Effect of Parents’ Involvement Interventions in Speech Language Delay among Late Talking Toddlers in Egypt: A Quasi-Experimental Study

Background: Speech language delay is a common developmental problem among Egyptian children. There is paucity of reliable data on parent involvement interventions in speech language problems and of communication disorders in Egypt. Objective: We evaluated the effect of parent involvement in language development intervention programmes on a population of late talking toddlers recruited from local kindergarten schools in Alexandria, Egypt, using interaction-promoting strategies which encourage children to take turns in a conversation, ask questions and wait for a response. Methods: Seventy-nine mother-child pairs were randomly assigned into an experimental group where a validated Language Development Survey (LDS) was administered while study mothers assigned to control arm had routine care according to kindergartens policy in Egypt. Pre-and post-intervention assessments were conducted on all domains of the tool. Results: Approximately one third (30.9%) of the study children in the experimental group had severe language delay pre-intervention and this decreased to 16.2% of children post-intervention. On the other hand, less than one quarter (18.2%) of the study children in the control group had severe language delay pre-intervention, this increased to about half (54.5%) of children post-intervention (p=<0.043).This showed that significant expressive language gains can be made by pre-school language-delayed children, through group parental-based language intervention. Conclusion: Findings of this study suggest that parent involvement had positive outcomes in terms of language development in their late-talking toddlers. The study supports the concept of parent involvement as a viable model of language intervention for promoting short-term developmental progress in late-talking toddlers

Acute leukemia of ambiguous lineage with trisomy 4 as the sole cytogenetic abnormality: A case report and literature review

AbstractWe describe a patient with acute leukemia of ambiguous lineage who had trisomy 4 as the sole cytogenetic abnormality. Clinical, pathological, immunophenotypic and molecular features are presented and compared with the previous 4 published cases. Over expression of c-kit, which is localized to chromosome 4, was documented on the leukemic blasts. Prognosis seems to be poor. Treatment with acute lymphoblastic leukemia like regimens seems to be superior compared to acute myeloid leukemia like regimens and allogeneic stem cell transplant is recommended after achieving remission

Technical and Economical Investigation of Renewable Energy Sources for Supplying Offshore Oil production Facilities at Gulf of Suez Area

The Gulf of Suez is highly susceptible to economic and energy security due to the heavy need for imported fossil fuels. The energy produced from fossil fuels causes serious environmental pollution. So, it is important to find other clean sources of energy for stabilizing the released amount of carbon dioxide. Gulf of Suez has the potential to develop clean Solar Photovoltaic (PV) and wind systems to improve economic and environmental performance. This paper proposes a combination of floating solar panels (FSP) and offshore wind turbines to solve the main critical issues, such as the land area required for a large number of cells and the space required for wind turbines. In addition to their good economical and environmental benefits. A simplified model is provided to investigate the replacement of traditional generating units (Diesel and Gas operated) supplying offshore oil production field facilities at the Gulf of Suez area with a mix of renewable resources. The load flow analysis is carried out for the model and the cost is calculated and compared for four schemas, the traditional generating, Wind-Gas, PV-Gas, and PV-Wind-Gas hybrid system. From the techno-economic analysis and comparing environmental benefits, floating solar systems and offshore wind turbines can provide a good solution to the existing problems of energy needs with environmental impacts considered

