavropoulos Sharon
- Steffen David
- Stege Justin T.
- Steingruber Helen
- Stephens Yvonne
- Stephens-Bolds Shaela
- Stetson Kevin
- Stevko Victor
- Steward Charles
- Stewart Aengus
- Stewart Michael
- Still Ian
- Stock Mo
- Stone Casey
- Stone Evan
- Stone Sabrina
- Stoppard Lisa
- Storey Philip
- Storey Roy
- Stowe Sarah
- Strachan Carol
- Strachan Greg
- Strasser Jonathan
- Stribling Claire
- Strong Cynthia
- Stubbs Lisa
- Stubbs Matthew
- Stultz Janet
- Sturdy John
- Su Xiaohu
- Subramanian Sandhya
- Subramanian Sandhya
- Sudbrak Ralf
- Sugnet Charles W.
- Sulston John
- Summers Leslie J.
- Sun Hui
- Sun Jiajia
- Sun Jiandong
- Sun Jiu Qin
- Sun Min
- Sun Tao
- Sun Wei
- Sun Yongqiao
- Sun Yu
- Sun Yue
- Sutherland Grant R.
- Sutherland Robert D.
- Sutton Angelica E.
- Svatek Amanda F.
- Svetz Jessica
- Svetz Leah Anne
- Swainson Chris
- Swann Mark
- Swarbreck David
- Swearengen-Shahid Sharhonda
- Sycamore Neil
- SĂ©gurens BĂ©atrice
- Tabor Paul E.
- Tacey Kristina
- Tagett Beckie
- Tagney Matthew
- Tahara Takashi
- Takahashi Keiko
- Takano Nobuhiro
- Takaoka Tori
- Takayanagi Atsushi
- Takenaka Tracy
- Talamas Jessica
- Tam Serena
- Tamerisa Kavitha S.
- Tamirisa Aparna
- Tan Olivia
- Tan Steven
- Tan Xinyu
- Tan Xinyu
- Tang Hongli
- Tang Xiangjun
- Tansey Jennifer
- Tao Ran
- Tapia Roxanne
- Taring Elizabeth
- Tatsuyama Miho
- Tatum Owatha I.
- Taudien Stefan
- Taylor Amy
- Taylor Christina C.
- Taylor Gillian
- Taylor Kate
- Taylor Ruth
- Taylor Sam
- Taylor Susan
- Taylor Tineace R.
- Taylor Todd Duane
- Tchuinga Pierre
- Tee Louise
- Telford Ethan Brett
- Tenzin Pema
- Terada Yoriko
- Terry Astrid
- Tesfaye Senait
- Tesmer Judith G.
- Tester Julieanne
- Thayer Nina
- Theaker Andrew
- Theil James
- Theodore Joumathe
- Thexton David
- Thies Stephanie
- Thomas Craig
- Thomas Daniel
- Thomas Daryl J.
- Thomas Karen
- Thomas Nicole
- Thomas Paulette
- Thomas Ruth
- Thomas Shereen
- Thommai Roselin
- Thompson Linda S.
- Thorne Rachel Diane
- Thorpe Andrea
- Thorpe Karen
- Thoulutsang Yama
- Threadgold Glen
- Thurston Scott
- Tian Chaoguang
- Tian Chaoguang
- Tian Wei
- Tian Yan
- Tian Yong
- Tian Yuqing
- Tice Hope
- Tighe Damon
- Tin-Wollam Aye M.
- Tinsley Emma
- Tochigi Miwako
- Togashi Naoko
- Tomizawa Iori
- Tomlinson Chad
- Tong Jingli
- Topham Kerri
- Torcaso Bill
- Torney David C.
- Totoki Yasushi
- Towey Sarah
- Toyoda Atsushi
- Tracey Alan
- Tran Ly Thanh
- Tran-Gyamfi Mary
- Trani Lee
- Trankiem Margie
- Trask Barbara J.
- Travers Johnathan
- Trejos Zulma Y.
- Treuhaft Marianne
- Trevino Brenda Kaye
- Tromans Anthony
- Trong Stephan
- Trumbower Heather
- Tsai Ming
- Tsamla Tsamla
- Tsolas Jason
- Tsomo Nawang
- Tsujimoto Susan
- Tsukamoto Yumi
- Tsuruoka Hiromi
- Tsuzuki Rina
- Tu Yuefeng
- Tu Yuefeng
- Tubby Ben
- Tufarelli Cristina
- Turner Heidi
- Turney Kathryn
- Tynan Katherine
- Ueland Stephanie
- Ueng Samantha
- Ukegbu Ogechi Nkemdirim
- Ulanovsky Levy E.
- Un Chun
- Ung Quyen
- Upson Darren
- Urban Jeremy B.
- Ureta-Vidal Abel
- Ureta-Vidal Abel
- Usmani Kamran
- Ustaszewska Anna
- Uyama Nozomi
- Valas Ruben E.
- Valdez Michelle
- Valle Duane
- Valles Yvonne
- Van Brunt Andrew
- Van Dilla Marvin
- Van Helmond Zoe
- Van Luchene Ryan
- Vardanian Zachary
- Vargas Michelle
- Vargo Charles E.
- Vartanian Steffan
- Vasquez Lydia I.
- Vassiliev Helen
- Vastrik Imre
- Vaudin Mark
- Veil Rose
- Veklerov Eugene
- Velasco Nelson
- Velasquez Lisa
- Venkataranan Vijay
- Vera Virginia A.
- Verduzco Daniel
- Vergez Lisa
- Vico Virginie
- Viknaraja Ramya
- Villasana Donna M.
- Vine Wendy
- Viswanathan Vijay
- Vo Andy
- Vo Nu
- Voak Paul
- Vollenhoven David
- Wada Hiromi
- Wagner Mark
- Wagner-McPherson Caryn
- Waldron Lenee
- Waligorski Jason E.
- Walker Davian L.
- Walker Keya
- Walker Sarah
- Wall Melanie
- Wall Randy E.
- Wallace John
- Wallis Justine
- Wallis Michelle
- Walsh Jennifer
- Walsham Natalie
- Wan Ma
- Wang Chunyan
- Wang Dong
- Wang Feng
- Wang Guangxin
- Wang Guihai
- Wang Guihai
- Wang Hongjuan
- Wang Hongwei
- Wang Huanjie
- Wang Huifeng
- Wang Huifeng
- Wang Jian
- Wang Jian
- Wang Jian
- Wang Jie
- Wang Jing
- Wang Jingqiang
- Wang Jingqiang
- Wang Jinhua
- Wang Joann
- Wang Juan
- Wang Jun
- Wang Jun
- Wang Jun
- Wang Li
- Wang Lijie
- Wang Lijuan
- Wang Lijun
- Wang Ling
- Wang Liqun
- Wang Mei
- Wang Qiaoyan
- Wang Shifen
- Wang Shu
- Wang Suzhen
- Wang Wenjun
- Wang Xiaoling
- Wang Xiaoning
- Wang Xuefei
- Wang Xuegang
- Wang Yan
- Wang Yimin
- Wang Ying
- Wang Ying
- Wang Yuanyuan
- Wangchuck Tsering
- Wangdi Tsering
- Ward-Moore Stephanie
- Warren Graham
- Warren James T.
- Warry Georgina
- Watanabe Hidemi
- Watanabe Saki
- Waterston Robert H.
- Watson Andy
- Watt Nicola
- Webb Anthony
- Webb Jeannette
- Webber Caleb
- Weber Ryan J.
- Wehri Edward
- Wei Shulin
- Wei Xuehong
- Weidenbach Richard
- Weinstock George
- Weinstock Keith
- Weir John
- Weissenbach Jean
- Wells Alan
- Wells Sarah
- Welton Robert
- Wen Gaiping
- Wendi Mike
- Weng Li
- Wenning Sarah
- Wentz Sara
- Werler Daniela
- Wesley Mary Melissa
- West Paul
- West Tony
- Wetterstrand Kris
- Wheatley Angela
- Wheatley Carl
- Wheeler David A.
- Wheeler Gideon
- Wheeler Jeremy
- Whitaker Hayley
- White Adam
- White Amelia
- White Brian
- White Catherine
- White Flower
- White Jennifer
- White Johnathon
- White P. Scott
- White Scott P.
- White Simon
- Whitehead Sally
- Whiteley Matthew
- Whitmore Scott
- Whittaker Adam
- Whittaker Charles
- Whittaker Pamela
- Wickremasinghe Manosha I.
- Widaa Sara
- Wiegel Sarah
- Wild Anna
- Wilkinson Jane
- Wilkinson Jane
- Wilkinson Paul
- Willey David
- Williams Albert L.
- Williams Andy
- Williams Bill
- Williams Gabrielle A.
- Williams Leanne
- Williamson Angela L.
- Williamson Helen
- Wills Patricia L.
- Wills Richard
- Wilmer Tamsin
- Wilming Laurens
- Wilson Brian
- Wilson Gareth
- Wilson Margaret
- Wilson Nyree
- Wilson Piers
- Wilson Richard K.
- Wilson Siobhan
- Wilson Steve
- Wilson Wendy
- Wincker Patrick
- Window Philip
- Winster Jenny
- Winzar Claire
- Witt James
- Wleczyk Regina
- Wobus Fred
- Woessner Jeffrey
- Wohldmann Patty
- Wollard Jessica
- Womack Andrew W.
- Wong Benjamin
- Wong Gane K-S
- Wood Diane
- Wood Emma
- Wood Joe
- Wooden Hailey S.
- Wooden Steven H.
- Woodeson Sharon
- Woodfine Kathryn
- Woodmansey Rebecca
- Woods Eric
- Woodwark Cara
- Wooster Richard
- Worley Kim Carlyle
- Woyke Tanja
- Wray Matthew
- Wray Paul
- Wright Charmain
- Wright Debbie
- Wright Kathrine
- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
- Wu Jiaqian
- Wu Jung-Rung
- Wu Kevin
- Wu Qingfa
- Wu Qingfa
- Wu Ruiming
- Wu Xiao
- Wu Xiaojing
- Wu Zaining
- Wyatt Julia
- Wycoff-Montenegro Melissa
- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
- Xie Fei
- Xie Gary
- Xie Jane
- Xiong Hui
- Xiong Yuqing
- Xu Alex
- Xu Jing
- Xu Jing
- Xu Ruqin
- Xu Shuhua
- Xu Wei
- Xu Xinlai
- Xu Yan
- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
- Yang Joan
- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
- Yokobata Kathy
- Yokoyama Jennifer
- Yonezawa Miho
- Yoon Lillienne
- Yoon Vivienne
- Yoshida Satoru
- You Bo
- Young Geneva
- Young Louise
- Young Shelia
- Younger Ruth
- Yu Bing
- Yu Charles
- Yu Fuli
- Yu Jun
- Yu Jun
- Yu Jun
- Yuan Kaiwen
- Yuan Ye
- Yuan Yida
- Yue Shujie
- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers âŒ99% of the euchromatic genome and is accurate to an error rate of âŒ1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Recommended from our members
Analyses of pig genomes provide insight into porcine demography and evolution
- Author
- Ahn Hyeonju
- Aken Bronwen L.
- Anselmo Anna
- Anthon Christian
- Archibald Alan L.
- Auvil Loretta
- Badaoui Bouabid
- Beattie Craig W.
- Bendixen Christian
- Berman Daniel
- Blecha Frank
- Blomberg Jonas
- Bolund Lars
- Bosse Mirte
- Botti Sara
- Bujie Zhan
- Bystrom Megan
- Caccamo Mario
- Capitanu Boris
- Carvalho-Silva Denise
- Chardon Patrick
- Chen Celine
- Cheng Ryan
- Choi Sang-Haeng
- Chow William
- Churcher Carol
- Clark Richard C.
- Clee Christopher
- Crooijmans Richard P. M. A.
- Dawson Harry D.
- De Sapio Fioravante
- Dehais Patrice
- Dibbits Bert
- Drou Nizar
- Du Zhi-Qiang
- Eversole Kellye
- Fadista JoĂŁo
- Fairley Susan
- Faraut Thomas
- Faulkner Geoffrey J.
- Fowler Katie E.
- Frantz Laurent A. F.
- Fredholm Merete
- Fritz Eric
- Gilbert James G. R.
- Giuffra Elisabetta
- Gorodkin Jan
- Griffin Darren K.
- Groenen Martien A. M.
- Harrow Jennifer L.
- Hayward Alexander
- HornshĂžj Henrik
- Howe Kerstin
- Hu Zhi-Liang
- Humphray Sean J.
- Hunt Toby
- Jeon Jin-Tae
- Jern Patric
- Jones Matthew
- Jurka Jerzy
- Kanamori Hiroyuki
- Kapetanovic Ronan
- Kim Heebal
- Kim Jae-Hwan
- Kim Jaebum
- Kim Kyu-Won
- Kim Tae-Hun
- Larkin Denis M.
- Larson Greger
- Lee Kyooyeol
- Lee Kyung-Tai
- Leggett Richard
- Lewin Harris A.
- Li Shengting
- Li Yingrui
- Liu Wansheng
- Loveland Jane E.
- Lu Yao
- Lunney Joan K.
- Ma Jian
- Madsen Ole
- Mann Katherine
- Matthews Lucy
- McLaren Stuart
- Megens Hendrik-Jan
- Milan Denis
- Morozumi Takeya
- Murtaugh Michael P.
- Narayan Jitendra
- Ni Peixiang
- Oh Song-Jung
- Onteru Suneel
- Panitz Frank
- Park Chankyu
- Park Eung-Woo
- Park Hong-Seog
- Pascal Geraldine
- Paudel Yogesh
- Perez-Enciso Miguel
- Ramirez-Gonzalez Ricardo
- Reecy James M.
- Rodriguez-Zas Sandra
- Rogel-Gaillard Claire
- Rogers Jane
- Rohrer Gary A.
- Rothschild Max F.
- Rund Lauretta
- Sang Yongming
- Schachtschneider Kyle
- Schook Lawrence B.
- Schraiber Joshua G.
- Schwartz John
- Scobie Linda
- Scott Carol
- Searle Stephen
- Servin Bertrand
- Southey Bruce R.
- Sperber Goran
- Stadler Peter
- Sweedler Jonathan V.
- Tafer Hakim
- Takeuchi Yasuhiro
- Thomsen Bo
- Truong Nguyen Dinh
- Tuggle Christopher K.
- Uenishi Hirohide
- Wali Rashmi
- Wang Jian
- Wang Jun
- White Simon
- Xu Xun
- Yerle Martine
- Zhang Guojie
- Zhang Jianguo
- Zhang Jie
- Zhao Shuhong
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
For 10,000âyears pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars âŒ1 million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation. Genes associated with immune response and olfaction exhibit fast evolution. Pigs have the largest repertoire of functional olfactory receptor genes, reflecting the importance of smell in this scavenging animal. The pig genome sequence provides an important resource for further improvements of this important livestock species, and our identification of many putative disease-causing variants extends the potential of the pig as a biomedical model
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission
- Author
- Aanensen David M.
- Abell Chris
- Abudahab Khalil
- Acheson Erwan
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Aggarwal Dinesh
- Ahmad Shazaad S. Y.
- Ahmadi-Assalemi Gabriela
- Aigrain Louise
- Alam Mohammad T.
- Alcolea-Medina Adela
- Alderton Alex
- Alikhan Nabil-Fareed
- Allara Elias
- Amato Roberto
- Andersson Monique
- Angelis Daniela De
- Angelis Daniela De
- Angyal Adrienn
- Aranday-Cortes Elihu
- Ariani Cristina V.
- Asad Hibo
- Asamaphan Patawee
- Ash Amy
- Ashcroft Fiona
- Atkinson Laura
- Attwood Stephen W.
- Auckland Cressida
- Awan Ali R.
- Aydin Alp
- Baker David J.
- Baker Paul
- Balcazar Carlos E.
- Ball Jonathan
- Barrett Jeff
- Barton Edward
- Bashton Matthew
- Bassett Andrew R.
- Batra Rahul
- Baxter Laura
- Bayzid Nadua
- Beale Mathew A.
- Beaver Charlotte
- Beckett Angela H.
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellis Katherine L.
- Berry Lisa
- Berry Louise
- Berry Sarah
- Best Angus
- Betancor Gilberto
- Betteridge Emma
- Bewshea Claire M.
- Bibby David
- Bicknell Kelly
- Birchley Alec
- Bird Paul
- Bishop Chloe
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- BoYes John
- Bradley Amanda
- Bradley Declan T.
- Bradshaw Daniel
- Braithwaite Vickie
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgewater Hannah E.
- Brierley Craig
- Bronner Iraad F.
- Brooks Ellena
- Broos Alice
- Brown Christopher
- Brown Christopher A.
- Brown Julianne R.
- Brown Nicholas M.
- Brown Paul E.
- Brown Rebecca
- Bucca Giselda
- Buck David
- Bull Matthew
- Burton-Fanning Shirelle
- Campbell Sharon
- Carabelli Alessandro M.
- Carden Holli
- Carlile Matthew
- Carmichael Stephen N.
- Casey Anna
- Caspersz Michelle
- Ceaser Matt
- Cerda Alberto C.
- Chalker Vicki
- Chand Meera
- Chapman Michael H. S.
- Chapman Michael R.
- Chappell Joseph G.
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Afzal
- Chaudhry Yasmin
- Chauhan Anoop J.
- Cheng Jeffrey K. J.
- Churcher Carol M.
- Clark Gemma
- Clark Roger
- Clarke Rebecca
- Cogger Benjamin J.
- Coll Francesc
- Collins Jennifer
- Connor David
- Connor Thomas R.
- Constantinidou Chrystala
- Cook Kate
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nick
- Cotic Marius
- Cottrell Simon
- Coupland Lindsay
- Cowell Angela
- Cox Alison
- Craine Noel
- Crawford Liam
- Cronin Michelle
- Crook Derrick
- Crowcroft Jon
- Cumley Nicola
- Curran Martin D.
