Effect of Tocopherol Extraction of Lepidium Sativum Seeds in Sperm Parameters of White Male Rabbits

The objective of this research was to investigate the effect of tocopherol extraction of Lepidium sativum seeds on the fertility of adult male rabbit. The In Vivo study included the estimation of the Medium Effect Dose (MED50) for tocopherol extraction by using Dose-Response Curve. The mean of MED50 was 33.6    mg/kg body weight (b.w.) of tocopherol. The results showed a significant increase (P  in testicular sperm concentration, epididymus sperm concentration and in the sperm count per gm of the testis, sperm motility percent, grade activity, sperm viability percent. While it was found a decrease in abnormal sperm morphology percent of epididymis caudal at MED50 of tocopherol. Our results reveal that due to tocopherol administration; male rabbits fertility increases, thus being useful to any animal, mammals as well as human being.  Keywords: Lepidium sativum, seeds, tocopherol, rabbits, sperm parameters

Changes in Sperm Parameters of Adult Male Rabbits by Phenol Extract of Lepidium Sativum Seeds

This research included the impact of phenol extract of Lepidium sativum seeds in sperm parameters of adult male rabbit. The In Vivo study included the estimation of the Medium Effect Dose (MED50) for phenol extraction by using Dose-Response Curve. The mean of MED50 was 36.1 mg /kg body weight (b.w.) of phenol. The results showed a significant increase (P  in testicular sperm concentration, epididymus sperm concentration and in the sperm count per gm of the testis, sperm motility percent, grade activity, sperm viability percent,and abnormal sperm morphology percent of epididymis caudal at MED50 of phenol.  The results reveal that supplement with low doses of phenol could be enhance rabbit fertility. Keywords:Lepidium sativum, seeds, phenol, soxhlet device, rabbits, sperm parameter

Immigration policy and the role of political discourses in the relationship between foreign nationals and crime in England and wales

Significant criminological attention has been given to the relationship between immigration and crime. However, this relationship has not been researched in the UK to any great extent, and consequently the information on the UK context is limited. This research investigates how the criminality of foreign nationals have been constructed by examining the nature of immigration policy, foreign criminality discourses, and the media in the UK to understand how crime in particular has been used to define, refine, and inform control of immigrants. This study refers to the legislative, policy, and political factors that underpin this process, and particularly explains how immigration policy and political debates have emphasised the criminality of foreign nationals in the UK. In order to achieve these goals, this research reviews a brief history of British immigration policy and legislation and outlines the connections made between foreign nationals and non-immigration criminal offences. In addition, secondary data from different British institutions and data collected via the Freedom of Information Act 2000 have been used to illustrate the level of foreigners’ criminality as well as the type of crimes compared to the British representation. Finally, Parliamentary debates and related political discourses have been used to examine the role of politics has in reinforcing the relationship between foreign nationals and crime and elevating negative public sentiment and the relationship with media reports. This research highlights the limitations of existing data relating to the criminality of foreign nationals in offending records in England and Wales, partly due to the disorganised recording of offender nationality. This study reveals that nationality is the new racism; whilst immigration has become a central focus in political and public discourses on crime they as a group in statistical terms exhibit low levels of offending but are more likely to be imprisoned for less serious crimes. The relationship between foreign nationals and crimes is thus a political issue rather than a legal one. As such, foreign nationals supposed criminality has been used to control immigration, avoid the blame of failing policies, gain electoral votes, and facilitate changes in immigration and crime policies.Ministry of Higher Education and Scientific Research in Ira

The correlation between Lactate dehydrogenase activity and sperm concentration in the seminal plasma of infertile men.

This study  included 43 semen samples collected from sub-fertile and 10 samples of fertile men, after the abstinence period (3 to 5 days); it was conducted in the laboratory of Babylon Maternity and children, and private laboratories during the period from October 2016 to March 2017.      The study was aimed to expose for reasons of unexplained infertility in most cases, through valued  the correlation between LDH activity and sperm concentration in the seminal plasma of infertile men and in comparison it with fertile men.     The results revealed significant differences (P˂0.05) in an average of the activity level of Lactate dehydrogenase enzyme between the different groups, the highest level was shown in the groups of fertile and normospermia and the lowest level in the oligospermia and oligo-asthenospermia, also revealed a significant negative correlation (P˂0.05) between LDH activity and sperm concentration in the seminal plasma of oligo-asthenospermia, the negative correlation observed in the group of normospermia and oligospermia while fertile men has positive correlation

Effect of varicocelectomy on sperm parameters, oxidative stress and Chromatin maturity in seminal fluid of infertile patients with varicocele

This study aimed to determine the effect of varicocelectomy on sperm parameters, oxidant- antioxidant status and chromatin maturity percent. The current study has been conducted on 154 infertile patients complaining from varicocele and varicocelomized men in addition to 25 fertile men as control. The results revealed significant decrease (

