116 research outputs found
Near-glacier surveying of a subglacial discharge plume: Implications for plume parameterizations
At tidewater glaciers, plume dynamics affect submarine melting, fjord circulation, and the mixing of meltwater. Models often rely on buoyant plume theory to parameterize plumes and submarine melting; however, these parameterizations are largely untested due to a dearth of nearâglacier measurements. Here we present a highâresolution ocean survey by ship and remotely operated boat near the terminus of Kangerlussuup Sermia in west Greenland. These novel observations reveal the 3âD structure and transport of a nearâsurface plume, originating at a large undercut conduit in the glacier terminus, that is inconsistent with axisymmetric plume theory, the most common representation of plumes in oceanâglacier models. Instead, the observations suggest a wider upwelling plumeâa âtruncatedâ line plume of âŒ200 m widthâwith higher entrainment and plumeâdriven melt compared to the typical axisymmetric representation. Our results highlight the importance of a subglacial outlet's geometry in controlling plume dynamics, with implications for parameterizing the exchange flow and submarine melt in glacial fjord models.NNX12AP50
Precision spectroscopy of helium in a magic wavelength optical dipole trap
Improvements in both theory and frequency metrology of few-electron systems
such as hydrogen and helium have enabled increasingly sensitive tests of
quantum electrodynamics (QED), as well as ever more accurate determinations of
fundamental constants and the size of the nucleus. At the same time advances in
cooling and trapping of neutral atoms have revolutionized the development of
increasingly accurate atomic clocks. Here, we combine these fields to reach the
highest precision on an optical tranistion in the helium atom to date by
employing a Bose-Einstein condensate confined in a magic wavelength optical
dipole trap. The measured transition accurately connects the ortho- and
parastates of helium and constitutes a stringent test of QED theory. In
addition we test polarizability calculations and ultracold scattering
properties of the helium atom. Finally, our measurement probes the size of the
nucleus at a level exceeding the projected accuracy of muonic helium
measurements currently being performed in the context of the proton radius
puzzle
Emerging roles of ATF2 and the dynamic AP1 network in cancer
Cooperation among transcription factors is central for their ability to execute specific transcriptional programmes. The AP1 complex exemplifies a network of transcription factors that function in unison under normal circumstances and during the course of tumour development and progression. This Perspective summarizes our current understanding of the changes in members of the AP1 complex and the role of ATF2 as part of this complex in tumorigenesis.Fil: Lopez Bergami, Pablo Roberto. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Instituto de BiologĂa y Medicina Experimental (i); Argentina; ArgentinaFil: Lau, Eric . Burnham Institute for Medical Research; Estados UnidosFil: Ronai, Zeev . Burnham Institute for Medical Research; Estados Unido
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