- Curran Tanya
- da Silva Filipe Ana
- Dabrera Gavin
- Dadrah Ashok
- Dahal Aastha
- Danaei Darius
- Danesh John
- Darby Alistair C.
- Davidson Rose K.
- Davies Alisha
- Davies Richard
- Davies Robert
- Davis Thomas
- de Cesare Mariateresa
- de Oliveira Martins Leonardo
- de Silva Thushan I.
- Debebe Johnny
- Dent Hannah
- Dervisevic Samir
- Dewar Rebecca
- Dhada Maharshi
- Dias Joana
- Dorman Matthew J.
- Dougan Gordon
- Douthwaite Julie
- Downing Fatima
- Drury Eleanor
- du Plessis Louis
- du Plessis Louis
- Duckworth Nichola
- Durham Jillian
- Dyer Rory
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Ellard Sian
- Elliott Scott
- Eltringham Gary
- Emanuela P.
- Enright Jessica
- Ensell Leah
- Essex Sarah
- Evans Cariad
- Evans Johnathan M.
- Eyre David
- Fairley Derek J.
- Fallon Karlie
- Farbos Audrey
- Farr Ben W.
- Fatseas Tania
- Faulkner Kathryn
- Fearn Christopher
- Feather Tom
- Feltwell Theresa
- Fenton Melisa L.
- Ferris Mark
- Fieldman Thomas
- Fina Laia
- Fisher Chloe L.
- Flaviani Flavia
- Fleming Vicki M.
- Forrest Sally
- Foulser Luke
- Francois Sarah
- Fraser Christophe
- Freeling Anthony
- Freeman Timothy M.
- Frost Lucy R.
- Fuller Stewart
- Fuller William
- Galai Katerina
- Gallagher Eileen
- Gallagher Michael D.
- Gallis Marta
- Gaskin Amy
- Gatica-Wilcox Bree
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P.
- Georgiou Christine
- Gibbs Karen
- Gifford Laura
- Gilbert Lauren
- Gill Harmeet K.
- Girgis Sophia T.
- Glaysher Sharon
- Glew Rob
- Glover Michael
- Golubchik Tanya
- Goncalves Sonia
- Goodall Robin
- Goodfellow Ian
- Goodfellow Ian G.
- Goodwin Scott
- Goudarzi Salman
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Grammatopoulos Dimitris
- Gransden Lucie
- Greatorex Jane
- Green Angie
- Green Luke R.
- Greenaway Jane
- Gregory Richard
- Groves Danielle C.
- Groves Natalie
- Guest Martyn
- Gulliver Huw
- Gunson Rory N.
- Gupta Ravi K.
- Gutierrez Bernardo
- Hadjirin Nazreen F.
- Haldenby Sam T.
- Hale Antony D.
- Hall Grant
- Halstead Fenella
- Hamilton William L.
- Hamilton William L.
- Hamilton William L.
- Hancock Dawn
- Hannan Sophie
- Haque Tanzina
- Harper Katherine L.
- Harris Kathryn A.
- Harrison Ewan M.
- Harrison Ian
- Harrison James W.
- Hart Jennifer
- Hartley John A.
- Hartman Hassan
- Hassan-Ibrahim Mohammed O.
- Heaney Judith
- Helmer Thomas
- Henderson Robert
- Hesketh Andrew R.
- Heyburn David
- Higginson Ellen E.
- Hilborne Sarah
- Hill Verity
- Hilvers Ember
- Hiscox Julian A.
- Hoensch Steve
- Hogsden Wendy
- Holden Matthew T. G.
- Holgate Jon
- Hollamby Victoria
- Holmes Alison
- Holmes Christopher
- Holmes Nadine
- Hopes Richard
- Hosaja Aleksandra
- Hosmillo Myra
- Hosmillo Myra
- Howe Robin
- Howes Rob
- Howson-Wells Hannah C.
- Hubb Jonathan
- Hughes Gareth J.
- Hughes Joseph
- Hughes Margaret
- Hughes Robert
- Hunt Martin
- Hutchings Stephanie
- Illingworth Chris
- Illingworth Chris J.
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Izuagbe Rhys
- Jackson Chris
- Jackson David K.
- Jackson Kathryn A.
- Jahun Aminu
- Jahun Aminu S.
- James Keith
- James Laura
- Jamrozy Dorota
- Jannoo Riaz
- Jeffries Aaron R.
- Jeremiah Sarah
- Jesudason Natasha G.
- John Michaela
- Johnson Dean
- Johnson Kate
- Johnson Natasha
- Johnson Rob
- Johnston Ian
- Jones Carl
- Jones Christopher R.
- Jones Daniel R.
- Jones Hannah
- Jones Katie
- Jones Rachel
- Jones Sophie
- Jordan Sinead
- Jorgensen David
- Joseph Amelia
- Justice Anita
- Kahkeshi Mahin Bagheri
- Kane Leanne
- Karamani Angeliki
- Kay Gemma L.
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J.
- Keen Martin
- Kenyon Anita
- Kermack Leanne M.
- Khakh Manjinder
- Kidd Stephen
- Kitchen Christine
- Knapton James
- Knight Bridget A.
- Koshy Cherian
- Kraemer Moritz U. G.
- Kristiansen Mark
- Kuenzi Fred
- Kumziene-SummerhaYes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Lacy Elen De
- Lambson Oliver
- Langford Cordelia F.
- Lawniczak Mara
- Le-Viet Thanh
- Ledesma Juan
- Lee David
- Lee Jack C. D.
- Leek Danielle
- Lehner Paul
- Lensing Stefanie V.
- Leonard Steven
- Leong Clare
- Leslie Ian
- Letchford Laura
- Levene Nick
- Levett Lisa J.
- Lewis Kevin
- Li Kathy K.
- Liddell Kathleen
- Liddle Jennifier
- Liggett Steven
- Lindsey Benjamin B.
- Lister Michelle M.
- Livett Rich
- Lloyd Allyson
- Lo Stephanie
- Loman Nicholas J.
- Loose Matthew W.
- Louka Stavroula F.
- Loveson Katie F.
- Lowe Hannah
- Lowe Helen L.
- Lucaci Anita O.
- Ludden Catherine
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A.
- Macfarlane-Smith Louissa R.
- Machin Nicholas W.
- MacIntyre-Cockett George
- Maclean Alasdair
- Mactavous Lenette
- Madona Pinglawathee
- Maes Mailis
- Mahanama Adhyana I. K.
- Mahungu Tabitha W.
- Mair Daniel
- Maksimovic Joshua
- Makunin Alex
- Malone Cassandra S.
- Manesis Nikos
- Manley Robin
- Manso Carmen
- Marchbank Angela
- Marchetti Filippo
- Margolis Ben
- Martincorena Inigo
- Masoli Jane A. H.
- Mason Jenifer
- Mather Alison E.
- Matheson Nicholas
- Matheson Nicholas J.
- Mathieson Nick
- Matthews Steve
- Maxwell Patrick
- Maxwell Patrick H.
- Mayhew Megan
- Mbisa Tamyo
- McCann Clare
- McCarthy Shane
- McCluggage Kathryn
- McClure Patrick C.
- McFarlane Duncan
- McGuigan Samantha
- McHugh Martin P.
- McKenna James P.
- McKerr Caoimhe
- McManus Georgina M.
- McMurray Claire
- McNally Alan
- McNulty Claire
- Meader Emma J.
- Meadows Lizzie
- Megram Oliver
- Menegazzo Mirko
- Merrick Ian
- Merrill Tammy V.
- Metaxaki Marina
- Miah Shahjahan
- Michell Stephen L.
- Michelsen Michelle L.
- Mills John
- Mirza Jeremy
- Moles-Garcia Emma
- Moll Robin J.
- Mollett Guy
- Molnar Zoltan
- Monaghan Lynn
- Mookerjee Siddharth
- Moore Catherine
- Moore Christopher
- Moore Jonathan
- Moore Nathan
- Morgan Mari
- Morgan Sally
- Morgan Sian
- Mori Matilde
- Moses Samuel
- Mozdzen Barbara
- Muir Peter
- Mungovan Diane
- Munn Robert
- Murphy Edna
- Myers Richard
- Nascimento Fabricia F.
- Nebbia Gaia
- Neely Andy
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nicholls Sam
- Nichols Jenna
- Nickbakhsh Seema
- Niebel Marc O.
- Nikitina Katya
- Nomikou Kyriaki
- Nsonwu Olisaeloka
- Nunez Rocio T. Martinez
- Oliver Karen
- Orton Alexandra
- Orton Richard J.
- Osman Husam
- Ott Sascha
- OâBrien Sarah
- OâGrady Justin
- OâToole Elaine
- OâToole Ăine
- Pacchiarini Nicole
- Packer Simon
- Padgett Debra
- Page Andrew J.
- Palmer Sophie
- Palmer Steve
- Pandey Sarojini
- Park Naomi R.
- Parker Matthew D.
- Parlikad Ajith
- Parmar Surendra
- Parsons Paul J.
- Partridge David G.
- Patel Amita
- Patel Minal
- Patel Vineet
- Paterson Steve
- Paul Hannah
- Payne Brendan AI.
- Peacock Sharon J.
- Peacock Sharon J.
- Pearson Clare
- Percival Benita
- Perry Malorie
- Peto Timothy
- Pinckert Malte
- Pinckert Malte L.
- Platt Steven
- Plimmer Amy
- Poplawski Radoslaw
- Poppitt Steve
- Prestwood Liam
- Price Anna
- Price James
- Prieto Jacqui A.
- Puethe Christoph
- Pusok Monika
- Pybus Oliver G.
- Pymont Hannah M.
- Quail Michael A.
- Quick Joshua
- Quinnell Natalie
- Radecki Asako
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajan Diana
- Rajatileka Shavanthi
- Rambaut Andrew
- Ramsay Mary
- Randell Paul A.
- Rankin Jennifer
- Ratcliffe Liz
- Raub Gabor
- Raviprakash Veena
- Raza Mohammad
- Redshaw Nicholas M.
- Rees Steve
- Rey Sara
- Reynolds Nicola
- Richter Alex
- Ridgman Tom
- Robertson David L.
- Robinson Esther
- Robinson Trevor I.
- Robson Samuel C.
- Rooke Stefan
- Rowan Aileen
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Rushton Steven
- Russell Matthew
- Saeed Kordo
- Saluja Tranprit
- Samaraweera Buddhini
- Sambles Christine M.
- Samtani Vijay
- Samworth Richard
- Sang Fei
- Sato Aris
- Scarlett Garry P.
- Schaefer Ulf
- Scott Carol
- Scott Garren
- Searle Paul
- Shaaban Sharif
- Shah Divya
- Shah Rajiv N.
- Shankar Giri
- Shaw Ashley
- Sheldrake Zara
- Shepherd James G.
- Sheridan Linda
- Sheriff Nicola
- Shirley Lesley
- Signell Adrian W.
- Sillitoe John
- Silveira Siona
- Simpson David A.
- Sing Robert
- Singer Joshua B.
- Sivaprakasam Venkat
- Siveroni Igor
- Sloan Tim J.
- Sluga Graciela
- Smith Colin P.
- Smith Darren
- Smith Kim S.
- Smith Louise
- Smith Nikki
- Smith Wendy
- Smollett Katherine L.
- Snell Luke B.
- Southgate Joel
- Spellman Karla
- Sridhar Sushmita
- Stanley Rachael
- Stanton Thomas D.
- Starinskij Igor
- Stark Richard
- Stockton Joanne
- Stonehouse Susanne
- Storey Nathaniel
- Studholme David J.
- Swindells Emma
- Symmonds Amanda
- Taha Yusri
- Tang Julian
- Taylor Ben E. W.
- Taylor Graham P.
- Taylor Peter
- Taylor Sarah
- Taylor-Joyce Grace
- Temperton Ben
- Templeton Kate E.
- The Cambridge Covid-19 testing Centre
- The COVID-19 Genomics UK (COG-UK) Consortium
- Thompson Thomas
- Thomson Emma C.
- Thornton Alicia
- Thurston Scott A. J.
- Todd John A.
- Tolhurst Jonathan
- Tong Lily
- Tonkin-Hill Gerry
- Torok M. Estee
- Tovar-Corona Jaime M.
- Trebes Amy
- Trotter Alexander J.
- Tsoleridis Theocharis
- Tucker Rachel M.
- Turtle Lance
- Twohig Katherine A.
- Tynan Jo
- Underwood Anthony P.
- University of Cambridge Asymptomatic COVID-19 Screening Programm
- Unnikrishnan Meera
- Valletta Sally
- Vamos Edith E.
- Vasylyeva Tetyana I.
- Vattipally Sreenu
- Vernet Gabrielle
- Vignoles Anna
- Vinnell Martin
- Vipond Ian B.
- Volz Erik M.
- Waddell Ian
- Walsh Sarah
- Wang Dennis
- Wantoch Michelle
- Warne Ben
- Warwick-Dugdale Joanna
- Wastenge Elizabeth
- Watkins Emmeline
- Watkins Joanne
- Watts Joanne
- Waugh Sheila
- Weale Gillian
- Webster Hermione J.
- Weekes Michael P.
- Weldon Danni
- Westhorpe Adam P.
- White Phil
- Whitehead Mark
- Whiteley Max
- Whitwham Andrew
- Wierzbicki Claudia
- Williams Charlotte A.
- Williams Chris
- Williams David
- Williams Lesley-Anne
- Williams Rachel J.
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A.
- Williman Jack
- Willingham Iona
- Wills Mark
- Wilson Harry D.
- Wilson Karl
- Wilson Rebekah E.
- Wilson-Davies Eleri
- Winster Jennifer
- Wise Emma
- Witele Eric
- Workman Chris
- Workman Trudy
- Wright Elizabeth
- Wright Elizabeth
- Wright Giles
- Wright Jo
- Wright Victoria
- Wyatt Tim
- Wyles Matthew
- Wyllie Sarah
- Xu-McCrae Li
- Yeats Corin A.
- Yew Wen Chyin
- Young Greg
- Young Jamie
- Zamudio Marina Escalera
- Zarebski Alex E.
