The School We Want: evolution or change? A consideration about italian school

Un'analisi dei programmi di letteratura italiana svolti nei licei di Pis

Cromatismo, ritmo, memoria: sulla narrativa di Sergio Atzeni

Sergio Atzeni’s works are many and really heterogeneous, both in style and contents. But if we dig up deeply into his texts, we discover that the currents followed by the author are always the same, and that texts that are apparently different have actually significant common aspects.Le opere di Sergio Atzeni sono numerose e molto eterogenee, sia nello stile che nei contenuti. Ma se andiamo a scavare nel profondo, ci rendiamo conto che i filoni seguiti dall’autore sono sempre gli stessi, e che esiti testuali apparentemente distinti hanno in realtà importanti aspetti in comune

"La Coscienza di Zeno": per l’intertestualità di Ritmo Lento

One of Carmen Martín Gaite’s interest was the Italian literature. There are many studies that focused their attention on the influence that this literature has in the Carmen Martín Gaite’s work. But the influence of Italo Svevo is forgotten. In this work I want to focus my attention in the relationship between La coscienza di Zeno and Ritmo Lento.Nonostante sia noto l’interesse per la letteratura italiana da parte di Carmen Martín Gaite, e nonostante quest’interesse sia stato registrato da numerosi critici che ne hanno visto il riflesso nell’opera dell’autrice salamantina, l’influenza dell’opera di Italo Svevo non è mai stata studiata in maniera sistematica e approfondita. Eppure, la stessa Martín Gaite cita lo scrittore triestino come esempio. Nello studio che segue si vuole mettere in luce come La coscienza di Zeno costituisca, sia dal punto di vista strutturale sia dal punto di vista tematico, l’intertestualità fondamentale della composizione di Ritmo Lento

The S-layer protein DR_2577 binds deinoxanthin and under desiccation conditions protects against UV-radiation in Deinococcus radiodurans

Deinococcus radiodurans has the puzzling ability to withstand over a broad range of extreme conditions including high doses of ultraviolet radiation and deep desiccation. This bacterium is surrounded by a surface layer (S-layer) built of a regular repetition of several proteins, assembled to form a paracrystalline structure. Here we report that the deletion of a main constituent of this S-layer, the gene DR_2577, causes a decrease in the UVC resistance, especially in desiccated cells. Moreover, we show that the DR_2577 protein binds the carotenoid deinoxanthin, a strong protective antioxidant specific of this bacterium. A further spectroscopical characterization of the deinoxanthin-DR_2577 complex revealed features which could suggest a protective role of DR_2577. We propose that, especially under desiccation, the S-layer shields the bacterium from incident ultraviolet light and could behave as a first lane of defense against UV radiation

Networked Intimacy. Intimacy and Friendship among Italian Facebook users

In this paper, we describe the results of a qualitative study conducted with 120 Italian Facebook users to investigate how Facebook enables people to achieve a mutually constitutive intimacy with their own friendship network: a negotiation of intimacy in public through self-disclosure, where the affordances of the platform are useful to elicit significant reactions, validations and demonstrations of affection from others. We observed that, in order to achieve various levels of intimacy on Facebook, people engage in various strategies: Showing rather than telling, Sharing implicit content, Tagging, Expectation of mutual understanding and Liking. These strategies produce a collaborative disclosure that relies on others’ cooperation to maintain the boundaries between private and public space. Based on these premises, we developed a framework of collaborative strategies for managing public intimacy that both systematizes and extends the findings identified in previous studies of intimacy on Facebook. We describe this framework as networked intimacy and we discuss the consequences of it in the light of already existing research on online self-disclosure

Bronze production in the Iron Age of the Iberian Peninsula: The case of El Castru, Vigaña (Asturias, NW Spain)

Bronze production during the Iron Age of the Iberian Peninsula is characterised by the use of a relatively simple technology, based on crucible-furnaces. In an area rich in mineral resources, bronze was produced on a small scale and within settlements, to be used for ritual, ornamental and functional objects. Here we present an analytical study of slagged crucibles, small slag nodules and casting spillage fromthe Iron Age hillfort of El Castru, in Vigaña (Asturias, NW Iberia), with a particular focus on the technology of bronze production. The study sought to contribute to our understanding of Pre-Roman metallurgical activities in the region, as a case in point to discuss broader prehistoric traditions of bronze-making. The results showthat the technology and scale of bronze production at this hillfort are coherentwith the pattern described for much of prehistoric metallurgy in Iberia, with the -direct production of copper alloys by cementation and co-smelting of mineral ores. The results also illustrate some of the challenges encountered when attempting to identify metallurgical processes through the analyses of crucible residues, and propose some criteria to facilitate future studies.Peer reviewe

