Complexity Growth with Lifshitz Scaling and Hyperscaling Violation

Using complexity=action proposal we study the growth rate of holographic complexity for Lifshitz and hyperscaling violating geometries. We will consider both one and two sided black branes in an Einstein-Maxwell-Dilaton gravitational theory. We find that in either case Lloyd's bound is violated and the rate of growth of complexity saturates to a value which is greater than twice the mass of the corresponding black brane. This value reduces to the mass of the black brane in the isotropic case. We show that in two sided black brane the saturation happens from above while for one sided black brane it happens from below.Comment: 17 pages, 4 figures, v2: typos corrected, references added, v3: Minor corrections, New counter terms added that also contribute to the rate of complexity growth. The conclusion is not changed, now 19 pages, v4: matches published versio

Comparison between Low Flow Indices Using FL Approach and Low Flow Frequency Curve (A Case Study of Gharesou River Catchment)

Selection of low flow is necessary for water resource management, water supply planning, and watershed ecosystem restoration. In this study, FL approach was used, which is based on minimum flows and flow duration curve (Q80) categories. This approach was compared with the conventional 7Q10 approach used in low flow selection. For this purpose, the daily flow series from Gharesou catchment was applied. Low flow frequency analysis related to 7Q10 approach was done by fitting various distribution functions and using three frequency software, including HYFA, SMADA, and Easy fit. The results of both approaches show that low flows increased as time elapsed and the recurrence probability of low flow increased while the recurrence interval of low flow decreased as time elapsed. In addition, a low flow decline from 1971 to 2000 observed as 1.57 m3/s and 2.46 m3/s for 7Q10 and FL approaches respectively. The 7Q10 approach lead to selecting extremely low flows (approximately zero). The FL approach used in this study, could result in selecting low flows, considering role of the environment and minimum flow to protect the ecosystem of the catchment

Solid silica-based sulfonic acid: A remarkably efficient heterogeneous reusable catalyst for the one-pot synthesis of 2H-indazolo[2,1-b]phthalazine-triones

A novel, efficient and one-pot method for preparation of 2H-indazolo [2,1-b] phthalazine-trione derivatives is reported using solid silica-based sulfonic acid as an effective heterogeneous catalyst under thermal and solvent-free conditions. This method has the advantages of high yields, a cleaner reaction, simple methodology, easy work-up and greener conditions. The catalyst is easily prepared, stable (up to 300 C), reusable and efficient under the reaction conditions. Keywords: Dimedone, 2H-indazolo[2,1-b]phthalazine-trione, indazolophthalazine, solid silica-based sulfonic aci

A histopathological study of smoking on free gingiva in patients with moderate to severe periodontitis

Introduction Cigarette smoking has been recognized to be a risk factor for progression of periodontal disease. Due to less inflammation and bleeding in the presence of clinical signs of periodontal disease in smokers than in nonsmokers and given the conflicting results of studies on changes in the epithelium and gingival connective tissue by smoking, this study was performed to evaluate the thickness and keratosis on the epithelium of free and sulcular gingival tissue in smokers and nonsmokers patients with moderate to advanced periodontitis. Methods: In this cross sectional study, biopsies were obtained from palatal gingival of 60 patients with moderate to advanced periodontitis (30 smokers and 30 nonsmokers). These biopsies were histologically processed, serially sectioned at 5 microns, stained with H. E. and examined by image analysis software (analysis-SL-starter), which was used to perform the morphometric evaluation of the outer and inner epithelial thickness, keratosis and vascularity in connective tissue. The data were analyzed with SPSS 17, t-test, Mann-Whitney Test, and Pearson correlation. p<0.05 was considered significant. Results: Histopathological examination showed significant association between smoking and CAL (p=0.048), keratosis on outer epithelium (p=0.020) and mean of thickness of outer (p=0.023) and inner (p<0.001) marginal gingival epithelium but gingival vascular density in nonsmokers was more than smokers (p=0.002). Collagenized connective tissue was observed in smokers more than nonsmokers. (p<0.001) Conclusions: It seems that the reduction of the clinical signs of inflammation in the gingival tissue of smokers is due to changes in gingival epithelium and connective tissue from smoking

CN2F: A Cloud-Native Cellular Network Framework

Upcoming 5G and Beyond 5G (B5G) cellular networks aim to improve the efficiency and flexibility of mobile networks by incorporating various technologies, such as Software Defined Networking (SDN), Network Function Virtualization (NFV), and Network Slicing (NS). In this paper, we share our findings, accompanied by a comprehensive online codebase, about the best practice of using different open-source projects in order to realize a flexible testbed for academia and industrial Research and Development (R&D) activities on the future generation of cellular networks. In particular, a Cloud-Native Cellular Network Framework (CN2F) is presented which uses OpenAirInterface's codebase to generate cellular Virtual Network Functions (VNFs) and deploys Kubernetes to disperse and manage them among some worker nodes. Moreover, CN2F leverages ONOS and Mininet to emulate the effect of the IP transport networks in the fronthaul and backhaul of real cellular networks. In this paper, we also showcase two use cases of CN2F to demonstrate the importance of Edge Computing (EC) and the capability of Radio Access Network (RAN) slicing

Prevalence and risk factors of urethral, penile, and scrotal cancers in Iranian men during 2004-2015: A national cancer registry-based study