- Zhang Peijun
- Publication venue
- Nature Communications
- Publication date
- 08/02/2022
- Field of study
AbstractUnderstanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020. We perform a detailed phylogenetic comparison with 972 isolates from the surrounding community, complemented with epidemiological and contact tracing data, to determine transmission dynamics. We observe limited viral introductions into the university; the majority of student cases were linked to a single genetic cluster, likely following social gatherings at a venue outside the university. We identify considerable onward transmission associated with student accommodation and courses; this was effectively contained using local infection control measures and following a national lockdown. Transmission clusters were largely segregated within the university or the community. Our study highlights key determinants of SARS-CoV-2 transmission and effective interventions in a higher education setting that will inform public health policy during pandemics.</jats:p
PANC Study (Pancreatitis: A National Cohort Study): national cohort study examining the first 30 days from presentation of acute pancreatitis in the UK
- Author
- Aal Yasser Abdul
- Abbadessa Francesco
- Adesuyi Abidemi
- Adiamah Alfie
- Afza Asma
- Ahmad Jawad
- Ahmad Mustafa Nabeel
- Ahmed Shehzad
- Ain Quratul
- Al-Azzawi Marwa
- Al-Hamed Layal
- Al-Hijaji Mohammed
- Al-Rashedy Mohammed
- Alamassi Amro
- Albalkiny Sherif
- Alfred Joshua
- Ali Sakhawat
- Ali Uzair
- Amir Farhat
- Anele Chukwuemeka
- Angamuthu Natarajan
- Anyomih Theophilus
- Apollos Jeyakumar
- Arambepola Devika
- Argyropoulos Susannah
- Aroori Somaiah
- Arumugam Danaradja
- Arumugam Sathyaseelan
- Assaf Nazrin
- Athwal Tejinderjit
- Awan Altaf
- Azam Saima
- Babalola Olaitan
- Baker Annalie
- Bandyopadhyay Samik
- Banerjee Amlan
- Bardoli Antonio
- Barman Sowrav
- Baron Ryan
- Bashiti Hazem
- Basra Nersheranjeet
- Beatson Kevin
- Bee Charlotte
- Behmida Rami
- Belgaumkar Ajay
- Bell Richard
- Beniwal Abhijeet
- Benjafield Anastasia
- Bennett John
- Berry David
- Bevan Katharine
- Beynon Victoria
- Bhandari Mayank
- Bharucha Shameena
- Bhat Srushti
- Bhatti Sumbal
- Blacklock Callum
- Bleything Zoe
- Bodla Ahmed Salman
- Body Samantha
- Bond Amanda
- Bond-Smith Giles
- Bonomaully Matthew
- Borakati Aditya
- Borg Cynthia-Michelle
- Bota Emil
- Bourne Hannah
- Boven Carine
- Bradley Alison
- Brignall Rhiannon
- Brindle Rachel
- Britton Emily
- Brooks Adam
- Brown Ashley
- Brown Keiran
- Buhain Robert
- Buksh Mahfooz
- Burridge Isobel
- Byrom Richard
- Caldwll Jade
- Cambridge William
- Carr Jenna
- Chakravartty Saurav
- Chan Juen Hao
- Chase Thomas JG
- Chhabra Raunaq
- Chidumije Nnaemeka
- Chin Carven
- Choa George
- Choh Clarisa Thian Puay
- Chohda Ezzat
- Chowdhury Shihab
- Clark James
- Clark Robert
- Claxton Mary
- Clayton Bethan
- Clifford Rachael
- Coe Peter O
- Coles Jennifer
- Collins Alma
- Collins Chris
- Conroy Soraya
- Convie Liam
- Cotton Arthur
- Courtney Michael
- Cowie Stuart
- Craig Eoin
- Cromwell Paul
- Currow Chelise
- Dai Nick
- Damaskos Dimitrios
- Davidson Brian R
- Davis George N
- De Prendergast Alexandra
- Delaney Christopher
- Dhannoon Amenah
- Di Franco Filippo
- Di Mauro Davide
- Difford Tabitha
- DiMaggio Francesco
- Doshi Neel
- Dosis Alexios
- Duncan James
- Dunne Declan
- Dyer Sarah
- Ebied Husam
- Ebraheem Mohamed
- Edwards Katie
- El-Abbassy Islam
- Elkalbash Rema
- Elnaghi Mohamed
- Elnogoomi Ahmed
- Elserafy Amr
- Etherson Kevin
- Eves Peter
- Fagan Leah
- Fallis Simon
- Farrow Emily
- Farrugia Alexia
- Faulkner Gemma
- Ferguson Chanoka
- Finch Guy
- Findlay Alasdair
- Findlay John
- Fisher Simon
- Foster Kate
- Fox Katherine
- Frampton Adam
- Fraser Tessa
- Freeman Rebecca
- Froghi Farid
- Gaber Mohannad
- Gadhvi Adam
- Gala Tanzeela
- Galanopoulos Georgios
- Galea Mark
- Gallagher Tom K
- Gammeri Emanuele
- Gemmill Elizabeth
- Gerogiannis Ioannis
- Ghaneh Paula
- Gilmore Catherine
- Girard Louis-Pierre
- Gismondi Martha
- Golpe Antonio Leyte
- Gray Joanna
- Grey Grace
- Griffith David
- Gulnaz Nadia
- Gunia Dariusz
- Gupta Aayush
- Gupta Ajay
- Gurung Ganga
- Hakeem Abdul
- Halloran Christopher
- Hamid Hytham KS
- Hanbali Nabih
- Handa Siddhartha
- Haq Ehsan Ul
- Harris Chad
- Harrison William
- Hart Patrick
- Hassan Asma
- Hassasing Sapna
- Hawkins William
- Healey Albert
- Heaphy Deborah
- Heer Priya
- Heugh Claire
- Hollyman Marianne
- Hou David
- Hudson Victoria E
- Huppler Lucy
- Husain Najam
- Ibrahim Basil
- Ireland Philip
- Isand Karl
- Islam Muhammad Ariful
- Itobi Emmanuel
- Jackman Jamaall
- Jalil Omar Abdel
- Jamieson Elias
- Janardhanan Pradeep
- Javanmard-Emamghissi Hannah
- Jayawardena Panduka
- Jenkins Bethan
- Johnstone Callum
- Jones Andrew
- Jones Michael
- Jones Rebecca M
- Jones Simon
- Kadambot Safwan Shafeeque
- Kaistha Sumesh
- Kanakala Venkatesh
- Kansal Nisheeth
- Karagiannidis Georgios
- Katbeh Tarek
- Kaul Anil
- Kenington Cleo
- Kennedy-Dalby Andrew
- Kerans George
- Khaddar Ziad Al
- Khalid Ayesha
- Khalil Amjad
- Khalil Hany
- Khan Amnah
- Khan Hamad
- Khanna Chaitra
- Khor Bo Yuan
- Kim Hyun
- Kirmani Naveed
- Knight Stephen R
- Ko Kar Yeung Kenneth
- Koh Amanda
- Kong Keh
- Korwar Vijay
- Kosti Angeliki
- Kourdouli Amar
- Krzak Ada Maria
- Kumar Anil
- Kumar Bhaskar
- Kumar Nagappan
- Kumar Rahul Mohan
- Kuzman Matta
- Kyriakides Charis
- Lahiri Rajiv
- Laing Richard W
- Lango Artemisia
- Larsen Katy
- Latif Javed
- Lavery Lauren
- Lawther Roger
- Lee Rachel Xue Ning
- Lees Bryony
- Lenzi Elisa
- Leswas Dhya Al
- Levy Raphael
- Lim Jie
- Lim Rachel Qian Hui
- Lloyd Emily
- Lo Tammy
- Lo Terence
- Longbotham David
- Luhmann Andreas
- Lund Jonathan N
- Lunevicius Raimundas
- Mack Eleanor
- Magro Tania
- Mahgoub Ahmed
- Majid Shaukat
- Malam Yogeshkumar
- Maliyil Jed
- Manby Paul
- Mann Kulbir
- Manzelli Antonio
- Marriott Paul
- Marsh Luke
- Martin Allie
- Martin Julia
- Mashar Ruchir
- Massella Virginia
- Mathew Malayil
- May-Miller Peter
- McCabe Gerard
- McCallion Stephen
- McCrorie Alan
- McGarry Jennifer
- Meilak Joseph
- Menezes Neville
- Menon Ashok
- Merali Nabeel
- Michel Martin
- Milburn James
- Minicozzi Annamaria
- Mistry Pritesh
- Mitra Smrthi
- Mitton David
- Mohamed Mohamed Saleem Noor
- Mohamed Samy
- Mohammadi-Zaniani Ghazaleh
- Mole Damian
- Moran Emily
- Morrison-Jones Victoria
- Moug Susan J
- Muhammad Fahad Ullah
- Mukherjee Rajarshi
- Murali Navanith
- Murphy Ben
- Murray Hannah
- Mustafa Abdalla
- Muthukumarasamy Girivasan
- Nair Ashitha
- Naqvi Ahmed
- Naqvi Mushal
- Nawaz Ghulam
- Nayar Manu
- Nazir Shahani
- Needham Paul
- Neophytou Christodoulos
- Newman Matthew
- Newton Lydia
- Ng Hwei Jene
- Ng Sherwin
- Ng Vivian
- Nip Lawrence
- Nizami Kulsoom
- Nunes Quentin
- O'Connor Olivia
- Oh Ke En
- Oliphant Raymond
- Olivier James
- Ong Seok Ling
- Ooi Setthasorn Zhi Yang
- Osilli Dixon
- Owen Amy
- Oyende Olamide
- Oyewole Bankole
- OâKelly James
- Pandanaboyana Sanjay
- Parekh Vishal
- Parmar Chetan
- Patel Ameet G
- Patel Ishaan
- Patel Kamlesh
- Patel Panna
- Patel Puja
- Patel Rikhilroy
- Patel Roshni
- Patil Pradeep
- Patnam Varun
- Pawlik Olga
- Pearman Douglas
- Peleki Katerina
- Pervez Ahmed
- Phillips Simon
- Piramanayagam Balasubramanian
- Popa Mariuca
- Porter Darren
- Pournaras Dimitri J
- Powezka Katarzyna
- Prabhu Aishwarya
- Prasanth Manju Nadh
- Presa Roberto
- Puri Aiysha
- Qayum Mohammed Kaif
- Quddus Abdul
- Rahman Rafid
- Rai Jason
- Rajamanickam Shenbaga Kumar
- Rajebhosale Ramprasad
- Rajendran Ilayaraja
- Rajput Kunal
- Ransome Marina
- Rao Milind
- Rao Pawan Kumar Dhruva
- Rao Sudhi
- Rarity Michael
- Rashid Muhammad Umair
- Ravi Prabhu
- Razi Kasra
- Regan Azel
- Richardson Tom
- Rink James
- Roberts Keith J
- Roslan Farah
- Rottenburg Hannah
- Royle James
- Rozwadowski Sophie
- Rybinski Blazej
- Ryska Ondrej
- Saafan Tamer
- Saeed Samerah
- Saha Arin
- Sahl Abdullah Bin
- Saint-Grant Alexander Les
- Saleh Dina
- Salinas Camila Hidalgo
- Sallam Ali
- Sallam Mahmoud
- Sarathy Kasturi
- Sarmah Panchali
- Sawdon Lauren
- Schuijtvlot Nicolaas
- Seeralakandapalan Sarangan
- Sellahewa Sujeewa
- Seretny Luke
- Seta Pooja
- Seymour Keith
- Shah Nehal Sureshkumar
- Shajpal Arjun
- Shamali Awad
- Shanti Hiba
- Sharp Catherine
- Shikh-Bahaei Tamanna
- Shirazi Shahram
- Sivakumar Aran
- Small Sarah
- Smart Chris J
- Smith Andrew M
- Spearman John
- Spellar Kayleigh
- Spiers Harry VM
- Spurring Eleanor
- Strachan David
- Sutton Robert
- Szatmary Peter
- Taha Ahmed
- Talbot Adam
- Tan Yan Yu
- Tanaka Ermal
- Tandon Ashutosh
- Tasleem Sadia
- Tawfik Ahmed
- Taylor Mark
- Telfah Muwaffaq
- Tezas Stergios
- Thanki Sonam
- Thomas Joel
- Tierney Gillian M
- Toh Wei
- Toh Wei Hann
- Toumi Zaher
- Tucker Sophie
- Van Boxel Gijs
- van Laarhoven Stijn
- Varma Aarti
- Vaz Osborne
- Virupaksha Suvi
- Wadley Martin
- Wajed Saj
- Walker Cerys
- Walker Thomas
- Ward Thomas
- Watton Leo
- Wei Rui
- Welsh Joshua
- White Annabelle
- Whitelaw Douglas
- Wiggins Tom
- Wijeyaratne Manuk
- Williams Olatoyosi
- Willis Kevin
- Wilson Iain
- Wilson Michael
- Wolstenholme Caroline
- Wong Alicia
- Wong Grace
- Worku Dawit
- Wright Hannah
- Wyatt Craig
- Yahia Shuker
- Yassin Nuha
- Yeung Denise
- Young John
- Youssef Fahed
- Zafar Muneeb
- Zafar Shahbaz
- Zakeri Roxanna
- Zourob Mohammed
- Zuccarrelli Andrea
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 10/05/2023
- Field of study
Abstract
Background
Acute pancreatitis is a common, yet complex, emergency surgical presentation. Multiple guidelines exist and management can vary significantly. The aim of this first UK, multicentre, prospective cohort study was to assess the variation in management of acute pancreatitis to guide resource planning and optimize treatment.
Methods
All patients aged greater than or equal to 18 years presenting with acute pancreatitis, as per the Atlanta criteria, from March to April 2021 were eligible for inclusion and followed up for 30 days. Anonymized data were uploaded to a secure electronic database in line with local governance approvals.
Results
A total of 113 hospitals contributed data on 2580 patients, with an equal sex distribution and a mean age of 57 years. The aetiology was gallstones in 50.6 per cent, with idiopathic the next most common (22.4 per cent). In addition to the 7.6 per cent with a diagnosis of chronic pancreatitis, 20.1 per cent of patients had a previous episode of acute pancreatitis. One in 20 patients were classed as having severe pancreatitis, as per the Atlanta criteria. The overall mortality rate was 2.3 per cent at 30 days, but rose to one in three in the severe group. Predictors of death included male sex, increased age, and frailty; previous acute pancreatitis and gallstones as aetiologies were protective. Smoking status and body mass index did not affect death.
Conclusion
Most patients presenting with acute pancreatitis have a mild, self-limiting disease. Rates of patients with idiopathic pancreatitis are high. Recurrent attacks of pancreatitis are common, but are likely to have reduced risk of death on subsequent admissions.
</jats:sec
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
- Author
- Aban Marites
- Abayomi Fatola
- Abeyskera Kushala
- Aboagye Jeremy
- Adam Matthew
- Adams Kirsty
- Adamson James
- Adelaja Yemi A.
- Adlou Syed
- Ahmed Khatija
- Akhalwaya Saajida
- Akhalwaya Yasmeen
- Alcock Andrew
- Aley Parvinder K.
- Ali Aabidah
- Allen Elizabeth R.
- Allen Lauren
- Almeida Thamires C. D. S. C
- Alves Mariana P.S.
- Amorim Fabio
- Andritsou Foteini
- Angus Brian
- Anslow Rachel
- Appleby Matthew
- Arbe-Barnes Edward H.
- Ariaans Mark P.
- Arns Beatriz
- Arruda Laiana
- Awedetan Gbadebo
- Azi Lorena
- Azi Paula
- Babbage Gavin
- Bailey Catherine
- Baillie Vicky L.
- Baker Kenneth F.
- Baker Megan
- Baker Natalie
- Baker Philip
- Baldwin Lisa
- Baleanu Ioana
- Bandeira Danieli
- Bara Anna
- Barbosa Marcella A.S.
- Barker Debbie
- Barlow Gavin D.
- Barnabas Shaun L.
- Barnes Eleanor
- Barr Andrew S.
- Barrett Jessica
- Barrett Jordan R.
- Bates Louise
- Batten Alexander
- Beadon Kirsten
- Beales Emily
- Beckley Rebecca
- Belij-Rammerstorfer Sandra
- Bell Jonathan
- Bellamy Duncan
- Bellei Nancy
- Belton Sue
- Berg Adam
- Bermejo Laura
- Berrie Eleanor
- Berry Lisa
- Berzenyi Daniella
- Beveridge Amy
- Bewley Kevin R.
- Bexhell Helen
- Bhikha Sutika
- Bhorat Asad E.
- Bhorat Qasim E.
- Bhorat Zaheda E.
- Bibi Sagida
- Bijker Else
- Birch Geeta
- Birch Sarah
- Bird Adam
- Bird Olivia
- Bisnauthsing Karen
- Bittaye Mustapha
- Blackstone Katherine
- Blackwell Luke
- Bletchly Heather
- Blundell Caitlin L.
- Blundell Susannah R.
- Bodalia Pritesh
- Boettger Bruno C.
- Bolam Emma
- Boland Elena
- Bormans Daan
- Borthwick Nicola
- Bowring Francesca
- Boyd Amy
- Bradley Penny
- Brenner Tanja
- Briner Carmen
- Brown Claire
- Brown Phillip
- Brown-O'Sullivan Charlie
- Bruce Scott
- Brunt Emily
- Buchan Ruaridh
- Budd William
- Bulbulia Yusuf A.
- Bull Melanie
- Burbage Jamie
- Burhan Hassan
- Burn Aileen
- Buttigieg Karen R.
- Byard Nicholas
- Cabera Puig Ingrid
- Calderon Gloria
- Calvert Anna
- Camara Susana
- Cao Michelangelo
- Cappuccini Federica
- Cardoso JoĂŁo R.
- Carr Melanie
- Carroll Miles W.
- Carson-Stevens Andrew
- Carvalho José A.M.
- Carvalho Yasmin de M.
- Casey Helen R.
- Cashen Paul
- Castro Lucia Carratala
- Castro Thais
- Cathie Katrina
- Cavey Ana
- Cerbino-Neto José
- Chadwick Jim
- Chapman David
- Charlton Sue
- Chelysheva Irina
- Chester Oliver
- Chita Sunder
- Cho Jee-Sun
- Cicconi Paola
- Cifuentes Liliana
- Clark Elizabeth
- Clark Matthew
- Clarke Andrea
- Clemens Sue Ann Costa
- Clutterbuck Elizabeth A.
- Colin-Jones Rachel
- Collins Andrea M.
- Collins Sarah L.K.
- Conlon Christopher P.
- Connarty Sean
- Coombes Naomi
- Cooper Cushla
- Cooper Rachel
- Cornelissen Lynne
- Corrah Tumena
- Cosgrove Catherine
- Cox Tony
- Crocker Wendy E.M.
- Crosbie Sarah
- Cullen Dan
- Cullen Lorraine
- Cunha Debora R.M.F.
- Cunningham Christina
- Cuthbertson Fiona C.
- Cutland Clare L.
- Da Guarda Suzete N. Farias
- da Silva Moraes Antonio Carlos
- da Silva Larissa P.
- Damratoski Brad E.
- Danos Zsofia
- Dantas Maria T.D.C.
- Darroch Paula
- Darton Thomas C.
- Datoo Mehreen S.
- Datta Chandrabali
- Davids Malika
- Davies Hannah
- Davies Sarah L.
- Davis Elizabeth
- Davis John
- Davis Judith
- De Jager Jeanne
- De Nobrega Maristela M.D.
- De Oliveira Kalid Lis Moreno
- Dearlove David
- Demissie Tesfaye
- Desai Amisha
- Dheda Keertan
- Di Marco Stefania
- Di Maso Claudio
- Dinelli Maria I.S.
- Dinesh Tanya
- Docksey Claire
- Dold Christina
- Dong Tao
- Donnellan Francesca R.
- Dos Santos Erika Pachecho
- Dos Santos Tannyth
- dos Santos ThainĂĄ G.
- Douglas Alexander D.
- Douglas Naomi
- Downing Charlotte
- Drake Jonathan
- Drake-Brockman Rachael
- Driver Kimberley
- Drury Ruth
- Du Plessis Joan
- Dunachie Susanna J.
- Duncan Christopher J. A.
- Durham Benjamin S.
- Dutra Lidiana
- Easom Nicholas J.W.
- Edwards Mandy
- Edwards Nick J.
- El Muhanna Omar M.
- Elias Sean C.
- Elmore Mike
- Emary Katherine R. W.
- English Marcus
- Esmail Alisgair
- Essack Yakub Moosa
- Ewer Katie J.
- Fairlie Lee
- Farmer Eoghan
- Farooq Mutjaba
- Farrar Madi
- Farrugia Leonard
- Faulkner Beverley
- Faust Saul N.
- Fedosyuk Sofiya
- Felle Sally
- Feng Shuo
- Feng Shuo
- Ferreira Da Silva Carla
- Ferreira Daniela M.
- Field Samantha
- Finn Adam
- Fisher Richard
- Flaxman Amy
- Fletcher James
- Fofie Hazel
- Fok Henry
- Folegatti Pedro M.
- Ford Karen J.
- Fowler Jamie
- Fraiman Pedro H.A.
- Francis Emma
- Franco Marilia M.
- Frater John
- Freire MarilĂșcia S.M.
- Fry Samantha H.
- Fudge Sabrina
- Furze Julie
- Fuskova Michelle
- Galian-Rubio Pablo
- Galiza Eva
- Garlant Harriet
- Gavrila Madita
- Geddes Ailsa
- Gibbons Karyna A.
