On Graphs Admitting Arc-Transitive Actions of Almost Simple Groups

AbstractLet Γ be a finite connected regular graph with vertex setVΓ, and letGbe a subgroup of its automorphism group AutΓ. Then Γ is said to beG-locally primitiveif, for each vertex α, the stabilizerGαis primitive on the set of vertices adjacent to α. In this paper we assume thatGis an almost simple group with socle socG=S; that is,Sis a nonabelian simple group andS⊴G≤AutS. We study nonbipartite graphs Γ which areG-locally primitive, such thatShas trivial centralizer in AutΓ andSis not semiregular on vertices. We prove that one of the following holds: (i)S⊴AutΓ≤Aut(S), (ii)G<Y≤AutΓ withYalmost simple and socY≠S, or (iii)Sbelongs to a very restricted family of Lie type simple groups of characteristicp, say, and AutΓ contains the semidirect productZdp:G, whereZdpis a known absolutely irreducibleG-module. Moreover, in certain circumstances we can guarantee thatS⊴AutΓ≤Aut(S). For example, if Γ is a connected (G,2)-arc transitive graph with Sz(q)≤G≤Aut(Sz(q)) (q=22n+1≥8) orG=Ree(q) (q=32n+1≥27), thenG≤AutΓ≤Aut(G)

A triclinic polymorph with Z = 3 of N,N′-bis­(2-pyrid­yl)oxamide

The asymmetric unit of the title compound, C12H10N4O2, contains three half-mol­ecules. Each half-mol­ecule is completed by crystallographic inversion symmetry. The title compound, (I), is a polymorph of the structure, (II), reported by Hsu & Chen [Eur. J. Inorg. Chem. (2004), 1488–1493]. In the original report, the compound crystallized in the tetra­gonal space group P 21c (Z = 8), whereas the structure reported here is triclinic (P , Z = 3). In both forms, each oxamide mol­ecule is almost planar (with maximum deviations are 0.266 and 0.166 Å) and the O atoms are trans oriented. The principal difference between the two forms lies in the different hydrogen-bonding patterns. In (I), two N—H⋯O and one N—H⋯N hydrogen bonds link the mol­ecules, forming a two-dimensional network, whereas in (II) there are no classical hydrogen bonds to O atoms and only weak C—H⋯O inter­actions are found along with rings of N—H⋯N bonds

5-Arc transitive cubic Cayley graphs on finite simple groups

AbstractIn this paper, we determine all connected 5-arc transitive cubic Cayley graphs on the alternating group A47; there are only two such graphs (up to isomorphism). By earlier work of the authors, these are the only two non-normal connected cubic arc-transitive Cayley graphs for finite nonabelian simple groups, and so this paper completes the classification of such non-normal Cayley graphs

Enhancement of polar phases in PVDF by forming PVDF/SiC nanowire composite

Different contents of silicon carbide (SiC) nanowires were mixed with Poly(vinylidene fluoride) (PVDF) to facilitate the polar phase crystallization. It was shown that the annealing temperature and SiC content affected on the phase and crystalline structures of PVDF/SiC samples. Furthermore, the addition of SiC nanowire enhanced the transformation of non-polar α phase to polar phases and increased the relative fraction of β phase in PVDF. Due to the nucleating agent mechanism of SiC nanowires, the ion-dipole interaction between the negatively charged surface of SiC nanowires and the positive CH2 groups in PVDF facilitated the formation of polar phases in PVDF

Improving mobility of silicon metal-oxide-semiconductor devices for quantum dots by high vacuum activation annealing

To improve mobility of fabricated silicon metal-oxide-semiconductor (MOS) quantum devices, forming gas annealing is a common method used to mitigate the effects of disorder at the Si/SiO2 interface. However, the importance of activation annealing is usually ignored. Here, we show that a high vacuum environment for implantation activation is beneficial for improving mobility compared to nitrogen atmosphere. Low-temperature transport measurements of Hall bars show that peak mobility can be improved by a factor of two, reaching 1.5 m^2/(Vs) using high vacuum annealing during implantation activation. Moreover, the charge stability diagram of a single quantum dot is mapped, with no visible disturbance caused by disorder, suggesting possibility of fabricating high-quality quantum dots on commercial wafers. Our results may provide valuable insights into device optimization in silicon-based quantum computing.Comment: 13 pages, 4 figure

