Frontally mediated inhibitory processing and white matter microstructure: age and alcoholism effects

RationaleThe NOGO P3 event-related potential is a sensitive marker of alcoholism, relates to EEG oscillation in the δ and θ frequency ranges, and reflects activation of an inhibitory processing network. Degradation of white matter tracts related to age or alcoholism should negatively affect the oscillatory activity within the network.ObjectiveThis study aims to evaluate the effect of alcoholism and age on δ and θ oscillations and the relationship between these oscillations and measures of white matter microstructural integrity.MethodsData from ten long-term alcoholics to 25 nonalcoholic controls were used to derive P3 from Fz, Cz, and Pz using a visual GO/NOGO protocol. Total power and across trial phase synchrony measures were calculated for δ and θ frequencies. DTI, 1.5 T, data formed the basis of quantitative fiber tracking in the left and right cingulate bundles and the genu and splenium of the corpus callosum. Fractional anisotropy and diffusivity (λL and λT) measures were calculated from each tract.ResultsNOGO P3 amplitude and δ power at Cz were smaller in alcoholics than controls. Lower δ total power was related to higher λT in the left and right cingulate bundles. GO P3 amplitude was lower and GO P3 latency was longer with advancing age, but none of the time-frequency analysis measures displayed significant age or diagnosis effects.ConclusionsThe relation of δ total power at CZ with λT in the cingulate bundles provides correlational evidence for a functional role of fronto-parietal white matter tracts in inhibitory processing

Earth’s magnetosphere and outer radiation belt under sub-Alfvénic solar wind

The interaction between Earth's magnetic field and the solar wind results in the formation of a collisionless bow shock 60,000–100,000 km upstream of our planet, as long as the solar wind fast magnetosonic Mach (hereafter Mach) number exceeds unity. Here, we present one of those extremely rare instances, when the solar wind Mach number reached steady values <1 for several hours on 17 January 2013. Simultaneous measurements by more than ten spacecraft in the near-Earth environment reveal the evanescence of the bow shock, the sunward motion of the magnetopause and the extremely rapid and intense loss of electrons in the outer radiation belt. This study allows us to directly observe the state of the inner magnetosphere, including the radiation belts during a type of solar wind-magnetosphere coupling which is unusual for planets in our solar system but may be common for close-in extrasolar planets

Dynamics of Group Knowledge Production in Facilitated Modelling Workshops: An Exploratory Study

The final publication is available at Springer via http://dx.doi.org/10.1007/s10726-014-9398-2The term ‘facilitated modelling’ is used in the literature to characterise an approach to structuring problems, developing options and evaluating decisions by groups working in a model-supported workshop environment, and assisted by a facilitator. The approach involves an interactive process by which models are jointly developed with group members interacting face-to-face, with or without computer support. The models produced are used to inform negotiations about the nature of the issues faced by the group, and how to address them. While the facilitated modelling literature is impressive, published empirical research rarely examines what actually happens in a facilitated modelling environment. The present study addresses this gap by reporting on exploratory empirical research undertaken to closely examine the conduct of facilitated modelling within its actual context of immediate use, namely, the workshop. Drawing on the knowledge-perspective of group communication, we conducted a micro-level analysis of a transcript of a facilitated modelling workshop held with the management team of an Alternative Food Network in the UK. Our analysis suggests that facilitated modelling interactions can take the form of three distinct group knowledge production patterns: generative, collaborative and assertive. Further, each pattern is characterised by a particular mix of communicative behaviours and model-supported interactions that has implications for the creation of new knowledge within the workshop. Our findings contribute to increase our understanding of the nature of facilitated modelling within its context of use