83 research outputs found
A Research on School Principals’ Recognition of Current Situations and Issues in Regard to the Promotion of ICT Use at Schools
本稿の目的は,校長を対象とした調査研究を通じて,教育の情報化の現状と課題に関する校長の認識を把握し,教育の情報化の推進に寄与しうる基礎的知見を得ることである。そのために,具体的には以下の点について検討した。① ICT の利用に関する現任校や自身の現状に対する校長の認識,②学校全体としてICT の活用を進めていくための改善の必要性に対する校長の認識,③ ICT の利用に関する現状認識の差異による改善の必要性に関する認識の差異,④教育の情報化を進めたり,ICT を活用したりするなかで,当初予想していなかった成果・効果,⑤教育の情報化を進めたり,ICT を活用したりするなかで,当初予想していなかった課題・問題
Associations between toe grip strength and hallux valgus, toe curl ability, and foot arch height in Japanese adults aged 20 to 79 years: a cross-sectional study
Observation of gigantic spin conversion anisotropy in bismuth
Whilst the g-factor can be anisotropic due to the spin-orbit interaction
(SOI), its existence in solids cannot be simply asserted from a band structure,
which hinders progress on studies from such the viewpoints. The g-factor in
bismuth (Bi) is largely anisotropic; especially for holes at T-point, the
g-factor perpendicular to the trigonal axis is negligibly small (< 0.112),
whereas the g-factor along the trigonal axis is very large (62.7). We clarified
in this work that the large g- factor anisotropy gives rise to the gigantic
spin conversion anisotropy in Bi from experimental and theoretical approaches.
Spin-torque ferromagnetic resonance was applied to estimate the spin conversion
efficiency in rhombohedral (110) Bi to be 17%, which is unlike the negligibly
small efficiency in Bi(111). Harmonic Hall measurements supports the large spin
conversion efficiency in Bi(110). This is the first observation of gigantic
spin conversion anisotropy as the clear manifestation of the g-factor
anisotropy. Beyond the emblematic case of Bi, our study unveiled the
significance of the g-factor anisotropy in condensed-matter physics and can
pave a pathway toward establishing novel spin physics under g-factor control.Comment: 28 pages, 7 figure
STATIC AND DYNAMIC BEHAVIOR OF LENS-TYPE SHEAR PANEL DAMPERS FOR HIGHWAY BRIDGE BEARING
This paper describes a lens-type shear panel damper newly developed for highway bridge bearing. It has the form of concave lens shape made of low-yield steel LY 100. Both low yield strength and high ductility are the major requirements for damping devices. Response by static and dynamic shear tests results in rectangular sharpe of load-displacement hysteretic loops with high quality damping. Failure at the ultimate state highly depends on the cumulative deformation capacity of panel. Damage and life cycles can be estimated by Miner's rule. The analytical estimates agree well with the test findings. Large deformation of steel with high speed strain rate generates a lot of heat leading to high temperature of 300~400 ℃ on swface. Earthquake energy is converted to both strain and heate nergies wof hich results in large energy dissipation
Design and Experimental Performance Evaluation of Lens-type Shear Panel Dampers for Highway Bridge Bearings
This paper describes lins-type shear damper newly developed for highway bridge bearing. It utilizes low-yield steel LY100 and concave lins-shape panels. Both properties provide low strength and high ductility which are major requirements for damping devices, then contributes to high energy dissipation against seismic motion. Large deformation due to high speed strain velocity causes steel lens plate heating up to 400-500 centigrade in a moment. Earthquake energy is converted both to strain energy and heat energy. Cumulative deformation capacity of lens identity determines ultimate state of failures associated with strength and life time, dependent on time history of level-2 desibn earthquake(EQ). Fracture is roughly estimated by Miners rule esing damage index method. Prediction matches well with testing results. As case study with dampers, dynamic analysis on the existing continuous bridges has been conducted with some design parameters. The base shear acceleration due to livel-2 earthquake reduces down to 0.45g~0.5g from 0.8g of lead rubber bearing system. For planning of bridge system with dampers, 1-DOF model is simply useful to roughly know the base shear with dampers at the initial stage of planning onil when dead load is known. Design methods and experimental performance evaliation results are reported
Retrospective Study of the Correlation Between Pathological Tumor Size and Survival After Curative Resection of T3 Pancreatic Adenocarcinoma: Proposal for Reclassification of the Tumor Extending Beyond the Pancreas Based on Tumor Size
