316 research outputs found

    Efficacy of extended clomifene citrate regimen in comparison with gonadotropins in clomifene citrate-resistant women with polycystic ovary syndrome

    Get PDF
    Background: Gonadotropins are successful treatment for women with clomifene citrate (CC)-resistant polycystic ovary syndrome (PCOS). The aim of this study was to test the hypothesis that extended CC treatment may be an alternative to gonadotropins in the management of CC-resistant women with PCOS.Methods: A randomized controlled trial comprised 200 women with CC-resistant PCOS were allocated to two equal treatment groups. Patients in the CC group were given 100 mg of CC daily starting from the third day of menses for 10 days. Patients in the gonadotropins group were given follitropin-alfa according to step-up regimen starting on the 3rd day of menses. The primary outcome measure was the biochemical pregnancy rate [diagnosed by measuring serum β-human chorionic gonadotropin (β-HCG) 16-days after HCG injection] and clinical pregnancy rate (confirmed by vaginal ultrasound at six-weeks of amenorrhea). Secondary outcomes were: ovulation rate, endometrial thickness at HCG injection, and adverse drug events.Results: There were no statistically significant differences between the CC group and the gonadotropins group regarding biochemical pregnancy rates [21%, 24%; respectively, P=0.735; relative risk (RR)=0.88, 95% confidence interval (CI), 0.52-1.47], and clinical pregnancy rate [19%, 21%; respectively, P=0.86; RR=0.9, (95% CI, 0.52-1.58)]. No significant difference was displayed regarding ovulation rate, endometrial thickness at HCG, and adverse drug events.Conclusions: The extended CC regimen appears to constitute a good alternative to gonadotropins therapy in patients with CC-resistant PCOS. Further multi-center studies are needed to confirm our results and to provide more powerful evidence

    Le Conte du moucharabieh

    Get PDF
    Écrit au Caire en 1942. Révisé et réécrit en 1984, Le Caire. Lieu de l’histoire : Le Caire, quartier de la Citadelle et quartier al-Nahasin. Époque de l’histoire : Le xxe siècle, ainsi que le xive siècle. Les personnages de l’histoire à l’époque contemporaine 1. Khalid : Un jeune homme de 35 ans, imprégné tout à la fois de culture orientale et occidentale. Animé d’un sentiment nationaliste, il désire voir perdurer le parfum d’éternité de la vie orientale, sans qu’il n’entrave le cours de la v..

    Primary Science Teachers’ Perceptions towards STEM Education in Public Schools in Qatar

    Get PDF
    Understanding teachers' perceptions of STEM education is crucial to ensure the quality of teaching and learning provided for the students in the classrooms. This study aimed at investigating science teachers’ perceptions towards STEM education in primary public schools in the State of Qatar in terms of: teachers' knowledge, STEM teaching requirements, impact on students' outcomes. This study followed a sequential explanatory mixed-method approach. Quantitative data was collected by surveying (148) science teachers, while qualitative data was obtained using four focus groups. Results indicated that teachers have relatively high perceptions towards STEM education. However, the findings highlighted the need to increase teachers’ understanding and knowledge of STEM disciplines and their approaches to integration. Keywords: STEM education, perceptions, science teachers. DOI: 10.7176/JEP/13-24-04 Publication date:August 31st 202

    Podcasting as an Effective Pedagogy for Teaching Chemistry During the COVID-19 Pandemic and Beyond

    Get PDF
    The COVID-19 pandemic has forced all educational institutions worldwide to switch their active routine to ONLINE. With students attending classes virtually, a number of problems arose including the absence of social interaction and the imposed difficulty of digesting the materials of different courses, especially for those with a scientific background. General chemistry (GC), as an introductory course, is usually registered by students from different backgrounds, including Science, Engineering, and Agriculture. At the United Arab Emirates University, the second level of GC (GCII) is more focused on problem-solving as related to various topics. With the absence of face-to-face experience because of the COVID-19 circumstances, students’ understanding of the chemical concepts and implementing that in problem-solving has become a challenge. The current work investigates the effect of using professionally-made podcasts of GCII on the extent of understanding of students registered for this course during the period of 2020-2020 over a course of four semesters. The results of surveying the usage and feedback of students engaged in this experiment are outlined. Conclusively, this pedagogy is fully supported by most of the students who regard it as a suitable alternative to face-to-face settings