利培酮合并舒眠胶囊治疗精神分裂症的疗效及对患者糖、脂代谢的影响

Objective: To explore the curative effect and influence on glucose and lipid metabolism of risperidone with Shu Mian capsules in patients with schizophrenia .Methods: 128patients with chronic schizophrenia were randomly divided into the combined group (crisperidone combined with shu mian capsules group) and the single group (risperidone group ), each group was assessed the positive and negative syndrome scale (PANSS),the body mass index (BMI ) was measured and the blood glucose and blood lipid were detected before treatment and after 2,4,8 weekends respectively. After 4,8 weeks ,both the two groups were assessed by Wesconsin card sorting test ( WCST) curative effect and their cognitive function was evaluated .Results: The reacting time in the two groups were of no significantly difference , but compared with condition before treatment, cognitive function of the patients with schizophrenia was improved and their level of total cholesterol was significantly increased (P &lt; 0.05) in the combined group. BMI, blood glucose and blood lipid were significantly increased in single group after 8weeks’ treatment (P &lt; 0.05 or P &lt; 0.01). Conclusion: Shu Mian capsules can lower negative symptoms and improve cognitive function of schizophrenia ,and the dverse reactions is mild. With therapeutic dose range, risperidone in combined group or single group can make equal reacting time, curative effect and affecting blood lipid metabolism in patients with schizophrenia. Single group shows more obvious influence on blood sugat and blood fat metabolismcan.目的  探讨利培酮合并舒眠胶囊治疗慢性精神分裂症的疗效及对患者糖、脂代谢的影响。方法  128例精神分裂症患者采用系统随机分为联合组（利培酮合并舒眠胶囊组）和单用组（利培酮组）。每组各64例分别于治疗前及治疗2、4、8周末采用阳性与阴性症状量表（PANSS）进行评分，并检测体质量指数（BMI）、血糖及血脂；4、8周末评价认知能力及疗效。结果  联合组和单用组起效时间比较差异无统计学意义；联合组能部分改善精神分裂症患者的认知能力，与治疗前相比8周未联合组总胆固醇明显增高（P＜0.05）；单用组BMI、血糖、总胆固醇和甘油三酯明显增高（P＜0.05 或P＜0.01）。结论  舒眠胶囊对精神分裂症阴性症状和认知功能有一定改善作用，不良反应轻微。利培酮治疗精神分裂症的剂量范围内联合组和单用组起效时间相当，但均可影响脂代谢；单用组对血糖、血脂代谢的影响更明显。 

AVE0991, a Nonpeptide Compound, Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation via Induction of Heme Oxygenase-1 and Downregulation of p-38 MAPK Phosphorylation

The nonpeptide AVE0991 is an agonist of the angiotensin-(1–7) (Ang-(1–7)) Mas receptor and is expected to be a putative new drug for treatment of cardiovascular disease. However, the mechanisms involved in the antiproliferative effects of AVE0991 are not fully understood. We saw that the compound attenuated proliferation in an angiotensin II-induced rat vascular smooth muscle cells (VSMC) proliferation model. Moreover, treatment with AVE0991 (10−5 mol/L or 10−7 mol/L) significantly attenuated reactive oxygen species (ROS) production, phosphorylation of p38 MAPK, and dose-dependently (10−8 to 10−5 mol/L) inhibited Ang II-induced VSMC proliferation. Meanwhile, heme oxygenase-1 (HO-1) expression increased in the AVE0991 + Ang II group (10−5 mol/L or 10−6 mol/L). However, the beneficial effects of AVE0991 were completely abolished when the VSMC were pretreated with A-779 (10−6 mol/L). Furthermore, treatment with the HO-1 inhibitor ZnPPIX attenuated the inhibitory effect of AVE0991 on Ang II-induced p38MAPK phosphorylation. These results suggest that AVE0991 attenuates Ang II-induced VSMC proliferation in a dose-dependent fashion and that this effect is associated with the Mas/HO-1/p38 MAPK signaling pathway

A new polymorph of magnesium oxalate dihydrate

In the asymmetric unit of the title compound, catena-poly[[diaqua­magnesium(II)]-μ-oxalato], [Mg(C2O4)(H2O)2]n, there is one Mg atom in an octa­hedral coordination with site symmetry 222, a unique C atom of the oxalate anion lying on a twofold axis, an O atom of the anion in a general position and a water O atom at a site with imposed twofold rotation symmetry. The Mg2+ ions are ligated by water mol­ecules and bridged by the anions to form chains that are held together by O—H⋯O hydrogen bonds. The structure of the title compound has already been reported in a different space group [Lagier, Pezerat & Dubernat (1969 ▶). Rev. Chim. Miner. 6, 1081–1093; Levy, Perrotey & Visser (1971 ▶). Bull. Soc. Chim. Fr. pp. 757–761]