An approximation scheme for an Eikonal Equation with discontinuous coefficient

We consider the stationary Hamilton-Jacobi equation where the dynamics can vanish at some points, the cost function is strictly positive and is allowed to be discontinuous. More precisely, we consider special class of discontinuities for which the notion of viscosity solution is well-suited. We propose a semi-Lagrangian scheme for the numerical approximation of the viscosity solution in the sense of Ishii and we study its properties. We also prove an a-priori error estimate for the scheme in an integral norm. The last section contains some applications to control and image processing problems

Verifying Policy Enforcers

Policy enforcers are sophisticated runtime components that can prevent failures by enforcing the correct behavior of the software. While a single enforcer can be easily designed focusing only on the behavior of the application that must be monitored, the effect of multiple enforcers that enforce different policies might be hard to predict. So far, mechanisms to resolve interferences between enforcers have been based on priority mechanisms and heuristics. Although these methods provide a mechanism to take decisions when multiple enforcers try to affect the execution at a same time, they do not guarantee the lack of interference on the global behavior of the system. In this paper we present a verification strategy that can be exploited to discover interferences between sets of enforcers and thus safely identify a-priori the enforcers that can co-exist at run-time. In our evaluation, we experimented our verification method with several policy enforcers for Android and discovered some incompatibilities.Comment: Oliviero Riganelli, Daniela Micucci, Leonardo Mariani, and Yli\`es Falcone. Verifying Policy Enforcers. Proceedings of 17th International Conference on Runtime Verification (RV), 2017. (to appear

Fermion masses and mixings in gauge theories

The recent evidence for neutrino oscillations stimulate us to discuss again the problem of fermion masses and mixings in gauge theories. In the standard model, several forms for quark mass matrices are equivalent. They become ansatze within most extensions of the standard model, where also relations between quark and lepton sectors may hold. In a seesaw framework, these relations can constrain the scale of heavy neutrino mass, which is often related to the scale of intermediate or unification gauge symmetry. As a consequence, two main scenarios arise. Hierarchies of masses and mixings may be explained by broken horizontal symmetries.Comment: 25 pages, RevTex, no figures. Few misprints corrected and two references adde

Use of the KlADH4 promoter for ethanol-dependent production of recombinant human serum albumine in Kluyveromyces lactis

KlADH4 is a gene of Kluyveromyces lactis encoding a mitochondrial alcohol dehydrogenase activity which is specifically induced by ethanol. The promoter of this gene was used for the expression of heterologous proteins in K. lactis, a very promising organism which can be used as an alternative host to Saccharomyces cerevisiae due to its good secretory properties. In this paper we report the ethanol-driven expression in K. lactis of the bacterial beta-glucuronidase and of the human serum albumin (HSA) genes under the control of the KlADH4 promoter. In particular, we studied the extracellular production of recombinant HSA (rHSA) with integrative and replicative vectors and obtained a significant increase in the amount of the protein with multicopy vectors, showing that no limitation of KlADH4 trans-acting factors occurred in the cells. By deletion analysis of the promoter, we identified an element (UASE) which is sufficient for the induction of KlADH4 by ethanol and, when inserted in the respective promoters, allows ethanol-dependent activation of other yeast genes, such as PGK and LAC4. We also analyzed the effect of medium composition on cell growth and protein secretion. A clear improvement in the production of the recombinant protein was achieved by shifting from batch cultures (0.3 g/liter) to fed-batch cultures (1 g/liter) with ethanol as the preferred carbon source

Leptogenesis and Low-energy Observables

We relate leptogenesis in a class of theories to low-energy experimental observables: quark and lepton masses and mixings. With reasonable assumptions motivated by grand unification, one can show that the CP-asymmetry parameter takes a universal form. Furthermore the dilution mass is related to the light neutrino masses. Overall, these models offer a natural explanation for a lepton asymmetry in the early universe.Comment: 10 pages, revised discussion on light neutrino masse

Aplicación del Método Acelerado CAMBT para evaluar la reactividad alcalina de agregados

