3,474 research outputs found

    Predica della vita e miracoli della B. Madre Teresa di Gesù Carmelitana

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    Copia digital : Junta de Castilla y León. Consejería de Cultura y Turismo, 2014Port. con graba. calc.Sign.:A-K4

    Comment on Higgs Inflation and Naturalness

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    We rebut the recent claim (arXiv:0912.5463) that Einstein-frame scattering in the Higgs inflation model is unitary above the cut-off energy Lambda ~ Mp/xi. We show explicitly how unitarity problems arise in both the Einstein and Jordan frames of the theory. In a covariant gauge they arise from non-minimal Higgs self-couplings, which cannot be removed by field redefinitions because the target space is not flat. In unitary gauge, where there is only a single scalar which can be redefined to achieve canonical kinetic terms, the unitarity problems arise through non-minimal Higgs-gauge couplings.Comment: 5 pages, 1 figure V3: Journal Versio

    Recadastro imobili?rio da cidade de Sol?nea-PB: necessidade, influ?ncia e reflexos para o desenvolvimento socioecon?mico local

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    A presente pesquisa cient?fica tenciona a reflex?o tem?tica quanto ? urg?ncia e relev?ncia de processamento de recadastro tribut?rio imobili?rio da cidade de Sol?nea-PB, sob o fundamento de ser o recenseamento instrumento apto ao melhoramento da conjuntura socioecon?mica local por viabilizar o incremento da arrecada??o pr?pria. Tendo-se por objetivo central explorar os benef?cios oriundos da atualiza??o cadastral imobili?ria, busca-se responder qual a influ?ncia da n?o atualidade do hodierno cadastro t?cnico imobili?rio solanense para o quadro final de receitas pr?prias e cen?rio sociopol?tico municipal. Neste ?nterim, a sele??o do objeto de estudo tem cunho, prioritariamente, acad?mico e social. A justifica??o acad?mica da alterca??o ressente-se da exiguidade de seus debates te?ricos, assoalhando-se no imperativo de debat?-lo como elemento propiciador da sustenta??o arrecadat?ria e desenvolvimento socioecon?mico pr?prios das municipalidades. De outra sorte, a preponder?ncia social deste trabalho ascende da necessidade de an?lise do papel que cumpre o Estado, visto em sua menor representa??o federativa (munic?pio), no que diz respeito ? sua compet?ncia de busca pr?pria pela promo??o do bem estar coletivo. A metodologia empregada ? resultado do manejo de t?cnicas de pesquisa aplicada, com uso de abordagem de fei??es quali-quantitativa, cunho eminentemente explorat?rio e linha de racioc?nio dedutiva. Ante o exposto, a aprecia??o cr?tica esbo?ada ao final permite o entendimento mais completo da problem?tica aventada e o levantamento de preju?zos atualmente suportados pela edilidade (crescimento habitacional desordenado e prec?rio, desrespeito ambiental, mobilidade urbana e tr?nsito ca?ticos, elei??o incorreta das prioridades locais, arrecada??o pr?pria aqu?m da pass?vel de realiza??o, estagna??o do desenvolvimento local, dentre outros), a eles contrapondo, de imediato, os vindouros impactos positivos oriundos da atualiza??o (e manuten??o) cadastral imobili?ria no incremento das receitas p?blicas, que s?o principalmente: otimiza??o do planejamento urbano, melhoramento da conjuntura socioecon?mica local e boa governan?a

    Nonminimal Couplings in the Early Universe: Multifield Models of Inflation and the Latest Observations

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    Models of cosmic inflation suggest that our universe underwent an early phase of accelerated expansion, driven by the dynamics of one or more scalar fields. Inflationary models make specific, quantitative predictions for several observable quantities, including particular patterns of temperature anistropies in the cosmic microwave background radiation. Realistic models of high-energy physics include many scalar fields at high energies. Moreover, we may expect these fields to have nonminimal couplings to the spacetime curvature. Such couplings are quite generic, arising as renormalization counterterms when quantizing scalar fields in curved spacetime. In this chapter I review recent research on a general class of multifield inflationary models with nonminimal couplings. Models in this class exhibit a strong attractor behavior: across a wide range of couplings and initial conditions, the fields evolve along a single-field trajectory for most of inflation. Across large regions of phase space and parameter space, therefore, models in this general class yield robust predictions for observable quantities that fall squarely within the "sweet spot" of recent observations.Comment: 17pp, 2 figs. References added to match the published version. Published in {\it At the Frontier of Spacetime: Scalar-Tensor Theory, Bell's Inequality, Mach's Principle, Exotic Smoothness}, ed. T. Asselmeyer-Maluga (Springer, 2016), pp. 41-57, in honor of Carl Brans's 80th birthda

    On Inflation with Non-minimal Coupling

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    A simple realization of inflation consists of adding the following operators to the Einstein-Hilbert action: (partial phi)^2, lambda phi^4, and xi phi^2 R, with xi a large non-minimal coupling. Recently there has been much discussion as to whether such theories make sense quantum mechanically and if the inflaton phi can also be the Standard Model Higgs. In this note we answer these questions. Firstly, for a single scalar phi, we show that the quantum field theory is well behaved in the pure gravity and kinetic sectors, since the quantum generated corrections are small. However, the theory likely breaks down at ~ m_pl / xi due to scattering provided by the self-interacting potential lambda phi^4. Secondly, we show that the theory changes for multiple scalars phi with non-minimal coupling xi phi dot phi R, since this introduces qualitatively new interactions which manifestly generate large quantum corrections even in the gravity and kinetic sectors, spoiling the theory for energies > m_pl / xi. Since the Higgs doublet of the Standard Model includes the Higgs boson and 3 Goldstone bosons, it falls into the latter category and therefore its validity is manifestly spoiled. We show that these conclusions hold in both the Jordan and Einstein frames and describe an intuitive analogy in the form of the pion Lagrangian. We also examine the recent claim that curvature-squared inflation models fail quantum mechanically. Our work appears to go beyond the recent discussions.Comment: 14 pages, 2 figures. Version 2: Clarified findings and improved wording. Elaborated important sections and removed an unnecessary section. Added references. Version 3: Updated towards JHEP version. Version 4: Final JHEP versio

    Design, Synthesis, and Anticancer Activity of a Selenium‐Containing Galectin‐3 and Galectin‐9N Inhibitor

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    Galectins are soluble β‐D‐galactoside‐binding proteins whose implication in cancer progression and disease outcome makes them prominent targets for therapeutic intervention. In this frame, the development of small inhibitors that block selectively the activity of galectins represents an important strategy for cancer therapy which is, however, still relatively underdeveloped. To this end, we designed here a rationally and efficiently novel diglycosylated compound, characterized by a selenoglycoside bond and the presence of a lipophilic benzyl group at both saccharide residues. The relatively high binding affinity of the new compound to the carbohydrate recognition domain of two galectins, galectin 3 and galectin 9, its good antiproliferative and anti‐migration activity towards melanoma cells, as well as its anti‐angiogenesis properties, pave the way for its further development as an anticancer agent
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