Fine-needle Aspiration Biopsy For Breast Lesions: A Comparison Between Two Devices For Obtaining Cytological Samples

Context and Objective: Fine-needle aspiration biopsy has been accepted worldwide for breast lesions. However, some questions remain, including the appropriateness of the puncture method. The objective of this work was to compare aspirates obtained by the auto-vacuum device and by the syringe pistol holder. Design and Setting: Randomized trial for validation of diagnostic method, at Hospital das Clinicas do Universidade Federal de Goiás and Hospital Araújo Jorge, Goiânio. Methods: 351 patients presenting breast lumps underwent fine-needle aspiration biopsy, either with the auto-vacuum device or the syringe pistol holder. A single cytopathologist analyzed all of the cytology slides. The rates of insufficient material, cellularity, cell distortion and background hemorrhage were evaluated. Results: The percentages of insufficient material were 16% and 22% (p = 0.18), for the auto-vacuum and pistol aspirates, respectively. Good cellularity was seen in 34% of autovacuum and 29% of pistol samples (p = 0.4). Cell distortion was seen in 31 and 26 cases, respectively (p = 07). Background hemorrhage occurred in 63 (35%) and 54 cases (31%) (p = 0.2), for auto-vacuum and pistol. The sensitivity was 88% and 86%; specificity 99% and 100%, positive predictive value 96% and and 100%, negative predictive value 96% and 95% and total occuracy 76% and 75% for the auto-vacuum and pistol, respectively. Conclusion: The results obtained from the two fine-needle aspiration biopsy methods were equivalent. Therefore, the auto-vacuum device is a good option for obtaining aspirates for cytology.1236271276Catania, S., Ciatto, S., Breast cytology: Instruments and technique (1992) Breast Cytology in Clinical Practice, pp. 11-60. , In: Ciatto S, editor. 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Efeitos dos excessos de alumínio, cloro e manganês em dois cultivares de soja (Glycine max (L.) Merrill)

Two soybean cultivars, Santa Rosa and FV-1, were grown in nutrient solution in the presence of high concentrations of Al (24 ppm), CI (1750 ppm) and Mn (25 ppm). Observations, measurements and chemical analyses allowed for the following conclusions to be drawn: (1) symptoms of toxicity are in agreement with those described in the literatura; (2) the detrimental effect obeyed the decreasing order - Mn Al CI; (3) dry matter production by the variety UFV - 1 was relatively more affected by the treatments; (4) leaf analyses do not provide a reliable indication of the sensitivity of the two varieties to the high levels of the three elements in the substrate; (5) Ca/Al ratio in the roots keeps a good relationship with the relative tolerance of the two cultivas to excess Al in the medium.Dois cultivares de soja, Santa Rosa e UFV-1, foram cultivados em solução nutritiva na presença de excesso de alumínio, cloro e manganês. Além de provocar o aparecimento de sintomas foliares (cloro e manganês) ou radiculares (alumínio), os elementos em excesso causaram diminuições no crescimento e impediram a produção de vagens. A análise mineral das folhas mostrou a influência dos tratamentos na composição do tecido