Production of Dispersion Alloys with the Aid of Ultrasonics Final Report

Dispersion of inerts in molten matrix by ultrasonic energy, and ultrasonic treatment of alloys to produce dispersion strengthenin

Book Review: Space and Time Perspective in Northern St. Johns Archeology, Florida

A review of Goggin, John M.: Space and Time Perspective in Northern St. Johns Archeology, Florida Yale University Publications in Anthropology, No. 47, Yale University Press, New Haven. 1952. (147 pp., 12 plates, 8 text figures, one map, $2.00

IL-12 and IL-4 activate a CD39-dependent intrinsic peripheral tolerance mechanism in CD8+ T cells

Immune responses to protein antigens involve CD4+ and CD8+ T cells, which follow distinct programs of differentiation. Naïve CD8 T cells rapidly develop cytotoxic T-cell (CTL) activity after T-cell receptor stimulation, and we have previously shown that this is accompanied by suppressive activity in the presence of specific cytokines, i.e. IL-12 and IL-4. Cytokine-induced CD8+ regulatory T (Treg) cells are one of several Treg-cell phenotypes and are Foxp3− IL-10+ with contact-dependent suppressive capacity. Here, we show they also express high level CD39, an ecto-nucleotidase that degrades extracellular ATP, and this contributes to their suppressive activity. CD39 expression was found to be upregulated on CD8+ T cells during peripheral tolerance induction in vivo, accompanied by release of IL-12 and IL-10. CD39 was also upregulated during respiratory tolerance induction to inhaled allergen and on tumor-infiltrating CD8+ T cells. Production of IL-10 and expression of CD39 by CD8+ T cells was independently regulated, being respectively blocked by extracellular ATP and enhanced by an A2A adenosine receptor agonist. Our results suggest that any CTL can develop suppressive activity when exposed to specific cytokines in the absence of alarmins. Thus negative feedback controls CTL expansion under regulation from both nucleotide and cytokine environment within tissues

Comet and close-approach asteroid mission study. volume 1- summary report final report

Comet and close-approach asteroid mission stud

Trends in fire patterns in a southern African savanna under alternative land use practices

Climate, topography, vegetation and land use interact to influence fire regimes. Variable fire regimes may promote landscape heterogeneity, diversification in vegetation pattern and biotic diversity. The objective was to compare effects of alternative land use practices on landscape heterogeneity. Patch characteristics of fire scars were measured from 21 annual burn maps produced from 1972 to 2001 Landsat imagery. Trends in fire patterns under alternative land use practices were compared across a 250,000 ha savanna in southern Africa partitioned into three land use zones. Zone 1, Madikwe Game Reserve (MGR), has had mostly prescribed fires since 1993. Zone 2, cattle farms near MGR in South Africa (SAF), has experienced occasional fires. Zone 3, communal grazing lands in neighboring Botswana (BOT), has had the fewest fires. Cattle ranching was the predominant land use throughout the study area until 1992, when land use switched to conservation and eco-tourism in MGR. Sixteen landscape metrics were applied to this data set to uncover trends in the patch characteristics of the fire scars. A principal components analysis (PCA) reduced the dimensionality of the results so trends in the 10 most important size, shape, and proximity metrics could be better interpreted. The PCA results showed that more burning over time in MGR, and to a lesser extent in SAF, increased patch size, size variability, shape complexity and proximity, while fire exclusion in BOT produced no change or decreasing trends. We tested for significant differences in these metrics between the three land use zones and between two periods, 1972–1992 and 1993–2001. Most patch characteristics in MGR and SAF differed significantly from those in BOT, especially during the latter period, while between MGR and SAF they did not. Patch area, shape complexity and core area increased significantly between periods in MGR, while patch size, size variability and core area increased significantly between periods in SAF. In BOT, no patch characteristics changed significantly between periods. Within the time span analyzed for the study area, we conclude that increased fire occurrence promoted landscape heterogeneity while fire exclusion did not

Effects of Wing and Nacelle Modifications on Drag and Wake Characteristics of a Bomber-Type Airplane Model