- Gilbert Sarah C
- Gilbride Ciaran
- Gill Hardeep
- Glynn Sharon
- Godwin Kerry
- Gokani Karishma
- Goldoni Ursula Carvalho
- Goncalves Maria
- Gonzalez Isabela G.S.
- Goodman Anna L.
- Goodwin Jayne
- Goondiwala Amina
- Gordon-Quayle Katherine
- Gorini Giacomo
- Grab Janet
- Gracie Lara
- Green Catherine M.
- Green Christopher A.
- Greenland Melanie
- Greenwood Nicola
- Greffrath Johann
- Groenewald Marisa M.
- Grossi Leonardo
- Gupta Gaurav
- Hackett Mark
- Hallis Bassam
- Hamaluba Mainga
- Hamilton Elizabeth
- Hammersley Daniel
- Hanrath Aidan T.
- Hanumunthadu Brama
- Harris Clair
- Harris Stephanie A.
- Harris Tara
- Harrison Daisy
- Harrison Thomas D.
- Hart Thomas C.
- Hartnell Birgit
- Hassan Shadin
- Haughney John
- Hawkins Sophia
- Hay Jodie
- Head Ian
- Heath Paul T.
- Henry John
- Hermosin Herrera Macarena
- Hettle David B.
- Hill Adrian V. S.
- Hill Catherine
- Hill Helen
- Hill Jennifer
- Hirsch Ian
- Hodges Gina
- Hodgson Susanne H. C.
- Horne Elizea
- Hou Mimi M.
- Houlihan Catherine
- Howe Elizabeth
- Howell Nicola
- Humphreys Jonathan
- Humphries Holly E.
- Hurley Katrina
- Huson Claire
- Hyamns Catherine
- Hyder-Wright Angela
- Ikram Sabina
- Ishwarbhai Alka
- Ivan Monica
- Iveson Poppy
- Iyer Vidyashankara
- Izu Alane
- Jackson Frederic
- Jackson Susan
- Jaumdally Shameem
- Jeffers Helen
- Jenkin Daniel
- Jesudason Natasha
- Joe Carina C. D.
- Jones Bryony
- Jones Christopher
- Jones Elizabeth
- Jones Kathryn
- Jorge Marianna Rocha
- Jose Aylin
- Joshi Amar
- JĂșnior Eduardo A.M.S.
- Kadziola Joanne
- Kailath Reshma
- Kana Faeeza
- Karampatsas Konstantinos
- Kasanyinga Mwila
- Keen Jade
- Kelly Dearbhla M.
- Kelly Debbie
- Kelly Elizabeth J.
- Kelly Sarah
- Kerr David
- Kerridge Simon
- Kfouri Renato de Ăvila
- Khan Liaquat
- Khozoee Baktash
- Kidd Sarah
- Killen Annabel
- Kinch Jasmin
- Kinch Patrick
- King Lloyd D.W.
- King Thomas B.
- Kingham Lucy
- Klenerman Paul
- Knapper Francesca
- Knight Julian C.
- Knott Daniel
- Koen Anthonet
- Koleva Stanislava
- Kwatra Gaurav
- Lambe Teresa
- Lang Gail
- Lang Matilda
- Larkworthy Colin W.
- Larwood Jessica P.J.
- Law Rebecca
- Lawrie Alison M.
- Lazarus Erica M.
- Lazarus Rajeka
- Leach Amanda
- Lees Emily A.
- Lelliott Alice
- Lemm Nana-Marie
- Lessa Alvaro
- Leung Stephanie
- Li Yuanyuan
- Lias Amelia M.
- Liatsikos Kostas
- Libri Vincenzo
- Lillie Patrick J.
- Linder Aline
- Lipworth Samuel
- Liu Shuchang
- Liu Xinxue
- Lloyd Adam
- Lloyd Stephanie
- Loew Lisa
- Lopez Ramon Raquel
- Lora Leandro
- Lowthorpe Vicki
- Luz Kleber
- MacDonald Jonathan C.
- MacGregor Gordon
- Madhavan Meera
- Madhi Shabir A.
- Mainwaring David O.
- Makambwa Edson
- Makinson Rebecca
- Malahleha Mookho
- Malamatsho Ross
- Mallett Garry
- Mallory Raburn
- Mansatta Kushal
- Maoko Takalani
- Mapetla Katlego
- Marchevsky Natalie G.
- Marinou Spyridoula
- Marlow Emma
- Marques Gabriela N.
- Marriott Paula
- Marshall Julia L.
- Marshall Richard P.
- Martins FlĂĄvia J.
- Masenya Masebole
- Masilela Mduduzi
- Masters Shauna K.
- Mathew Moncy
- Matlebjane Hosea
- Matshidiso Kedidimetse
- Mazur Olga
- Mazzella Andrea
- McCaughan Hugh
- McEwan Joanne
- McGlashan Joanna
- McGregor Alastair
- McInroy Lorna
- McIntyre Zoe
- McLenaghan Daniela
- McRobert Nicky
- McSwiggan Steve
- Megson Clare
- Mehdipour Savviz
- Meijs Wilma
- Mendes Ana V .A.
- Mendonça Renata N.Ă.
- Mentzer Alexander J.
- Milan Eveline P.
- Minassian Angela M.
- Mirtorabi Neginsadat
- Mitton Celia
- Mnyakeni Sibusiso
- Moghaddas Fiona
- Molapo Kgaogelo
- Moloi Mapule
- Moore Maria
- Moraes-Pinto M. Isabel
- Moran Marni
- Morey Ella
- Morgans RĂłisĂn
- Morris Helen C.
- Morris Sheila
- Morris Susan
- Morrison Hazel
- Morselli Franca
- Morshead Gertraud
- Morter Richard
- Mottal Lynelle
- Moultrie Andrew
- Moya Nathifa
- Mpelembue Mushiya
- Msomi Sibekezelo
- Mugodi Yvonne
- Mujadidi Yama F.
- Mukhopadhyay Ekta
- Muller Jilly
- Munro Alasdair
- Munro Claire
- Murphy Sarah
- Mweu Philomena
- Myasaki Celia Hatsuko
- Naik Gurudutt
- Naker Kush
- Nana Anusha
- Nastouli Eleni
- Nazir Abida
- Ndlovu Bongani
- Neffa Fabio
- Njenga Cecilia
- Noal Helena
- Novaes Gabrielle
- Noé Andrés
- Nugent Fay L.
- Nunes GĂ©ssika
- O'Brien Katie
- O'Connor Daniel
- O'Reilly Paula
- O'Reilly Peter J.
- Odam Miranda
- Oelofse Suzette
- Oguti Blanche
- Olchawski Victoria
- Oldfield Neil J.
- Oliveira Catarina
- Oliveira Marianne G.
- Oosthuizen Angela
- Osborne Piper
- Owen David R.J.
- Owen Lydia
- Owens Daniel
- Owino Nelly
- Pacurar Mihaela
- Padayachee Sherman D.
- Paiva Brenda V.B.
- Palhares Edna M.F.
- Palmer Susan
- Parkinson Sivapriyai
- Parracho Helena M.R.T.
- Parsons Karen
- Patel Bhumika
- Patel Dipak
- Patel Faeezah
- Patel Kelly
- Patrick-Smith Maia
- Payne Ruth O.
- Peng Yanchun
- Penn Elizabeth J.
- Pennington Anna
- Peralta Alvarez Marco Polo
- Perring James
- Perry Nicola
- Perumal Rubeshan
- Petkar Sahir
- Philip Tricia
- Phillips Daniel J.
- Phillips Jennifer
- Phohu Mary Kgomotso
- Pickup Lorinda
- Pieterse Sonja
- Piper Jo
- Pipini Dimitra
- Pittella Ana
- Plank Mary
- Plested Emma
- Pollard Andrew J
- Pollard Samuel
- Pollock Katrina M.
- Pooley Jennifer
- Pooran Anil
- Poulton Ian
- Powers Claire
- Presa Fernando B.
- Price David A.
- Price Vivien
- Primeira Marcelo
- Proud Pamela C.
- Provstgaard-Morys Samuel
- Pueschel Sophie
- Pulido David
- Quaid Sheena
- Rabara Ria
- Radford Alexandra
- Radia Kajal
- Rajapaska Durga
- Rajeswaran Thurkka
- Ramasamy Maheshi N.
- Ramos Lopez Fernando
- Ramos Alberto San Francisco
- Rampling Tommy
- Rand Jade
- Ratcliffe Helen
- Rawlinson Tom
- Rea David
- Rees Byron
- ReinĂ© JesĂșs
- Resuello-Dauti Mila
- Reyes Pabon Emilia
- Rhead Sarah
- Ribiero Carla M.
- Ricamara Marivic
- Richter Alex
- Ritchie Adam J.
- Ritchie Neil
- Robbins Alexander J.
- Roberts Hannah
- Robinson Hannah
- Robinson Ryan E.
- Rocchetti Talita T.
- Rocha Beatriz Pinho
- Roche Sophie
- Rollier Christine
- Rose Louisa
- Ross Russell Amy L.
- Rossouw Lindie
- Royal Simon
- Rudiansyah Indra
- Ruiz Sarah
- Saich Stephen
- Sala Claudia
- Sale Jessica
- Salman Ahmed M.
- Salvador Natalia
- Salvador Stephannie
- Sampaio Milla
- Samson Annette D.
- Sanchez-Gonzalez Amada
- Sanders Helen
- Sanders Katherine
- Santos Guerra Mayara F.S.
- Santos Erika
- Satti Iman
- Saunders Caroline
- Saunders Jack E.
- Sayed Aakifah
- Schim van der Loeff Ina
- Schmid Annina B.
- Schofield Ella
- Schwarzbold Alexandre V.
- Screaton Gavin
- Seddiqi Samiullah
- Segireddy Rameswara R.
- Senger Roberta
- Serrano Sonia
- Shah Rajiv
- Shaik Imam
- Sharpe Hannah E.
- Sharrocks Katherine
- Shaw Robert
- Shea Adam
- Shepherd Amy
- Shepherd James G.
- Shiham Farah
- Sidhom Emad
- Silk Sarah E.
- Silva-Junior Gilberto
- Silva-Reyes Laura
- Silveira Anderson D.
- Silveira Mariana B.V.
- Singh Nisha
- Sinha Jaisi
- Skelly Donal T.
- Smith Andrew
- Smith Catherine C.
- Smith Daniel C.
- Smith David J.
- Smith Holly E.
- Smith Nick
- Snape Matthew D.
- Soares Airanuédida
- Soares Tiago
- SolĂłrzano Carla
- Song Rinn
- Sorio Guilherme L.
- Sorley Kim
- Sosa-Rodriguez Tiffany
- Souza Alessandra R.
- Souza Bruno S.D.F.
- Souza Cinthia M.C.D.L.
- Spencer Alexandra J.
- Spina Fernanda
- Spoors Louise
- Sprinz Eduardo
- Stafford Lizzie
- Stamford Imogen
- Starinskij Igor
- Stein Ricardo
- Steven Jill
- Stockdale Lisa
- Stockwell Lisa V.
- Strickland Louise H.
- Stuart Arabella C.
- Sturdy Ann
- Sutherland Rebecca K.
- Sutton Natalina
- Szigeti Anna
- Tahiri-Alaoui Abdessamad
- Tanner Rachel
- Taoushanis Carol
- Tarr Alexander W.
- Tarrant Richard
- Taylor Iona Jennifer
- Taylor Justin
- Taylor Keja
- Taylor Ursula
- te Water Naude Rebecca
- Themistocleous Andreas
- Themistocleous Yrene
- Thomas Kelly
- Thomas Merin
- Thomas Tonia M.
- Thombrayil Asha
- Thompson Amber
- Thompson Ameeka
- Thompson Fawziyah
- Thompson Kevin
- Thomson Emma C.
- Thomson Julia
- Thornton-Jones Viv
- Tighe Patrick J.
- Tinoco Lygia Accioly
- Tiongson Gerlynn
- Tladinyane Bonolo
- Tomasicchio Michele
- Tomic Adriana
- Tonks Susan
- Toshner Mark
- Tran Nguyen
- Tree Julia
- Trillana Gerry
- Trinham Charlotte
- Trivett Rose
- Truby Adam
- Tsheko Betty Lebogang
- Turabi Aadil
- Turner Cheryl
- Turner David P. J.
- Turner Richard
- Török M Estée
- Ulaszewska Marta
- Underwood Benjamin R.
- van Eck Samual
- Varughese Rachel
- Vekemans Johan
- Verbart Dennis
- Verheul Marije
- Vichos Iason
- Vieira Taiane
- Villafana Tonya L.
- Voysey Merryn
- Waddington Claire S.
- Walker Laura
- Wallis Erica
- Wand Matthew
- Warbick Deborah
- Wardell Theresa
- Warimwe George
- Warren Sarah C.
- Watkins Bridget
- Watson Ekaterina
- Watson Marion E. E.
- Webb Stewart
- Webb-Bridges Alice
- Webster Angela
- Weckx Lily Y.
- Welch Jessica
- Wells Jeanette
- West Alison
- White Caroline
- White Rachel
- Williams Christopher J.
- Williams Paul
- Williams Rachel L.
- Winslow Rebecca
- Woodyer Mark
- Worth Andrew T.
- Wright Danny
- Wroblewska Marzena
- Yao Andy
- Zimmer Rafael
- Zizi Dalila
- Zuidewind Peter
- Publication venue
- 'Elsevier BV'
- Publication date
- 03/12/2020
- Field of study
BACKGROUND: A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials. METHODS: This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5âĂâ1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1â-ârelative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674. FINDINGS: Between April 23 and Nov 4, 2020, 23â848 participants were enrolled and 11â636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0-75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4-97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8-80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74â341 person-months of safety follow-up (median 3·4 months, IQR 1·3-4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation. INTERPRETATION: ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials. FUNDING: UK Research and Innovation, National Institutes for Health Research (NIHR), Coalition for Epidemic Preparedness Innovations, Bill & Melinda Gates Foundation, Lemann Foundation, Rede D'Or, Brava and Telles Foundation, NIHR Oxford Biomedical Research Centre, Thames Valley and South Midland's NIHR Clinical Research Network, and AstraZeneca
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
- Author
- Aban Marites
- Abayomi Fatola
- Abeyskera Kushala
- Aboagye Jeremy
- Adam Matthew
- Adams Kirsty
- Adamson James
- Adelaja Yemi A.
- Adlou Syed
- Ahmed Khatija
- Akhalwaya Saajida
- Akhalwaya Yasmeen
- Alcock Andrew
- Aley Parvinder K.
- Ali Aabidah
- Allen Elizabeth R.
- Allen Lauren
- Almeida Thamires C. D. S. C
- Alves Mariana P.S.
- Amorim Fabio
- Andritsou Foteini
- Angus Brian
- Anslow Rachel
- Appleby Matthew
- Arbe-Barnes Edward H.
- Ariaans Mark P.
- Arns Beatriz
- Arruda Laiana
- Awedetan Gbadebo
- Azi Lorena
- Azi Paula
- Babbage Gavin
- Bailey Catherine
- Baillie Vicky L.
- Baker Kenneth F.
- Baker Megan
- Baker Natalie
- Baker Philip
- Baldwin Lisa
- Baleanu Ioana
- Bandeira Danieli
- Bara Anna
- Barbosa Marcella A.S.
- Barker Debbie
- Barlow Gavin D.
- Barnabas Shaun L.
- Barnes Eleanor
- Barr Andrew S.
- Barrett Jessica
- Barrett Jordan R.
- Bates Louise
- Batten Alexander
- Beadon Kirsten
- Beales Emily
- Beckley Rebecca
- Belij-Rammerstorfer Sandra
- Bell Jonathan
- Bellamy Duncan
- Bellei Nancy
- Belton Sue
- Berg Adam
- Bermejo Laura
- Berrie Eleanor
- Berry Lisa
- Berzenyi Daniella
- Beveridge Amy
- Bewley Kevin R.
- Bexhell Helen
- Bhikha Sutika
- Bhorat Asad E.
- Bhorat Qasim E.
- Bhorat Zaheda E.
- Bibi Sagida
- Bijker Else
- Birch Geeta
- Birch Sarah
- Bird Adam
- Bird Olivia
- Bisnauthsing Karen
- Bittaye Mustapha
- Blackstone Katherine
- Blackwell Luke
- Bletchly Heather
- Blundell Caitlin L.
- Blundell Susannah R.
- Bodalia Pritesh
- Boettger Bruno C.
- Bolam Emma
- Boland Elena
- Bormans Daan
- Borthwick Nicola
- Bowring Francesca
- Boyd Amy
- Bradley Penny
- Brenner Tanja
- Briner Carmen
- Brown Claire
- Brown Phillip
- Brown-O'Sullivan Charlie
- Bruce Scott
- Brunt Emily
- Buchan Ruaridh
- Budd William
- Bulbulia Yusuf A.
- Bull Melanie
- Burbage Jamie
- Burhan Hassan
- Burn Aileen
- Buttigieg Karen R.
- Byard Nicholas
- Cabera Puig Ingrid
- Calderon Gloria
- Calvert Anna
- Camara Susana
- Cao Michelangelo
- Cappuccini Federica
- Cardoso JoĂŁo R.
- Carr Melanie
- Carroll Miles W.
- Carson-Stevens Andrew
- Carvalho José A.M.
- Carvalho Yasmin de M.
- Casey Helen R.
- Cashen Paul
- Castro Lucia Carratala
- Castro Thais
- Cathie Katrina
- Cavey Ana
- Cerbino-Neto José
- Chadwick Jim
- Chapman David
- Charlton Sue
- Chelysheva Irina
- Chester Oliver
- Chita Sunder
- Cho Jee-Sun
- Cicconi Paola
- Cifuentes Liliana
- Clark Elizabeth
- Clark Matthew
- Clarke Andrea
- Clemens Sue Ann Costa
- Clutterbuck Elizabeth A.
