227 research outputs found

    Evaluation of Two Bone Anchored Appliances During En Masse Distalization of Maxillary Buccal Segment with Class II Patients; A Comparative Clinical Study

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    Objective: to assess quality of orthodontic tooth movement during distalization by two different skeletally anchored distalizing appliances. Patients and methods: the current study was applied on 22 orthodontic patients with class ΙΙ molar relationship. Patients were divided into two active groups; group Ι: include 11 patients treated by modified sagittal screw distalizer and group ΙΙ: include 11 patients treated by modified distal jet distalizer. Quality of distalization was assessed by the following measurements; first and second premolars root horizontal distance (mm), first and second molars root horizontal distance(mm), SNA, SNB, U1 to FH. Results: The highest change (%) in first molar root horizontal distance (mm) was recorded in group II with a decrease by -11.5 % in the left side and -11.4 % in the right side. Conclusion: Bone anchored Distal Jet and modified Sagittal screw distalizer provide an effective tool for treating mild to moderate class II malocclusion. But the modified distal jet produces high quality of distalization than the modified Sagittal screw distalizer

    Effect of genistein and oestradiol on the adrenal cortex of the ovariectomised adult female albino rats

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    Background: Genistein, a naturally occurring soy isoflavone, attracts interest as an effective and safe alternative to hormone replacement therapy for menopausal problems. The aim of the current study was to compare between the effect of genistein and oestradiol on the adrenal cortex of the ovariectomised adult female albino rats. Materials and methods: Twenty rats were used in the current study and divided into four groups, 5 rats in each group; group 1 (control non-ovariectomised), group 2 (ovariectomised), group 3 (ovariectomised + genistein) and group 4 (ovariectomised + oestradiol). The rats were sacrificed after 4 weeks. Both adrenal glands were removed for light microscope using haematoxylin and eosin stain, ultrastructural study and immunohistochemical examination using proliferating cell nuclear antigen, caspase-3, and oestrogen receptor-b. Results: Ovariectomised rats showed signs of degeneration in all zones of adrenal cortex. On the other hand, treatment with genistein showed restoration of the adrenal cortex with less proliferative effect than oestradiol. Conclusions: So, genistein can be used as effective therapy to decrease the symptoms of menopause without fear of cancer development

    Priprava derivata 4-aminofeniloctene kiseline s antimikrobnim djelovanjem

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    Condensation of 4-APAA with phthalic anhydride gave (dioxoisoindolin-2-yl)phenylacetic acid 1, which is employed as key intermediate in the synthesis of title compounds 2-8. The products have been characterized by analytical and spectral data (IR, 1H NMR, 13C NMR and mass spectra). Antimicrobial activities were also studied and some of these compounds gave promising results.Kondenzacijom 4-APAA s anhidridom ftalne kiseline dobivena je (dioksoizoindolin-2-il)feniloctena kiselina 1, koja je upotrebljena kao ključni intermedijer u sintezi spojeva 2-8. Produkti su karakterizirani analitičkim i spektroskopskim metodama (IR, 1H NMR, 13C NMR i MS). Neki od sintetiziranih spojeva ima značajno antimikrobno djelovanje

    Knowledge, attitude and practice of long acting reversible hormonal contraception (LARHC) among women in urban upper Egypt

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    Background: The current study aims to assess the knowledge, attitude and practice of long acting reversible hormonal contraception (LARHC) among women in urban upper Egypt.Methods: A cross sectional study which included 902 married women, in the reproductive age, attending the outpatient clinics (Gynecology and family planning) of: 1-Assiut University Maternity Hospital, 2- Sohag University Hospital, and 3-Gehina General Hospital (MOH hospital) with current or previous use of any method of LARHC methods. A Questionnaire file was designed to assay knowledge attitude and practice of clients towards contraceptive methods. All data collected from clients reviewed separately to assess knowledge, attitude and practice of women towards contraceptive methods.Results: The most popular contraceptive method is COCs followed by IUD then DMPA. 99% of studied sample heard with good description about different types of LARHC. 54.9% of studied sample most popular/famous LARHC DMPA, most sources of information on LARHC were, Hospital, Relative/friends and health workers. 94.24% of the studied sample were in favor to use of LARHC, 94.2% of them agree to take a space between births, about 55.4% of them were health child and 61% comfortable lifestyle benefit from birth spacing, 33% of studied sample were maternal health, 68% of them were think/prefer to use implants, 64.5% of them didn’t pregnant while breastfeeding. 11% of sample women never used any contraception before and most reasons for not using contraception are fear of side effects, desire for more children, irregular sexual relationship, and husband opposition. Only 16.6 % of studied sample used LARHC before and most of them used DMPA, however 3 women who used DMPA get pregnant while using it.Conclusions: There is a good level of knowledge between upper Egypt women about LARHC methods

