673 research outputs found

    ESTIMATING RETURNS FROM PAST INVESTMENTS INTO BEEF CATTLE GENETICS RD&E IN AUSTRALIA

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    This study aimed at estimating the costs and benefits of all beef cattle genetic improvement activity, across Australia, over the period 1970 to the present. The total cumulative Present Value (PV) of investments by industry, government and other agencies into selection, crossbreeding and grading up since 1963, and of imported genetics, was estimated to be 340m(in340m (in 2001 at a 7% discount rate). Using a suite of genetic evaluation models, farming systems models and an industry-level model, the cumulative PV of industry returns were estimated. Within-breed selection generated 944m;crossbreedinginsouthernAustralia944m; crossbreeding in southern Australia 255m; changing breed composition in southern Australia 62m;andchangingbreedcompositioninnorthernAustralia62m; and changing breed composition in northern Australia 8.1bn. The benefit/cost ratio for this investment was 28:1 over the last 30 years.Livestock Production/Industries, Research and Development/Tech Change/Emerging Technologies,

    Field measurements of bare soil evaporation and crop transpiration, and transpiration efficiency, for rainfed grain crops in Australia - A review

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    Available online 30 April 2018Australian agriculture is dominated by rainfed cropping in environments where evaporative demand greatly exceeds annual rainfall. In this paper we review field measurements of crop transpiration and bare soil evaporation under rainfed grain crops, and crop transpiration efficiencies. Crop transpiration is typically calculated from the difference between evapotranspiration and bare soil evaporation, however, while the former is readily measured, the latter is difficult to obtain. For wheat we found only 19 studies which measured the critical water balance parameters of bare soil evaporation and crop transpiration in Australia, and very many fewer for other crops. From the studies reported for wheat, on average 38% of evapotranspiration was lost to direct soil evaporation. Data for other crops are insufficient to ascertain whether they are similar or different to wheat in terms of the relative contributions of Es and T to the water balance. Although it may have occurred in practice, we can find no field measurements of the crop water balance to demonstrate an increase in crop transpiration at the expense of bare soil evaporation as a function of improvements in agronomic practices in recent decades. Although it is thought that crop transpiration efficiencies are primarily a function of vapour pressure deficit, transpiration efficiencies reported in the literature vary considerably within crops, even after accounting for vapour pressure deficit. We conclude that more reliable estimates of crop transpiration efficiency would be highly valuable for calculating seasonal transpiration of field grown crops from shoot biomass measurement, and provide an fruitful avenue for exploring water use efficiency of grain crops.Murray Unkovich, Jeff Baldock, Ryan Farquharso

    Impact of co‐morbid personality disorder on quality of inpatient mental health services for people with anxiety and depression

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    Introduction Concerns have been raised about the quality of inpatient care received by patients with a diagnosis of personality disorder. Objectives The aim of this study was to examine the quality of care received by inpatients with an anxiety or depressive disorder, comparing subgroups with or without a co‐morbid personality disorder. Method We used a retrospective case‐note review of 3 795 patients admitted to inpatient psychiatric wards in England, utilizing data from the National Clinical Audit of Anxiety and Depression. Data were gathered on all acute admissions with an anxiety or depressive disorder over a 6‐month period, for a number of measures reflecting quality of care derived from national standards. Association of coexisting personality disorder with quality of care was investigated using multivariable regression analyses. Results Four hundred sixteen (11.0%) of the patients had a co‐co‐morbid diagnosis of personality disorder. Patients with personality disorder were less likely to have been asked about prior responses to treatment in their initial assessment (odds ratio (OR) = 0.67, 95% confidence interval (CI) 0.50 to 0.89, p = 0.007). They were less likely to receive adequate notice in advance of their discharge (OR = 0.87, 95% CI 0.65 to 0.98, p = 0.046). They were more likely to be prescribed medication at the point of discharge (OR = 1.52, 95% CI 1.02 to 2.09, p = 0.012) and less likely to have been provided with information about the medicines they were taking (OR = 0.86, 95% CI 0.69 to 0.94, p = 0.048). In addition, the carers of patients with co‐morbid personality disorder were less likely to have been provided with information about available support services (OR = 0.73, 95% CI 0.51 to 0.93, p = 0.045). Conclusion We found evidence of poorer quality of care for patients with co‐morbid personality disorder who were admitted to psychiatric hospital for treatment of anxiety or depressive disorders, highlighting the need for improved clinical care in this patient group

    β-Glucan is a major growth substrate for human gut bacteria related to Coprococcus eutactus