BackgroundEven though most patients who undergo resection of pancreatic adenocarcinoma have T3 disease with extra-pancreatic tumor extension, T3 disease is not currently classified by tumor size. The aim of this study was to modify the current TNM classification of pancreatic adenocarcinoma to reflect the influence of tumor size.MethodsA total of 847 consecutive pancreatectomy patients were recruited from multiple centers. Optimum tumor size cutoff values were calculated by receiver operating characteristics analysis for tumors limited to the pancreas (T1/2) and for T3 tumors. In our modified TNM classification, stage II was divided into stages IIA (T3aN0M0), IIB (T3bN0M0), and IIC (T1-3bN1M0) using tumor size cutoff values. The usefulness of the new classification was compared with that of the current classification using Akaike’s information criterion (AIC).ResultsThe optimum tumor size cutoff value distinguishing T1 and T2 was 2 cm, while T3 was divided into T3a and T3b at a tumor size of 3 cm. The median survival time of the stages IIA, IIB, and IIC were 44.7, 27.6, and 20.3 months, respectively. There were significant differences of survival between stages IIA and IIB (P = 0.02) and between stages IIB and IIC (P = 0.03). The new classification showed better performance compared with the current classification based on the AIC value.ConclusionsThis proposed new TNM classification reflects the influence of tumor size in patients with extra-pancreatic tumor extension (T3 disease), and the classification is useful for predicting mortality
2005年夏現在の市販豆腐に含まれる組換え遺伝子の検出
The presence of modified genes resistant to a chemical herbicide Roundup Ready (glyphosate) in commercially available bean curd (tofu) labeled as modified gene-free was examined by the PCR method. Samples were taken from twelve brands of bean curd all available on the market and bought during August and September 2005. For DNA extraction, PCR analysis was conducted from primers based on the disclosed Roundup Ready-resistant expression sequence and soybean lectin expression sequence using a DNeasy Plant Mini Kit produced by Qiagen, and the results were confirmed by electrophoresis. As a result a clear band that appears to derive from modified genes was detected in one brand, and a trace of such a band was detected in two other brands. In an analysis of unsorted ration for livestock carried out for comparison, a clear band that appears to derive from modified genes was detected
ピエゾ型機械受容イオンチャネル1は間葉系幹細胞の分化運命決定の調節因子として機能する
The extracellular environment regulates the dynamic behaviors of cells. However, the effects of hydrostatic pressure (HP) on cell fate determination of mesenchymal stem cells (MSCs) are not clearly understood. Here, we established a cell culture chamber to control HP. Using this system, we found that the promotion of osteogenic differentiation by HP is depend on bone morphogenetic protein 2 (BMP2) expression regulated by Piezo type mechanosensitive ion channel component 1 (PIEZO1) in MSCs. The PIEZO1 was expressed and induced after HP loading in primary MSCs and MSC lines, UE7T-13 and SDP11. HP and Yoda1, an activator of PIEZO1, promoted BMP2 expression and osteoblast differentiation, whereas inhibits adipocyte differentiation. Conversely, PIEZO1 inhibition reduced osteoblast differentiation and BMP2 expression. Furthermore, Blocking of BMP2 function by noggin inhibits HP induced osteogenic maker genes expression. In addition, in an in vivo model of medaka with HP loading, HP promoted caudal fin ray development whereas inhibition of piezo1 using GsMTx4 suppressed its development. Thus, our results suggested that PIEZO1 is responsible for HP and could functions as a factor for cell fate determination of MSCs by regulating BMP2 expression
Percutaneous Direct Puncture of Retropancreatic Splenic Vein and Portal Thrombectomy in a Patient With Liver Transplantation and Simultaneous Splenectomy
Portal vein thrombosis following liver transplantation is generally managed by endovascular treatment. Although several techniques are available for portal venous access, trans-splenic access is of interest because it avoids damage to the liver graft. However, the spleen cannot be punctured to access the portal vein after splenectomy. We herein report a case of portal vein thrombosis following living donor liver transplantation with simultaneous splenectomy successfully treated by percutaneous intervention with direct puncture of the retropancreatic splenic vein. The splenic vein was punctured under computed tomography guidance in the prone position. Portal venography revealed a contrast defect due to a thrombus in the extrahepatic to intrahepatic portal vein. The portal vein was reopened after thrombectomy, and the portal vein thrombosis did not recur for 2 y. The technique and advantages of our approach are described
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