Study Effects of Contraceptives On Serum Electrolytes and lipid profile in Samarra City

This study included ( 150 ) samples of women used Contraceptives in  (Samaraa General Hospital) (30) blood draw pulled from healthy women as  Control sample. The samples were divided into three groups; the first group: -(60) women used combined oral contraceptive pill (COCs)  the second group: -(60) women used Progesterone Only Pills(POPs). The third group was the healthy women. The results of the study indicated significant numbers decrease in the Concentration of the Potassium Ion at level (P <0.001) and significant increase in the Concentration of the Sodium Ion at level (P <0.001) when compared to the control group. The results revealed significant decrease in the proteins of the blood (Total protein, Albumin) at level (P <0.001)when compared to the control group. while the results showed a rise in the concentration level of Cholesterol, Triglyceride at level (P <0.001)and significant decrease in the HDL when compared to the control group

Study Effects of Contraceptives On Serum Electrolytes and lipid profile in Samarra City

This study included ( 150 ) samples of women used Contraceptives in  (Samaraa General Hospital) (30) blood draw pulled from healthy women as  Control sample. The samples were divided into three groups; the first group: -(60) women used combined oral contraceptive pill (COCs)  the second group: -(60) women used Progesterone Only Pills(POPs). The third group was the healthy women. The results of the study indicated significant numbers decrease in the Concentration of the Potassium Ion at level (P <0.001) and significant increase in the Concentration of the Sodium Ion at level (P <0.001) when compared to the control group. The results revealed significant decrease in the proteins of the blood (Total protein, Albumin) at level (P <0.001)when compared to the control group. while the results showed a rise in the concentration level of Cholesterol, Triglyceride at level (P <0.001)and significant decrease in the HDL when compared to the control group

Engineering students' readiness to transition to emergency online learning in response to COVID-19: Case of Qatar

This study examined engineering students' initial readiness to transition to emergency online learning in response to COVID-19 in Qatar. A theoretical framework is proposed for understanding the factors influencing students' readiness for change. Sequential explanatory mixed-method research was conducted, with 140 participants completing an online survey, of which 68 also contributed written reflections and 8 participated in semi-structured interviews. Exploratory factor analysis displayed a four-factor structure, including initial preparedness and motivation for online learning, self-efficacy beliefs about online learning, self-directed learning online, and support. The qualitative outcomes supported the four factors and provided further insight into their varied and nuanced manifestation. In accounting for the perceived impact of the factors on readiness, significant differences were identified regarding pedagogical mode, with students enrolled in PBL courses reporting higher readiness than those from non-PBL courses. The practical implications for preparing students for future emergency online learning are discussed. 2020 by the authors.Scopu

Protein-Tyrosine Kinase Activity Profiling in Knock Down Zebrafish Embryos

BACKGROUND: Protein-tyrosine kinases (PTKs) regulate virtually all biological processes. PTKs phosphorylate substrates in a sequence-specific manner and relatively short peptide sequences determine selectivity. Here, we developed new technology to determine PTK activity profiles using peptide arrays. The zebrafish is an excellent model system to investigate signaling in the whole organism, given its wealth of genetic tools, including morpholino-mediated knock down technology. We used zebrafish embryo lysates to determine PTK activity profiles, thus providing the unique opportunity to directly compare the effect of protein knock downs on PTK activity profiles on the one hand and phenotypic changes on the other. METHODOLOGY: We used multiplex arrays of 144 distinct peptides, spotted on a porous substrate, allowing the sample to be pumped up and down, optimizing reaction kinetics. Kinase reactions were performed using complex zebrafish embryo lysates or purified kinases. Peptide phosphorylation was detected by fluorescent anti-phosphotyrosine antibody binding and the porous chips allowed semi-continuous recording of the signal. We used morpholinos to knock down protein expression in the zebrafish embryos and subsequently, we determined the effects on the PTK activity profiles. RESULTS AND CONCLUSION: Reproducible PTK activity profiles were derived from one-day-old zebrafiish embryos. Morpholino-mediated knock downs of the Src family kinases, Fyn and Yes, induced characteristic phenotypes and distinct changes in the PTK activity profiles. Interestingly, the peptide substrates that were less phosphorylated upon Fyn and Yes knock down were preferential substrates of purified Fyn and Yes. Previously, we demonstrated that Wnt11 knock down phenocopied Fyn/Yes knock down. Interestingly, Wnt11 knock down induced similar changes in the PTK activity profile as Fyn/Yes knock down. The control Nacre/Mitfa knock down did not affect the PTK activity profile significantly. Our results indicate that the novel peptide chip technology can be used to unravel kinase signaling pathways in vivo