- Colin-Jones Rachel
- Collins Andrea M.
- Collins Sarah L.K.
- Conlon Christopher P.
- Connarty Sean
- Coombes Naomi
- Cooper Cushla
- Cooper Rachel
- Cornelissen Lynne
- Corrah Tumena
- Cosgrove Catherine
- Cox Tony
- Crocker Wendy E.M.
- Crosbie Sarah
- Cullen Dan
- Cullen Lorraine
- Cunha Debora R.M.F.
- Cunningham Christina
- Cuthbertson Fiona C.
- Cutland Clare L.
- Da Guarda Suzete N. Farias
- da Silva Moraes Antonio Carlos
- da Silva Larissa P.
- Damratoski Brad E.
- Danos Zsofia
- Dantas Maria T.D.C.
- Darroch Paula
- Darton Thomas C.
- Datoo Mehreen S.
- Datta Chandrabali
- Davids Malika
- Davies Hannah
- Davies Sarah L.
- Davis Elizabeth
- Davis John
- Davis Judith
- De Jager Jeanne
- De Nobrega Maristela M.D.
- De Oliveira Kalid Lis Moreno
- Dearlove David
- Demissie Tesfaye
- Desai Amisha
- Dheda Keertan
- Di Marco Stefania
- Di Maso Claudio
- Dinelli Maria I.S.
- Dinesh Tanya
- Docksey Claire
- Dold Christina
- Dong Tao
- Donnellan Francesca R.
- Dos Santos Erika Pachecho
- Dos Santos Tannyth
- dos Santos ThainĂĄ G.
- Douglas Alexander D.
- Douglas Naomi
- Downing Charlotte
- Drake Jonathan
- Drake-Brockman Rachael
- Driver Kimberley
- Drury Ruth
- Du Plessis Joan
- Dunachie Susanna J.
- Duncan Christopher J. A.
- Durham Benjamin S.
- Dutra Lidiana
- Easom Nicholas J.W.
- Edwards Mandy
- Edwards Nick J.
- El Muhanna Omar M.
- Elias Sean C.
- Elmore Mike
- Emary Katherine R. W.
- English Marcus
- Esmail Alisgair
- Essack Yakub Moosa
- Ewer Katie J.
- Fairlie Lee
- Farmer Eoghan
- Farooq Mutjaba
- Farrar Madi
- Farrugia Leonard
- Faulkner Beverley
- Faust Saul N.
- Fedosyuk Sofiya
- Felle Sally
- Feng Shuo
- Feng Shuo
- Ferreira Da Silva Carla
- Ferreira Daniela M.
- Field Samantha
- Finn Adam
- Fisher Richard
- Flaxman Amy
- Fletcher James
- Fofie Hazel
- Fok Henry
- Folegatti Pedro M.
- Ford Karen J.
- Fowler Jamie
- Fraiman Pedro H.A.
- Francis Emma
- Franco Marilia M.
- Frater John
- Freire MarilĂșcia S.M.
- Fry Samantha H.
- Fudge Sabrina
- Furze Julie
- Fuskova Michelle
- Galian-Rubio Pablo
- Galiza Eva
- Garlant Harriet
- Gavrila Madita
- Geddes Ailsa
- Gibbons Karyna A.
- Gilbert Sarah C
- Gilbride Ciaran
- Gill Hardeep
- Glynn Sharon
- Godwin Kerry
- Gokani Karishma
- Goldoni Ursula Carvalho
- Goncalves Maria
- Gonzalez Isabela G.S.
- Goodman Anna L.
- Goodwin Jayne
- Goondiwala Amina
- Gordon-Quayle Katherine
- Gorini Giacomo
- Grab Janet
- Gracie Lara
- Green Catherine M.
- Green Christopher A.
- Greenland Melanie
- Greenwood Nicola
- Greffrath Johann
- Groenewald Marisa M.
- Grossi Leonardo
- Gupta Gaurav
- Hackett Mark
- Hallis Bassam
- Hamaluba Mainga
- Hamilton Elizabeth
- Hammersley Daniel
- Hanrath Aidan T.
- Hanumunthadu Brama
- Harris Clair
- Harris Stephanie A.
- Harris Tara
- Harrison Daisy
- Harrison Thomas D.
- Hart Thomas C.
- Hartnell Birgit
- Hassan Shadin
- Haughney John
- Hawkins Sophia
- Hay Jodie
- Head Ian
- Heath Paul T.
- Henry John
- Hermosin Herrera Macarena
- Hettle David B.
- Hill Adrian V. S.
- Hill Catherine
- Hill Helen
- Hill Jennifer
- Hirsch Ian
- Hodges Gina
- Hodgson Susanne H. C.
- Horne Elizea
- Hou Mimi M.
- Houlihan Catherine
- Howe Elizabeth
- Howell Nicola
- Humphreys Jonathan
- Humphries Holly E.
- Hurley Katrina
- Huson Claire
- Hyamns Catherine
- Hyder-Wright Angela
- Ikram Sabina
- Ishwarbhai Alka
- Ivan Monica
- Iveson Poppy
- Iyer Vidyashankara
- Izu Alane
- Jackson Frederic
- Jackson Susan
- Jaumdally Shameem
- Jeffers Helen
- Jenkin Daniel
- Jesudason Natasha
- Joe Carina C. D.
- Jones Bryony
- Jones Christopher
- Jones Elizabeth
- Jones Kathryn
- Jorge Marianna Rocha
- Jose Aylin
- Joshi Amar
- JĂșnior Eduardo A.M.S.
- Kadziola Joanne
- Kailath Reshma
- Kana Faeeza
- Karampatsas Konstantinos
- Kasanyinga Mwila
- Keen Jade
- Kelly Dearbhla M.
- Kelly Debbie
- Kelly Elizabeth J.
- Kelly Sarah
- Kerr David
- Kerridge Simon
- Kfouri Renato de Ăvila
- Khan Liaquat
- Khozoee Baktash
- Kidd Sarah
- Killen Annabel
- Kinch Jasmin
- Kinch Patrick
- King Lloyd D.W.
- King Thomas B.
- Kingham Lucy
- Klenerman Paul
- Knapper Francesca
- Knight Julian C.
- Knott Daniel
- Koen Anthonet
- Koleva Stanislava
- Kwatra Gaurav
- Lambe Teresa
- Lang Gail
- Lang Matilda
- Larkworthy Colin W.
- Larwood Jessica P.J.
- Law Rebecca
- Lawrie Alison M.
- Lazarus Erica M.
- Lazarus Rajeka
- Leach Amanda
- Lees Emily A.
- Lelliott Alice
- Lemm Nana-Marie
- Lessa Alvaro
- Leung Stephanie
- Li Yuanyuan
- Lias Amelia M.
- Liatsikos Kostas
- Libri Vincenzo
- Lillie Patrick J.
- Linder Aline
- Lipworth Samuel
- Liu Shuchang
- Liu Xinxue
- Lloyd Adam
- Lloyd Stephanie
- Loew Lisa
- Lopez Ramon Raquel
- Lora Leandro
- Lowthorpe Vicki
- Luz Kleber
- MacDonald Jonathan C.
- MacGregor Gordon
- Madhavan Meera
- Madhi Shabir A.
- Mainwaring David O.
- Makambwa Edson
- Makinson Rebecca
- Malahleha Mookho
- Malamatsho Ross
- Mallett Garry
- Mallory Raburn
- Mansatta Kushal
- Maoko Takalani
- Mapetla Katlego
- Marchevsky Natalie G.
- Marinou Spyridoula
- Marlow Emma
- Marques Gabriela N.
- Marriott Paula
- Marshall Julia L.
- Marshall Richard P.
- Martins FlĂĄvia J.
- Masenya Masebole
- Masilela Mduduzi
- Masters Shauna K.
- Mathew Moncy
- Matlebjane Hosea
- Matshidiso Kedidimetse
- Mazur Olga
- Mazzella Andrea
- McCaughan Hugh
- McEwan Joanne
- McGlashan Joanna
- McGregor Alastair
- McInroy Lorna
- McIntyre Zoe
- McLenaghan Daniela
- McRobert Nicky
- McSwiggan Steve
- Megson Clare
- Mehdipour Savviz
- Meijs Wilma
- Mendes Ana V .A.
- Mendonça Renata N.Ă.
- Mentzer Alexander J.
- Milan Eveline P.
- Minassian Angela M.
- Mirtorabi Neginsadat
- Mitton Celia
- Mnyakeni Sibusiso
- Moghaddas Fiona
- Molapo Kgaogelo
- Moloi Mapule
- Moore Maria
- Moraes-Pinto M. Isabel
- Moran Marni
- Morey Ella
- Morgans RĂłisĂn
- Morris Helen C.
- Morris Sheila
- Morris Susan
- Morrison Hazel
- Morselli Franca
- Morshead Gertraud
- Morter Richard
- Mottal Lynelle
- Moultrie Andrew
- Moya Nathifa
- Mpelembue Mushiya
- Msomi Sibekezelo
- Mugodi Yvonne
- Mujadidi Yama F.
- Mukhopadhyay Ekta
- Muller Jilly
- Munro Alasdair
- Munro Claire
- Murphy Sarah
- Mweu Philomena
- Myasaki Celia Hatsuko
- Naik Gurudutt
- Naker Kush
- Nana Anusha
- Nastouli Eleni
- Nazir Abida
- Ndlovu Bongani
- Neffa Fabio
- Njenga Cecilia
- Noal Helena
- Novaes Gabrielle
- Noé Andrés
- Nugent Fay L.
- Nunes GĂ©ssika
- O'Brien Katie
- O'Connor Daniel
- O'Reilly Paula
- O'Reilly Peter J.
- Odam Miranda
- Oelofse Suzette
- Oguti Blanche
- Olchawski Victoria
- Oldfield Neil J.
- Oliveira Catarina
- Oliveira Marianne G.
- Oosthuizen Angela
- Osborne Piper
- Owen David R.J.
- Owen Lydia
- Owens Daniel
- Owino Nelly
- Pacurar Mihaela
- Padayachee Sherman D.
- Paiva Brenda V.B.
- Palhares Edna M.F.
- Palmer Susan
- Parkinson Sivapriyai
- Parracho Helena M.R.T.
- Parsons Karen
- Patel Bhumika
- Patel Dipak
- Patel Faeezah
- Patel Kelly
- Patrick-Smith Maia
- Payne Ruth O.
- Peng Yanchun
- Penn Elizabeth J.
- Pennington Anna
- Peralta Alvarez Marco Polo
- Perring James
- Perry Nicola
- Perumal Rubeshan
- Petkar Sahir
- Philip Tricia
- Phillips Daniel J.
- Phillips Jennifer
- Phohu Mary Kgomotso
- Pickup Lorinda
- Pieterse Sonja
- Piper Jo
- Pipini Dimitra
- Pittella Ana
- Plank Mary
- Plested Emma
- Pollard Andrew J
- Pollard Samuel
- Pollock Katrina M.
- Pooley Jennifer
- Pooran Anil
- Poulton Ian
- Powers Claire
- Presa Fernando B.
- Price David A.
- Price Vivien
- Primeira Marcelo
- Proud Pamela C.
- Provstgaard-Morys Samuel
- Pueschel Sophie
- Pulido David
- Quaid Sheena
- Rabara Ria
- Radford Alexandra
- Radia Kajal
- Rajapaska Durga
- Rajeswaran Thurkka
- Ramasamy Maheshi N.
- Ramos Lopez Fernando
- Ramos Alberto San Francisco
- Rampling Tommy
- Rand Jade
- Ratcliffe Helen
- Rawlinson Tom
- Rea David
- Rees Byron
- ReinĂ© JesĂșs
- Resuello-Dauti Mila
- Reyes Pabon Emilia
- Rhead Sarah
- Ribiero Carla M.
- Ricamara Marivic
- Richter Alex
- Ritchie Adam J.
- Ritchie Neil
- Robbins Alexander J.
- Roberts Hannah
- Robinson Hannah
- Robinson Ryan E.
- Rocchetti Talita T.
- Rocha Beatriz Pinho
- Roche Sophie
- Rollier Christine
- Rose Louisa
- Ross Russell Amy L.
- Rossouw Lindie
- Royal Simon
- Rudiansyah Indra
- Ruiz Sarah
- Saich Stephen
- Sala Claudia
- Sale Jessica
- Salman Ahmed M.
- Salvador Natalia
- Salvador Stephannie
- Sampaio Milla
- Samson Annette D.
- Sanchez-Gonzalez Amada
- Sanders Helen
- Sanders Katherine
- Santos Guerra Mayara F.S.
- Santos Erika
- Satti Iman
- Saunders Caroline
- Saunders Jack E.
- Sayed Aakifah
- Schim van der Loeff Ina
- Schmid Annina B.
- Schofield Ella
- Schwarzbold Alexandre V.
- Screaton Gavin
- Seddiqi Samiullah
- Segireddy Rameswara R.
- Senger Roberta
- Serrano Sonia
- Shah Rajiv
- Shaik Imam
- Sharpe Hannah E.
- Sharrocks Katherine
- Shaw Robert
- Shea Adam
- Shepherd Amy
- Shepherd James G.
- Shiham Farah
- Sidhom Emad
- Silk Sarah E.
- Silva-Junior Gilberto
- Silva-Reyes Laura
- Silveira Anderson D.
- Silveira Mariana B.V.
- Singh Nisha
- Sinha Jaisi
- Skelly Donal T.
- Smith Andrew
- Smith Catherine C.
- Smith Daniel C.
- Smith David J.
- Smith Holly E.
- Smith Nick
- Snape Matthew D.
- Soares Airanuédida
- Soares Tiago
- SolĂłrzano Carla
- Song Rinn
- Sorio Guilherme L.
- Sorley Kim
- Sosa-Rodriguez Tiffany
- Souza Alessandra R.
- Souza Bruno S.D.F.
- Souza Cinthia M.C.D.L.
- Spencer Alexandra J.
- Spina Fernanda
- Spoors Louise
- Sprinz Eduardo
- Stafford Lizzie
- Stamford Imogen
- Starinskij Igor
- Stein Ricardo
- Steven Jill
- Stockdale Lisa
- Stockwell Lisa V.
- Strickland Louise H.
- Stuart Arabella C.
- Sturdy Ann
- Sutherland Rebecca K.
- Sutton Natalina
- Szigeti Anna
- Tahiri-Alaoui Abdessamad
- Tanner Rachel
- Taoushanis Carol
- Tarr Alexander W.
- Tarrant Richard
- Taylor Iona Jennifer
- Taylor Justin
- Taylor Keja
- Taylor Ursula
- te Water Naude Rebecca
- Themistocleous Andreas
- Themistocleous Yrene
- Thomas Kelly
- Thomas Merin
- Thomas Tonia M.
- Thombrayil Asha
- Thompson Amber
- Thompson Ameeka
- Thompson Fawziyah
- Thompson Kevin
- Thomson Emma C.
- Thomson Julia
- Thornton-Jones Viv
- Tighe Patrick J.
- Tinoco Lygia Accioly
- Tiongson Gerlynn
- Tladinyane Bonolo
- Tomasicchio Michele
- Tomic Adriana
- Tonks Susan
- Toshner Mark
- Tran Nguyen
- Tree Julia
- Trillana Gerry
- Trinham Charlotte
- Trivett Rose
- Truby Adam
- Tsheko Betty Lebogang
- Turabi Aadil
- Turner Cheryl
- Turner David P. J.
- Turner Richard
- Török M Estée
- Ulaszewska Marta
- Underwood Benjamin R.
- van Eck Samual
- Varughese Rachel
- Vekemans Johan
- Verbart Dennis
- Verheul Marije
- Vichos Iason
- Vieira Taiane
- Villafana Tonya L.
- Voysey Merryn
- Waddington Claire S.
- Walker Laura
- Wallis Erica
- Wand Matthew
- Warbick Deborah
- Wardell Theresa
- Warimwe George
- Warren Sarah C.
- Watkins Bridget
- Watson Ekaterina
- Watson Marion E. E.
- Webb Stewart
- Webb-Bridges Alice
- Webster Angela
- Weckx Lily Y.
- Welch Jessica
- Wells Jeanette
- West Alison
- White Caroline
- White Rachel
- Williams Christopher J.
- Williams Paul
- Williams Rachel L.
- Winslow Rebecca
- Woodyer Mark
- Worth Andrew T.
- Wright Danny
- Wroblewska Marzena
- Yao Andy
- Zimmer Rafael
- Zizi Dalila
- Zuidewind Peter
- Publication venue
- 'Elsevier BV'
- Publication date
- 09/01/2021
- Field of study
Background
A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials.
Methods
This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5âĂâ1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1â-ârelative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674.
Findings
Between April 23 and Nov 4, 2020, 23â848 participants were enrolled and 11â636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0â75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4â97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8â80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74â341 person-months of safety follow-up (median 3·4 months, IQR 1·3â4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation.
Interpretation
ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
- Author
- ?ivko Iris
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdi Zakee
- Abdukahil Sheryl Ann
- Abel Lynn
- Abraham Jacinta
- Abrahamson Gail
- Abusamra Yousuf
- Aceto Romina
- Adams Nick
- Adams Peter
- Adebambo Olumide
- Adhikari Neill
- Adhikari Sheetal
- Affleck Julia
- Agha Gloria
- Aghemo Alessio
- Agno Ronan
- Ahmad Norfaizan
- Ain Quratul
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al Enezi Farhan
- Al-Bassam Wisam
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderman Meera
- Aldo Bonizzoni Matteo
- Alegria Ana
- Alessandro CarĂ Gianmarco
- Alexander Brian
- Alexander Peter
- Alfonso Jordan
- Ali Maryam
- Ali Murtaza
- Allam Hayat
- Allen Barbara
- Allen Louise
- Allibone Suzanne
- Almeshhedani Hasham
- AlQahtani Samah
- Alswaidan Lolowa
- Altomy Mohammed
- Al Amri Ali
- Al Qasim Eman
- Amatya Sameena
- Ambrosino Richard
- Anderson Thomas
- Andreae Mark
- Aneman Anders
- Angus Derek C.