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    A clone encoding carboxymethyl cellulase activity was isolated during functional screening of a human gut metagenomic library using Lactococcus lactis MG1363 as heterologous host. The insert carried a glycoside hydrolase family 9 (GH9) catalytic domain with sequence similarity to a gene from Coprococcus eutactus ART55/1. Genome surveys indicated a limited distribution of GH9 domains among dominant human colonic anaerobes. Genomes of C. eutactus-related strains harboured two GH9-encoding and four GH5-encoding genes, but the strains did not appear to degrade cellulose. Instead, they grew well on β-glucans and one of the strains also grew on galactomannan, galactan, glucomannan and starch. Coprococcus comes and Coprococcus catus strains did not harbour GH9 genes and were not able to grow on β-glucans. Gene expression and proteomic analysis of C. eutactus ART55/1 grown on cellobiose, β-glucan and lichenan revealed similar changes in expression in comparison to glucose. On β-glucan and lichenan only, one of the four GH5 genes was strongly upregulated. Growth on glucomannan led to a transcriptional response of many genes, in particular a strong upregulation of glycoside hydrolases involved in mannan degradation. Thus, β-glucans are a major growth substrate for species related to C. eutactus, with glucomannan and galactans alternative substrates for some strains

    Re-thinking soil carbon modelling: a stochastic approach to quantify uncertainties

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    The benefits of sequestering carbon are many, including improved crop productivity, reductions in greenhouse gases, and financial gains through the sale of carbon credits. Achieving better understanding of the sequestration process has motivated many deterministic models of soil carbon dynamics, but none of these models addresses uncertainty in a comprehensive manner. Uncertainty arises in many ways - around the model inputs, parameters, and dynamics, and subsequently model predictions. In this paper, these uncertainties are addressed in concert by incorporating a physical-statistical model for carbon dynamics within a Bayesian hierarchical modelling framework. This comprehensive approach to accounting for uncertainty in soil carbon modelling has not been attempted previously. This paper demonstrates proof-of-concept based on a one-pool model and identifies requirements for extension to multi-pool carbon modelling. Our model is based on the soil carbon dynamics in Tarlee, South Australia. We specify the model conditionally through its parameters, soil carbon input and decay processes, and observations of those processes. We use a particle marginal Metropolis-Hastings approach specified using the LibBi modelling language. We highlight how samples from the posterior distribution can be used to summarise our knowledge about model parameters, to estimate the probabilities of sequestering carbon, and to forecast changes in carbon stocks under crop rotations not represented explicitly in the original field trials

    Budget Processes: Theory and Experimental Evidence

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    This paper studies budget processes, both theoretically and experimentally. We compare the outcomes of bottom-up and top-down budget processes. It is often presumed that a top-down budget process leads to a smaller overall budget than a bottom-up budget process. Ferejohn and Krehbiel (1987) showed theoretically that this need not be the case. We test experimentally the theoretical predictions of their work. The evidence from these experiments lends strong support to their theory, both at the aggregate and the individual subject level

    Quality of English inpatient mental health services for people with anxiety or depressive disorders: Findings and recommendations from the core audit of the National Clinical Audit of Anxiety and Depression

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    Background Clinical audit is a sustained cyclical quality improvement process seeking to improve patient care and outcomes by evaluating services against explicit standards and implementing necessary changes. National audits aim to improve population-level clinical care by identifying unwarranted variations and making recommendations for clinicians, managers and service commissioners. The National Clinical Audit of Anxiety and Depression aimed to improve clinical care for people admitted to English hospitals for treatment of anxiety and depression, to provide comparative data on quality of care, and to support local quality improvement initiatives by identifying and sharing examples of best practice. Procedures Thirteen standards were developed based on NICE guidelines, literature review and feedback from a steering committee and reference group of service users and carers. All providers of NHS inpatient mental health services in England submitted details of between 20 and 100 service users/patients admitted between April 2017 and September 2018. To ascertain data reliability, participating services re-audited 5 sets of case-notes with a second auditor, and the coordinating team checked 10 randomly-selected sets of case-notes from 3 services, also selected at random. The reference group and steering committee identified key findings and developed a series of recommendations, which were discussed in regional quality improvement workshops and on-line webinars. Findings Data from 3795 case notes were analysed. A sizeable proportion of records indicated that at least one important aspect of initial assessment was not documented. Many service users/patients who could have benefited from an intervention targeted at optimising physical health did not receive it. Only a minority (39%) were referred for psychological therapy. Use of outcome measures varied considerably but no single outcome measure was being used routinely. Most individuals had a care plan recorded in the notes, but a review date was documented in only two-thirds, and almost half of individuals had not received a copy. Conclusions There was considerable variation between English mental health services across many variables, and much scope for improvement. Clinicians should ensure that care plans are developed collaboratively with service users/patients and identified carers should be provided with information about support services. Health services should investigate the reasons for low referral rates for psychological therapies. Clinicians should ensure all service users have jointly developed crisis plans in place at discharge. Service managers should agree outcome measures to evaluate the treatment provided and clinicians should use these measures at initial assessment and review appointments. The implementation of such changes provides an opportunity for collaborative research into mental health service delivery and quality
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