205 research outputs found

    On a Conjecture of Rapoport and Zink

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    In their book Rapoport and Zink constructed rigid analytic period spaces FwaF^{wa} for Fontaine's filtered isocrystals, and period morphisms from PEL moduli spaces of pp-divisible groups to some of these period spaces. They conjectured the existence of an \'etale bijective morphism FaFwaF^a \to F^{wa} of rigid analytic spaces and of a universal local system of QpQ_p-vector spaces on FaF^a. For Hodge-Tate weights n1n-1 and nn we construct in this article an intrinsic Berkovich open subspace F0F^0 of FwaF^{wa} and the universal local system on F0F^0. We conjecture that the rigid-analytic space associated with F0F^0 is the maximal possible FaF^a, and that F0F^0 is connected. We give evidence for these conjectures and we show that for those period spaces possessing PEL period morphisms, F0F^0 equals the image of the period morphism. Then our local system is the rational Tate module of the universal pp-divisible group and enjoys additional functoriality properties. We show that only in exceptional cases F0F^0 equals all of FwaF^{wa} and when the Shimura group is GLnGL_n we determine all these cases.Comment: v2: 48 pages; many new results added, v3: final version that will appear in Inventiones Mathematica

    The epidemiological transition in Antananarivo, Madagascar: an assessment based on death registers (1900–2012)

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    Background: Madagascar today has one of the highest life expectancies in sub-Saharan Africa, despite being among the poorest countries in the continent. There are relatively few detailed accounts of the epidemiological transition in this country due to the lack of a comprehensive death registration system at the national level. However, in Madagascar's capital city, death registration was established around the start of the 20th century and is now considered virtually complete. Objective: We provide an overview of trends in all-cause and cause-specific mortality in Antananarivo to document the timing and pace of the mortality decline and the changes in the cause-of-death structure. Design: Death registers covering the period 1976–2012 were digitized and the population at risk of dying was estimated from available censuses and surveys. Trends for the period 1900–1976 were partly reconstructed from published sources. Results: The crude death rate stagnated around 30‰ until the 1940s in Antananarivo. Mortality declined rapidly after the World War II and then resurged again in the 1980s as a result of the re-emergence of malaria and the collapse of Madagascar's economy. Over the past 30 years, impressive gains in life expectancy have been registered thanks to the unabated decline in child mortality, despite political instability, a lasting economic crisis and the persistence of high rates of chronic malnutrition. Progress in adult survival has been more modest because reductions in infectious diseases and diseases of the respiratory system have been partly offset by increases in cardiovascular diseases, neoplasms, and other diseases, particularly at age 50 years and over. Conclusions: The transition in Antananarivo has been protracted and largely dependent on anti-microbial and anti-parasitic medicine. The capital city now faces a double burden of communicable and non-communicable diseases. The ongoing registration of deaths in the capital generates a unique database to evaluate the performance of the health system and measure intervention impacts

    Comunità cristiane nell’islam arabo. La sfida del futuro

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    Preesistenti all'islamizzazione del Medio Oriente, le comunità cristiane costituiscono tuttora un importante elemento di pluralismo, sebbene oggi a rischio di sopravvivenza, nelle società arabe a maggioranza musulmana. Il volume presenta il ruolo storico delle comunità cristiane orientali nelle rispettive società arabe, la loro funzione di intermediazione culturale tra Oriente e Occidente e la discriminazione giuridica e sociale subìta con l'avvento dell'islam.- Indice #4- Introduzione, Andrea Pacini #10- Gli arabi cristiani: dalla questione d’Oriente alla recente geopolitica delle minoranze, Joseph Maïla #38- I cristiani arabi dell’Oriente: una prospettiva demografica, Philippe Fargues #64- Le comunità cristiane, soggetti attivi della società araba nel corso della storia, Samir Khalil Samir #84- Le chiese del Medio Oriente: origini e identità, tra radicamento nel passato e apertura al presente, Jean Corbon #110- Il diritto dello stato/nazione e lo status dei non musulmani in Egitto e in Siria, Bernard Botiveau #130- L’emigrazione degli arabi cristiani: dimensioni e cause dell’esodo, Bernard Sabella #148- La produzione culturale dei cristiani arabi oggi: espressione di identità nella società a maggioranza musulmana, Camille Hechaïmé #178- Le dinamiche politiche dei copti: rendere la comunità un protagonista atti, Dina El Khawaga #196- La posizione e il ruolo attuale dei copti nell’economia egiziana: tradizioni e specializzazioni, Adel A. Beshai #216- Le dinamiche dei cristiani libanesi: tra il paradigma delle ‘āmmiyyāt e il paradigma Hwayyek, Elizabeth Picard #226- Le comunità cristiane e la situazione economica e sociale in Libano, Boutros Labaki #250- Dinamiche comunitarie e sociopolitiche dei cristiani arabi in Giordania, in Israele e nei territori palestinesi autonomi, Andrea Pacini #290- I cristiani di Siria, Habib Moussalli #320- I cristiani in Iraq, Yūsuf Habbi #330- Il contributo delle comunità arabo-cristiane al futuro delle società arabe del Medio Oriente: alcune prospettive, Maurice Borrmans #342- I riti delle chiese orientali #356- Glossario #376- Riferimenti bibliografici #40

