18 research outputs found

    Weed Control in Annual Strawberries Grown with Plastic Mulch: Efficacy, Phytotoxicity, and Soil Persistence Studies

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    Cool soil temperatures in Alaska are a limiting factor for many crops. Clear plastic mulch has been shown to increase soil temperatures, and use of this mulch has allowed the production of many warm season crops farther north than they could otherwise be grown. Clear plastic mulch and row covers are used in interior Alaska to promote early growth and increase yields of strawberries

    Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren’s syndrome

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    Sjögren’s syndrome is a common autoimmune disease (~0.7% of European Americans) typically presenting as keratoconjunctivitis sicca and xerostomia. In addition to strong association within the HLA region at 6p21 (Pmeta=7.65×10−114), we establish associations with IRF5-TNPO3 (Pmeta=2.73×10−19), STAT4 (Pmeta=6.80×10−15), IL12A (Pmeta =1.17×10−10), FAM167A-BLK (Pmeta=4.97×10−10), DDX6-CXCR5 (Pmeta=1.10×10−8), and TNIP1 (Pmeta=3.30×10−8). Suggestive associations with Pmeta<5×10−5 were observed with 29 regions including TNFAIP3, PTTG1, PRDM1, DGKQ, FCGR2A, IRAK1BP1, ITSN2, and PHIP amongst others. These results highlight the importance of genes involved in both innate and adaptive immunity in Sjögren’s syndrome

    Exploring UK medical school differences: the MedDifs study of selection, teaching, student and F1 perceptions, postgraduate outcomes and fitness to practise.

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    BACKGROUND: Medical schools differ, particularly in their teaching, but it is unclear whether such differences matter, although influential claims are often made. The Medical School Differences (MedDifs) study brings together a wide range of measures of UK medical schools, including postgraduate performance, fitness to practise issues, specialty choice, preparedness, satisfaction, teaching styles, entry criteria and institutional factors. METHOD: Aggregated data were collected for 50 measures across 29 UK medical schools. Data include institutional history (e.g. rate of production of hospital and GP specialists in the past), curricular influences (e.g. PBL schools, spend per student, staff-student ratio), selection measures (e.g. entry grades), teaching and assessment (e.g. traditional vs PBL, specialty teaching, self-regulated learning), student satisfaction, Foundation selection scores, Foundation satisfaction, postgraduate examination performance and fitness to practise (postgraduate progression, GMC sanctions). Six specialties (General Practice, Psychiatry, Anaesthetics, Obstetrics and Gynaecology, Internal Medicine, Surgery) were examined in more detail. RESULTS: Medical school differences are stable across time (median alpha = 0.835). The 50 measures were highly correlated, 395 (32.2%) of 1225 correlations being significant with p < 0.05, and 201 (16.4%) reached a Tukey-adjusted criterion of p < 0.0025. Problem-based learning (PBL) schools differ on many measures, including lower performance on postgraduate assessments. While these are in part explained by lower entry grades, a surprising finding is that schools such as PBL schools which reported greater student satisfaction with feedback also showed lower performance at postgraduate examinations. More medical school teaching of psychiatry, surgery and anaesthetics did not result in more specialist trainees. Schools that taught more general practice did have more graduates entering GP training, but those graduates performed less well in MRCGP examinations, the negative correlation resulting from numbers of GP trainees and exam outcomes being affected both by non-traditional teaching and by greater historical production of GPs. Postgraduate exam outcomes were also higher in schools with more self-regulated learning, but lower in larger medical schools. A path model for 29 measures found a complex causal nexus, most measures causing or being caused by other measures. Postgraduate exam performance was influenced by earlier attainment, at entry to Foundation and entry to medical school (the so-called academic backbone), and by self-regulated learning. Foundation measures of satisfaction, including preparedness, had no subsequent influence on outcomes. Fitness to practise issues were more frequent in schools producing more male graduates and more GPs. CONCLUSIONS: Medical schools differ in large numbers of ways that are causally interconnected. Differences between schools in postgraduate examination performance, training problems and GMC sanctions have important implications for the quality of patient care and patient safety

    The Analysis of Teaching of Medical Schools (AToMS) survey: an analysis of 47,258 timetabled teaching events in 25 UK medical schools relating to timing, duration, teaching formats, teaching content, and problem-based learning.