Sinai and Norfa chicken diversity revealed by microsatellite markers

The present study aimed to outline the population differentiation of Sinai and Norfa chicken, native to Egypt, with microsatellite markers. Twenty microsatellite loci recommended by the Food and Agriculture Organization (FAO) were used. Fifty eight birds were sampled (29 for each strain: 12 males + 17 females). Data were collected and genetic diversity indicators were assessed utilizing the approaches implemented in FSTAT, Cervus 3.0.7 and GenAlEx 6.5 software programmes. A total number of 182 alleles were detected with an average value of 9.1 allele per locus. The expected heterozygosity was 6.625 and 6.343 in Norfa and Sinai chickens, respectively. Norfa chickens produced 15 private alleles, while there were 9 unique alleles detected in Sinai chickens (13.18% private alleles as a percentage of the total observed number of alleles). Fixation indices’ (FST, FIS, and FIT) values were 0.060, 0.410 and 0.438, respectively, across all 20 loci investigated. Results indicated that the studied populations were genetically differentiated. Consequently, they have high breeding potential. Efforts should be made to incorporate the other local chicken strains as unique genetic resources into conservation programmes. This should begin with proper management of these flocks to ensure the maintenance of their genetic diversity over time by avoiding inbreeding. Such information is likely to have a profound effect on the success of genetic improvement and completes information from phenotypes and biometric measurements of the domestic chickens in Egypt.Keywords: Egyptian, genetic diversity, local chicken, microsatellit

Epidural anaesthesia and myomectomy-associated blood loss: — a prospective randomised controlled study

Objectives: The management of anaesthesia for patients with large myomas is particularly important due to disruption of hemodynamic as a result of massive haemorrhage, the prolonged duration of surgery and requirement for additional interventions. This study evaluated the effect of anaesthetic technique on blood loss in patients undergoing myomectomy due to large fibroid uterus. Material and methods: A total of 156 patients that underwent myomectomy were randomized into two equal groups according to the type of anaesthesia: Epidural anaesthesia group and General anaesthesia group. The volume of blood loss and blood products transfusion was reviewed for each patient. Results: The intraoperative blood loss and need for blood transfusion were significantly higher in general anaesthesia group (p &lt; 0.001). The mean hematocrit change was 2.5 ± 1.5 vs 3.7 ± 2.9 % (p = 0.001) for both groups. Conclusions: In the myomectomy planning of women with a large fibroid uterus, the team of gynecologists and anaesthesiologists should take care to choose the most optimal technique for anaesthesia

Test of Lorentz Violation with Astrophysical Neutrino Flavor in IceCube

4 pages, 1 figure, presented at the Eighth Meeting on CPT and Lorentz Symmetry, Bloomington, Indiana, May 12-16, 20194 pages, 1 figure, presented at the Eighth Meeting on CPT and Lorentz Symmetry, Bloomington, Indiana, May 12-16, 20194 pages, 1 figure, presented at the Eighth Meeting on CPT and Lorentz Symmetry, Bloomington, Indiana, May 12-16, 2019Astrophysical high-energy neutrinos observed by IceCube are sensitive to small effects in a vacuum such as those motivated from quantum gravity theories. Here, we discuss the potential sensitivity of Lorentz violation from the diffuse astrophysical neutrino data in IceCube. The estimated sensitivity reaches the Planck scale physics motivated region, providing IceCube with real discovery potential of Lorentz violation

Influence of short- and long-term administration of Melengestrol acetate on estrus activity and reproductive performance of nulliparous Barki ewes

In Egypt, research focusing on estrous synchronization in small ruminants based on Melengestrol acetate (MGA) supplementation, particularly in nulliparous ewes, is still lacking. The present work aimed to evaluate effect of long-term and short-term administration of melengestrol acetate (MGA) treatments on estrus synchronization and reproductive performance of nulliparous Barki Ewes. This study was performed in Siwa Oasis Research Station (Tegzerty Experimental Farm for animal production), belonged to Desert Research Center, Egypt. Forty five nulliparous Barki ewes with age ranging from 15.5 to 16.5 months, and 38 ± 0.23 kg average live body weight were assigned to one of three groups: (1) control (C, n = 15); (2) long-term treatment with MGA (n = 15, 0.22 mg/ewe/d for 14 days) and (3) short-term treatment with MGA (n = 15, 0.22 mg/ewe/d for 7 days). At the end of MGA treatment (14 or 7 d) all treated ewes were injected by 600 IU PMSG intramuscularly. The results showed that, ewes treated with MGA exhibited highest (

A comprehensive exploration on different machine learning techniques for state of charge estimation of EV battery

