313 research outputs found
Surface electromyographic control of a novel phonemic interface for speech synthesis
Many individuals with minimal movement capabilities use AAC to communicate. These individuals require both an interface with which to construct a message (e.g., a grid of letters) and an input modality with which to select targets. This study evaluated the interaction of two such systems: (a) an input modality using surface electromyography (sEMG) of spared facial musculature, and (b) an onscreen interface from which users select phonemic targets. These systems were evaluated in two experiments: (a) participants without motor impairments used the systems during a series of eight training sessions, and (b) one individual who uses AAC used the systems for two sessions. Both the phonemic interface and the electromyographic cursor show promise for future AAC applications.F31 DC014872 - NIDCD NIH HHS; R01 DC002852 - NIDCD NIH HHS; R01 DC007683 - NIDCD NIH HHS; T90 DA032484 - NIDA NIH HHShttps://www.ncbi.nlm.nih.gov/pubmed/?term=Surface+electromyographic+control+of+a+novel+phonemic+interface+for+speech+synthesishttps://www.ncbi.nlm.nih.gov/pubmed/?term=Surface+electromyographic+control+of+a+novel+phonemic+interface+for+speech+synthesisPublished versio
The COPI Complex Functions in Nuclear Envelope Breakdown and Is Recruited by the Nucleoporin Nup153
AbstractNuclear envelope breakdown is a critical step in the cell cycle of higher eukaryotes. Although integral membrane proteins associated with the nuclear membrane have been observed to disperse into the endoplasmic reticulum at mitosis, the mechanisms involved in this reorganization remain to be fully elucidated. Here, using Xenopus extracts, we report a role for the COPI coatomer complex in nuclear envelope breakdown, implicating vesiculation as an important step. We have found that a nuclear pore protein, Nup153, plays a critical role in directing COPI to the nuclear membrane at mitosis and that this event provides feedback to other aspects of nuclear disassembly. These results provide insight into how key steps in nuclear division are orchestrated
Statistics in Focus. Economy and finance. EU-15 and EUR-11 current [trade] surplus: new growth in 1996. 1999.7
Ability-Based Methods for Personalized Keyboard Generation
This study introduces an ability-based method for personalized keyboard
generation, wherein an individual's own movement and human-computer interaction
data are used to automatically compute a personalized virtual keyboard layout.
Our approach integrates a multidirectional point-select task to characterize
cursor control over time, distance, and direction. The characterization is
automatically employed to develop a computationally efficient keyboard layout
that prioritizes each user's movement abilities through capturing directional
constraints and preferences. We evaluated our approach in a study involving 16
participants using inertial sensing and facial electromyography as an access
method, resulting in significantly increased communication rates using the
personalized keyboard (52.0 bits/min) when compared to a generically optimized
keyboard (47.9 bits/min). Our results demonstrate the ability to effectively
characterize an individual's movement abilities to design a personalized
keyboard for improved communication. This work underscores the importance of
integrating a user's motor abilities when designing virtual interfaces.Comment: 20 pages, 7 figure
Moisture susceptibility of high and low compaction dry process crumb rubber modified asphalt mixtures
The field performance of dry process crumb rubber-modified (CRM) asphalt mixtures has been reported to be inconsistent with stripping and premature cracking on the surfacing. One of the concerns is that, because achieving field compaction of CRM material is difficult due to the inherent resilient nature of the rubber particle, nonuniform field compaction may lead to a deficient bond between rubber and bitumen. To assess the influence of compaction, a series of CRM and control mixtures was produced and compacted at two levels: 4% (low, optimum laboratory compaction) and 8% (high, field experience) air void content. The long-term durability, in regard to moisture susceptibility of the mixtures, was assessed by conducting repeated moisture conditioning cycles. Mechanical properties (stiffness, fatigue, and resistance to permanent deformation) were determined in the Nottingham Asphalt Tester. Results indicated that compared with conventional mixtures, the CRM mixtures, regardless of compaction effort, are more susceptible to moisture with the degree of susceptibility primarily depending on the amount of rubber in the mixture, rather than the difference in compaction. This behavior is different from that of conventional mixtures in which, as expected, poorly compacted mixtures were found to be more susceptible to moisture than were well-compacted mixtures
Research Space at Public R1 Universities in the Mountain West, 2021
This fact sheet reports data on research space square footage for public R1 universities in five Mountain West States: Arizona, Colorado, Nevada, New Mexico, and Utah. This fact sheet includes national rankings of public R1 universities in the Mountain West states based on total square footage and reports square footage for individual research disciplines for the two public R1 universities in Nevada: the University of Nevada, Las Vegas (UNLV) and the University of Nevada, Reno (UNR)
Educational Attainment in the Mountain West, 2021
This fact sheet examines data on educational attainment rates for five states in the Mountain West: Arizona, Colorado,Nevada, New Mexico, and Utah. The original report from the Lumina Foundation explores education attainment data for those aged 25 to 64 years in all U.S. states
The State of Mental Health in the Mountain West, 2023
This fact sheet examines the state of mental health for both youth and adults and availability of mental health care in the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. The data are retrieved from Mental Health America’s (MHA) 2023 report, The State of Mental Health in America
Novel hard, tough HfAlSiN multilayers, defined by alternating Si bond structure, deposited using modulated high-flux, low-energy ion irradiation of the growing film
- …