51 research outputs found

    Introduction: Crime and Deviance through the Lens of Popular Culture

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    The introductory chapter sets out the collection’s theoretical framework, which favours a view of popular culture as an arena where issues of crime, deviance, criminal victimisation and justice are debated and negotiated. It draws attention to the mediatisation of the crime problem and the increasing academic interest in the interrelationship between crime, deviance and popular culture in the twenty-first century. In addition, this chapter introduces the five thematic sections of the collection and outlines the topics addressed in the chapters of each section

    Comparative Genomics of Bordetella pertussis Reveals Progressive Gene Loss in Finnish Strains

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    BACKGROUND: Bordetella pertussis is a gram-negative bacterium that infects the human respiratory tract and causes pertussis or whooping cough. The disease has resurged in many countries including Finland where the whole-cell pertussis vaccine has been used for more than 50 years. Antigenic divergence has been observed between vaccine strains and clinical isolates in Finland. To better understand genome evolution in B. pertussis circulating in the immunized population, we developed an oligonucleotide-based microarray for comparative genomic analysis of Finnish strains isolated during the period of 50 years. METHODOLOGY/PRINCIPAL FINDINGS: The microarray consisted of 3,582 oligonucleotides (70-mer) and covered 94% of 3,816 ORFs of Tohama I, the strain of which the genome has been sequenced. Twenty isolates from 1953 to 2004 were studied together with two Finnish vaccine strains and two international reference strains. The isolates were selected according to their characteristics, e.g. the year and place of isolation and pulsed-field gel electrophoresis profiles. Genomic DNA of the tested strains, along with reference DNA of Tohama I strain, was labelled and hybridized. The absence of genes as established with microarrays, was confirmed by PCR. Compared with the Tohama I strain, Finnish isolates lost 7 (8.6 kb) to 49 (55.3 kb) genes, clustered in one to four distinct loci. The number of lost genes increased with time, and one third of lost genes had functions related to inorganic ion transport and metabolism, or energy production and conversion. All four loci of lost genes were flanked by the insertion sequence element IS481. CONCLUSION/SIGNIFICANCE: Our results showed that the progressive gene loss occurred in Finnish B. pertussis strains isolated during a period of 50 years and confirmed that B. pertussis is dynamic and is continuously evolving, suggesting that the bacterium may use gene loss as one strategy to adapt to highly immunized populations

    Directing Modernist Spirituality: Evelyn Underhill, the Subliminal Consciousness and Spiritual Direction

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    Outlining an alternative trajectory for modernist spirituality to that traced in Pericles Lewis’s 'Religious Experience and the Modernist Novel' (2010), I argue that modernist religious thought, far from playing heir to the long march of secularization, was in fact conditioned by a late-nineteenth-century cultural crisis that issued in a range of religious experiments and renewals, one of which was Evelyn Underhill’s 'Mysticism: A Study in the Nature and Development of Man’s Spiritual Consciousness' (1911), a text that not only brought together mystical traditions and scientific discoveries, but also used this interdisciplinary remit to counter existing secularizing perspectives. An important dimension of Underhill’s work was its collaborative nature; it offers, I argue, not access to rarefied enlightenment, but rather a bold attempt to navigate a treacherous religious landscape

    A Reluctant Leavisite: Martin Amis’s “Higher Journalism”

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    Change fauna complexes fungus gnats (Diptera, Sciaroidea) under the influence of recreational loading for example "Siberian Botanical Garden"

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    Reproduced with permission of Palgrave Macmillan. "This extract is taken from the author's original manuscript and has not been edited. The definitive version of this piece may be found in Emotions and Understanding by Ylva Gustafsson, Camilla Kronqvist and Michael McEachrane which can be purchased from www.palgrave.com .

    hardy and his readers

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