    The Composition of the Cuticular and Internal Free Fatty Acids and Alcohols from Lucilia sericata Males and Females

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    GC, GC–MS, and HPLC–LLSD analyses were used to identify and quantify cuticular and internal lipids in males and females of the blow-fly (Lucilia sericata). Sixteen free fatty acids, seven alcohols and cholesterol were identified and quantitatively determined in the cuticular lipids of L. sericata. Cuticular fatty acids ranged from C6 to C20 and included unsaturated entities such as 16:1n-9, 18:1n-9, 20:4n-3 and 20:5n-3. Cuticular alcohols (only saturated and even-numbered) ranged from C12 to C20 in males and C10 to C22 in females. Only one sterol was found in the cuticular lipids of both males and females. 23 free fatty acids, five alcohols and cholesterol were identified in the internal lipids. Internal fatty acids were present in large amounts—7.4 mg/g (female) and 10.1 mg/g (male). Only traces of internal alcohols (from C14 to C26 in males, from C14 to C22 in females) were found in L. sericata. Large amounts of internal cholesterol were identified in L. sericata males and females (0.49 and 0.97 mg/g of the insect body, respectively)

    Infection of Anopheles gambiae mosquitoes with entomopathogenic fungi: effect of host age and blood-feeding status

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    Physiological characteristics of insects can influence their susceptibility to fungal infection of which age and nutritional status are among the most important. An understanding of host–pathogen interaction with respect to these physiological characteristics of the host is essential if we are to develop fungal formulations capable of reducing malaria transmission under field conditions. Here, two independent bioassays were conducted to study the effect of age and blood-feeding status on fungal infection and survival of Anopheles gambiae s.s. Giles. Mosquitoes were exposed to 2 × 1010 conidia m−2 of oil-formulated Metarhizium anisopliae ICIPE-30 and of Beauveria bassiana I93-825, respectively, and their survival was monitored daily. Three age groups of mosquitoes were exposed, 2–4, 5–8, and 9–12 days since emergence. Five groups of different feeding status were exposed: non-blood-fed, 3, 12, 36, and 72 h post-blood feeding. Fungal infection reduced the survival of mosquitoes regardless of their age and blood-feeding status. Although older mosquitoes died relatively earlier than younger ones, age did not tend to affect mosquito susceptibility to fungal infection. Non-blood-fed mosquitoes were more susceptible to fungus infection compared to all categories of blood-fed mosquitoes, except for those exposed to B. bassiana 72 h post-blood feeding. In conclusion, formulations of M. anisopliae and B. bassiana can equally affect mosquitoes of different age classes, with them being relatively more susceptible to fungus infection when non-blood-fed

    Socialization, Adaptation, Transnationalism, and the Reproductive Behavior of Sub-Saharan African Migrants in France

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    Background:  Migrants from Sub-Saharan Africa (SSA) move from a region with high fertility to regions with low fertility. Yet very few studies have examined the reproductive behavior of international migrants from SSA. Objective: This study examines the roles of origin and destination socialization on the fertility and fertility ideals of SSA migrants in France. The study draws on measures of assimilation to systematically examine the effects of socialization and adaptation as well as transnationalism for the effects of sustained origin ties.  Methods: Data are from the TEO (“Trajectoires et Origines”) survey conducted in France (2008/2009). Logistic regression is used to examine current fertility (the odds of having a birth in the preceding five years), and Poisson regression is used to examine cumulative fertility (children ever born) and fertility ideals (reported ideal number of children in a family). Results: Controlling for sociodemographic factors, first-generation SSA migrants have higher fertility than second-generation SSA migrants and non-immigrants. But first and second-generation SSA migrants have higher fertility ideals than non-immigrants. Among SSA migrants, first and second-generation migrants do not differ in fertility and fertility ideals when adaptation is accounted for. Most measures of adaptation are negatively associated with actual fertility and fertility ideals. Transnationalism is associated with higher fertility ideals but less so with actual fertility. Conclusion: The study finds some evidence for origin socialization, but the findings are more strongly supportive of adaptation to the host society. Origin socialization appears to have a stronger influence on fertility ideals than actual fertility

    Electroanalysis may be used in the Vanillin Biotechnological Production

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    This study shows that electroanalysis may be used in vanillin biotechnological production. As a matter of fact, vanillin and some molecules implicated in the process like eugenol, ferulic acid, and vanillic acid may be oxidized on electrodes made of different materials (gold, platinum, glassy carbon). By a judicious choice of the electrochemical method and the experimental conditions the current intensity is directly proportional to the molecule concentrations in a range suitable for the biotechnological process. So, it is possible to imagine some analytical strategies to control some steps in the vanillin biotechnological production: by sampling in the batch reactor during the process, it is possible to determine out of line the concentration of vanillin, eugenol, ferulic acid, and vanillic acid with a gold rotating disk electrode, and low concentration of vanillin with addition of hydrazine at an amalgamated electrode. Two other possibilities consist in the introduction of electrodes directly in the batch during the process; the first one with a gold rotating disk electrode using linear sweep voltammetry and the second one requires three gold rotating disk electrodes held at different potentials for chronoamperometry. The last proposal is the use of ultramicroelectrodes in the case when stirring is not possible
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