133 research outputs found

    Attractor switching by neural control of chaotic neurodynamics

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    Model-independent approach to eta -> pi+ pi- gamma and eta' -> pi+ pi- gamma

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    We present a new, model-independent method to analyze radiative decays of mesons to a vector, isovector pair of pions of invariant mass square below the first significant pion-pion threshold in the vector channel. It is based on a combination of chiral perturbation theory and dispersion theory. This allows for a controlled inclusion of resonance physics without the necessity to involve vector meson dominance explicitly. As an example, the method is applied to an analysis of the reactions eta -> pi+ pi- gamma and eta'->pi+ pi- gamma.Comment: 16 pages, 4 figure

    Optimal vaccine allocation for the control of sexually transmitted infections

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    The burden of sexually transmitted infections (STIs) poses a challenge due to its large negative impact on sexual and reproductive health worldwide. Besides simple prevention measures and available treatment efforts, prophylactic vaccination is a powerful tool for controlling some viral STIs and their associated diseases. Here, we investigate how prophylactic vaccines are best distributed to prevent and control STIs. We consider sex-specific differences in susceptibility to infection, as well as disease severity outcomes. Different vaccination strategies are compared assuming distinct budget constraints that mimic a scarce vaccine stockpile. Vaccination strategies are obtained as solutions to an optimal control problem subject to a two-sex Kermack– McKendrick-type model, where the control variables are the daily vaccination rates for females and males. One important aspect of our approach relies on conceptualizing a limited but specific vaccine stockpile via an isoperimetric constraint. We solve the optimal control problem via Pontryagin’sMaximum Principle and obtain a numerical approximation for the solution using a modified version of the forward–backward sweep method that handles the isoperimetric budget constraint in our formulation. The results suggest that for a limited vaccine supply (20%–30%vaccination coverage), onesex vaccination, prioritizing females, appears to be more beneficial than the inclusion of both sexes into the vaccination program.Whereas, if the vaccine supply is relatively large (enough to reach at least 40% coverage), vaccinating both sexes, with a slightly higher rate for females, is optimal and provides an effective and faster approach to reducing the prevalence of the infection

    Dispersive analysis for ηγγ\eta\to \gamma\gamma^*

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    A dispersion integral is derived that connects data on ηπ+πγ\eta\to \pi^+\pi^-\gamma to the ηγγ\eta\to \gamma\gamma^* transition form factor. A detailed analysis of the uncertainties is provided. We find for the slope of the η\eta transition form factor at the origin bη=(2.050.10+0.22)GeV2b_\eta = (2.05 {}^{+0.22}_{-0.10})\, {\rm GeV}^{-2}. Using an additional, plausible assumption, one finds for the corresponding slope of the η\eta' transition form factor, bη=(1.580.08+0.15)GeV2b_{\eta'} = (1.58 {}^{+0.15}_{-0.08})\, {\rm GeV}^{-2}. Both values are consistent with all recent data, but differ from some previous theoretical analyses.Comment: 11 pages, 3 figures, 2 tables (with extended discussion of the isoscalar contribution to the transition form factor

    Разработка метода темплатного синтеза наноструктур в алюмооксидных матрицах

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    Объектом исследования является разработка метода темплатного синтеза наноструктур в алюмооксидных матрицах. Цель работы являются синтез матрицы АОА методом двухступенчатого анодирования и разработка методики темплатного синтеза металлических наноструктур в матрице АОА. Область применения: мембранные технологии, оптика, микроэлектронные устройства, матрицы для темплатного синтеза. В будущем планируется проведение исследования нанокомпозитов на основе кобальта, полученных в матрице АОА, изучение режима формирования наноструктуры и применения таких материалов.The object of research is the development of a template synthesis method for nanostructures in alumina matrices. The aim of the work is the synthesis of the AOA matrix by the method of two-stage anodization and the development of a template synthesis technique for metal nanostructures in the AOA matrix. Scope: membrane technologies, optics, microelectronic devices, matrices for template synthesis. In the future, it is planned to conduct research on cobalt-based nanocomposites obtained in the AOA matrix, to study the regime of nanostructure formation and the use of such materials.In the future, it is planned to conduct research on cobalt-base

    Quasi-Neutral theory of epidemic outbreaks

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    Some epidemics have been empirically observed to exhibit outbreaks of all possible sizes, i.e., to be scalefree or scale-invariant. Different explanations for this finding have been put forward; among them there is a model for "accidental pathogens" which leads to power-law distributed outbreaks without apparent need of parameter fine tuning. This model has been claimed to be related to self-organized criticality, and its critical properties have been conjectured to be related to directed percolation. Instead, we show that this is a (quasi) neutral model, analogous to those used in Population Genetics and Ecology, with the same critical behavior as the voter-model, i.e. the theory of accidental pathogens is a (quasi)-neutral theory. This analogy allows us to explain all the system phenomenology, including generic scale invariance and the associated scaling exponents, in a parsimonious and simple way.Comment: 13 pages, 6 figures Accepted for publication in PLoS ONE the text have been modified in orden to improve the figure's resolutio

    Surface electrons at plasma walls

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    In this chapter we introduce a microscopic modelling of the surplus electrons on the plasma wall which complements the classical description of the plasma sheath. First we introduce a model for the electron surface layer to study the quasistationary electron distribution and the potential at an unbiased plasma wall. Then we calculate sticking coefficients and desorption times for electron trapping in the image states. Finally we study how surplus electrons affect light scattering and how charge signatures offer the possibility of a novel charge measurement for dust grains.Comment: To appear in Complex Plasmas: Scientific Challenges and Technological Opportunities, Editors: M. Bonitz, K. Becker, J. Lopez and H. Thomse

    Smoking and health-related quality of life in English general population: Implications for economic evaluations

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    Copyright @ 2012 Vogl et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.This article has been made available through the Brunel Open Access Publishing Fund.Background: Little is known as to how health-related quality of life (HRQoL) when measured by generic instruments such as EQ-5D differ across smokers, ex-smokers and never-smokers in the general population; whether the overall pattern of this difference remain consistent in each domain of HRQoL; and what implications this variation, if any, would have for economic evaluations of tobacco control interventions. Methods: Using the 2006 round of Health Survey for England data (n = 13,241), this paper aims to examine the impact of smoking status on health-related quality of life in English population. Depending upon the nature of the EQ-5D data (i.e. tariff or domains), linear or logistic regression models were fitted to control for biology, clinical conditions, socio-economic background and lifestyle factors that an individual may have regardless of their smoking status. Age- and gender-specific predicted values according to smoking status are offered as the potential 'utility' values to be used in future economic evaluation models. Results: The observed difference of 0.1100 in EQ-5D scores between never-smokers (0.8839) and heavy-smokers (0.7739) reduced to 0.0516 after adjusting for biological, clinical, lifestyle and socioeconomic conditions. Heavy-smokers, when compared with never-smokers, were significantly more likely to report some/severe problems in all five domains - mobility (67%), self-care (70%), usual activity (42%), pain/discomfort (46%) and anxiety/depression (86%) -. 'Utility' values by age and gender for each category of smoking are provided to be used in the future economic evaluations. Conclusion: Smoking is significantly and negatively associated with health-related quality of life in English general population and the magnitude of this association is determined by the number of cigarettes smoked. The varying degree of this association, captured through instruments such as EQ-5D, may need to be fed into the design of future economic evaluations where the intervention being evaluated affects (e.g. tobacco control) or is affected (e.g. treatment for lung cancer) by individual's (or patients') smoking status
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