Monitoring of soil organic carbon and nitrogen stocks in different land use under surface water erosion in a semi-arid drainage basin of Iran

Soil organic carbon (SOC) and soil nitrogen (SN) are the principal components in soil quality assessment, and in mitigation the global greenhouse effect. In Iran, little information exists on the stocks of SOC and SN. SOC and SN stocks are a function of the SOC and SN concentrations and the bulk density of the soil that are prone to changes under land use types and soil erosion. The objective of this study was to evaluate SOC and SN stock in different land use types under surface erosion at catchment scale. In view of this, bulk density, SOC and SN concentration were measured in 39 different sampling sites of three main groups of land use affected by surface erosion namely, rangeland, crop field, and forest land at Taleghani catchment, Khoramabad, Iran. The results showed that SOC and SN stock under all land use types was significantly different (P < 0.01). SOC and SN stocks were greatest in the forest land use. The SOC stock for the 30 cm soil layer in different land uses varied in order forest (66.9 Mg ha 121) > rangeland (63.3 Mg ha 121) > crop field (47.2 Mg ha 121; P < 0.01). Also the SN stock had the same trend in all studied land uses. These results can be useful as a scientific basis for selecting the proper soil management as a simple and low-cost approach to mitigate the SOC and SN loss. \ua9JASE

Assessing growth parameters of children with congenital hypothyroidism subject to levothyroxine treatment compared to normal growth parameters in healthy newborns

Background and aims: Congenital hypothyroidism (CH) is one of the most common treatable physical growth disorders leading to mental retardation. Most cases of this disease can be detected through the neonatal screening program. Given the high prevalence of this disease and the implementation of screening programs in recent years in Iran, this study aimed to assess the growth indices of newborns with CH. Methods: In this retrospective cohort study, 66 newborns with CH detected in the screening program in Shahrekord were selected by a census sampling method. Overall, 125 healthy newborns were also selected as controls by the convenience sampling technique according to the inclusion and exclusion criteria. The height, weight, head circumference, and body mass index (BMI) of the samples were measured and then the mean, median, standard deviation, as well as the 3rd, 15th, 25th, 50th, 75th, 85th, and 97th percentiles in the two groups were determined and compared based on gender and age group. Results: The height, weight, head circumference, and BMI of the boys, in addition to the head circumference and BMI of the girls, were not significantly different from those of the controls (P>0.05). However, the height and weight of the girls were significantly lower compared to those in the control group, although the difference in the weight was corrected at the age of 9 months. Conclusion: In general, the growth indices of newborns with CH were lower than those of the controls. This difference was significant only for the weight and height of girls with CH. Keywords: Congenital hypothyroidism, Growth indices, Newborn Screenin

Aberrant Expression of Three New Members of IL-1 Family (IL-36α, IL-37 and IL-38) in Patients with Multiple Sclerosis

Background & Objective: Multiple sclerosis (MS) is a neurodegenerative disease that is characterized by demyelination and neuronal dysfunction. The study of the expression of cytokine genes seems to be an appropriate option for assessing their potential for the onset and development of the disease. Therefore, in the present study, changes in the expression of three interleukins (IL-36α, IL-37, and IL-38) in MS and their association with clinical factors were investigated. Material & Methods: In this study, blood samples of 45 MS patients and 45 healthy controls were enrolled. Relative expression of genes was evaluated using the real-time PCR. Finally, the pattern of expression was analyzed by using statistical analyses. In the next step, the relationship between clinical characteristics and IL-36α, IL-37, and IL-38 expression was investigated. Results: The results showed that IL-36α and IL-37 increased in MS patient (1.8 and 3.5 fold respectively, P<0.01).  Moreover, a significant reduction in IL-38 was observed in MS samples (0.21 fold, P<0.01). The dysregulation in ILs expression was associated with clinical features. Conclusion: As a result, the two studied IL-1 family members (IL-36α and IL-37) may contribute to the progression of MS, so that increase in their expression is associated with EDSS disability and duration of disease. Another member of IL-1 family, IL-38 has a protective effect on MS diseases, and its downregulation is related to severe disability. Further investigation can help to determine accurate functional role of 3 interleukins in MS development

Comparison of Pattern of Alcohol Consumption and Related Factors in Patients Referred to Referral Hospitals in Shahrekord, Iran (2016-2017)

