Inhibition of nitrogenase by oxygen in marine cyanobacteria controls the global nitrogen and oxygen cycles

International audienceCyanobacterial N2-fixation supplies the vast majority of biologically accessible inorganic nitrogen to nutrient-poor aquatic ecosystems. The process, catalyzed by the heterodimeric protein complex, nitrogenase, is thought to predate that of oxygenic photosynthesis. Remarkably, while the enzyme plays such a critical role in Earth's biogeochemical cycles, the activity of nitrogenase in cyanobacteria is markedly inhibited in vivo at a post-translational level by the concentration of O2 in the contemporary atmosphere leading to metabolic and biogeochemical inefficiency in N2 fixation. We illustrate this crippling effect with data from Trichodesmium spp. an important contributor of "new nitrogen" to the world's subtropical and tropical oceans. The enzymatic inefficiency of nitrogenase imposes a major elemental taxation on diazotrophic cyanobacteria both in the costs of protein synthesis and for scarce trace elements, such as iron. This restriction has, in turn, led to a global limitation of fixed nitrogen in the contemporary oceans and provides a strong biological control on the upper bound of oxygen concentration in Earth's atmosphere

Holography, Pade Approximants and Deconstruction

We investigate the relation between holographic calculations in 5D and the Migdal approach to correlation functions in large N theories. The latter employs Pade approximation to extrapolate short distance correlation functions to large distances. We make the Migdal/5D relation more precise by quantifying the correspondence between Pade approximation and the background and boundary conditions in 5D. We also establish a connection between the Migdal approach and the models of deconstructed dimensions.Comment: 28 page

Neutron-Electron EDM Correlations in Supersymmetry and Prospects for EDM Searches

Motivated by recent progress in experimental techniques of electric dipole moment (EDM) measurements, we study correlations between the neutron and electron EDMs in common supersymmetric models. These include minimal supergravity (mSUGRA) with small CP phases, mSUGRA with a heavy SUSY spectrum, the decoupling scenario and split SUSY. In most cases, the electron and neutron EDMs are found to be observable in the next round of EDM experiments. They exhibit certain correlation patterns. For example, if d_n ~ 10^{-27} e cm is found, d_e is predicted to lie in the range 10^{-28}-10^{-29} e cm.Comment: 16 pages,12 figures. To appear in JHEP. A note on stability of the correlations added in Conclusions; refs. and footnotes adde

Moduli stabilization with positive vacuum energy

We study the effect of anomalous U(1) gauge groups in string theory compactification with fluxes. We find that, in a gauge invariant formulation, consistent AdS vacua appear breaking spontaneously supergravity. Non vanishing D-terms from the anomalous symmetry act as an uplifting potential and could allow for de Sitter vacua. However, we show that in this case the gravitino is generically (but not always) much heavier than the electroweak scale. We show that alternative uplifting scheme based on corrections to the Kahler potential can be compatible with a gravitino mass in the TeV range.Comment: 20 pages, 1 figur

Supersymmetric Boundaries and Junctions in Four Dimensions

We make a comprehensive study of (rigid) N=1 supersymmetric sigma-models with general K\"ahler potentials K and superpotentials w on four-dimensional space-times with boundaries. We determine the minimal (non-supersymmetric) boundary terms one must add to the standard bulk action to make it off-shell invariant under half the supersymmetries without imposing any boundary conditions. Susy boundary conditions do arise from the variational principle when studying the dynamics. Upon including an additional boundary action that depends on an arbitrary real boundary potential B one can generate very general susy boundary conditions. We show that for any set of susy boundary conditions that define a Lagrangian submanifold of the K\"ahler manifold, an appropriate boundary potential B can be found. Thus the non-linear sigma-model on a manifold with boundary is characterised by the tripel (K,B,w). We also discuss the susy coupling to new boundary superfields and generalize our results to supersymmetric junctions between completely different susy sigma-models, living on adjacent domains and interacting through a "permeable" wall. We obtain the supersymmetric matching conditions that allow us to couple models with different K\"ahler potentials and superpotentials on each side of the wall.Comment: 38 pages, 1 figur

Interesting consequences of brane cosmology

We discuss cosmology in four dimensions within a context of brane-world scenario.Such models can predict chaotic inflation with very low reheat temperature depending on the brane tension. We notice that the gravitino abundance is different in the brane-world cosmology and by tuning the brane tension it is possible to get extremely low abundance. We also study Affleck-Dine baryogenesis in our toy model.Comment: 5 pages, Trivial changes to match the published versio

Molecular bases and photobiological consequences of light intensity adaptation in photosynthetic organisms

By applying a combination of light transitions, uncouplers, and inhibitors of photosynthetic electron transport inhibitors we modulate the redox poise of many components in the plastid and examine the pattern of expression of cab1 gene. This gene encodes the major light harvesting protein that services photosystem II. While our results have confirmed our own previous finding that light intensity regulation of cab1 gene expression is signaled by the redox state of the PQ pool, we have also identified additional sensor(s) located in the PET chain