Persistent meningeal signs despite previous treatment for cryptococcal meningitis -- a case report

Corresponding author: Michela M. Fabricius, School of Medicine, University of Missouri-ColumbiaCryptococcal meningitis continues to be a life-threatening fungal infection in patients with HIV. Treatment involves a year of antifungal therapy, and persistent meningeal signs months after treatment initiation are uncommon. We report a case of a 29-year-old male with HIV who was diagnosed with cryptococcal meningitis ten months earlier and underwent induction, maintenance and consolidation therapy and ART. Subsequently, he continued to have persistent headaches and developed severe meningeal signs with leptomeningeal enhancement on imaging. This case discusses the importance of keeping both immune reconstitution inflammatory syndrome and a cryptococcal meningitis relapse in the differential diagnosis for patients with persistent meningeal signs.Michela M. Fabricius, BS (School of Medicine, University of Missouri-Columbia), Shannon Ejiofor, DO (Department of Medicine, University of Missouri-Columbia)Includes bibliographical reference

Long-acting antiretroviral injectable : who would benefit?

"People with HIV (PWH) face many challenges in obtaining HIV care: transportation issues, travel distance, competing life events, etc. Long-acting (LA)-injectable antiretrovirals (ART) could help curb some of these barriers. This project aimed to determine which patients seen at the MU outpatient HIV clinic would be candidates to receive the LA-injectable ART Cabotegravir/Rilpivirine (Cabenuva) as an alternative to a standard oral daily regimen in order to promote further HIV medication adherence."--Introduction

Rare case of gastropericardial fistula after Roux-en-Y gastric bypass

Abstract"Roux-en-Y gastric bypass (RYGB) is a widely used surgery in the management of obesity. Common late complications of RYGB include: Anastomotic stricture, small bowel obstruction, internal hernia, dumping syndrome, cholelithiasis, malnutrition, marginal ulceration, gastro-gastric fistula. Gastropericardial fistulas are an extremely rare but lifethreatening late complication. [less than] 70 cases in modern literature from review in 2016. Mean time of presentation 84 months after surgery (median 60 months). Prior operative risk factors include open or laparoscopic Nissen fundoplication, esophagectomy, hiatal hernia repair, laparoscopic gastric banding and RYGB."--Introduction

Raw Data - “Biomineralization control related to population density under ocean acidification"

<p>Raw data about the manuscript "“Biomineralization control related to population density under ocean acidification" submitted to Nature Climate Change.</p> <p> </p> <p> </p