Introduction: Urethral, penile, and scrotal cancers are rare and represent less than 1% of all malignancies. However, they are associated with a high mortality rate and have a significant effect on patients’ quality of life. Penile and urethral cancers comprise 0.6% of all urological cancers. Because of ethnic, geographical, and cultural diversity, risk factors and cancer patterns vary in different communities. We aimed to provide valid information on the prevalence, incidence, and epidemiology of urethral, penile, and scrotal cancers using the National Registry on Cancer of Iran. Methods: This retrospective study of 465 patients included all known cases of urethral, penile, and scrotal cancers from the Department of National Registry on Cancer at the Ministry of Health and Medical Education in Iran during 2004-2015. This study examined the demographic characteristics of patients and discussed the risk factors and possible causes of the above-mentioned cancers. Results: The mean ±SD age at the time of registration was 58.49±20.82 years. The highest and lowest proportions of cases belonged to Tehran/Alborz (14.2%) and Mazandaran (0.65%) provinces, Iran, respectively. Regarding the distribution of records according to a year of registration, these cancers were more prevalent in 2014, and less prevalent in 2004. Conclusion: Urethral, penile, and scrotal cancers were more common in Tehran and Alborz. There was a strong possibility that the prevalence of these cancers is linked to the industrial nature of Tehran and Alborz and the prevalence of human papillomavirus

Effect of Curcumin on Pediatric Intractable Epilepsy

ObjectivesEpilepsy is the most prevalent chronic neurologic disorder in children. One-third of patients with epilepsy do not respond to antiepileptic drugs. This condition is known as intractable epilepsy. Previous studies have shown the beneficial effects of curcumin in the treatment of epilepsy. There are no randomized controlled clinicaltrials assessing the use of curcumin in epilepsy. This study aimed to evaluate the effects of nanomicelle curcumin on intractable pediatric epilepsy. Materials &amp; Methods This double-blinded randomized crossover clinical trial was performed by a consecutive sampling to select 22 patients with intractable epilepsy divided into two groups. Patients received a daily dose of 4 mg/kg of curcumin or placebo as add-on therapy for 4 weeks. After a 2-week washout period, the treatment was replaced, and the new treatment was given for another 4 weeks. The SPSS software version 16 was used for statistical analysis. The study was approved by the Ethics Committee of Mashhad University of Medical Sciences, Iran Results A total of 22 children were enrolled in this study, 11 of which were boys. The mean age of the patients was 4.28±5 years. A female patient taking a placebo was excluded in the first week of the trial due to parental dissatisfaction. The most common type of seizure among our patients was a generalized myoclonic seizure (42.9%). The mean number of seizure attacks among the subjects was 68.76±69.26 preintervention and 39.85±39.41at the end of the intervention, which represents a statistically significant difference (P=0.01). Conclusion Nanomicelle curcumin reduced the number of seizures significantly. Our results imply that curcumin treatment can help treat patients wit intractable pediatric epilepsy

Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran

Background. Stroke is the second leading cause of death worldwide. The role of zinc as a new predictor of stroke was considered. Methods. This prospective study was conducted in Ayatollah Rouhani Hospital within a year on 100 stroke and 100 control patients. Findings. The difference in zinc serum level in two groups was significant (deficiency: 3 (3%) in patients versus 20 (20%) in control group, normal: 25 (25%) versus 54 (54%), and increased level: 72 (72%) versus 26 (26%); p<0.001). Difference in zinc serum levels was statistically significant with ischemic heart disease (deficiency: 0 cases (0%), normal: 8 cases (24%), increased level: 24 cases (75%), p=0.003). Increases in zinc serum level were significantly correlated with the frequency of hemorrhagic and ischemic patients (deficiency: 3 (3.3%) hemorrhagic versus 0 (0%) ischemic; normal: 19 (21%) versus 6 (60%), increased level: 68 (75.6%) versus 4 (40%); p=0.025). Regression logistics showed that ischemic heart disease (p<0.001; OR = 28.29, %95 CI: 5.53; 144.87), hyperlipidemia (p<0.001; OR = 0.26, %95 CI: 0.12; 0.56), and zinc serum level (p<0.001, OR = 15.53, %95 CI: 4.03; 59.83) each had a significant role. Conclusions. Babol stroke patients are prone to increased zinc serum level as a new parameter. Ischemic heart disease, increased levels of zinc, and hyperlipidemia were found to be probable predictor factors for stroke in Babol

Use of nanomaterials in the pretreatment of water samples for environmental analysis

The challenge of providing clean drinking water is of enormous relevance in today’s human civilization, being essential for human consumption, but also for agriculture, livestock and several industrial applications. In addition to remediation strategies, the accurate monitoring of pollutants in water sup-plies, which most of the times are present at low concentrations, is a critical challenge. The usual low concentration of target analytes, the presence of in-terferents and the incompatibility of the sample matrix with instrumental techniques and detectors are the main reasons that renders sample preparation a relevant part of environmental monitoring strategies. The discovery and ap-plication of new nanomaterials allowed improvements on the pretreatment of water samples, with benefits in terms of speed, reliability and sensitivity in analysis. In this chapter, the use of nanomaterials in solid-phase extraction (SPE) protocols for water samples pretreatment for environmental monitoring is addressed. The most used nanomaterials, including metallic nanoparticles, metal organic frameworks, molecularly imprinted polymers, carbon-based nanomaterials, silica-based nanoparticles and nanocomposites are described, and their applications and advantages overviewed. Main gaps are identified and new directions on the field are suggested.publishe