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Anne-Laure Fedou
- Anstey Matthew
- Antcliffe David
- Anthony Alpha
- Antoine Marchalot
- Antoine Pierre
- Antoine Studer
- Anumakonda Vikram
- Aparicio Christelle
- Aquino Maia
- Arabi Yaseen M.
- Arachchige Malka
- Aravindan Latha
- Arbane Gill
- Archambault Patrick
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arias Sonia
- Arishi Hatim
- Arnold Donald
- Arnold John
- Arnott Andrew
- Arora Anand
- Aryal Diptesh
- Asghar Adeeba
- Asif Namra
- Aspinwall Angelique
- Attokaran Antony
- Attwood Ben
- Au Carly
- Audry Mathilde
- Austin Karen
- Austin Pauline
- Auvet Adrien
- Avard Bronwyn
- Awan Sidra
- Ayee Robert
- Azaiz Amine
- Azzaui Harun
- Babu Suresh
- Bacon Gina
- Badalamenti Salvatore
- Badie Julio
- Bagavathy Kavitha
- Bagot Catherine
- Bagshaw Sean
- Baig Nadia
- Baikady Ravishankar
- Bailey Lucy
- Baillie Kenneth
- Bain William
- Baker Alice
- Baker Evelyn
- Baker Stuart
- Bakthavatsalam Dhanalakshmi
- Balaie Morteza
- Balls-Burgess Sam
- Bamford Amy
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbash Ian
- Barber Russell
- Barbier François
- Barge Deborah
- Bariola Ryan
- Barker Gareth
- Barker Stephanie
- Barnes Nicky
- Baron Rebecca M.
- Barreau Amelie
- Barreau Amélie
- Bart Robert
- Bartholomew Jazz
- Bartley Shauna
- Barton David
- Barton Frances
- Bashyal Archana
- Basile Kim
- Bass Frances
- Bassford Christopher
- Bastos Joana Margarida Pereira Sousa
- Bates Michelle
- Bates Samantha
- Batista Teresa Margarida Oliveira
- Bauchmuller Kris
- Bayne Madeleine
- Bean Sarah
- Beane Abi
- Beane Abigail
- Beard Gregory
- Beasley Richard
- Beaudoin Rosalie
- Beavis Sarah
- Beddows Seonaid
- Bedford Caroline
- Beer Deborah
- Beer Sally
- Begin Phillipe
- Begum Salma
- Bell Gillian
- Bellemare David
- Belletti Allesandro
- Bendjemar Lynda
- Benettaib Fatna
- Bensen Nicole
- Bentley Andrew
- Benyon Sarah
- Benzekri Dalila
- Beqai Besa
- Berdaguer Fernando
- Beresford Stephanie
- Bergin Colin
- Berry Lindsay R.
- Berry Scott
- Berryman Emily
- Bertel Melanie
- Best-Lane Janis
- Besten Henny
- Bevan Emily
- Bewley Jeremy
- Beyerl Ashley
- Bhagani Sanjay
- Bhandal Khushpreet
- Bharaj Kiranjit
- Bhattarai Bina
- Bhattarai Binita
- Bhonagiri Deepak
- Biddie Simon
- Bigas Judit
- Bihari Shailesh
- Bin Hasan Mohd Shahnaz
- Bindels Manon
- Binnie Alexandra
- Biradar Vishwanath
- Birch Catherine
- Birch Janine
- Birch Sophie
- Birchall Kathrine
- Birkinshaw Isobel
- Black Ethel
- Blackledge Bethany
- Blakemore Hayley
- Blanck Wendy
- Bland Yvonne
- Blank Elisabeth
- Bleasdale John
- Bloomfield Jack
- Bloos Frank
- Board Jasmin
- Boardman Melanie
- Boari Gianluca
- Bocher Simon
- Bociek Aneta
- Boivin Anne-Helene
- Boivin Anne-HĂ©lĂšne
- Bojunga Jörg
- Bomken Charlotte
- Bonaccorso Allesandra
- Bongaerts Katherine
- Bonner Stephen
- Bonten Marc J. M.
- Borgatta Barbara
- Borislavova Borislava
- Borrill Zoe
- Boschert Catherine
- Bossard Isabelle
- Bothma Pieter
- Boudineau Michel
- Boulanger Marie-Claude
- Boumahni Dounia
- Bouman Angela
- Bounab Rania
- Bourgoin Charlotte
- Bourne Michelle
- Bourne Richard
- Boutin Mireille
- Bouvier Elodie
- Bouw-Ruiter Marianne
- Boué Yvonnick
- Bowen James
- Bowler Helen
- Boyd Craig
- Boyles Rebecca
- Bracke Stephanie
- Bradbury Charlotte A.
- Bradley Paul
- Brady Kara
- Brailsford Jane
- Brain Matthew
- Brakké Karen
- Brant Emily
- Brasselet Aurélie
- Breen Patrick
- Bremmer Pamela
- Brend Morwenna
- Brennan Aoife
- Bretagnol Anne
- Brett Stephen
- Brewer Chris
- Brickell Kathy
- Bridges Sarah
- Brieger Klaus-Gerd
- Brightling Chris
- Brimfield Lutece
- Brittain Michael
- Britton Kate
- Brochard Laurent
- Brodbeck Andreas
- Brohi Farooq
- Brooks Nicole
- Brown Cynthia
- Brown Julia
- Brown Louise
- Brown Nerissa
- Brown Zarah
- Brugman Curt
- Brunetta Enrico
- Brunkhorst Frank M.
- Brunskill Nigel
- Bryan-Morris Kayla
- Bryden Emma
- Budd Joanna
- Buehner Ulrike
- Buhay Megan
- Buhr Heidi
- Burbee Dylan
- Burda Dorota
- Burgess Richard
- Burke David
- Burke Tara
- Burkey Jason
- Burnish Rachel
- Burns Dean
- Burns Karen
- Burrell Aidan
- Burt Karen
- Buscher Hergen
- Butler Amelia
- Butler Magdalena
- Butler Susan
- Buxton Meredith
- Buzgau Adrian
- Byrne Kathleen
- Byrne Rahim
- Cabrelli Louise
- Cabreros Leilani
- Cairns Tom
- Calfee Carolyn
- Callahan Jean-Christophe
- Cambalova Lenka
- Campbell Andrew
- Campbell Bridget
- Campbell Debbie
- Campbell Hilary
- Campbell Lewis
- Campbell Marion
- Campbell Ryan
- Campion Alexandra
- Campisi Josie
- Camsooksai Julie
- Caplin Cecile
- Carbonneau Elaine
- Carmichael Samantha
- Carmona Rosario
- Carn Vanessa
- Carpio Lillian
- Carr Zoe
- Carr-Wilkinson Joanne
- Carrier François
- Carrier Marc
- Carter Angus
- Carter Brittney
- Carter David
- Carter Jay
- Carter Michael
- Casali Sherry
- Casey Ruth
- Casey Siobhan
- Castelain Vincent
- Castle James
- Cathcart Susanne
- Catorze Nuno José Teodoro Amaro dos Santos
- Cattelan Jessy
- Cavayas Alexandros
- Cawley Kathryn
- Cecconi Maurizio
- Centofanti John
- Chambers Emma
- Champanerkar Shreekant
- Chan Carmen
- Chan Charles
- Chan Peter
- Chapman Rachel
- Chapman Susan
- Charles Bethan
- Charles Walton
- Charlewood Richard
- Charlton Sam
- Charron Cyril
- Chartier Delphine
- Chasse Michael
- Chassé Michaël
- Chen Jonathan
- Chen Lixian
- Chen Yan
- Cheng Allen C.
- Cherian Shiney
- Chhablani Manish
- Chin Teri
- Chudeau Nicolas
- Chukkambotla Sri
- Ciccarelli Michele
- Cirstea Emanuel
- Clair Bernard
- Clark Amy
- Clark Michele
- Clark Richard
- Clark Sarah
- Clarke Frances
- Clarke Jennifer
- Claxton Andrew
- Cleary Joanne
- Clement Ian
- Clere-Jehl Raphael
- Clermont Giles
- Clermont Gilles
- Clinton Alison
- Cloutier Ăve
- Cockrell Maeve
- Codreanu Daniel
- Coetzee Samantha
- Coghlan Phoebe
- Cole Jade
- Coles Jennifer
- Colin Gwenhael
- Collier Dawn
- Collins Amy
- Collins Daniel
- Collins Emma
- Collins Joanne
- Collins Ărin
- Collis Matthew
- Combaux Daniele
- Commons Robert
- Comp Susan
- Concha Pablo
- Connolly Karen
- Constantini Elena
- Constantino-Occhipinti Claudia
- Contou Damien
- Convery Karen
- Conway Robert
- Conzelmann Nadine
- Cook Deborah
- Cook Tim
- Cooke Jill
- Cooke Justin
- Cooper Jamie
- Cooper Josh
- Cooper Lauren
- Cooper Melanie
- Cooper Nichola
- Corbett Sarah
- Corcoran Ele
- Corcoran Kathleen
- Cornell Sarah
- Cornell Thomas
- Cort Jon
- Costerousse Olivier
- Couillard-ChĂ©nard Ămilie
- Courtin Laura
- Coutts Amanda
- Couture Lourie
- Cove Matthew
- Cowdrey Keri-Anne
- Cowley Nicholas
- Cowton Amanda
- Coyne Mark
- Craddock Richard
- Craner Michelle
- Craven Thomas
- Crawshaw Sarah
- Creagh-Brown Ben
- Creange Vanessa
- Cremer Olaf
- Crisp Nikki
- Croft Maria
- Csabi Peter
- Cudlipp Joanna
- Cuesta Jeronimo
- Cuffaro Raffaele
- Curley Gerard
- Currie Andrew
- Cusack Rebecca
- Cuthbertson Brian
- Cutler Sean
- CĂĄrcel Sheila
- CĂŽtĂ© Ămilie
- D?Amato Fabiola
- D?Aragon Frédérick
- Daebis Admad
- Daher Rana
- Dale Katie
- Daley Jessica
- Dalton James
- Daly James
- Daly Zoe
- Daneman Nick
- Dark Paul
- Darnell Robert
- Darreau Cedric
- Daugherty Jason
- Davey Miriam
- Davidson Neil
- Davies Ellie
- Davies Gwyneth
- Davies Jennifer
- Davies Louisa
- Davies Michelle
- Davies Rhys
- Dawson Laura Ann
- Dawvda Ashlish
- Day Christopher
- Da Rocha Joana
- De Bus Liesbet
- de Courcy-Golder Kim
- de Groot Klaas
- de Jong Menno
- de Jonge Evert
- De Keulenaer Bart
- de la Torre Cisneros Julian
- de Man Angelique
- De Neef Mark
- De Smeytere Anouska
- Deacon Bethan
- Dean Steven
- Dean Tessa
- Dearden Joy
- Dechert William
- Declercq Pierre-Louis
- Degracia Anna
- del Sorbo Lorenzo
- Dela Rosa Arnold
- Delaney Kirsha
- Dell Abbie
- del Prado Michael
- Demetriou Carrie
- Dempster Debra
- Denham Lynn
- Denmade Craig
- Dent Martin
- Depante Maria
- Depuydt Pieter
- Dequin Pierre-François
- Derde Lennie P. G.
- Deshpande Kush
- Detry Michelle A.
- Deye Nicolas
- de la Fuente Carmen
- De Waele Jan
- Dheke Krishan
- Di Lucca Giuseppe
- Dias Priya
- Dice Julie
- Digby Stephen
- Diridis Kristina
- Distler Michael
- Dobell-Brown Kelsey
- Doble Patricia
- Dobson Jade
- Doherty Kaleigh
- Doherty Ronan
- Doi Yohei
- Dolman Rozzie
- Domingo-Marco Joana
- Donadee Chenell
- Donaldson Kate
- Dondrop Arjen
- Donegan Clare
- Donlon Sinead
- Donnelly Adrian
- Donnelly Kieran
- Donnison Phil
- Doonan Reece
- Doran Peter
- Dore Rachael
- Dormand Natalie
- Dos Santos Filipa
- Douillard Thomas
- Drake Chelsea
- Drapola Debra
- Drayss Maria
- Drummond Andrew
- Drury Kay
- Duan Erick
- Duberley Stephen
- Duffy Eamon
- Duffy Oscar
- Duke Graeme
- Duke Zoe
- Duncan Tracy
- Dunsavage Janice
- Duplaix Mathilde
- Duric Natalie
- Duroux Maree
- Dushianthan Ahilanandan
- Dyas Sarah
- Eapen Beena
- Eastgate Christine
- Ebenezer R
- Edmunds Natasha
- Edwards Alexandra
- Efford Georgia
- Egreteau Pierre
- Ehrmann Stephan
- Eichenauer Dennis
- Eisenbeis Simone
- Ekhérian Jean-Michel
- El-Khawas Khaled
- Elender Corinna
- Elgendy Ahmad
- Elhassan Munzir
- Ellervee Anneli
- Ellis Chiara
- Ellis Christine
- Ellis Yvette
- Elmahi Einas
- Elsefi Tarek
- Eltayeb Ayaa
- Elvira Evangeline
- England Jenna
- Englert Sarah
- English Shane
- Epelmanž Slava
- Eroglu Ege
- Estcourt Lise J.
- Estensen Kristen
- Evans Amy
- Evans Andrew
- Evans Debra
- Evans Gabrielle
- Everitt Robert
- Evers Mirjam
- Evetts George
- Ewalds Esther
- Ezekowitz Justin
- Fagan Laura
- Fagbodun Elizabeth
- Farahi Neda
- Fareed Komal
- Farnell-Ward Sarah
- Fartoukh Muriel
- Faulkner Beverley
- Faulkner Maria
- Fazla Fathima
- Featherstone Peter
- Felton Tim
- Fennessy Gerard
- Ferguson Niall
- Ferguson Susan
- Fergusson Dean
- Fernandes Edna
- Fernandez Maria
- Fernando Gloria
- Fernåndez de Pinedo Artaraz Ziortza
- Ferreira Ricardo Manuel Castro
- Ferrier Janet
- Ferringer Cindy
- Fesz Jessica
- Fierens Jan
- Finch Cheryl
- Finn André
- Finn Stephanie
- Finnis Mackenzie
- Fiouni Sofia
- Fischer Roy
- Fitzgerald Mark
- Fitzpatrick Meghan
- Fletcher Simon
- Flint Neil
- Flor Thomas
- Florescu Simin
- Fluher Jure
- Flynn Gordon
- FocĂ Emanuele
- Folci Marco
- Forbes Andrew
- Ford Megan
- Forster Elliot
- Foster Tracy
- Fottrell-Gould Deirdre
- Foulds Angela
- Fowler Rob
- Fowler Robert
- Fox Claire
- Fox Eleonore
- Fragner Gertrud
- Frakking Thuy
- Franch-LLasat Diego
- Francis Olesya
- Francoeur François
- Francois Bruno
- Frankfurter Claudia
- Franz Christopher
- François Bourgerol
- Fraser Catherine
- Frater Alasdair
- French Craig
- Frey Anna
- Frey Christian
- Frise Matthew
- Frost Victoria
- Fuchs Ralph
- Fujitani Shigeki
- Fysh Ed
- Gachet Alexandre
- Galbiati Carola
- Galea James
- Ganesan Arunkumar
- Ganesan Manisha
- Ganguly Saibal
- Garcia Sara
- Gardiner-Hill Caroline
- Garot Denis
- Garrard Hywel
- Garrard William
- Garrett Peter
- Garrier Ludivine
- Garrod Esther
- Garton Mark
- Garvey James
- Gascoyne Rachel
- Gattas David
- Gauli Basanta
- Gay Alexandra
- Gaylard Jane
- Gellamucho Minerva
- Gemmell Lisa
- Gendall Emma
- Geng Wenli
- Geoghegan Pierce
- Geri Guillaume
- Geurts Heidi
- Ghaffari Mehrdad
- Ghamraoui Ali
- Ghattaoraya Amardeep
- Ghosh Alison
- Giardina Giuseppe
- Gibbins Alexandra
- Gill Mandy
- Gilliam Matthew
- Gilmour Kate
- Girard Timothy
- Girijadevi Dinuraj
- Gladas Kirsty
- Glasby Kathleen
- Gledhill Lisa
- Glister Georgina
- Glynou Loukia
- Goddard Wendy
- Godement Mathieu
- Godoy Lucas C.
- Goebeler M.E.
- Golden David
- Goldman John
- Goligher Ewan
- Gomez Keith
- Gommans Frank
- Goodwin Jayne
- Goossens Herman
- Gopal Shameer
- Gopinath Amitha
- Goralski Patricia
- Gordon Anthony C.
- Gosbell Iain
- Gould Richard
- Grady Bart
- Graham Cheryl
- Graham Libby
- Graniewski Jaroslaw
- Grant Caroline
- GrauNovellas Neus
- Greco Massimiliano
- Grecu Irina
- Green Cameron
- Green Jackie
- Greene Emma
- Greener Danni
- Gregory Jane
- Gresham Rebecca
- Greven Frances
- Grieve Richard
- Grimm Patrick
- Grimmer Lisa
- Groeneveld Erika
- Gross Jamie
- GrĂŒnewaldt Achim
- Guanco Mark
- Guerineau Elodie
- Guitton Christophe
- Gummadi Mahitha
- Gupta Abhinav
- Gurung Anita
- Guérin Emmanuelle
- GĂłmez Francisco
- Göpel Siri
- Habeichi Wadih
- Habraken Hannah
- Hadebe Bernard
- Haffiane Abdelmagid
- Hagel Stefan
- Haghi Theerata
- Haiba Khalid
- Haidar Ghady
- Haider Nafeesah
- Haider Syeda
- Hajdu Bence
- Hakak Sheeba
- Halden Sandra
- Haldeos Anne
- Hall Alistair S
- Hall Amelia
- Hall Andrew
- Hall Kathryn
- Hall Rebecca
- Hamilton David
- Hamilton-Davies Colin
- Hamlyn Vincent
- Hammond Naomi
- Hammonds Fiona
- Hand James
- Haniffa Rashan
- Hanisch Alexis
- Hanley Joanne
- Hansen Dan
- Hanson Helen
- Hanson Jane
- Harden Lesley
- Harding Daniel
- Hardy Chloe
- Harford Rachel
- Harland Cain
- Harper Heather
- Harrington Claire
- Harrington Kate
- Harris Celia
- Harris Jade
- Harris John
- Harrison David A.