Background and aims: The aim of the present study was to investigate the pattern of alcohol consumption and its related factors in the patients referring to hospitals.  Methods: A hospital-based case control study was carried out in Shahrekord during 2016-2017. A total of 150 individuals who had self-report of alcohol consumption and history of alcoholism entered into the case group based on the convenience sampling method. Likewise, 300 individuals who did not have self-report of alcohol consumption entered into the control group. Group matching was performed based on the date of admission to the hospital, type of disease, complications, and duration of the disease. This study explored the pattern of alcohol consumption variables, spiritual health, quality of life, and general health. Odds ratios (ORs) with a 95 confidence interval (CI) were calculated as well.  Results: The causes of onset of alcohol consumption were curiosity (41.40), social class and imitation of others (17.40), and life problems (15.30). Further, the causes of continued alcohol consumption were attributed to the interest in taste and smelling (23.30), emotional problems (20), as well as loneliness feeling and life problems (12.60). The mean of general health scores in the case and control groups were 29.8± 5 and 29.3± 4, respectively (P = 0.296). The mean of the quality of life in the case group and control group were 32.13± 7 and 32.11± 5, respectively (P = 0.98). The differences in the scores of spiritual health in two groups were not statistically significant (P = 0.96).  Conclusion: An attempt should be made to improve the strategies to satisfy the emotional sense and health recreations of society

The potential prognostic and therapeutic application of tissue and circulating microRNAs in cervical cancer

Cervical cancer (CC) is a common malignancy in women and a major cause of cancer- related mortality globally. Some novel biomarkers may enable the early diagnosis and monitoring of CC. MicroRNAs are small noncoding RNAs that control gene translation at a post transcriptional level. Hence the deregulation of these molecules can cause many diseases. There appears to be an association between aberrant miRNA expression and CC, but the molecular mechanisms involved in the development of CC remain unknown. The upregulation of some circulating miRNAs, e.g. miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue specific-miRNAs, e.g. miR-7, miR-10a, miR-17-5p, miR-135b, miR-149 and miR-203 has been found in patients with CC. There is also growing evidence for the importance of miRNAs in the development of drug-resistance. This review therefore highlights recently published preclinical and clinical investigation performed on tissue-specific and circulating miRNAs, as potential biomarkers for the detection of patients at early stages of CC, in the prediction of prognosis, and monitoring of their response to therapy. Key word: cervical cancer, CIN, MiRNA, circulating biomarker, tissue-specific biomarker, HP

Plotinus and Suhrawardi on the Immortality of the Soul

The question of the immortality of the soul – which is directly relevant to any discussion on the true nature of human being - is an important and even central theme of both Plotinus and Suhrawardi, the latter being known as the founder of the Perso-Islamic Illuminationistschool of philosophy.Plotinus and Suhrawardiboth considered the soul to be the essence of the human being, hence,both thinkers engaged in some kind of ‘dualist anthropology’, although through two different approaches.In other words, they believed that man is not a simple thing, but a composite of ‘soul’ and ‘body’. Plotinus’ discussion of the relation of ‘soul’ to ‘body’ is a particular instance of his doctrine of participation, where higher is related to lower, intelligible to sensible, and form to matter.Individual human beings are composed of ‘soul’ and ‘body’, but body itself consists of ‘matter’ and ‘form’.  Soul as the ‘form’ of the body, is a part of the World-Soul, but the individual soul is immaterial and immortal and linked with the ‘Intellect’ (nous).Suhrawardidid not concern himself with any kind of causal relation between ‘body’ and ‘soul’.In his teachings, the ‘Lordly Light’(nūr-iispahbad)- i.e. the vicegerent of the ‘Light of lights’ (nūr al-anwār)in the human soul – is connected with the body by means of the ‘animal soul’ (rūḥḥayawāniyya) and leaves the body for its original home in the angelic realm as soon as death destroys the equilibrium of the bodily elements

Monitoring of soil organic carbon and nitrogen stocks in different land use under surface water erosion in a semi-arid drainage basin of Iran

Soil organic carbon (SOC) and soil nitrogen (SN) are the principal components in soil quality assessment, and in mitigation the global greenhouse effect. In Iran, little information exists on the stocks of SOC and SN. SOC and SN stocks are a function of the SOC and SN concentrations and the bulk density of the soil that are prone to changes under land use types and soil erosion. The objective of this study was to evaluate SOC and SN stock in different land use types under surface erosion at catchment scale. In view of this, bulk density, SOC and SN concentration were measured in 39 different sampling sites of three main groups of land use affected by surface erosion namely, rangeland, crop field, and forest land at Taleghani catchment, Khoramabad, Iran. The results showed that SOC and SN stock under all land use types was significantly different (P < 0.01). SOC and SN stocks were greatest in the forest land use. The SOC stock for the 30 cm soil layer in different land uses varied in order forest (66.9 Mg ha−1) > rangeland (63.3 Mg ha−1) > crop field (47.2 Mg ha−1; P < 0.01). Also the SN stock had the same trend in all studied land uses. These results can be useful as a scientific basis for selecting the proper soil management as a simple and low-cost approach to mitigate the SOC and SN loss. ©JASE