The State of Charge (SoC) is a measurement of the amount of energy available in a battery at a specific interval of time, mostly expressed as percentage. Proportional relationships between the electromotive force of a battery, current, terminal voltage and temperature determine the SoC. There can be a considerable error in the calculations due to a sharp drop of the terminal voltage at the end of discharge. This research has explored how important SoC is, as a factor in Battery Management Systems. The work focuses on using machine learning techniques to obtain an accurate and reliable status of battery charge, this includes Random Forest, Decision Tree, Gradient Boosting, Support Vector Regression, Polynomial Regression and Multilayer Perceptron. In this paper, these techniques are tested and compared with two real world captured datasets of Lithium-ion batteries which includes LG Battery and Unibo Powertools Battery. For supporting this study, statistical methods like K-fold cross validation and Grid Search cross validation techniques are used to estimate the skill of machine learning models. After implementing these techniques, it is found that Random Forest model returns the best Accuracy and Decision Tree returns the least Mean Absolute Error.</p

Сравнение показателей соотношений тромбоциты / лимфоциты и нейтрофилы / лимфоциты в качестве предикторов исхода COVID-19

Clinical presentation is an undependable prognostic indicator of COVID-19 (COronaVIrus Disease 2019). So, a more objective predictor is needed to precisely evaluate and classify the prognosis. Immune dysregulation to lymphocytes, mainly T-lymphocytes, have been noticed between COVID-19 patients. The aim. This study was planned to determine the role of platelet-to-lymphocyte count ratio and neutrophil-to-lymphocyte ratio in assessment of COVID-19 prognosis. Methods. 70 hospitalized patients with confirmed COVID-19 were included in this study. All included patients underwent a consistent clinical, radiological and blood examination. Laboratory analysis was made by means of a commercially accessible kit. Blood cells ratios were computed by dividing their absolute counts. Results. Non-significant association was found between laboratory data and COVID-19 clinical severity. A significant association between CT classification and platelet-to-lymphocyte count ratio (higher value in L type; p = 0.001) was detected. Platelet-to-lymphocyte count ratio was significantly higher among intubated cases. However, Non-significant association was found between neutrophil-to-lymphocyte ratio and need of endotracheal intubation. Conclusion. Routine blood values are abnormal in patients with COVID-19. Platelet-to-lymphocyte count ratio ratios could be used as more meaningful biomarker than other values in predicting the prognosis of COVID-19. LMR helpful in COVID-19 severity.Клиническая картина является ненадежным показателем прогноза исхода новой коронавирусной инфекции (НКИ), поэтому для точной оценки и классификации прогноза необходим более объективный прогнозирующий фактор. У пациентов, перенесших НКИ, отмечается нарушение регуляции иммунного ответа со стороны лимфоцитов, в основном Т-лимфоцитов. Целью исследования явилось определение роли показателей соотношений тромбоциты / лимфоциты и нейтрофилы / лимфоциты при оценке прогноза COVID-19. Материалы и методы. В исследование были включены госпитализированные пациенты (n = 70) с подтвержденным COVID-19 (COronaVIrus Disease 2019). У всех пациентов проводились последовательное клиническое и рентгенологическое обследование и анализ крови. Лабораторные анализы выполнялись с помощью коммерческого набора. Соотношения показателей клеток крови рассчитывались путем деления их абсолютного количества. Результаты. Обнаружена незначимая связь между лабораторными показателями и степенью тяжести COVID-19. Выявлена значимая связь между степенью поражения легких по данным компьютерной томографии и показателем соотношения тромбоциты / лимфоциты (более высокое значение для L-типа; p = 0,001). У интубированных пациентов соотношение показателя тромбоциты / лимфоциты было значимо выше. Однако обнаружена незначимая связь между показателем соотношения нейтрофилы / лимфоциты и необходимостью интубации трахеи. Заключение. У пациентов с COVID-19 наблюдаются отклонения показателей рутинных анализов крови. Показатель соотношения тромбоциты / лимфоциты может служить биомаркером при прогнозировании течения COVID-19, а показатель соотношения лимфоциты / моноциты полезен при прогнозировании степени тяжести COVID-19