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    BACKGROUND: What subjects UK medical schools teach, what ways they teach subjects, and how much they teach those subjects is unclear. Whether teaching differences matter is a separate, important question. This study provides a detailed picture of timetabled undergraduate teaching activity at 25 UK medical schools, particularly in relation to problem-based learning (PBL). METHOD: The Analysis of Teaching of Medical Schools (AToMS) survey used detailed timetables provided by 25 schools with standard 5-year courses. Timetabled teaching events were coded in terms of course year, duration, teaching format, and teaching content. Ten schools used PBL. Teaching times from timetables were validated against two other studies that had assessed GP teaching and lecture, seminar, and tutorial times. RESULTS: A total of 47,258 timetabled teaching events in the academic year 2014/2015 were analysed, including SSCs (student-selected components) and elective studies. A typical UK medical student receives 3960 timetabled hours of teaching during their 5-year course. There was a clear difference between the initial 2 years which mostly contained basic medical science content and the later 3 years which mostly consisted of clinical teaching, although some clinical teaching occurs in the first 2 years. Medical schools differed in duration, format, and content of teaching. Two main factors underlay most of the variation between schools, Traditional vs PBL teaching and Structured vs Unstructured teaching. A curriculum map comparing medical schools was constructed using those factors. PBL schools differed on a number of measures, having more PBL teaching time, fewer lectures, more GP teaching, less surgery, less formal teaching of basic science, and more sessions with unspecified content. DISCUSSION: UK medical schools differ in both format and content of teaching. PBL and non-PBL schools clearly differ, albeit with substantial variation within groups, and overlap in the middle. The important question of whether differences in teaching matter in terms of outcomes is analysed in a companion study (MedDifs) which examines how teaching differences relate to university infrastructure, entry requirements, student perceptions, and outcomes in Foundation Programme and postgraduate training

    Untold stories: an interpretive study of older women sexually abused as children

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    Thesis (Ph. D.)--University of Washington, 1996Although nearly five million women over age 55 are estimated to have been sexually abused as children, little is known of their experience. This interpretive study attempts to understand the effects of child sexual abuse for older women and their ways of coping with it. Audio taped life stories were collected from 12 women, ages 57 to 75. Tapes were transcribed and narrative analysis was used to examine the effects of the abuse and women's ways of coping within the lives of three individual women. Inductive analytic coding was used to examine those issues across the total sample.Results from this study indicate that older women experienced the same effects from the abuse as younger women, including negative feelings about the self, guilt, self-blame, sexual problems, and lost opportunities. Gender roles for these older women complicated the abuse, negatively impacting self-esteem, self-development, and feelings of justice. The experience of sexual abuse in childhood resonated across women's lives, complicating developmental tasks of aging such as widowhood, changing sexual relations, and retirement. Many of these women endured the abuse as children and the effects of it as adults. They were acquiescent in relationships and silent about their feelings and thoughts. Several resolved the effects of the abuse and the limitations of gender roles by gaining their voice, making choices and overcoming the past. All of the women exhibited remarkable resourcefulness and some degree of resiliency. Self-in-relation theory is proposed as a theoretical framework to explain women's coping strategies.The organizational structure of the life stories and individual narrative structures reflect how three women coped with the abuse. They told stories of endurance, gaining a voice, and transcendence. Narrative analysis revealed the impact of the abuse throughout their lives. It facilitated an understanding of what the abuse meant to each woman and how she coped with it. How women told their stories was part of their story

    Democracy : A Project by Group Material

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    Identifying four areas of crisis in democracy in the U.S.A. (education, electoral politics, cultural participation and AIDS), Group Material employs exhibitions comprised of over 160 artists' works and the collaborative processes of roundtable discussions and townmeetings to analyse these issues while deconstructing the exclusiveness of cultural practice. Includes documentation of the project and supplementary essays and interviews
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