Monitoring of soil organic carbon and nitrogen stocks in different land use under surface water erosion in a semi-arid drainage basin of Iran

Soil organic carbon (SOC) and soil nitrogen (SN) are the principal components in soil quality assessment, and in mitigation the global greenhouse effect. In Iran, little information exists on the stocks of SOC and SN. SOC and SN stocks are a function of the SOC and SN concentrations and the bulk density of the soil that are prone to changes under land use types and soil erosion. The objective of this study was to evaluate SOC and SN stock in different land use types under surface erosion at catchment scale. In view of this, bulk density, SOC and SN concentration were measured in 39 different sampling sites of three main groups of land use affected by surface erosion namely, rangeland, crop field, and forest land at Taleghani catchment, Khoramabad, Iran. The results showed that SOC and SN stock under all land use types was significantly different (P < 0.01). SOC and SN stocks were greatest in the forest land use. The SOC stock for the 30 cm soil layer in different land uses varied in order forest (66.9 Mg ha−1) > rangeland (63.3 Mg ha−1) > crop field (47.2 Mg ha−1; P < 0.01). Also the SN stock had the same trend in all studied land uses. These results can be useful as a scientific basis for selecting the proper soil management as a simple and low-cost approach to mitigate the SOC and SN loss. ©JASE

Burnout and its relationship to self- reported quality of patient care and adverse events during COVID- 19: A cross- sectional online survey among nurses

Aims: To assess nurses' burnout and its association with their perceived quality of patient care and occurrence of adverse events (AEs) during COVID- 19. Background: Burnout is a serious problem among nursing staff internationally with negative impacts on the quality of care and patient safety. Methods: We conducted a cross- sectional online study among 1,004 Iranian nurses through the convenience sampling technique. Data were collected using the Maslach Burnout Inventory, five items of questions related to self- reported poor patient care quality and estimated occurrence of AEs. Results: Prevalence of high burnout among nurses was 31.5%. The risk of AEs ranged from 26.1% to 71.7%. Self- reported quality of patient care was found to be poor. A positive correlation was found between emotional exhaustion and depersonalization scores and patient care quality, whereas a negative correlation was found between personal accomplishment scores and all poor care item scores. Depersonalization was found to increase the risk of the onset of all AEs (odds ratio [OR] = 1.06– 1.08). Also, Personal accomplishmentreduced the risk of occurrence of ‘medication errors’ (OR = 0.99) and the onset of ‘patient and their family verbal abuse’ (OR = 0.97). Conclusions: Our findings confirmed the hypothesis that a higher degree of burnout is correlated with a perceived higher number of AEs and reduced perceived patient care quality. Implications for Nursing Management: Reducing burnout among nurses through implementing interventions may be an effective strategy to enhance patient care quality and reduce the number of AEs in Iranian public hospitals. Therefore, in order to minimize work burnout, primary approaches include access to psychosocial support, including Web- based services, psychological first aid, mental support hotlines and self- care techniques during the COVID- 19 pandemic

Effectiveness of extracorporeal shockwave therapy for chronic Achilles tendinopathy: A randomized clinical trial

Background: In this study, we aimed to evaluate the effectiveness of extracorporeal shockwave treatment (ESWT) on pain and ankle-hindfoot scale of the American Orthopedic Foot and Ankle Society (AOFAS) score of patients with chronic Achilles tendinopathy (AT). Materials and Methods: In this double-blind clinical trial, 43 patients with chronic AT were selected and randomly allocated in two groups to receive a basic treatment with ESWT or sham SWT (radial and focused shock waves, four sessions once a week for 4 weeks). AOFAS and pain scores for each patient were recorded at baseline (before intervention), immediately after intervention, and 4 and 16 weeks after intervention using AOFAS and visual analog scale (VAS) scaling method. Results: A total of 43 patients (22 ESWT and 21 sham SWT) were participated in this study. Both groups improved during the treatment and follow-up period. The mean VAS score decreased from 7.55 to 3 in the intervention group and from 7.70 to 4.30 in the sham SWT group. Mean AOFAS and VAS scores were significantly different between ESWT and no ESWT groups at 16 weeks of follow-up (P = 0.013) (P = 0.47). There was no significant difference in terms of AOFAS and VAS scores between both the groups in the other follow-up times. Conclusion: Overall, ESWT causes decrease in VAS score and increase in AOFAS score. However, due to the small sample size, the results were not statistically significant. It is recommended to plan more interventional studies with larger sample size in the future