- Harrison Susan
- Harrow Kath
- Hartley Melissa
- Harvala-Simmonds Heli
- Harvey Alice
- Harvey Daniel
- Harvey James
- Harward Meg
- Hashmi Madhia
- Hashmi Madiha
- Hassan Noor
- Hausermann Marie-Helene
- Hawcutt Daniel
- Hawes Joanne
- Hawkins Nancy
- Hay Sophie
- Haydon Tim
- Hayes Amber
- Hayes Anne
- Hayes Kati
- Hayes Leanne
- HC Ooi
- Headdon William
- Headlam Evie
- Healey Gail
- Hegazy Ahmed
- Hegazy Mohamed
- Heinonen Jonna
- Helms Julie
- Heming Nicholas
- Henderson Kelly
- Henderson Steven
- Henning Jeremy
- Henri-Lagarrigue Matthieu
- Henry Joanne
- Henry Lavinia
- Hensley Joseph
- Heritier Stephane
- Hernandez Erik
- Hewitt Claire
- Hey Samuel
- Hickey John
- Hierons Sarah
- Higgins Alisa M.
- Hill Claire
- Hill Dianne
- Hill Helen
- Hilldrith Anette
- Hills Thomas
- Hin Lui Lok
- Hindle Grace
- Hinrichs Carl
- Hird Clare
- Hodge Christopher
- Hodgson Carol
- Hodgson Helen
- Hoff Uwe
- Hoiting Oscar
- Holbrook Catherine
- Holland Andrew
- Holland Nicky
- Holland Susan
- Hollos Laszlo
- Homes Jennifer
- Honda Hitoshi
- Hope David
- Hopkins Phil
- Hormis Anil
- Horner Dan
- Hornsby James
- Horton Michelle
- Horvat Christopher M.
- Howcroft Clare
- Howell Alice
- Hower Martin
- Howie Lucy
- Howle Ryan
- Hoxha Elvira
- Huang David T.
- Hughes Debbie
- Hugill Keith
- Huijbens Danique
- Hullegie Sebastiaan
- Hulley Amanda
- Hulme Jonathan
- Hulse Sarah
- Humphrey Charlotte
- Hunt Beverley
- Hunter Stephanie
- Hurford Sally-Anne
- Hussain Mahwish
- Hussain Sajid
- Hutchinson Christina
- Hutton Paula
- HĂŒning Vanessa
- Ichihara Nao
- Ijaz Nazia
- Ikhena Ikhuemose
- Inskip Deborah
- Irving Ben
- Isgro Graziella
- Isguzar Agah
- Ishani Pramodya
- Ivatt Helen
- Jackson Carolyn
- Jackson Shane
- Jackson Susan
- Jacob Reni
- Jacquier Sophie
- Jafarzadeh Mina
- Jagannathan Vijay
- Jain Susan
- James Augustian
- James Christie
- Jan Hassing Robert
- Janin Pierre
- Jarczak Dominik
- Jarman Claire
- Jayakumar Deva
- Jayakumar Devachandran
- Jean-Pierre Eraldi
- Jeblaoui Asma
- Jenkins Samuel
- Jenkins Sarah
- Jenkins Steve
- Jennings Stacey
- Jepson Eleanor
- Jerenec Katja
- Jesty Robert
- Jha Avinash
- Jha Rajeev
- Jhanji Shaman
- Jin Xia
- Jindai Kazuaki
- John Maya
- Johns Magaret
- Johnson David
- Johnson Paul
- Johnson Rebekah
- Johnson Toby
- Johnston Brian
- Jones Andrea
- Jones Cathy
- Jones Dawn
- Jones Emily
- Jones Jessica
- Jones Samantha
- Jongebloed Katherine
- Joseph Sibet
- Joseph Treesa
- Joyce Kirsten
- Juffermans Nicole
- Juhaz Vera
- Kadam Umesh
- Kalamar ?iga
- Kalchko-Veyssal Selver
- Kalchthaler Kyle
- Kaliappan Agilan
- Kalla Ismail
- Kalogirou Michael
- Kamata Kazuhiro
- Kamel Toufik
- Kampschreur Linda
- Kamra Maneesha
- Kandeepan Revathi
- Kannan Santhana
- Kannan Thogulava
- Kanwal Darakhshan
- Karachi Tim
- Karim Hina
- Karki Rakshya
- Karlikowski Michal
- Karlsson Sari
- Kasipandian Vidya
- Kassir Sandy
- Katary Amro
- Kato Hideaki
- Kavanagh Lisa
- Kayani Abdul
- Kayastha Srijana
- Kaye Callum
- Kazi Aayesha
- KC Shirish
- KC Shirsh
- Keating Liza
- Keatley Claire
- Keeler Sheryl
- Keen Alexandra
- Keen Sherbrina
- Keijzer-Timmers Nicole
- Kell Kay
- Kelly Martin
- Kelly Niamh
- Kelsall Olivia
- Kendrick Sara
- Kernan Maeve
- Kerslake Ian
- Kester Esmee
- Khade Reena
- Khalid Imrana
- Khan Meherunnisa
- Khanal Kishor
- Khanal Sushil
- Khare Divya
- Khoso Nasir
- Khoud Ahmed
- Khwaja Kosar
- Kidwai Aneela
- Kiiski Heikki
- Kilner Mari
- Kim Edy Y.
- Kimpton Sarah
- King Andrew
- Kinney Fiona
- Kirk Jill
- Kirk Rosemary
- Kirkby Amy
- Kirkham Simon
- Kit Barbara
- Kitsios Georgios
- Kittridge Lauren
- Klein Daniela
- Klop-Riehl Margreet
- Kluge Stefan
- Knowles Karen
- Kochanek Matthias
- Kochert Erik
- Koelink Maaike
- Koirala Kanchan
- Koirala Sabin
- Kolanos Steffi
- Kolovou Angeliki
- Konecny Pam
- Kong Jing
- Koopmans Matty
- Kosa Alma
- Kremling Julius
- KreĂ Gabriele
- Krishnamoorthy S
- Krishnamurthy Vinodh
- Kruger Peter
- Kruisdijk-Gerritsen Arriette
- Kruisselbrink Rebecca
- Kuitunen Anne
- Kumar Anand
- Kumar Nikhil
- Kumar Rohit
- Kummerlen Christine
- Kunishima Hiroyuki
- Kunwar Puja
- Kunz Kevin
- Kurenda Catherine
- Kutsogiannis Demetrios
- Kuybida Yuriy
- Kwan Yvonne
- Kyeremeh Lynsey
- Kyle Laura
- L?Hotellier Sylvie
- Labbe Vincent
- Laffan Mike
- Laffey John
- Laha Shondipon
- Lai Vivian
- Lambert Bridget
- Lamontagne Francois
- Lampro Lamprini
- Landais Michaël
- Landoni Giovanni
- Landsiedel-Mechenbier Elke
- Lang Eva
- Langridge Emma
- Latham Victoria
- Latino Reece
- Laudi Svenja
- Laugs Fabian
- Lavana Jayshree
- Laver Russell D.
- Law Daniel
- Lawler Patrick R.
- Le Basnier Elliot
- Le Guen LenaĂŻg
- Le Loup Guillaume
- Leaf David E.
- Lean Richard
- Leaver Susannah
- Leavis Helen
- Leblond Julie
- Leditschke Anne
- Lee Kelvin
- Lee Stephanie
- Lee Stephen
- Lefevre Montaine
- Leffelaar Evelien
- Lehalleur Adrien
- Lellouche Francois
- Lemaire-Brunel Delphine
- Lembo Rosalba
- Leparco CĂ©cile
- Leroyer Marie-Helene
- Lesona Eden
- Levett Chris
- Lewis Joanne
- Lewis Roger J.
- Lewis Sarah
- LewisProsser Lorraine
- Liao Angela
- Lim Rosario
- Limb James
- Lindergard Gabriella
- Linnett Vanessa
- Linstrum Kelsey M.
- Litton Ed
- Litton Edward
- Liu Theresa
- Lizotte Patricia
- Lock Stephen
- Lockett Teresa
- Logan Meg
- Lomme Kaatje
- Long Matilda
- Lopus Alyssa
- Lorenzi Elizabeth
- Lother Sylvain
- Lowe Benjamin
- Lowery Maryalyce
- Lowrey Julie
- Lucas Rachael
- Luis David
- Luitel Subekshya
- Luk Tracy
- Lunde Ragnar
- Luo Ji
- Lye Alison
- Lynch Ceri
- Lynch Daniella
- LĂłpez Maria
- LĂłpez Rafael
- Löbel Madlen
- MacKay Callum
- Mackay Euan
- Mackay Josephine
- MacKay Lynn
- Mackenzie Brittney
- Mackintosh Katherine
- MacLennan Sheila
- MacTavish Pamela
- Madani Yasser
- Madarbukus Daanyaal
- Maharajh Amitaa
- Maharjan Mili
- Maharjan Radhika
- Maharjan Sabi
- Maiden Matthew
- Mailman Jonathan
- Major Emmet
- Makanju Esther
- Makky Ahmed
- Makowski Arystarch
- Malakouti Salim
- Male Michelle
- Malfroy Sylvain
- Mali Sharmila
- Malissin Isabelle
- Malley Brian
- Maloney Carolyn
- Maloney Gracie
- Mandadapu Vineela
- Mani Ashwin
- Manley Rachel
- Manoharan Venika
- Maquigneau Natacha
- Marchesi Mattia
- Mariappa Vasanth
- Marin-Corral Judith
- Marin?ek Martin
- Marinoff Nicole
- Marion Beuzelin
- Markota Andrej
- Marmol Joy
- Marnai Remy
- Marriot Cheryl
- Marriott Yvonne
- Marroquin Oscar
- Marsden Tracy
- Marsh Emma
- Marshall John C.
- Marshall Lucy
- Marten Nicole
- Martin Elise
- Martin Emma
- Martin Jane
- Martin Laila
- Martin Timothy
- Martin-Lazarro Juan
- Martinez Maria
- Martucci Antonio
- Martynoga Robert
- Mary-Genetu Roman
- Mascherpa Glenda
- Masdeu-Eixarch Gaspar
- Maselli Astrid
- Mason Alexina
- Mason Brittany
- Masood Sobia
- Massar Brent
- Masse Marie-Helene
- Massey Natalie
- Masters Kristy
- Mataliotakis Michail
- Mathew Meghena
- Mathew Moncy
- Mathonnet Armelle
- Matimba-Mupaya Wadzanai
- Matsa Ramprasad
- Matthews Julie
- Maxime Virginie
- Mayak Katelyn
- Mayangao Irving
- Maynard Victoria
- Mayr Florian
- Mc-Kenzie Josette
- McAdams David
- McArthur Colin J.
- McAuley Daniel F.
- McAuley Julie
- McCallion Edmund
- McCarthy Aine
- McClintock Declan
- McConnochie Rachael
- McCracken Phoebe
- McCreary Erin
- McCreath Gordan
- McCullagh Iain
- McCullagh Liz
- McCulloch Corrienne
- McCullough James
- McDonald Bree
- McDyer John
- McEldrew Ben
- McEldrew Rebecca
- McEvoy Natalie
- McGain Forbes
- McGarry Karen
- McGhee Christopher
- McGlothlin Anna
- McGloughlin Steve
- McGlynn Deborah
- McGoldrick Clare
- McGuigan Peter
- McGuinness Shay P.
- McIntyre Joanne
- McIntyre Lauralyn
- McKee Madeleine
- McKenna Shirley
- McKenna Sonia
- Mckeon Laurie
- Mclaughlan Danielle
- McMaster Moyra
- McMillan Alexandra
- McMillan Catherine
- McMillan Helen
- McMorrow Liam
- McNamara Amanda
- McNamara Robert
- McNicholas Bairbre
- McQuilten Zoe
- McVerry Bryan J.
- McWilliam Stephen
- Medhurst Laura
- Medva Rebecca
- Meermeier Werner
- Megarbane Bruno
- Mehrtens Jan
- Mehta Reena
- Meijer Karina
- Menon David
- Mercier Emmanuelle
- Mercier Romain
- Merdji Hamid
- Meredith Megan
- Metherell Stella
- Meunier Juliette
- Mevavala Bhaumik
- Mew Louise
- Meyer Jason
- Mezher Chaouki
- Meziani Ferhat
- Mfuko Celina
- Mguni Nhlanhla
- Michael Angiy
- Michalak-Glinska Natalia
- Middledorp Saskia
- Miezitis Sydney
- Mikusek Justyna
- Mila de la Fuente Gema
- Miles Helen
- Millen Tina
- Miller Amanda
- Miller Jennene
- Miller Lorna
- Mills Gary
- Miln Rebecca
- Minnier Tami
- Mistry Deena
- Misztal Beata
- Mitchard Sarah
- Moakes Emma
- Moghbeli Kaveh
- Mohammed Amal
- Moine Pierre
- Mokhtar Nabih
- Monaghan Holly
- Monaghan Maree
- Monchi Mehran
- Moneger Guy
- Monnier Alexandra
- Monzon Angelica
- Moore Lorraine
- Moore Vanessa
- Moorhouse Louise
- Morel Guillaume
- Morgan Karen
- Morgan Matt
- Morgan Stacey
- Morpeth Susan
- Morris Anna
- Morris Jenny
- Morris Lucy
- Morris Sheila
- Morrison Lynette
- Mouncey Paul R.
- Mowery Brent
- Mrad Aymen
- Mtuwa Shelia
- Mukherjee Dipak
- Mulder John
- Mulier Jelle
- Mulla Suleman
- Mullan Dee
- Muller Grégoire
- Munt Sheila
- Murphy Aisling
- Murphy Lorna
- Murphy Peter
- Murphy Ryan
- Murphy Sheenagh
- Murray Andrew
- Murray Lauren
- Murray Lyle
- Murthy Srinivas
- Music Edvin
- Muteithia Margaret
- Muvindi Himasha
- Muzengi Natasha
- Muñoz-BermĂșdez Rosana
- Mwaura Esther
- Mwembani Tina
- Naeem Anas
- Naidu Brintha
- Naim Giulia
- Nair Priya
- Nakamuro Hiromi
- Nakazono Kenichi
- Nakhnoukh Cristina
- Nand Kiran
- Nandani Aarti
- Navarra Leanlove
- Nay Mai-Anh
- Nayyar Vineet
- Naz Mobeena
- Neal Matthew
- Nee Jens
- Neill Andy
- Nelli Apoorva
- Nemeth Christopher
- Nemeth-Roszpopa Karolina
- Netea Mihai
- Netherton Kimberley
- Neto Ary
- Newbould David
- Newlands Jessica
- Newman Julie
- Newman Tabitha
- Ng Anthony
- NG Christopher
- Nguyen Philippe
- Nguyen-Valat Thi-My-Hue
- Nichol Alistair D.
- Nicholier Tiphaine
- Nicholson Andrew
- Nicholson Anne
- Nicholson Sarah
- Nickoleit-Bitzenberger Daniela
- Nierhaus Axel
- Nikitas Nikitas
- Noble Harriet
- Noel-Hunter Monia
- Nolan Jerry
- Nordin Nazril
- North Julie
- Nortje Jurgens
- Nourse Mary
- Nown Angie
- Nygren Maria
- O Rourke Kate
- O'Connell Martin
- O'Kell Eleanor
- O'Neill Lorraine
- O'Neill Stephen
- O'Reilly Joanna
- O?Brien Julie
- O?Brien Neale
- O?Connor Aibhilin
- O?Connor Anne
- O?Connor Caroline
- O?Connor Stephanie
- O?Dwyer Michael
- O?Halloran Sinead
- O?Kane Cecilia
- O?Kane Sinéad
- O?Leary Ryan
- O?Malley Laura
- O?Neill Aisling
- O?Reilly Kevin
- Oakley Susan
- Oborska Aneta
- Occhipinti Giovanna
- Ochin Evelina
- Oczkowski Simon
- Ogg Bethan
- Ogungbenro Kayode
- Okubanjo Maryanne
- Okundaye Clementina
- Oliver Anne
- Oliver Martyn
- Omer Nimca
- Oncea Lynne
- Orford Neil
- Oritz-Ruiz de Gordoa Laura
- Orlikowska Izabela
- Orlikowski David
- Orr Katrina
- Osagie Rawlings
- Osborne Alexander
- Osborne Jason
- Osinga Margreet
- Ostermann Marlies
- Ottens Thomas
- Owen David R. J.
- Oza Deepali
- Padmakumar Anand
- Page Shannon
- Page Valerie
- Pakats Mari-Liis
- Pakou Glykeria
- Palermo Annamaria
- Paneru Hem
- Panjwani Ashok
- Panwar Rakshit
- Pappa Evita
- Paramasivam Elankumaran
- Parekh Dhruv
- Parikh Harshel G.
- Parke Rachael L.
- Parker Jane C.