    Design and implementation of 2.6 GHz Phase shift using microstrip technology for mobile broadband application

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    This paper evolves transmission line phase shifting to optimize system cost. The design of a 1 x 2 microstrip (patch) array antenna which has an operating frequency of 2.6 GHz. Substrate FR4 dielectric with dielectric constant of 4.4 and thickness of 1.6 mm is utilized in array design. The study is performed in four steps: Firstly, through simulating radiation pattern on CST by altering two independent parameters; Spacing between patches and differential length of transmission line from source to each patch antenna. Secondly, a fabrication has been done on a sample deferential length to two ports that simulating two microstrip (patch) antennas array. Thirdly, testing of radiation fields has been performed to verify the correlation between actual records and the simulated designed antenna phase shifting. Fourth and finally, A comparison of results has been included between this paper results and previous works in sake of showing the introduced effort added value

    Neurological Alterations in Type 1 Diabetes Mellitus Among Adolescents

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    BACKGROUND: Diabetes mellitus (DM) is a group of chronic disorders of metabolism characterised by high blood glucose levels. There is an increased prevalence of Type 1 DM in children and adolescents with its adverse complications especially microvascular ones (retinopathy, nephropathy and neuropathy) that might cause multiple organ damage. AIM: To study the relation between DM and neurological affection. METHODS: Fifty-nine children with type I DM, divided randomly into 2 groups, aged 8-18 years old of both sexes were enrolled in this cross-sectional study. All children were subjected to full history taking, physical, neurological and systemic examination. RESULTS: There was an affection of motor power in both upper limbs as well as lower limbs. Also, we found that there was an affection of the superficial peripheral sensation affecting both upper and lower limbs. CONCLUSION: Neurological assessment of children with diabetes mellitus type I should be a routine to early discover these manifestations which can have a deteriorating effect on the child’s health

    Glycated albumin and glycated albumin/ glycated haemoglobin ratio decrease with increasing BMI compared to Glycated haemoglobin in Type 2 diabetes patients

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    Abstract: Background: Obese T2DM patients are more prone to develop accelerated complications which burdens the global health systems with undue expenditure. Glycated haemoglobin (A1c) had been settled as a gold standard glycemic indicator though it's levels must be prudently interpreted in some patients. Glycatedalbumin (GA) as an alternative, intermediate glycemic indicator is gaining much attention. Aim: assessing the correlation of each of glycated albumin and glycated haemoglobin to body mass index (BMI) in T2DM patients Hypothesis: negative correlation existsbetween BMI & glycated albumin. Subjects and methods: Cross sectional study into which 62 participants-aged 25-60 years -who are T2DM on insulin were recruited at Suez Canal University hospital.None of them was smoker or known to be CLD or DKD patient, none was on regular statins, aspirin or metformin. All had normal CBC and albumin indices, they underwent thorough history taking & examination. anthropometric measurements namely body mass index (BMI) were taken.They were grouped into a non-obese group with BMI <25 Kg/m 2 & obese group whose BMI ≥25 Kg/m 2 , each with a sample size of 31 participants. FPG,PPPG, HbA1c, CBC, serum albumin, serum insulin and GA were analyzed.insulin resistance was measured by HOMA-IR. Results: GA was insignificantly lower in obese T2DM compared to non-obese (579.3 µmol/L vs 600.0 µmol/L,p-value = 0.631), while GA/HbA1c ratio was significantly low among obese compared to non-obese. (61.1 vs 66.8, p-value= 0.040). Also GA was insignificantly lower in obese with insulin resistance (615.0 ±177.5 µmol/L) than obese with no insulin resistance (550.0±148.2 µmol/L) and also lower than non-obese with insulin resistance (637.4±153.0 µmol/L).Similarly GA/HbA1c ratio was lower in obese with &without insulin resistance (mean 57.6 ±SD 12.8 & mean 64.1 ±SD 9.0 respectively) compared to GA/HbA1c ratio in non-obese with & without insulin resistance (mean 66.9 ±SD 11.0 & mean 66.7 ±SD 9.1 respectively). Conclusion: This study showed that care to be paid while interpreting GA levels in obese T2DM as GA and GA/HbA1c ratio are lower in this population. [Iman El -Sherif, Mohamed I. Shoeir, Mohamed M. Mohey El Din Awad, Amal Fathy and Seham Ahmed. Glycated albumin and glycated albumin/ glycated haemoglobin ratio decrease with increasing BMI compared to Glycated haemoglobin in Type 2 diabetes patients
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