    Color Portion of Solar Radiation in the Partial Annular Solar Eclipse, October 3rd, 2005, at Helwan, Egypt

    Get PDF
    Measurements were made of various solar radiation components, global, direct and diffuse and their fractions during the partial annular solar eclipse on October 3rd, 2005 at Helwan, Egypt (Lat. 29.866â—¦ N and Long. 31.20â—¦ E), and an analysis has been made. The duration of the solar eclipse was 3 h 17 min, and the maximum magnitude of the eclipse in this region was 0.65. The optical depth of the direct component and the relative humidity decreased, while both the transparency and the air temperature increased towards the maximum eclipse. The general trends of the global components are decreasing optical depth and increasing transparency between the first contact and the last contact. The prevailing color during the eclipse duration was diffused infrared (77 % of the total diffuse radiation level)

    Gravity observations at Sinai Peninsula and its geophysical and geodetic applications

    Get PDF
    AbstractSouth Sinai is an interesting region from both tectonic and seismological settings. Tectonically, Sinai Peninsula is strongly dominated by its active boundaries due to its location at the triple junction among the Gulf of Suez rift, the Aqaba–Levant transform fault and the Red Sea Rift. Moreover, reported seismological activities along the three tectonic boundaries indicate its continuous activities.It is thus of great interest to delineate the subsurface geological structure responsible of its tectonic settings and its relation to the seismological activity. Therefore, terrestrial gravity observation has been carried out to figure out the sub-surface structure representing its tectonic settings.On the other hand, the location of Sinai Peninsula between Gulf of Suez, Gulf of Aqepa and Red Sea has made the satellite altimetry data an optimum tool to determine the Gravity sources on the marine regions bounding the Sinai region. Finally, temporal gravity variation of the GRACE satellite mission, launched in 2003 gives the opportunity to monitor its temporal gravity variation on regional scale. Temporal gravity variation from GRACE demonstrates any possible mass redistribution along the pounding tectonic settings and its relation to seismicity.Observed gravity map shows significant gravity anomalies attributed to tectonic and seismicity. Satellite altimetry and gravity data are considered to be a valuable source of data to determine the offshore subsurface structure. Temporal gravity variations from GRACE shows important zones of mass redistribution attributed to its new tectonics and its relation to the seismological activities. Integrating all available data sheds more light on the geodynamic behavior of the selected region and its relation to the seismic activities

    Early Cerebrovascular Silent Changes in Long-Standing End-Stage Renal Disease Patients on Hemodialysis Value of Adding Advanced Unenhanced MRI Sequences to Imaging Protocols

    Get PDF
    Background: End-Stage Renal Disease (ESRD) patients on hemodialysis suffered from many central and peripheral neurological insults. Aim of the work:This study aimed to assess the value of using MRA, MRV, and SWAN sequences in early visualization of the silent cerebrovascular complications in those patients. Patients and Methods: Our study was conducted on forty-five patients with well-documented ESRD on regular hemodialysis for more than 5 years with no neurological manifestation, all undergone unenhanced MRI, DWI with ADC and measuring the ADC value, SWAN, MRA, and MRV. Results: we found that 11% of cases have acute infarction at the basal ganglia region. 36.7% of patients are diagnosed with intracerebral hemorrhage, only 26.7% of them are seen by the conventional MRI, and 16.7% of cases showed microbleeds on SWAN with normal conventional MRI. The sensitivity and specificity of SWAN with ADC value to detect brain hemorrhage are 100% and 88.8% respectively. Conclusion: Visualization of cerebrovascular complications such as infarction, hemorrhage, atherosclerosis, and arterial and venous occlusion using DWI with ADC, MRA, MRV, and SWAN and is very useful in early management and better prognosis of ESRD patients even with silent complications that don’t give up symptoms with high sensitivity and specificity of SWAN in early detection of hemorrhage and microbleeds
    • …
    corecore