217 research outputs found
Muslim Girls in Belgium Individual Freedom through Religion?
Research on Muslim communities in Europe has recently shifted focus from labor and social policy concerns to issues of 'religion' and 'culture'. In particular, there has been a growing interest in the possible emergence of a specifically 'European Islam'. Through examining the religious attitudes and practices of Muslim girls in Belgium, the author investigates the viability of a 'European Islam' and in so doing poses questions about the nature of secularization, free will and individualization of religious practice and belief
Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasis
The extracellular calcium (Ca(2+)(o))-sensing receptor (CaSR) is a family C G protein-coupled receptor, which detects alterations in Ca(2+)(o) concentrations and modulates parathyroid hormone secretion and urinary calcium excretion. The central role of the CaSR in Ca(2+)(o) homeostasis has been highlighted by the identification of mutations affecting the CASR gene on chromosome 3q21.1. Loss-of-function CASR mutations cause familial hypocalciuric hypercalcaemia (FHH), whereas gain-of-function mutations lead to autosomal dominant hypocalcaemia (ADH). However, CASR mutations are only detected in â€70% of FHH and ADH cases, referred to as FHH type 1 and ADH type 1, respectively, and studies in other FHH and ADH kindreds have revealed these disorders to be genetically heterogeneous. Thus, loss- and gain-of-function mutations of the GNA11 gene on chromosome 19p13.3, which encodes the G-protein α-11 (Gα(11)) subunit, lead to FHH type 2 and ADH type 2, respectively; whilst loss-of-function mutations of AP2S1 on chromosome 19q13.3, which encodes the adaptor-related protein complex 2 sigma (AP2Ï) subunit, cause FHH type 3. These studies have demonstrated Gα(11) to be a key mediator of downstream CaSR signal transduction, and also revealed a role for AP2Ï, which is involved in clathrin-mediated endocytosis, in CaSR signalling and trafficking. Moreover, FHH type 3 has been demonstrated to represent a more severe FHH variant that may lead to symptomatic hypercalcaemia, low bone mineral density and cognitive dysfunction. In addition, calcimimetic and calcilytic drugs, which are positive and negative CaSR allosteric modulators, respectively, have been shown to be of potential benefit for these FHH and ADH disorders
Assessment of fissionable material behaviour in fission chambers
A comprehensive study is performed in order to assess the pertinence of fission chambers coated with different fissile materials for high neutron flux detection. Three neutron scenarios are proposed to study the fast component of a high neutron flux: (i) high neutron flux with a significant thermal contribution such as BR2, (ii) DEMO magnetic fusion reactor, and (iii) IFMIF high flux test module.
In this study, the inventory code ACAB is used to analyze the following questions: (i) impact of different deposits in fission chambers; (ii) effect of the irradiation time/burn-up on the concentration; (iii) impact of activation cross-section uncertainties on the composition of the deposit for all the range of burn-up/irradiation neutron fluences of interest. The complete set of nuclear data (decay, fission yield, activation cross-sections, and uncertainties) provided in the EAF2007 data library are used for this evaluation
A review on plants and biomass wastes as organic green corrosion inhibitors for mild steel in acidic environment
Acid corrosion is a problem pertaining to corrosion that involves an acid solution. It is important to treat metal to preserve its integrity. Thus, acids are utilized to clean and treat metal surfaces. In return, this may lead to overâetching and metal degradation. Corrosion inhibitors were introduced as a solution for the issue. However, there are some problems associated with the usage of conventional corrosion inhibitors. Traces of nitrites and chromates that are present in the inhibi-tors may lead to serious health and environmental issues. As a solution, organic green corrosion inhibitors have been studied to replace the conventional corrosion inhibitors. These inhibitor molecules form a protective layer on top of the metal surface to suppress metal dissolution when added to the acid solution. This process prevents direct contact between the metal surfaces and the acid environment. This study explores the usage of natural resources and biomass wastes as the basis for organic green corrosion inhibitors. This study also provides some suggestions for new biomass wastes that can be studied as new organic corrosion inhibitors, and it is aimed at opening the per-spective of researchers on exploring new organic inhibitors by using natural resources and biomass wastes
Deformation mechanics of sputtered copper layers during nanoindentation tests
The mechanical properties of the thin sputtered copper layer on the SiO2-coated silicon substrate is needed as part of the requirements in quantifying the reliability of the Through-Silicon Via (TSV) interconnects. In this respect, two different Cu coating layers, each from the different sputtering process, are examined. A series of nanoindentation tests are performed on the Cu coating layer samples with indenter speeds ranging from 80 to 400 nm/s, and the indentation depths of 320 nm. The properties of elastic modulus, hardness and the hardening behavior of the Cu coating layers have been quantified. Results show that the coating with higher contamination of C at 8.41 wt. % displays a significant hardening and a peak load level, as reflected in the measured nanoindentation load-displacement curves. However, insignificant effect of the applied probe displacement speeds up to 400 nm/s on the resulting properties of the coating is registered. The Johnson-Cook constitutive equation adequately describes the strain rate-dependent hardening behavior of the Cu coating layer
Challenges Facing Distance Education for Children in Virtual Kindergartens
For kindergarten children, distance education was neither an alternative nor a potential option to in-person schooling before the global COVID-19 pandemic-imposed isolation and mandatory social distancing measures. These measures guaranteed the safety of school staff and children and made the adoption of distance education an urgent necessity for children to continue their education safely. The current study was conducted to reveal the most common challenges that faced childrenâs distance education in virtual kindergartens. The study was conducted from the teachersâ point of view to determine the impact of each of the job title variables and years of experience. The study sample consisted of 32 kindergarten teachers in Jubail Governorate. The research team applied the scale of challenges facing childrenâs education in virtual kindergarten. The results of the study concluded that the most important challenges facing childrenâs education in virtual kindergartens were related to communication skills (79.9%), technical skills (79.5%), educational aids (76.4%), and motivation (69.6%). The results of the study also revealed that there were statistically significant differences in the challenges related to motivation and readiness and in the total challenges facing childrenâs education in the virtual kindergarten from the teachersâ point of view depending on the job titleâthat is, the assistant teacher where the calculated âUâ value reached 28.5 and 37.5. In addition, there was an absence of statistically significant differences due to the variable years of experience, whether in the total number of challenges or in the dimensions of the scale, except for the dimension of communication skills, where the calculated âKa2â value reached 8.755, which is a statistically significant value at the level of significance (0.05)
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