Hepatoprotective effect of Descurainia sophia seed extract against paracetamol-induced oxidative stress and hepatic damage in mice

Introduction: In this study, we aimed to evaluate the protective effects of Descurainia sophia seed extract on paracetamol-induced oxidative stress and acute liver injury in mice. Methods: Sixty male Swiss albino mice were divided into 6 groups, group I: as control group received NaCl 9%. Group II: as paracetamol group received paracetamol intraperitoneally (i.p.) (500 mg/kg). Groups III to VI as treatment groups received different doses of D. sophia seed extract (T1 = 50, T2 = 100, T3 = 200 and T4 = 300 mg/kg, respectively). Twenty-four hours after the paracetamol administration, the mice were sacrificed under mild anesthesia and their blood samples were collected to estimate serum alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin and malondialdehyde (MDA) levels. Their livers were also removed for histopathological examinations. Results: Pretreatment of mice with D. sophia seed extract, significantly prevented the paracetamol induced elevation in the levels of serum ALT, AST and ALP, total bilirubin and MDA (P < 0.05). The results of histopathologic studies were consistent with the above findings. Conclusion: Descurainia sophia seed extract has a protective effect against paracetamol induced oxidative damage and acute hepatotoxicity in mice

An Intelligent Customer Relationship Management (I-CRM) Framework and its Analytical Approaches to the Logistics Industry

This thesis develops a new Intelligent Customer Relationship Management (i-CRM) framework, incorporating an i-CRM analytical methodology including text-mining, type mapping, liner, non-liner and neuron-fuzzy approaches to handle customer complaints, identify key customers in the context of business values, define problem significance and issues impact factors, coupled with i-CRM recommendations to help organizations to achieve customer satisfaction through transformation of the customer complaints to organizational opportunities and business development strategies

The efficient bond among mobile commerce, CRM and E-loyalty to maximise the productivity of companies

Mobile commerce, has become a significant topic in IS research community and it is a key concept for many businesses, However, it has not fulfilled the expectations. This paper tackles the issue of mobile commerce in three different ways. First, it emphasizes the relative importance of customer relationship management and its relationship with mobile commerce. Second, it illustrates the ways to enhance E-loyalty of the clients within small and medium enterprises. Ultimately, the positive relationship among these, three concepts will be clarified. M-Commerce constitutes an important future market worldwide.This paper argues that businesses should strengthen and enhance loyalty as well as e-loyalty and M-Commerce activities, in order to better acquire the customers toward wireless marketing and customer relationship channels. Moreover to get the most euphoria businesses must create value for consumers in a way that is different from what they get used to prior to the latest version of services from the businesses. This paper, introduces a new area of doing business with the assistance of CRM and some evaluators to grasp loyalty under the context of mobile commerce. In addition, businesses should consider consumer's willingness to use successful features of M-Commerce. While performing the project, we expect to achieve productivity and reputation to the organization

Intelligent CRM on the cloud

This paper presents a new conceptual framework and practical solution for Customer Relationship Management(CRM) and E-Loyalty programs for cutting edge M-Commerce. CRM has come to the world of technology to help companies maximise technology usage. CRM means disciplined business strategy to create and sustain long-term, profitable customer relationships. To this aim, it must concentrate on customer. This paper introduces the notion of Intelligence CRM (i-CRM), and will define and develop i-CRM, E-Loyalty for the M-Commerce environment including Cloud services. The conceptual framework will include solutions for customer complaints and evaluation of the solution through perceived value, interactivity, and acceptance of i-CRM, perceived ease of use, perceived usefulness, loyalty and E-Loyalty. This paper shows how i-CRMcan foresee the threshold of customer feedback creating an innovative solution to minimize negative customer feedback and increase the loyalty and E-Loyalty of an organization

The Critical Success Factors for Implementation of CRM and Knowledge Management in a Work Setting

Customer Relationship Management is the most vigorous tools in our era and is the integration of trust, business and technology to gratify the requirements of the clients. CRM is a strategy of dealing with people, technology and process and need to be implemented precisely. CRM is the most outstanding business strategy that consolidates internal procedures and externals to generate and convey value to the spotted customers and CRM can easily neutralize competitive perils, provide a good source of roadmap for the company and customers. Moreover it may clarify the potential pitfalls in creating success for the company.CRM involves validating and evaluating critical success factors, which cover the three perspectives of CRM as the theoretical base, and which constitute a guide for companies in the implementation of the applications. Due to this, the desired benefits have intensified customer satisfaction and maintenance, by generating personalized products and value-added services. In this paper, the author investigates the factors that can positively leverage the implementation and use of CRM and creates differentiation among these factors and knowledge management factors. What is more, the paper aims at determining technical feature between CRM and knowledge management and managed to compare KM with CRM successfully

RESUMO DAS DISSERTAÇÕES DEFENDIDAS NO PROGRAMA DE PÓS-GRADUAÇÃO EM EDUCAÇÃO JULHO A DEZEMBRO DE 2018

RESUMO DAS DISSERTAÇÕES DEFENDIDAS NO PROGRAMA DE PÓS-GRADUAÇÃO EM EDUCAÇÃO JULHO A DEZEMBRO DE 2018

REGULAMENTO DO LABORATÓRIO DE POLÍTICA, AVALIAÇÃO E GESTÃO DA EDUCAÇÃO - LAPAGE

ANEXO À RESOLUÇÃO N. 231/2010 DO CONSELHO DIRETOR DA FACULDADE DE EDUCAÇÃ