- Parker Lorraine
- Parker Natasha
- Parmar Dinesh
- Parry-Billings Karen
- Parsons Penny
- Pasieka Bastian
- Patanwala Asad
- Patawala Asad
- Patch Sarah
- Patel Amit
- Patel Bijal
- Patel Brijesh
- Patel Kamal
- Paterson David
- Pathak Shreya
- Patil Sonal
- Patterson Lisa
- Paudel Pratibha
- Peake Sandra
- Pearson Harriet
- Pearson Karen
- Pech Yadira
- Pegler Suzannah
- Pellicano Susan
- Pemberton Abigail
- Pendlebury Jessica
- Pereira Rita
- Pereira Tiago Nuno Alfaro Lima
- Perez Jane
- Perri Reno
- Peters Anna
- Peters Cecilia
- Peters Marco
- Peters Sam
- Peters Svenja
- Petros Sirak
- PettilÀ Leena
- PettilÀ Ville
- Phalod Gunjan
- Philbin Jennifer
- Philip Annlin
- Philippe Rigaud
- Phillips Barbara
- Phillips Matt
- Phua Jason
- Phull Mandeep-Kaur
- Phuyal Aarti
- Pickering Charlotte
- Pickkers Peter
- Piercy Charlie
- Pietersma Mario
- Pillai Suresh
- Pinder Meredith
- Pinnell Jez
- Pinto Marta
- Pitts Sally
- Piva Simone
- Plantefeve Gaetan
- Platenkamp Ellen
- Plesnikova Yvonna
- Pletz Mathias
- Plummer Bethany
- Plummer Mark
- Pogreban Tatiana
- Pogson David
- Polfliet Margot
- Polgarova Petra
- Polley Grace
- Pollock Katrina M.
- Pomeroy Fiona
- Poojara Latesh
- Pooni Jagtar- Singh
- Porteous Rebecca
- Porter David
- Postlethwaite Kelly
- Postma Douwe
- Potter Alison
- Potter Sarah
- Poulter Amber-Louise
- Poupblanc SĂ©verine
- Pouplet Caroline
- Pourcine Franck
- Povoa Pedro
- Powell Elizabeth
- Prabakaran Rajalakshmi
- Pradel Gael
- Pratheema Ramachandran
- Prebeg Katharina
- Preijers Lieke
- Presneill Jeffrey
- Pridee Nicole
- Prinssen Anton
- Pritchard Kelly
- Proudfoot Nicola
- Prout Rachel
- Pugh Richard
- Purandare Laura
- Purnell Rebecca
- Purohit Dharam
- Purvis Sarah
- Puskarich Michael
- Putensen Daniel
- Puthucheary Zudin
- Puxty Kathryn
- PĂ©rez-TerĂĄn PurificaciĂłn
- PÔldots Liisi
- Qiu Shan
- Qiu Xinyi
- Quayle Rachael
- Quenot Jean Pierre
- Quinn Alison
- Quinn Kevin
- Qureshi Hafiz
- Raczek James
- Rad Laura
- Rademaker Emma
- Rahmani Hassene
- Rai Namrata
- Rai Sabi
- Raithatha Ajay
- Raj Ashok
- Ralston Maximillian
- Ramakrishnan N
- Ramali Mohamed
- Ramamurthi Balaji
- Ramanan Mahesh
- Ramos Angelo
- Ramos Lidia
- Randell Georgina
- Rangan Ritika
- Ranganathan Lakshmi
- Rao Deepak
- Rashan Aasiyah
- Rashan Sumayyah
- Ratcliffe Megan
- Ratnam Valli
- Ravry Celine
- Rawlins Sam
- Reay Michael
- Rebello Rashmi
- Reddy Amie
- Reddy Harsha
- Reed Catherine
- Rees Stephanie
- Reeve Brenda
- Regli Adrian
- Rehman Atique
- Reid Andrew
- Reid Liadain
- Reidy Bryan
- Reill Lorenz
- Reinhard Veronika
- Rengers Els
- Rennit Pille
- Reschreiter Henrik
- Reverté-Villarroya Silvia
- Revill Adam
- Rewa Oleksa
- Reyes Luis Felipe
- Reynolds Bob
- Reynolds Claire
- Reynolds Jessica
- Rhodes Jonathan
- Richards Carol
- Richards Suzanne
- Richards-Belle Alvin
- Richardson Aaron
- Richardson Angus
- Richecoeu Jack
- Riches Joanne
- Ricketts Dan
- Ricketts Daniel
- Riddell Phillip
- Riepe Ansgar
- Rietveld Ilse
- Rimmer Dominic
- Ripa Marco
- Rissen Reimer
- RistimÀki Sanna
- Ritzema Jenny
- Rivett Justine
- Rizzoni Damiano
- Roberts Belinda
- Roberts David
- Roberts Eilir
- Roberts Tracey
- Robertson Debra
- Robinson Matt
- Roche Lisa
- Roche-Campo Ferran
- Rochwerg Bram
- Rodden Natalie
- Rodriguez Marina
- RodrĂguez-GĂłmez Jorge
- Roebers Harald
- Roedl Kevin
- Rohde Gernot
- Rojo Roceld
- Romagnuolo Tina
- Roman Jaime
- Romberg Birgit
- Rook Clare
- Rooney Kevin
- Roovers Noortje
- Rosaroso Lace
- Rosborough Brian
- Rose Steve
- Rosenstein-Sisson Rachel
- Ross Elizabeth
- Rostron Anthony
- Roth Jason
- Rouge Patrick
- Roumen Rudy
- Rounds Charles
- Rovere-Querini Patrizia
- Rowan Kathryn M.
- Rowe-Leete Louise
- Rowland Matthew
- Roy Alistair
- Roynon-Reed Anna
- RueĂ-Paterno Giusi
- Ruiz Winningtom
- Runge Isabelle
- Ruselli Giovanna
- Russo Giada
- Ryalls Kim
- Ryan Donal
- Ryan Lucy
- Sabaretnam Suganya
- Sabelhaus Timo
- Sackrowitz Rachel
- Sadera Girendra
- Sadique Zia
- Sagnier Anne
- Saha Sian
- Saint Martin Marjorie
- Saito Hiroki
- Saiyed Salim
- Salahuddin Nawal
- Salberg Armorel
- Saleem Malik
- Salhi Sara
- Sall Jas
- Salmon Charlotte
- Salmon Karen
- Saluja Rupali
- Saluzzio Romina
- Salvati Stefano
- Sampson Julia
- Sanders Arnate
- Sanderson Amanda
- Sandhu Gyan
- Sanghavi Ritesh
- Santamaria John
- Santos Filipa
- Santos Marlene S.
- Sapsford David
- Sara Treena
- Saran Anita
- Sathe Sonia
- Sathianathan Kushaharan
- Sathianathan Prasannakumari
- Saull Michelle
- Saunders Christina T.
- Saunderson Paula
- Sauras-ColĂłn Esther
- Saxena Manoj
- Sayada Sarah
- Sayehli Cyrus
- Scanlan Jeremy
- Scano Riccardo
- Schaaf Bernhard
- Schlegel Christian
- Schmidhofer Mark
- Schneider Francis
- Schoenling Andrew
- Scholl Denise
- Schotsman Joost
- Schouten Jeroen
- Schueler Robert
- Schuster-Bruce Martin
- Schutgens Roger
- Schweikert Sacha
- Scott Kathryn
- Scott Zoe
- Scully Michael
- Seaman Rebecca
- Seidel Antje
- Seidu Fatima
- Seigne Patick
- Sekiwala Rose
- Sellers Katharine
- Selmi Carlo
- Sement Arnaud
- Senya Ho
- Seppelt Ian
- Sernicola Elisa
- Serri Karim
- Sevilla Chanthou
- Seymour Christopher W.
- Shah Faraaz
- Shahid Tasnin
- Shaikh Arif
- Shaikh Mohiuddin
- Shakya Roshni
- Shankar-Hari Manu
- Sharma Deepak
- Shaw David
- Shaw Deborah
- Shaw Joanne
- Shearer Audrey
- Sheath Ben
- Sheffield Jonathan
- Shehabi Yahya
- Shekar Kiran
- Shelton Sarah
- Sherwood Nick
- Shetty Varun
- Shields Fiona
- Shimabukuro-Vornhagen Alexander
- Shintani Ayumi
- Shirley Kim
- Shovelton Charmaine
- Shree Madhu
- Shrestha Namrata
- Shrestha Sabita
- Shrestha Tapaswi
- Shu Ki Lok Jennifer
- Shyamsundar Murali
- Siami Shidasp
- Sibin Sindhu
- Sicat Christine
- Siddiqui Atif
- Siddiqui Ayesha
- Sidéris Georgios
- Siewerski Chris
- Siika Wangari
- Sikondari Nyma
- Silversides Jon
- Sim Malcolm
- Simmonds Catherine
- Simons Koen
- Simpson Benjamin
- Simpson Joanna
- Simpson Scott
- Simpson Tom
- Sinclair Julie-Ann
- Singh Jayaprakash
- Singh Rajeev
- Singh Vanessa
- Singler Karen
- Singleton Jo
- Sinha Pratik
- Skinner Denise
- Skinner Tabitha
- Skorko Agnieszka
- Skrtich Aimee
- Slaughter Melanie
- Slieker Kitty
- Sligl Wendy
- Sloan Andrew
- Sloots-Cuppen Sonja
- Small Charlotte
- Smallshaw Karen
- Smallwood Andrew
- Smee Joanna
- Smit Albertine
- Smith Alex
- Smith Catherine
- Smith Eleanor
- Smith Emma
- Smith John
- Smith Judith
- Smith Julie
- Smith Kerry
- Smith Lucie
- Smith Matthew
- Smith Natalie
- Smith Oliver
- Smith Paul
- Smith Simon
- Smith Tim
- Smuts Sara
- Smyth Kirsty
- Smyth Michelle
- Smyth Naoise
- Soar Natalie
- Solesbury Amanda
- Somerville Alastair
- Song Rima
- Soukup Jens
- Southern David
- Southin Sara
- Spain Sandra
- Speight Holly
- Spencer Kayleigh
- Spencer Stephen
- Spencer Thomas
- Speyer Rebecca
- Spiers Catriona
- Spittle Nick
- Spivey Michael
- Spong Adam
- Sprinckmoller Stefan
- Squires Rebecca
- Stambaugh Martha
- Stammers Katie
- Stanciu Delia
- Stanley Timothy
- Stanworth Simon
- Stapleton Liana
- Starke Lisa
- Stavor Dara
- Stedman Roger
- Steffen Melanie
- Stephanie Gelinotte
- Stephens Deanna
- Stevenson Lesley
- Stewart Richard
- Stienstra Riejanne
- Stone Sarah
- Stowe Bethan
- Stratton Emma
- Stronach Lucy
- Suber Tomeka
- Sukuraman Anila
- Summerfield Anna
- Summers Charlotte
- Sundaram Radha
- Sundaran Dhinesh
- Sunkara Krishna
- Surti Zuhra
- Sutherland Helen
- Sutherland Sara-Beth
- Sutterlin Laetitia
- Sutton Joanne
- Sutu Mihaela
- Sven?ek Franc
- Svit?kar Nikolai
- Swabe Jacqueline
- Sweet Katie
- Sy Eric
- Szakmany Tamas
- Szawarski Piotr
- Tai Charlotte
- Tait Jennifer
- Talia Nadine
- Tallott Mandy
- Tamm Tina
- Tamme Kadri
- Taqdees Huda
- Tarr Esther
- Tate Margaret
- Tatham Kate
- Tavares Silvia
- Taylor Holly
- Taylor Melanie
- Taylor Sian
- Tee Ameila
- Templeton Maie
- Teo Hoon
- Terrill Lenae
- The Stephanie
- Thedinga Karen
- Thomas Amy
- Thomas Ashly
- Thomas Emma
- Thomas Helen
- Thomas Matt
- Thomas Vicky
- Thompson Patricia
- Thompson Taylor
- Thomson Nicola
- Thrush Jessica
- Thurairatnam Saranya
- Tierney Carey
- Tinmouth Alan
- Tirot Patrice
- Tlayjeh Haytham
- Toffalo Sue
- Tolppa Timo
- Tomasi Enrico
- Tomlinson Helen
- Tong Steve
- Tong Steven
- Tony Kiran
- Totzke Juliane
- Touma Omar
- Towns Miriam
- Trapani Tony
- Trask Kara
- Traverse Eleanor
- Trickey Jemma
- Trim Fiona
- Trimmer Ken
- Triulzi Darrell
- Troeman Darren
- Trues Estefania
- Truman Nicholas
- Tsakiridou Kyriaki
- Tsang Jennifer
- Tsinaslanidis Georgios
- Tuckwell Caroline
- Tully Redmond
- Tully Riona
- Tung Raymond
- Tupper-Carey Daryl
- Turgeon Alexis F.
- Turki Salah
- Turner Anne M.
- Turner Elizabeth
- Turner Keri
- Turner-Bone Ian
- Turns Margaret
- TV Bharath
- Udayanga Ishara
- Uddin Ruzena
- Udy Andrew
- Ullmann Hannah
- Umrani Zulfiqar
- Unsworth Adam
- Uriel Alison
- Ustianowski Andrew
- Uyeki Tim
- Vaara Suvi
- Vaduganathan Muthiah
- Vahtera Annukka
- Vale Cassandra
- Valentine Eliza
- Vamplew Luke
- van Amerongen Roosmarijn
- van Bentum-Puijk Wilma
- van Bree Sjoerd
- van de Veerdonk Frank L.
- van den Berg Lettie
- van den Oever Huub
- van der Eng Hetty
- Van Der Heyden Kymbalee
- van der Kraan-Donker Annemarie
- van Gulik Laura
- van Haren Frank
- Van Hecke Jolien
- van Kimmenade Roland
- van Nieuwkoop Kees
- van Zanten Arthur
- van Zuylen Tamara
- Van?t Hoff William
- Vandewoestyne Sophie
- Vanjak Christian
- Vanmali Piyush
- van Opdorp Marjolein
- van Vonderen Marit
- Vargas Jr. Jesus
- Varghese Siby
- Vautier Sarah
- Vazquez-Grande Gloria
- Veenith Tonny
- Veillard Marion
- Venkatesh Bala
- Verlander Mark
- Vermassen Joris
- Vermeiren Daisy
- Vermont - van der Staaij Janine
- Verrier Nathalie
- Vertue Mark
- Verula Jerik
- Victor Saji
- Viehman Alex
- Vieillard-Baron Antoine
- Vignesh C
- Villot Solenne
- VilĂĄ Clara
- Vincent Rachel
- Virdee Satwinder
- Visentin Elisa
- Visser Yorik
- Vita Tina
- Vivier Dominique
- Vodovar Dominique
- Voicu Sebastian
- Voigt Ingo
- Voiriot Guillaume
- Volkov Lev
- Voza Gennaro
- Vuylsteke Alain
- Wada Asako
- Waddington Natalia
- Wahl Nadine
- Waite Alicia
- Walden Andrew
- Walker Gena
- Walker Rachel
- Walker Susan
- Walsh Joanne
- Walsh Tim
- Walsham James
- Walton Catherine
- Wang Shu
- Ward Geraldine
- Ward Kathryn
- Ward Luke
- Warnapura Loku
- Warnock Majella
- Watchorn Olivia
- Waters Abby
- Waterson Sharon
- Watkins Claire
- Watpool Irene
- Watters Malcolm
- Watts Angela
- Waugh Victoria
- Webb Steve A.
- Weber Lisa
- Webster Denise
- Weerasinghe Thanuja
- Weismann Dirk
- Weiss Daniel
- Weissman Alexandra
- Wells Alan
- Wells Colin
- Wells Karen
- Welters Ingeborg
- West Lauren
- Westlake Samantha
- Wetherill Bill
- Wetzold Richard
- Whileman Amanda
- Whitbread Jennifer
- White Alison
- White Hayden
- White Ian
- White Katie
- Whitehead Christina
- Whitehouse Tony
- Wibrow Bradley
- Wigbers Jeanette
- Wijewardena Gayathri
- Wilby Elizabeth
- Wilcox Elizabeth
- Wilcox Louise
- Wild Helen
- Wild Laura
- Wilding Laura
- Wiles Matt
- Wiley Daisy
- Wilhelmsen Elva
- Wilkinson Dean
- Willams Felicity
- Williams Alexandra
- Williams Angharad
- Williams Anna
- Williams Erin
- Williams Gemma
- Williams Hannah
- Williams Karen
- Williams Marie
- Williams Patricia
- Williams Penny
- Williams Tony
- Williams Virginie
- Williamson Dawn
- Williamson James D
- Willis Joanna
- Willson Jayne
- Wilson Anna
- Wilson Craig
- Wilson Jean
- Wilson Maggie
- Winters James
- Winters Lauren
- Wise Matt
- Wisniewski Mary
- Wittekamp Bastiaan
- Wittenberg Wendy
- Wnuk Chris
- Woelke Amy
- Wong Jenny
- Wong Onyee
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Woodward Robert
- Woolett Melissa
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Wright Chris
- Wright Kim
- Wunderley Renee
- Wyatt Rachel
- Wylie Katharine
- Xavier Kugan
- Yamagishi Yoshiaki
- Yamashita Chizuru
- Yang Yang
- Yarad Elizabeth
- Yates Bryan
- Yates David
- Yealy Donald
- Young Ian
- Young Meredith
- Young Paul
- Youngstein Taryn
- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zarychanski Ryan
- Zdanavidiene Ausra
- Zhao Xiao
- Zinzoni Vanessa
- Zitter Letizia
- Zouita Louisa
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 11/04/2023
- Field of study
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 nonâcritically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (nâ=â257), ARB (nâ=â248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; nâ=â10), or no RAS inhibitor (control; nâ=â264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ supportâfree days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ supportâfree days among critically ill patients was 10 (â1 to 16) in the ACE inhibitor group (nâ=â231), 8 (â1 to 17) in the ARB group (nâ=â217), and 12 (0 to 17) in the control group (nâ=â231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ supportâfree days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570