Neutralizing antibody response during acute and chronic hepatitis C virus infection

Little is known about the role of Abs in determining the outcome of hepatitis C virus (HCV) infection. By using infectious retroviral pseudotypes bearing HCV glycoproteins, we measured neutralizing Ab (nAb) responses during acute and chronic HCV infection. In seven acutely infected health care workers, only two developed a nAb response that failed to associate with viral clearance. In contrast, the majority of chronically infected patients had nAbs. To determine the kinetics of strain-specific and crossreactive nAb emergence, we studied patient H, the source of the prototype genotype 1a H77 HCV strain. An early weak nAb response, specific for the autologous virus, was detected at seroconversion. However, neutralization of heterologous viruses was detected only between 33 and 111 weeks of infection. We also examined the development of nAbs in 10 chimpanzees infected with H77 clonal virus. No nAb responses were detected in three animals that cleared virus, whereas strain-specific nAbs were detected in six of the seven chronically infected animals after approximately 50 weeks of infection. The delayed appearance of high titer crossreactive nAbs in chronically infected patients suggests that selective mechanism(s) may operate to prevent the appearance of these Abs during acute infection. The long-term persistence of these nAbs in chronically infected patients may regulate viral replication

Controllo genetico della stagionalità riproduttiva in ovini di razze autoctone

Genetic control of reproductive seasonality in native sheep Reproductive physiology in sheep can change with latitudes. It’s normally characterized by seasonality, and is regulated by photoperiod’s exposure. The aim of this study was to investigate the GPR54, MTNR1a and KiSS1 genes polymorphisms in Sardinian and Slovenian local breeds, in order to determine if there is an association with reproductive seasonality. The PCR-SSCP analysis was carried out on 250, 130, and 106 bp fragment, respectively from GPR54 exons 1 and 2 and KiSS1 exon 1, while for the 824 bp fragment from MTNR1A gene exon 2 was also added RFLP analysis, using MnlI and Rsa1 endonucleases. Some polymorphic sites were found: G1035A at the Kiss1 gene exon 1 leading to GG (75,7 %), GA (21,3 %) and AA (3 %) genotypes; C606T and G612A at the MTNR1A exon 2, leading to genotypes CC (42,5 %), CT (31 %) and TT (26,5 %), and GG (51,5 %), GA (34,75%) and AA (13,75 %), respectively. These two last polymorphisms showed to influence the reproductive recovery in Sarda breed. No polymorphism was found in the exon 1 and 2 of the GPR54 gene. Statistical analysis showed no correlation between genotypes and reproductive seasonality in Slovenian breed sheep. The effect of the gene genotypes, in Slovenian s sheeps, maybe was masked by management e of males put inside the group during decreasing of photoperiod, therefore already favorable at the beginning of the reproductive activity. The low frequency of genotypes found for KISS1 and GPR54 genes does not allow us to highlight possible influences of these mutations on reproductive activity

Simultaneous occlusion of three cilioretinal arteries following scleral buckling surgery under local anesthesia

BACKGROUND: Cilioretinal artery (CRA) occlusions are rare in young patients. In these cases, the most commonly associated causes are considered to be the same as those implicated in central retina artery occlusions, such as vasculitic processes, migraine, cardiac disorder, and coagulation abnormality. The aim of this article was to report for the first time the medical records and investigational results of an unusual case of simultaneous occlusion of three CRAs after scleral buckling surgery under local anesthesia. METHODS: A complete ophthalmic examination, including color fundus image, fundus fluorescein angiography, optical coherence tomography, visual field, as well as systemic and laboratory assessments, was performed. RESULTS: A case of contemporaneous blockage of three CRAs after ab externo surgery for retinal detachment in a 29-year-old Caucasian woman was reported. The interdisciplinary approach and the imaging results have allowed us the clinical definition of such a very rare case. CONCLUSION: Here, we reported that optical coherence tomography is an indispensable tool to better delineate the pathological process and follow atrophic changes in the macula, especially in cases in which fundus fluorescein angiography and systemic tests may be poorly informativ