An investigation of a model of a large four-engine bomber was conducted in the Langley 19-f'oot pressure tunnel to determine the effects of several wing and nacelle modifications on drag characteristics and air flow characteristics at the tail. Leading-edge gloves, trailing-edge extensions, and modified nacelle afterbodies were tested individual ly and in combination. The effects of the various modifications were determined by force tests, tuft observations, and turbulence s1ITveys in the region of the tail. Tests were made with fixed and natural transition on the wing and with propellers operating and propellers off. Most of the tests were con- ducted at a Reynolds number of approximately 2.6 x 106. The results indicated that application of certain of the modifications provided worth-while improvements in the characteristics or the model. The flow over the wing and flaps was improved, the drag was reduced, and the turbulence in the region of the tail was reduced. Trailing-edge extensions were the most effective individual modification in improving the flow over the wing with wing flaps neutral, cowl and intercooler flaps clos ed. Modified nacelle afterbodies were the most effectiv8 individual edification in reducing drag with either fixed or natural transition on the wing; however, trailin6-edge extensions were slightly more effective with fixed transition. Combinations of either leading or trailing-edge extensions and modified afterbodies were more effective than either modification alone. With cowl and intercooler flaps open, trailing-edge extensions with modified afterbodies provided substantial improvement in flow and drag characteristics. With wing flaps deflected, enclosing the flap behind the inboard nacelle within an extended afterbody or cutting the flaps at the nacelle appeared. to be the most promising methods of improving the f low over the flaps and the tail. Although the results of hot-wire-anenometer surveys were not conclusive in regard to buffeting characteristics, the modifications did educe the turbulence at the tail with wing flaps both neutral and deflected. The modifications, as a rule, were favorable to maximum lift. Appreciable reductions in longitudinal stability of the model were caused by addition of leading -edge gloves and tr ailing -edge extensions

Common and Differential Factors in Reading Vocabulary and Hearing Vocabulary

Numerous studies have shown that recognition of word meaning is closely related to reading ability. All of these studies, however, measured reading vocabulary only. This research attempts to determine how recognition of read and heard words compares, and how the two types of vocabulary are related to reading ability. Since material is held constant, but the mode of presentation is varied, this approach should make possible the study of certain common and specific elements in the abilities to recognize words read and heard, and to determine the manner in which this relationship is affected by reading ability

Relative effects of mammal herbivory and plant spacing on seedling recruitment following fire and mining

<p>Abstract</p> <p>Background</p> <p>There is much debate concerning which ecological constraints are the most limiting factors to seedling recruitment in disturbed communities. We provide the first comparison between selective herbivory and plant competition effects among two post-mined forest ecosystems (primary succession) and one post-fire woodland ecosystem (secondary succession). Animal exclosure assessments of nine common species across eight sites were performed for comparison within three locations separated by up to 200 km. Additionally, we asked whether pre-browsed plants differed in nutrient content between or within species in the separate systems.</p> <p>Results</p> <p>Among the nine common species, seven of these were affected by mammal herbivory while five shared a similar vulnerability to predation regardless of system. One species was limited by competition (planting density). There was a strong linear correlation between herbivore selectivity (% browsed) and impact (biomass loss) on the fertilized minesites, but not post-fire sites. Phosphorus and potassium were higher for most species in the post-mined system. Principal components analyses revealed that nutrients in shortest supply may be the most likely components of selection within each system. Among all locations, species with highest levels of phosphorus, ADF and leaf water content were often favoured, while high tannins and nitrogen content were generally selected against.</p> <p>Conclusion</p> <p>Herbivory, rather than seedling competition, was the limiting factor for plant performance among post-fire and post-mined reclamation areas. The post-fire seedlings were smaller and more water and nutrient limited, nevertheless browsing prevalence was equivalent at all locations with nearly all seedlings predated. Kangaroo density in the post-fire community declined from the beginning of the experiment, while numbers in the post-mined revegetation increased fourfold within one year. Differences in water and nutrient availability may explain why herbivores are more likely to be attracted to post-mined communities.</p