Para evaluar la reactividad alcalina de los agregados, en Argentina se aplican el análisis petrográfico (IRAM 1649 / ASTM C295), el acelerado de la barra de mortero (IRAM 1674 / ASTM C1260) y el del prisma de hormigón (IRAM 1700 / ASTM C1293). Dado que en algunos casos los resultados de métodos diferentes no concordaban entre sí, se recurrió a un método de ensayo acelerado, de origen chino (CAMBT). Conceptualmente se asemeja al método ASTM C1260 con diferencias en la granulometría y en las proporciones de los agregados, el tipo de cemento y el tamaño de las probetas. El estacionamiento se realiza en NaOH 1N a 80ºC y el límite de aceptación máximo para la expansión es de 0,093% a 16 días. Se muestran los resultados de 6 agregados, tres granitos, una sienita cuarcífera, una ortocuarcita y un basalto. Los resultados obtenidos son congruentes con las diferentes mineralogías y los estudios previos o el comportamiento en obras de hormigón existentes que utilizaron algunos de estos agregados.In order to evaluate the alkaline reactivity of aggregates, in Argentina are applied the petrographic analysis (IRAM 1649 / ASTM C295), accelerated mortar bar test (IRAM 1674 / ASTM C1260) and concrete prism test (IRAM 1700 / ASTM C1293 .) Since in some cases the results of different methods did not agree with each other, a Chinese accelerated mortar bar test (CAMBT) was tested. Conceptually it is similar to ASTM C1260 with differences in the granulometry and proportions of aggregates, cement type and specimens size. The storage is done in 1N NaOH at 80°C and the maximum limit of acceptance for the expansion is 0.093% at 16 days. The results of six aggregates, three granites, a quartz syenite, an ortoquartzite and a basalt are shown. The obtained results are consistent with the different mineralogies and previous studies, or its behaviour in several concrete structures made by using some of this aggregates

Matrix sketching for supervised classification with imbalanced classes

The presence of imbalanced classes is more and more common in practical applications and it is known to heavily compromise the learning process. In this paper we propose a new method aimed at addressing this issue in binary supervised classification. Re-balancing the class sizes has turned out to be a fruitful strategy to overcome this problem. Our proposal performs re-balancing through matrix sketching. Matrix sketching is a recently developed data compression technique that is characterized by the property of preserving most of the linear information that is present in the data. Such property is guaranteed by the Johnson-Lindenstrauss’ Lemma (1984) and allows to embed an n-dimensional space into a reduced one without distorting, within an ϵ-size interval, the distances between any pair of points. We propose to use matrix sketching as an alternative to the standard re-balancing strategies that are based on random under-sampling the majority class or random over-sampling the minority one. We assess the properties of our method when combined with linear discriminant analysis (LDA), classification trees (C4.5) and Support Vector Machines (SVM) on simulated and real data. Results show that sketching can represent a sound alternative to the most widely used rebalancing methods

Fully-automated Runtime Enforcement of Component-based Systems with Formal and Sound Recovery

International audienceWe introduce runtime enforcement of specifications on component-based systems (CBS) modeled in the BIP (Behavior, Interaction and Priority) framework. Runtime enforcement is an increasingly popular and effective dynamic validation technique aiming to ensure the correct runtime behavior (w.r.t. a formal specification) of a system using a so-called enforcement monitor. BIP is a powerful and expressive component-based framework for the formal construction of heterogeneous systems. Because of BIP expressiveness however , it is difficult to enforce complex behavioral properties at design-time. We first introduce a theoretical runtime enforcement framework for component-based systems where we delineate a hierarchy of enforceable properties (i.e., properties that can be enforced) according to the number of observational steps a system is allowed to deviate from the property (i.e., the notion of k-step enforceability). To ensure the observational equivalence between the correct executions of the initial system and the monitored system, we show that i) only stutter-invariant properties should be enforced on CBS with our monitors, and ii) safety properties are 1-step enforceable. Second, given an abstract enforcement monitor for some 1-step enforceable property, we define a series of formal transformations to instrument (at relevant locations) a CBS described in the BIP framework to integrate the monitor. At runtime, the monitor observes and automatically avoids any error in the behavior of the system w.r.t. the property. Third, our approach is fully implemented in RE-BIP, an available tool integrated in the BIP tool suite. Fourth, to validate our approach, we use RE-BIP to i) enforce deadlock-freedom on a dining philosophers benchmark, and ii) ensure the correct placement of robots on a map