Acute toxicity test of anthelmintic herbal on Artemia salina larvae

Jamu X is a traditional medicine that is believed to provide anti-inflammatory effects, contains natural ingredients such as Curcuma xanthorrhiza Robx and Curcuma aeruginaosa Robx, has long been used to treat worm infections in children, but it has not passed preclinical tests. The use of traditional medicine in Indonesia has also increased to 44.3%, 55.3% in liquid form, and the rest in powder form. Therefore, this study aimed to determine the potential acute toxicity of Jamu X to Artemia salina larvae presented as its    Furthermore, to determine the damaged parts of the larval organs using the Brine Shrimp Lethality Test (BSLT) method. This experimental study used 10000, 1000, 100, 10, 1, and 0.1 ppm, and each concentration contained 10 Artemia salina larvae. Then, we obtained the upper limit of 10,000 and the lower limit of 1000. In the following test, the larvae were grouped into six groups consisting of 10 Artemia salina larvae, and each group was given Jamu "X" solution with a series of concentrations 10000, 7820, 5640, .168, 1780, and 1000 ppm. Mortality data of Artemia salina larvae were analyzed by probit analysis to determine the value of   . The results of this study showed the   value was 1548.81 µg/mL, and damage was found in the thorax, antennae, antennule, stigma, and abdomen. It shows that Jamu X does not have the potential for acute toxicity or is non-toxic, which is indicated by the value of   > 1000 ppm

Acute Toxicity Test of The Jamu TurmericTamarind on Artemia Salina Leach Larvae

Jamu is an ingredient from plant, animal material, mineral material, or a mixture of these ingredients for treatment based on experience. One of the jamu that are often consumed by Indonesian people, especially women, is the turmeric tamarind jamu. The turmeric and tamarind jamu is believed by most women to relieve pain during menstruation period. However, its current use has not been accompanied by the optimum dosage and side effects. Therefore, the toxicity test was carried out as an initial screening to predict the toxic levels that might be caused by the turmeric tamarind jamu. In this study, the bioactive substances in turmeric tamarind jamu will be identified, as well as the level of toxicity based on the LC50 value. Using variations in extract concentration, this study used a fully randomized approach. The powdered sample of turmeric tamarind jamu brand X was dissolved in water and then tested for phytochemical screening. Phytochemical screening including flavonoids, alkaloids, tannins, steroids/terpenoids, and saponins screening was carried out qualitatively, the Brine Shrimp Lethality Test (BSLT) method was used to carry out the toxicity.The results of the phytochemical screening showed that the turmeric tamarind jamu contains alkaloids, flavonoids, tepenoid, steroid and tannins. The results of the toxicity test of the turmeric tamarind jamu showed the LC50 value in 3366.656 ppm and classified as non-toxic because it had LC50 value more than 1000 ppm

COVID-19 Vaccine Acceptance in A Private Islamic Boarding School, West Nusa Tenggara

The COVID-19 vaccination program began in Indonesia in 2020, but it is still unknown how well it has been received by particular communities in places like the West Nusa Tenggara region's Islamic boarding schools. This research aimed to identify the characteristics and factors that contribute to the COVID-19 vaccine's acceptance at the Nurul Islam Sekarbela Islamic Boarding School. In August 2022, a cross-sectional survey was conducted on a stratified random sample of chosen boarding school students using a validated questionnaire. Data on demographic factors, COVID-19 history, religious acceptance, and opinions were all examined descriptively. A total of 124 students, or 62%, gave their informed permission. Based on the findings, it was determined that the Nurul Islam Sekarbela Islamic Boarding School's level of acceptance of the COVID-19 vaccine is still considered low (35%) and in doubt (65%). Acceptance of vaccines is mostly influenced by efficacy, safety, and family recommendations. Acceptance of vaccines is impeded by the dominant fatalistic religious mindset

Optimalisasi Limbah Rumah Tangga Dalam Pembuatan Pupuk Organik Cair di Desa Perian

Kuliah Kerja Nyata (KKN) is one of the community service activities carried out by universities. In the KKN activities carried out in Perian Village, Montong Gading District, East Lombok Regency, West Nusa Tenggara Province, a group of Mataram University students carried out various activities, one of which was turning organic waste into liquid organic fertilizer. The purpose of implementing this activity is to reduce organic waste, utilize organic waste to become valuable goods, and help plant fertilization. The method used in the manufacture of liquid organic fertilizer is fermentation by mixing organic waste in the form of vegetable and fruit waste with rice washing water, molasses, and EM4. After that it is fermented for 2 weeks to produce liquid organic fertilizer. The results of this activity are liquid organic fertilizers that have undergone simple tests that can accelerate plant growth. The results of the activities above show that this KKN activity has been able to answer several problems in Perian village related to the amount of organic waste produced, organic waste management, and plant fertilization.Kuliah Kerja Nyata (KKN) merupakan salah satu kegiatan pengabdian masyarakat yang dilaksanakan oleh perguruan tinggi. Dalam kegiatan KKN yang dilaksanakan di Desa Perian, Kecamatan Montong Gading, Kabupaten Lombok Timur, Provinsi Nusa Tenggara Barat, kelompok mahasiswa Universitas Mataram melaksanakan berbagai kegiatan salah satunya mengubah limbah rumah tangga yaitu limbah organik berupa sayur dan buah-buahan menjadi pupuk organik cair. Tujuan pelaksanaan kegiatan ini adalah untuk mengurangi limbah organik, memanfaatkan limbah organik menjadi barang berharga, dan membantu penyuburan tanaman. Metode yang digunakan dalam pembuatan pupuk organik cair ini adalah fermentasi dengan cara mencampurkan limbah organik berupa limbah sayur dan buah-buahan dengan air cucian beras, molase, dan EM4. Setelah itu difermentasi selama 2 minggu hingga dihasilkan pupuk organik cair. Hasil kegiatan ini adalah pupuk oraganik cair yang telah mengalami pengujian sederhana yang dapat menyuburkan tumbuh tanaman. Hasil kegiatan di atas menunjukkan bahwa kegiatan KKN ini telah mampu menjawab beberapa masalah yang ada di desa Perian terkait jumlah limbah organik yang dihasilkan, pengelolaan limbah organik, dan penyuburan tanaman