472 research outputs found

    The Famous Marks Exception to the Territoriality Principle in American Trademark Law

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    Risen Land

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    The sculptures I create are inspired by derelict manufactured spaces found within Bulloch County. Each object is created in Tabby, a historic building material comprised of oyster shells, lime, sand and water, commonly known as ‘the first American concrete.’ Tabby was often used in the Coastal South, speaking to the resourceful tradition of using available aggregates. The sculptures embrace the tonal and textural qualities provided by this material to yield ghost-like representations of architectural components while also referencing commercial and historic methods of construction. Serving as a monument to the diverse history of each site, every sculpture is fabricated based on the scale of the original architecture. Whether the selection is derived from personal, commercial, or historical interest, preserving the specified sense of the structure always remains paramount. Within each sculpture, sections are intentionally left missing to reference a hindered capacity for each architectural component to fulfill its intended function. By focusing on facades in ruin, the works act as a metaphor for neglect, loss, transition and transformation

    Networks and History

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    Events and event structures compose the constituent elements of history. In order to construct historical accounts of event sequences, historians have to make cases. This article proposes a method for casing historical events. We illustrate the analytic strategy by considering a complex population of interrelated events that make up a narrative of revolution, counter revolution, and revolution in a small village in China. Implications for the methodology of historical social science are discussed

    The Current State of the Pediatric Emergency Medicine Workforce and Innovations to Improve Pediatric Care

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    Many hospitals and emergency departments lack resources to optimally care for ill and injured children, perpetuating risks of receiving fragmented and “uneven” care. In this article, we describe the present state of our pediatric emergency medicine workforce as well as the impact that different innovations could have on the future of pediatric emergency care. Many innovative initiatives, including physician and advanced practice provider education and training, pediatric readiness recognition programs, telemedicine and in-situ simulation outreach, and community paramedicine are being utilized to help bridge access gaps and augment the reach of the pediatric emergency medicine workforce. Advocacy for reimbursement for novel care delivery models, such as community paramedicine and telemedicine, and funding for outreach education programming is essential. Also, better understanding of our current training models for and utilization of advanced practice practitioners in pediatric emergency medicine is crucial to understanding the diversity of workforce growth and opportunity

    The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases

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    Despite the discovery of 5 alpha-reduction as an enzymatic step in steroid metabolism in 1951, and the discovery that dihydrotestosterone is more potent than testosterone in 1968, the significance of 5 alpha-reduced steroids in human diseases was not appreciated until the discovery of 5 alpha-reductase type 2 deficiency in 1974. Affected males are born with ambiguous external genitalia, despite normal internal genitalia. The prostate is hypoplastic, nonpalpable on rectal examination and approximately 1/10th the size of age-matched normal glands. Benign prostate hyperplasia or prostate cancer does not develop in these patients. At puberty, the external genitalia virilize partially, however, secondary sexual hair remains sparse and male pattern baldness and acne develop rarely. Several compounds have been developed to inhibit the 5 alpha-reductase isozymes and they play an important role in the prevention and treatment of many common diseases. This review describes the basic biochemical properties, functions, tissue distribution, chromosomal location, and clinical significance of the 5 alpha-reductase isozyme family

    Marooned on an Extinct Volcano: the Conservation Status of Four Endemic Land Snails (Gastropoda: Pulmonata) at Mount Kaputar, New South Wales

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    Volcanic activity in northern inland New South Wales between 40 and 15 million years ago was followed by general continental-scale drying and coastward contraction of mesic ecosystems between 15 and 2 million years ago. Together, these processes resulted in the creation of high-elevation climatic refuges such as Coolah Tops, Mount Kaputar and the Warrumbungle Range as western outposts of the mesic eastern highlands on the dry western slopes. These areas are important hotspots of land snail species diversity and endemism. A high-elevation and dry rainforest land snail community at Mount Kaputar, recognised as being of outstanding conservation significance, was listed as an endangered ecological community under NSW legislation in 2013. Two species from this community, the Kaputar Pink Slug Triboniophorus sp. nov. “Kaputar” and Bronze Rippled Pinwheel Snail Cralopa kaputarensis , are currently listed on the IUCN Red List , as endangered and data deficient respectively. This paper provides an updated assessment of the conservation status of the Kaputar Pink Slug, a reassessment of the Bronze Rippled Pinwheel Snail and original assessment of another two endemic Mount Kaputar species (Kaputar Carnivorous Snail Vitellidelos kaputarensis and Kaputar Keeled Snail Thersites sp. nov. “Kaputar”), concluding that all four species meet the criteria for listing as endangered on the IUCN Red List

    Coalgebraic Aspects of Bidirectional Computation

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    We have previously (Bx, 2014; MPC, 2015) shown that several statebased bx formalisms can be captured using monadic functional programming, using the state monad together with possibly other monadic effects, giving rise to structures we have called monadic bx (mbx). In this paper, we develop a coalgebraic theory of state-based bx, and relate the resulting coalgebraic structures (cbx) to mbx. We show that cbx support a notion of composition coherent with, but conceptually simpler than, our previous mbx definition. Coalgebraic bisimulation yields a natural notion of behavioural equivalence on cbx, which respects composition, and essentially includes symmetric lens equivalence as a special case. Finally, we speculate on the applications of this coalgebraic perspective to other bx constructions and formalisms
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