1,623 research outputs found

    A non-invasive method for measuring blood flow rate in superficial veins from a single thermal image.

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    Computer vision is a field that includes methods for processing, analyzing, acquiring and understanding images to produce numerical or symbolic information to develop methodologies and solutions for many problems in many fields. Here the concept of computer vision is being used for understanding certain human physiology and behaviors using thermal imaging alone or in conjunction with other imaging modalities. The applications of this work span a wide range of studies in human-machine interfacing vis-à-vis feedback controls that can be used to remotely determine whether a patient is in need of medical assistance or to help integrate young children with learning challenges into a public classroom setting that can require monitoring vital signs and physiological cues without the need for contact-based sensors such as electrocardiogram (ECG) or electroencephalogram (EEG), which limit a subject’s physical capabilities during operational scenarios. In this thesis, a general framework is proposed to find an easy way to measure the blood flow using thermal camera to help detecting cots and vascular diseases (Venous disease, Arterial disease). In this thesis, a general framework is proposed to use a thermal image based measurement technique for the volumetric flow rate of a liquid inside a thin tube. This technique makes use of the convection heat transfer dependency between the flow rate and the temperature of the flowing liquid along the tube. The proposed method can be applied to diagnose superficial venous disease non-invasively by measuring the volumetric blood flow rate from a FLIR LWIR single thermal image (Mahmoud et al., 13)

    MERS Coronavirus at the Human-Animal Interface

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    MERS Coronavirus at the Human-Animal Interface

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    Dissolution and drug release profiles of phosphate glasses doped with high valency oxides

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    This paper investigates phosphate glasses incorporating vanadium and molybdenum oxides for effective management of dissolution and drug release. These glass formulations are found to reduce the rate of dissolution from the glass surfaces. The drug functional groups of vancomycin molecules loaded by immersion showed stronger hydrogen bonding with Vanadium doped glasses and consequently lower rate of drug release over 2 weeks indicating better surface attachment with the drug molecules and slow drug release profiles. This can be explained by the strong adherence of drug molecules to glass surfaces compared with the molybdenum containing glasses (PM5 and PM10). The strong attachment relates to hydrogen bonding between the amino-functional groups of vancomycin and the hydrated P-O-H groups in the glass network. In conclusion, the rate of dissolution of doped glasses and the rate of drug release can be administered to deliver the drug molecules over weeks

    MERS Coronavirus at the Human-Animal Interface

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    Acaricidal efficiency of solar 50 % new emulsifiable concentrate formulation against the two-spotted spider mite (TSSM) Tetranychus urticae Koch (Acari: Tetranychidae) under laboratory and greenhouse conditions

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    Oils are some of the most efficient and secure alternatives to synthetic fungicides, acaricides and insecticides used as pesticides for decades. Around the world, mineral oils are a potential pesticide against many pests. To provide novel active ingredients and new pesticide formulations to the pesticide industry, the major goal of this research was to formulate one of the petroleum fractions and test its acaricidal efficiency against two-spotted spider mite (TSSM), Tetranychus urticae Koch (Acari: Tetranychidae). Solar's physical features were put to the test. Then, it was prepared as an emulsifiable concentrate following the guidelines provided by specialized pesticide organizations for this kind of formulation. The novel formulation was subsequently biologically tested against T. urticae adults in the lab, and it demonstrated good acaricidal activity with an LC50 of 4548 ppm. Under greenhouse conditions, it was also tested against T. urticae immature, adults (males and females) and number of deposited eggs. There was a direct correlation for all stages between concentration, the percentage of immature and adult mortality, and the percentage of egg-hatching inhibition. In the case of the immature, 100% mortality was shown after 7 days of treatment. However, in the case of adult males and females, 100% mortality was shown after 3 days of treatment. Additionally, after 14 days from treatment, it entirely stopped egg depositing. The new formulation might be applied to manage the TSSM.

    Palm oil formulation as 34 % mayonnaise and evaluation of its biological efficacy against citrus mealybug, Planococcus citri under laboratory and field conditions

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    The use of environmentally friendly pesticides using palm oil derivatives as palm oil methyl ester (PME) carrier solvents has been reported. PME-based glyphosate isopropylamine nanoemulsion in the water against weeds has been the subject of numerous studies as well as palm oil methyl ester molluscicidal against golden apple snails. This study's major goal was to formulate palm oil in an appropriate formulation form and assess its insecticidal effectiveness against citrus mealybug, Planococcus citri. Palm oil was formulated as 34% oil in water emulsion (O/W) (mayonnaise). The new mayonnaise formulation successfully passed all physical and chemical testing requirements set out by pesticide organizations for (O/W) emulsions. Under laboratory conditions, it was biologically evaluated against nymphs and adults of the citrus mealybug, Planococcus citri, with serial concentrations. It had considerable insecticidal activity against all study stages, although the impact on nymphs was significantly greater than that on adults. This was evident from its LC50 values, which were 53.52 and 58.58 mg/ml for nymphs and adults, respectively. The citrus mealybug, Planococcus citri, in its adult, nymphs, and gravid stages, was tested using the new palm oil 34% mayonnaise formulation in the field. The highest mortality percentages were seen in the nymphs, followed by adults and then the gravid stage. After additional research, the newly developed palm oil formula might be employed to combat the citrus mealybug, Planococcus citri

    Polyunsaturated fatty acids inhibit k<sub>v</sub>1.4 by interacting with positively charged extracellular pore residues

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    Polyunsaturated fatty acids (PUFAs) modulate voltage-gated K(+) channel inactivation by an unknown site and mechanism. The effects of ω-6 and ω-3 PUFAs were investigated on the heterologously expressed K(v)1.4 channel. PUFAs inhibited wild-type K(v)1.4 during repetitive pulsing as a result of slowing of recovery from inactivation. In a mutant K(v)1.4 channel lacking N-type inactivation, PUFAs reversibly enhanced C-type inactivation (K(d), 15–43 μM). C-type inactivation was affected by extracellular H(+) and K(+) as well as PUFAs and there was an interaction among the three: the effect of PUFAs was reversed during acidosis and abolished on raising K(+). Replacement of two positively charged residues in the extracellular pore (H508 and K532) abolished the effects of the PUFAs (and extracellular H(+) and K(+)) on C-type inactivation but had no effect on the lipoelectric modulation of voltage sensor activation, suggesting two separable interaction sites/mechanisms of action of PUFAs. Charge calculations suggest that the acidic head group of the PUFAs raises the pK(a) of H508 and this reduces the K(+) occupancy of the selectivity filter, stabilizing the C-type inactivated state
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