51 research outputs found

    Massive MIMO 1-Bit DAC Transmission: A Low-Complexity Symbol Scaling Approach

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    CCBY We study multi-user massive multiple-input singleoutput (MISO) systems and focus on downlink transmission for PSK modulation, where the base station (BS) employs a large antenna array with low-cost 1-bit digital-to-analog converters (DACs). The direct combination of existing beamforming schemes with 1-bit DACs is shown to lead to an error floor at mediumto- high SNR regime, due to the coarse quantization of the DACs with limited precision. In this paper, based on the constructive interference we consider both a quantized linear beamforming scheme where we analytically obtain the optimal beamforming matrix, and a non-linear mapping scheme where we directly design the transmit signal vector. Due to the 1-bit quantization, the formulated optimization for the non-linear mapping scheme is shown to be non-convex. The non-convex constraints of the 1-bit DACs are firstly relaxed into convex, followed by an element-wise normalization to satisfy the 1-bit DAC transmission. We further propose a low-complexity symbol scaling scheme that consists of three stages, in which the quantized transmit signal on each antenna element is selected sequentially. Numerical results show that the proposed symbol scaling scheme achieves a comparable performance to the optimization-based non-linear mapping approach, while the corresponding performance-complexity tradeoff is more favorable for the proposed symbol scaling method

    Utility of whole-genome sequencing during an investigation of multiple foodborne outbreaks of Shigella sonnei

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    In April 2018, Public Health England was notified of cases of Shigella sonnei who had eaten food from three different catering outlets in England. The outbreaks were initially investigated as separate events, but whole-genome sequencing (WGS) showed they were caused by the same strain. The investigation included analyses of epidemiological data, the food chain and microbiological examination of food samples. WGS was used to determine the phylogenetic relatedness and antimicrobial resistance profile of the outbreak strain. Ultimately, 33 cases were linked to this outbreak; the majority had eaten food from seven outlets specialising in Indian or Middle Eastern cuisine. Five outlets were linked to two or more cases, all of which used fresh coriander although a shared supplier was not identified. An investigation at one of the venues recorded that 86% of cases reported eating dishes with coriander as an ingredient or garnish. Four cases were admitted to hospital and one had evidence of treatment failure with ciprofloxacin. Phylogenetic analysis showed that the outbreak strain was part of a wider multidrug-resistant clade associated with travel to Pakistan. Poor hygiene practices during cultivation, distribution or preparation of fresh produce are likely contributing factors
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